BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0036.0031.p (546 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA4198 [IQ] COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ... 686 0.0 mlr7293 [IQ] COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid... 627 e-179 mlr6974 [IQ] COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid... 506 e-143 DR0336 [IQ] COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ... 380 e-105 VNG0162G [IQ] COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-aci... 280 7e-75 >PA4198 [IQ] COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Pae Pseudomonas aeruginosa Length = 540 Score = 686 bits (1769), Expect = 0.0, Method: Compositional matrix adjust. Identities = 336/539 (62%), Positives = 395/539 (73%), Gaps = 7/539 (1%) Query: 1 MADFDTGLGRNAANYAALTPIDFIARAAAVYGQRPAIIHGALRQDWDQTYRRTRRLASAL 60 M+ F+ GL A N+ ALTP+ FI R A+VY PA+IHG +R+DW QTY+R RRLASAL Sbjct: 1 MSIFEQGLAPAAVNHIALTPLSFIERTASVYPHYPAVIHGNIRRDWAQTYQRCRRLASAL 60 Query: 61 QRLGIGKNDTVSAMLPNTPAMVEAHFGVPMAGAVLNALNIRLDAESIVFMLRHGEAKVLL 120 GIG+ DTV+ MLPN P M+EAH+GVPM GAVLN LN+RLDAE+I FML+HGEAKVL+ Sbjct: 61 AGRGIGQGDTVAVMLPNIPEMLEAHYGVPMIGAVLNTLNVRLDAEAIAFMLQHGEAKVLI 120 Query: 121 IDSEFAALAQQLRTQL--PALKIVEVFDVLGPPPVPGERFGHLEYEALLADGDENFEWQW 178 D EF + L P L V DV P G G L+YEALLA+GD F W+W Sbjct: 121 TDYEFHEVIHAAIGMLDHPPL----VVDVNDPEYGEGRPVGELDYEALLAEGDPQFAWEW 176 Query: 179 PADEWDAIALNYTSGTTGDPKGVVYHHRGAALNAVSNILEWDLPKHPVYLWTLPMFHCNG 238 P DEW AI+LNYTSGTTG+PKGVVYHHRGA LNA+ N + W + +HPVYLWTLPMFHCNG Sbjct: 177 PRDEWQAISLNYTSGTTGNPKGVVYHHRGAYLNALGNQMTWSMGQHPVYLWTLPMFHCNG 236 Query: 239 WCFPWTVAARAGVNVCLRKFDPKLVFDLIAEHGITHYCAAPIVHAALANAPEGWRAGIRG 298 WC+PWTV A AGV+VCLR+ DP+ V LI EH ++H C APIV AL N P+ +A I Sbjct: 237 WCYPWTVTALAGVHVCLRRVDPQKVLTLIREHQVSHLCGAPIVLNALINMPDSAKAAIDH 296 Query: 299 PVKAMVAGAPPPAAVLAKMEAMQFELTHVYGLTEVYGPAAVCAEQDEWSTLSVDQRAVQK 358 PV AMVAGA PPA V+ +E M +THVYGLTEVYGP VCA EW L +++RA K Sbjct: 297 PVHAMVAGAAPPAKVIGAVEEMGIRVTHVYGLTEVYGPVTVCAWHGEWDDLPLERRAAIK 356 Query: 359 SRQGVRYHLQSGVTVLSPDTMEPVAADGEEIGEIMFRGNICMKGYLKNDKATHEAFAGGW 418 SRQGVRY GV V P T+EPV DG+ IGEI RGN MKGYLKN AT EAFAGGW Sbjct: 357 SRQGVRYPTLEGVMVADPKTLEPVPRDGQSIGEIFMRGNTVMKGYLKNPSATEEAFAGGW 416 Query: 419 FHTGDLGVMNADGYIKIKDRSKDIIISGGENISSVEVEDVLYRHPAVLAAAVVAQPDEKW 478 FHTGDL V + DGYI+I+DR KDIIISGGENIS++E+E VLYRHPAVL AAVVA+PDEKW Sbjct: 417 FHTGDLAVCHPDGYIEIRDRLKDIIISGGENISTIELEGVLYRHPAVLEAAVVARPDEKW 476 Query: 479 GETPCAFVELK-DGANIDAAELTEFCRGHLAGFKVPKAIYFGPLPKTSTGKIQKFELRK 536 GETPCAF+ LK D + +E+ FCR HLA FK+P+ + F LPKTSTGKIQK+ LR+ Sbjct: 477 GETPCAFITLKSDHQGLAESEIVAFCREHLAAFKIPRTVVFSELPKTSTGKIQKYVLRE 535 >mlr7293 [IQ] COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Mlo Mesorhizobium loti Length = 546 Score = 627 bits (1618), Expect = e-179, Method: Compositional matrix adjust. Identities = 310/546 (56%), Positives = 383/546 (70%), Gaps = 16/546 (2%) Query: 4 FDTGLGRNAANYAALTPIDFIARAAAVYGQRPAIIHGALRQDWDQTYRRTRRLASALQRL 63 ++ L RNAAN+ LTP+ ++ RAA Y AIIHG R + +RR+ ++ASALQ+ Sbjct: 5 YEQDLDRNAANHQPLTPLTYLERAAKTYPDHIAIIHGRQRISYRDFWRRSLKVASALQKR 64 Query: 64 GIGKNDTVSAMLPNTPAMVEAHFGVPMAGAVLNALNIRLDAESIVFMLRHGEAKVLLIDS 123 GIGK DTV+ ML NTP M+EAHFGVPM AVL++LN RLDA I F L H E KVL++D Sbjct: 65 GIGKGDTVTVMLSNTPPMLEAHFGVPMTKAVLHSLNTRLDAAVIAFQLDHAETKVLIVDR 124 Query: 124 EFAALAQQLRTQLPALKIVEVFDVL----------GPPPVPGERFGHLEYEALLADGDEN 173 EF+ + +Q AL + +V ++ P GER G L+YE +A GDE+ Sbjct: 125 EFSGVVRQ------ALDLAKVTPLVIDYDDPDYAADAPYPKGERIGALDYEDFVAGGDED 178 Query: 174 FEWQWPADEWDAIALNYTSGTTGDPKGVVYHHRGAALNAVSNILEWDLPKHPVYLWTLPM 233 F W P DEWDAI+LNYTSGTTG+PKGVVYHHRGAAL A +N + + KH VYLWTLPM Sbjct: 179 FAWSMPDDEWDAISLNYTSGTTGNPKGVVYHHRGAALMAYTNTIHAGMAKHAVYLWTLPM 238 Query: 234 FHCNGWCFPWTVAARAGVNVCLRKFDPKLVFDLIAEHGITHYCAAPIVHAALANAPEGWR 293 FHCNGWCFPWT+A +AG +VCLR PK ++D IA+HG+TH C AP+V + L NA + + Sbjct: 239 FHCNGWCFPWTLAVQAGTHVCLRWVRPKPIYDAIADHGVTHLCGAPVVMSVLINARDEDK 298 Query: 294 AGIRGPVKAMVAGAPPPAAVLAKMEAMQFELTHVYGLTEVYGPAAVCAEQDEWSTLSVDQ 353 V A APPP AVL+ M F +TH+YGLTE YGPA V EW L+ + Sbjct: 299 RTFAQTVTFNTAAAPPPEAVLSGMADAGFAVTHLYGLTETYGPAVVNEWHGEWDDLAKGE 358 Query: 354 RAVQKSRQGVRYHLQSGVTVLSPDTMEPVAADGEEIGEIMFRGNICMKGYLKNDKATHEA 413 R+ +K+RQGVRY G+TV+ P+TM+ ADGE IGE+MFRGNI MKGYLKN KA+ EA Sbjct: 359 RSAKKARQGVRYAALEGLTVMDPETMQATPADGETIGEVMFRGNIVMKGYLKNRKASDEA 418 Query: 414 FAGGWFHTGDLGVMNADGYIKIKDRSKDIIISGGENISSVEVEDVLYRHPAVLAAAVVAQ 473 FAGGWFH+GDLGVM+ DGYI++KDRSKDIIISGGENISS+EVED LY+HP+V + VVA+ Sbjct: 419 FAGGWFHSGDLGVMHPDGYIQLKDRSKDIIISGGENISSIEVEDALYKHPSVASCGVVAR 478 Query: 474 PDEKWGETPCAFVELKDGANIDAAELTEFCRGHLAGFKVPKAIYFGPLPKTSTGKIQKFE 533 D+KWGE P A+VELK G AE+ E CR LA FKVPKA+ F +PKTSTGKIQKF Sbjct: 479 HDDKWGEVPVAYVELKPGKTASEAEIIEHCRALLARFKVPKAVIFAEIPKTSTGKIQKFR 538 Query: 534 LRKRMK 539 LR+ K Sbjct: 539 LREMAK 544 >mlr6974 [IQ] COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Mlo Mesorhizobium loti Length = 541 Score = 506 bits (1302), Expect = e-143, Method: Compositional matrix adjust. Identities = 256/527 (48%), Positives = 332/527 (62%), Gaps = 6/527 (1%) Query: 10 RNAANYAALTPIDFIARAAAVYGQRPAIIHGALRQDWDQTYRRTRRLASALQRLGIGKND 69 R+ AN AL+P+ F+ RA VYG R A+ +G +R+ W QT R R +A+ L LG+G D Sbjct: 10 RDDANCVALSPLSFLKRAELVYGARSAVTYGDVRRTWAQTGARCRSVAAGLAALGVGPGD 69 Query: 70 TVSAMLPNTPAMVEAHFGVPMAGAVLNALNIRLDAESIVFMLRHGEAKVLLIDSEFAALA 129 TVS + PN P + E H+ VP+ GAVLN +N RL+ E++ ++L H ++ +++ D+ FA L Sbjct: 70 TVSVLSPNIPELFELHYAVPLLGAVLNTINTRLEPETVAYILAHSDSTLVIADTAFAPLL 129 Query: 130 QQ-LRTQLPALKIVEVFDVLGPPPVPGERFGHLEYEALLADGDENFEWQWPADEWDAIAL 188 ++ R L +V+V D FG YE L A W+ P DEW A+AL Sbjct: 130 REAFRLNGNTLPVVDVVDAQAQA---SAEFGERSYEDLAAH--PPMGWELPKDEWQALAL 184 Query: 189 NYTSGTTGDPKGVVYHHRGAALNAVSNILEWDLPKHPVYLWTLPMFHCNGWCFPWTVAAR 248 NYTSGT+G PKGV+YHHRGA L A+ I W LP+HP YL +PMFHCNGW PW++A Sbjct: 185 NYTSGTSGRPKGVIYHHRGAYLMAMGTIAAWALPQHPTYLSVVPMFHCNGWTHPWSMAIV 244 Query: 249 AGVNVCLRKFDPKLVFDLIAEHGITHYCAAPIVHAALANAPEGWRAGIRGPVKAMVAGAP 308 V R P + + +A H +TH AAPIV L + ++ M AGAP Sbjct: 245 GANMVFTRDASPGKLLEAMAAHRVTHMGAAPIVLQMLCDGRGASAQPFNPQIRVMTAGAP 304 Query: 309 PPAAVLAKMEAMQFELTHVYGLTEVYGPAAVCAEQDEWSTLSVDQRAVQKSRQGVRYHLQ 368 PP AVL K M ++ VYGLTE YG + C QDEW LSV RA +++ QGV + + Sbjct: 305 PPPAVLEKAAQMGLDVMQVYGLTETYGHISQCLWQDEWEALSVSARAEKQAMQGVAFPMV 364 Query: 369 SGVTVLSPDTMEPVAADGEEIGEIMFRGNICMKGYLKNDKATHEAFAGGWFHTGDLGVMN 428 + V+ DT V DG GEI RGN MKGY K+ +T AF GWF +GD V++ Sbjct: 365 EDIRVVDRDTGTDVPRDGLTQGEIAIRGNTVMKGYYKDATSTAAAFESGWFWSGDAAVVH 424 Query: 429 ADGYIKIKDRSKDIIISGGENISSVEVEDVLYRHPAVLAAAVVAQPDEKWGETPCAFVEL 488 DGYI+I+DR KD+IISGGENISSVEVE VLYRHPA+ AAVVA+P KWGE+PCAFVEL Sbjct: 425 PDGYIQIRDRLKDVIISGGENISSVEVESVLYRHPAISVAAVVARPHPKWGESPCAFVEL 484 Query: 489 KDGANIDAAELTEFCRGHLAGFKVPKAIYFGPLPKTSTGKIQKFELR 535 ++GA+ AE+ FCR ++A FK PK + FGPLPKT+TGKIQKF LR Sbjct: 485 REGASATEAEIIAFCRANIAHFKAPKTVVFGPLPKTATGKIQKFILR 531 >DR0336 [IQ] COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Dra Deinococcus radiodurans Length = 524 Score = 380 bits (976), Expect = e-105, Method: Compositional matrix adjust. Identities = 234/526 (44%), Positives = 305/526 (57%), Gaps = 22/526 (4%) Query: 18 LTPIDFIARAAAVYGQRPAIIH-GALRQDWDQTYRRTRRLASALQRLGIGKNDTVSAMLP 76 LTP+ + R +Y A+I G R + + RR +LA A+Q G G V+ + P Sbjct: 7 LTPLTLVRRGLKLYPDHTAVIEPGGPRFTYREWGRRIYQLARAIQAAGYGGQH-VAVLSP 65 Query: 77 NTPAMVEAHFGVPMAGAVLNALNIRLDAESIVFMLRHGEAKVLLIDSEFAALAQQLRTQL 136 NT + + GVP AG+VL LN RL E F LRH E ++LL+D +L ++R Sbjct: 66 NTHGGLLTYAGVPWAGSVLVPLNTRLTPEEYEFQLRHAEVRLLLVDE---SLHDRVREVA 122 Query: 137 PALKIVEVFDVLGPPPVPGERFGHLEYEALLADGDENFEWQWPADEWDAIALNYTSGTTG 196 L I EV+ V+G R +EA LA D++ DE I LN+TSGTT Sbjct: 123 AGLGI-EVW-VMG-----DARGAGTAFEAKLAAQDDSPLPLPVQDENGTITLNFTSGTTS 175 Query: 197 DPKGVVYHHRGAALNAVSNILEWDLPKHPVYLWTLPMFHCNGWCFPWTVAARAGVNVCLR 256 DPKGV+ HR LNA+ I + + VYL TLP FH NGW W+ +V L Sbjct: 176 DPKGVMMTHRSTMLNAIETIYYFKADQDTVYLHTLPDFHANGWGGVWSPFGVGATHVTLP 235 Query: 257 KFDPKLVFDLIAEHGITHYCAAPIVHAALANAPEGWRAGIRGPVKAMVAGAPPPAAVLAK 316 +D I +HG+TH CAAP V + L + P R R ++ AG+PP A ++A Sbjct: 236 TVRADAAYDAIEQHGVTHLCAAPTVLSMLTD-PAHARPLSR-QIRVATAGSPPHARIIAD 293 Query: 317 MEAMQFELTHVYGLTE---VYGPAAVCAEQDEWSTLSVDQRAVQKSRQGVRYHLQSGVTV 373 M A+ F +T VYGLTE + A + A+Q+E L +RA ++QGV L V V Sbjct: 294 MNALGFHVTQVYGLTETSPLITVAELSAQQEE---LPTPRRAALIAKQGVEMILAGEVEV 350 Query: 374 LSPDTMEPVAADGEEIGEIMFRGNICMKGYLKNDKATHEAFAGGWFHTGDLGVMNADGYI 433 L P+ + PV DGE +GEIM RGN+ MKGY +N++AT +A GGWFHTGD+ V++ DG I Sbjct: 351 LDPE-LRPVPGDGETLGEIMVRGNLVMKGYYRNEEATAKALEGGWFHTGDVAVVHPDGRI 409 Query: 434 KIKDRSKDIIISGGENISSVEVEDVLYRHPAVLAAAVVAQPDEKWGETPCAFVELKDGAN 493 +I+DR+KD+IISGGENISSVEVE VLY HPAV A VVA P EKWGE PCAF+ L G Sbjct: 410 EIRDRNKDVIISGGENISSVEVEGVLYAHPAVREAVVVAMPHEKWGEVPCAFIALHQGQE 469 Query: 494 IDAAELTEFCRGHLAGFKVPKAIYF-GPLPKTSTGKIQKFELRKRM 538 + +LT R HLAGFKVPK F LPKT++GK QKF LR + Sbjct: 470 VTPEDLTAHVREHLAGFKVPKHYEFRDDLPKTASGKFQKFILRAEL 515 >VNG0162G [IQ] COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Hbs Halobacterium sp. NRC-1 Length = 600 Score = 280 bits (715), Expect = 7e-75, Method: Compositional matrix adjust. Identities = 192/531 (36%), Positives = 261/531 (49%), Gaps = 24/531 (4%) Query: 18 LTPIDFIARAAAVYGQRPAIIHGALRQ-DWDQTYRRTRRLASALQRLGIGKNDTVSAMLP 76 L DFI RA YG A++ R+ + + R R ++ LQ GI D V+ + P Sbjct: 67 LLVTDFIDRARTYYGDETAVVATTGRRYTYSELADRADRFSAVLQAAGIDSGDRVAVLDP 126 Query: 77 NTPAMVEAHFGVPMAGAVLNALNIRLDAESIVFMLRHGEAKVLLIDSEFAALAQQLRTQL 136 NT +EA +G GA+ LN RL + ++L A + D+ +A + +R Q+ Sbjct: 127 NTHYHLEAAYGAMQLGAIHTPLNYRLTPDDYAYILADAGADAIYADAAYADRVEAVRDQI 186 Query: 137 PALKIVEVFDVLGPPPVPGERFGHLEYEALLADGDENFEWQWP-ADEWDAIALNYTSGTT 195 P F P V G+ + L + ++ P E D I +NYTSGTT Sbjct: 187 P----TTTFITDDPAAVDGD----WQDADALLADADPDDYDRPDMAEDDVITINYTSGTT 238 Query: 196 GDPKGVVYHHRGAALNAVSNILEWDLPKHPVYLWTLPMFHCNGWCFPWTVAARAGVNVCL 255 GDPKGV HR ++A+ + YLWTLPMFH NGW + + +VC Sbjct: 239 GDPKGVCRTHRNEVVHALLLSTHHTITDTDTYLWTLPMFHANGWGHIFAITGAGATHVCT 298 Query: 256 RKFDPKLVFDLIAEHGITHYCAAPIVHAALANAPEGWRAGIRG--PVKAMVAGAPPPAAV 313 R D VFD I +++ CAAP V L + E G V+ AG+ PP A Sbjct: 299 RGVDAASVFDTIQAEAVSYLCAAPTVLNMLLDYHEAHDVAATGDADVRVATAGSAPPEAT 358 Query: 314 LAKME-AMQFELTHVYGLTEVYGPAAVCAEQDEWSTLSVDQRAVQKSRQGVRYHLQSGVT 372 + +E A+ + L HVYG TE GP ++ D RA + RQG+ L + + Sbjct: 359 IRAVESALDWSLMHVYGATET-GPLIATSDADRLLAAGGGSRAAMQKRQGIGL-LGTELR 416 Query: 373 VLSPDTMEPVAADGEEIGEIMFRGNICMKGYLKNDKATHEAFA---GGWFHTGDLGVMNA 429 V+ + V D E IGEI+ GN M Y AT AF G+FH GD V++ Sbjct: 417 VVDEHGND-VPRDNETIGEIVVSGNQVMDRYWNKPDATERAFTDRVDGYFHMGDFAVVDD 475 Query: 430 DGYIKIKDRSKDIIISGGENISSVEVEDVLYRHPAVLAAAVVAQPDEKWGETPCAFVELK 489 G++ I DR KDIIISGGENISS+E+ED L+ H AV AVV P + WGETP AFV Sbjct: 476 TGFVSILDRKKDIIISGGENISSIELEDTLFEHDAVGEVAVVPSPHDDWGETPKAFVVPA 535 Query: 490 DG----ANIDAAELTEFCRGHLAGFKVPKAIYF-GPLPKTSTGKIQKFELR 535 G + L E+ R LA FK + + F LP T+TGK+QK+ELR Sbjct: 536 SGDPNNPGVTTTALVEYTRAELASFKTVRRVEFVDELPTTATGKVQKYELR 586