BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0036.0025.p (407 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2172 [GEPR] COG0477 Permeases of the major facilitator superf... 358 9e-99 PA3573 [GEPR] COG0477 Permeases of the major facilitator superfa... 303 4e-82 CC1230 [GEPR] COG0477 Permeases of the major facilitator superfa... 252 1e-66 YPO1267 [GEPR] COG0477 Permeases of the major facilitator superf... 251 2e-66 Cj0035c [GEPR] COG0477 Permeases of the major facilitator superf... 240 4e-63 >RSc2172 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 407 Score = 358 bits (920), Expect = 9e-99, Method: Compositional matrix adjust. Identities = 189/390 (48%), Positives = 255/390 (65%), Gaps = 1/390 (0%) Query: 11 GKFPPWLAVLAALTALGALAIDMYLPSFTAIAKELGVGTNLVQLTLASFLVGLAVGQMFY 70 G P WL +L ALTA+G L++DMYLPS IA++L + +TL +FLV LA+GQ+ Y Sbjct: 16 GAIPGWLLLLGALTAIGPLSVDMYLPSLPTIARDLRTSSAAAGITLTAFLVSLAIGQLIY 75 Query: 71 GPLSDRFGRKPPLFFGIALYFVCSLLCIFVQSIETLIVLRLFQGLGGSAGMVIPRAMVRD 130 GP SDRFGRKPPL+ G+ALY S+ C F L VLR QG GG AGMVI RA VRD Sbjct: 76 GPASDRFGRKPPLYIGLALYVAASVGCAFATDATMLAVLRAVQGFGGCAGMVISRAAVRD 135 Query: 131 RMGAEGSAKAFSMLMLVFGLAPILAPFIGGLMLVFASWRGIFVVLTIFGLLCMLGTRKYL 190 RM G+A+A+S LMLV G+APILAP IGG +L SWR IF VL FG+L + + Sbjct: 136 RMDPAGAAQAYSTLMLVMGVAPILAPMIGGAVLQVTSWRMIFAVLAAFGVLSLAAVHFLM 195 Query: 191 TETVDVSRAEPLHLGRTLRQYWGLLRHRQFMSFVLCGGLVQAGMFAYIAGGPFVVIELHG 250 E++D + A PL +GR LR YW LLR R + ++ CG + +GMFAYI PFV+I+ +G Sbjct: 196 RESLDAAHARPLAVGRVLRDYWELLRDRHYAAYTACGAVFVSGMFAYITASPFVLIDHYG 255 Query: 251 IKPQYFGFVFASNAIGLIAASQINARLVVKRSAERVLGKVLWVPAGLSLAVVLAVLAGLE 310 + P ++ +VF SNA G+IAAS+IN RL+ + + RVL + LW+PA S+A V AG Sbjct: 256 LSPSHYAWVFGSNAAGMIAASRINVRLMRRSTPARVLRRALWMPAATSVAAAAVVGAGFM 315 Query: 311 SLPLLLFGFFGFLTAYGFTGPNATAIALKHQGRQAGTAAALMGTLQFGMGVLSGVVMSLW 370 LPL+L F ++ + G PN A+A+ QG +AGT +ALMG +QFG+G+++G V++ + Sbjct: 316 PLPLVLAALFCYVASIGCISPNTGALAMAGQGARAGTGSALMGAMQFGLGMVTGTVVAAF 375 Query: 371 HDGTALPLVSVMAICGVSAFLLYHFVAKHE 400 G A PL+ +MA+ V A L +HE Sbjct: 376 GQGAA-PLLGMMAVSAVLALWLGLRATQHE 404 >PA3573 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 392 Score = 303 bits (777), Expect = 4e-82, Method: Compositional matrix adjust. Identities = 174/386 (45%), Positives = 241/386 (62%), Gaps = 5/386 (1%) Query: 17 LAVLAALTALGALAIDMYLPSFTAIAKELGVGTNLVQLTLASFLVGLAVGQMFYGPLSDR 76 L +L AL+A G LAID YLPSF +AK VQL+LA++ GL++GQ+ YGP++DR Sbjct: 6 LLILGALSAFGPLAIDFYLPSFPTLAKAFATDVEHVQLSLAAYFAGLSIGQLLYGPVADR 65 Query: 77 FGRKPPLFFGIALYFVCSLLCIFVQSIETLIVLRLFQGLGGSAGMVIPRAMVRDRMGAEG 136 +GR+ PL G++++ + S C S+E LI R Q LGG AGMVI RA+VRD G Sbjct: 66 YGRRLPLLVGVSIFTLASAACALAPSLEWLIAARFVQALGGCAGMVISRAVVRDLCDPIG 125 Query: 137 SAKAFSMLMLVFGLAPILAPFIGGLMLVFASWRGIFVVLTIFGLLCMLGTRKYLTETVDV 196 +AKAFS LMLV GLAPILAP GGL+L + W+ IFV LT+F L LG +L ET+ Sbjct: 126 AAKAFSQLMLVMGLAPILAPVAGGLLLDWQGWQSIFVCLTLFAALAGLGVALWLPETIPA 185 Query: 197 SRAEPLHLGRTLRQYWGLLRHRQFMSFVLCGGLVQAGMFAYIAGGPFVVIELHGIKPQYF 256 P L L QY L R F+++ L GG+ AGMFAYIAG P+V I+L+GI +++ Sbjct: 186 DGERP-PLSGALGQYRRLFADRLFLAYGLSGGVAMAGMFAYIAGSPYVFIQLYGIPAEHY 244 Query: 257 GFVFASNAIGLIAASQINARLVVKRSAERVLGKVLWVPAGLSLAVVLAVLAGLESLPL-- 314 G++F SNA G I +Q+NARL+ R L +++W L+ + L +A L+ L Sbjct: 245 GWLFGSNAAGFIVMAQVNARLLRYRGPAFWLRRIIW--GYLACGLALLGIASLQPATLWP 302 Query: 315 LLFGFFGFLTAYGFTGPNATAIALKHQGRQAGTAAALMGTLQFGMGVLSGVVMSLWHDGT 374 LL FG + + G PNA+A A+ QG+ AG+A+ALMG+LQF + + ++ + HDGT Sbjct: 303 LLVPLFGCVASLGCIIPNASACAMAGQGQHAGSASALMGSLQFSVAAGASALVGVLHDGT 362 Query: 375 ALPLVSVMAICGVSAFLLYHFVAKHE 400 A+P+ V+A+CG A LL + E Sbjct: 363 AIPMTLVIAVCGAVATLLAWQTGRLE 388 >CC1230 [GEPR] COG0477 Permeases of the major facilitator superfamily Ccr Caulobacter vibrioides Length = 405 Score = 252 bits (644), Expect = 1e-66, Method: Compositional matrix adjust. Identities = 150/373 (40%), Positives = 209/373 (56%), Gaps = 2/373 (0%) Query: 15 PWLAVL--AALTALGALAIDMYLPSFTAIAKELGVGTNLVQLTLASFLVGLAVGQMFYGP 72 PW VL ALTA ++IDMYL S +I + L + Q TLA+F G+A+GQ+FYGP Sbjct: 12 PWRLVLLLGALTAFAPMSIDMYLSSLPSIGRTLNAAPDQTQATLAAFFAGMAIGQVFYGP 71 Query: 73 LSDRFGRKPPLFFGIALYFVCSLLCIFVQSIETLIVLRLFQGLGGSAGMVIPRAMVRDRM 132 SDRFGR+PPL G+ L+ S++C +IETLI R Q LGG AG VI RA+VRDR Sbjct: 72 ASDRFGRRPPLLVGVGLFIAASIVCAVAPNIETLIAARFVQALGGCAGPVIARAVVRDRF 131 Query: 133 GAEGSAKAFSMLMLVFGLAPILAPFIGGLMLVFASWRGIFVVLTIFGLLCMLGTRKYLTE 192 +A+ S++ L+ GLAP+LAP +GG++ A WRG+F L +FG+L LTE Sbjct: 132 SHTDTARVLSLMTLIMGLAPVLAPQLGGVVQFVAGWRGVFWTLVMFGVLIAAWVVLSLTE 191 Query: 193 TVDVSRAEPLHLGRTLRQYWGLLRHRQFMSFVLCGGLVQAGMFAYIAGGPFVVIELHGIK 252 + + L+ Y L R+ M + L G L A +F YI+G P +V+ +G Sbjct: 192 SRSAATEAQARSENPLKAYVALFGMRRLMGYALAGALNGAVLFTYISGAPDLVMGTYGHS 251 Query: 253 PQYFGFVFASNAIGLIAASQINARLVVKRSAERVLGKVLWVPAGLSLAVVLAVLAGLESL 312 P F VFA NA+G+I ASQIN L+ + + ++VL + +L + LA G Sbjct: 252 PLVFNLVFALNAVGIIGASQINRFLLRRSTPDQVLARASVASIVAALLLTLAAWTGFGGQ 311 Query: 313 PLLLFGFFGFLTAYGFTGPNATAIALKHQGRQAGTAAALMGTLQFGMGVLSGVVMSLWHD 372 +L F L+ YG G N A AL ++AG+ +ALMG+ FG G ++ + HD Sbjct: 312 WTVLPLLFAALSLYGLMGGNTMAGALSVDPQRAGSTSALMGSASFGAGAVASWAGAALHD 371 Query: 373 GTALPLVSVMAIC 385 GT P+ VM C Sbjct: 372 GTPRPVAGVMFAC 384 >YPO1267 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 399 Score = 251 bits (641), Expect = 2e-66, Method: Compositional matrix adjust. Identities = 145/387 (37%), Positives = 232/387 (59%), Gaps = 3/387 (0%) Query: 19 VLAALTALGALAIDMYLPSFTAIAKELGVGTNLVQLTLASFLVGLAVGQMFYGPLSDRFG 78 +L L+ L LAIDMYLPS IA+E GV + VQ+TL+++++G A+GQMFYGP++D G Sbjct: 14 ILGLLSMLMPLAIDMYLPSMPIIAQEFGVESGRVQMTLSAYVLGFAIGQMFYGPMADSIG 73 Query: 79 RKPPLFFGIALYFVCSLLCIFVQSIETLIVLRLFQGLGGSAGMVIPRAMVRDRMGAEGSA 138 RKP +F+G ++ + + C VQS+E LI +R GL +A V+ A++RD + + Sbjct: 74 RKPVIFWGTLIFALAGMACALVQSVEQLINMRFLHGLSAAAASVVINALMRDMFTKDEFS 133 Query: 139 KAFSMLMLVFGLAPILAPFIGGLMLVFASWRGIFVVLTIFGLLCMLGTRKYLTETVDVSR 198 + S ++LV +AP+LAP IGG +LV+ SW IF + L+ + ++ ET+ R Sbjct: 134 RMMSFVVLVMTIAPLLAPIIGGALLVWFSWHAIFWTMAGAALVGAVLVALFIQETLPPER 193 Query: 199 AEPLHLGRTLRQYWGLLRHRQFMSFVLCGGLVQAGMFAYIAGGPFVVIELHGIKPQYFGF 258 + HL T+ + L RH++ +S++L G AGMF++++ GPFV I+L+G+ PQ FG+ Sbjct: 194 RQKFHLRTTIGNFGSLFRHKRVLSYMLASGFSFAGMFSFLSAGPFVYIDLNGVSPQNFGY 253 Query: 259 VFASNAIGLIAASQINARLVVKRSAERVLGKVLWVPAGLSLAVVLAVLAGLESLPLLLFG 318 FA N + L + IN+R V + A ++ L V + + +V+ +AGL L+L G Sbjct: 254 YFALNIVFLFLMTFINSRNVRRFGALKMFRFGLIVQFVMGIWLVVVCVAGLGFWALVL-G 312 Query: 319 FFGFLTAYGFTGPNATAIALKHQGRQAGTAAALMGTLQFGMGVLSGVVMSLWHDGTALPL 378 ++ NA A+ L AGTA++L GTL+FG+G + G ++S+ +A P+ Sbjct: 313 VAAYVGCIAMITSNAMAVILDDFPHMAGTASSLAGTLRFGIGAVVGTLLSMASSRSAWPM 372 Query: 379 VSVMAICGVSAFLLYHFVAK--HEPVT 403 VS MA C + A LLY + ++ H+ V+ Sbjct: 373 VSSMAFCIIVAMLLYLYASRPSHKTVS 399 >Cj0035c [GEPR] COG0477 Permeases of the major facilitator superfamily Cje Campylobacter jejuni Length = 400 Score = 240 bits (612), Expect = 4e-63, Method: Compositional matrix adjust. Identities = 132/387 (34%), Positives = 211/387 (54%), Gaps = 5/387 (1%) Query: 17 LAVLAALTALGALAIDMYLPSFTAIAKELGVGTNLVQLTLASFLVGLAVGQMFYGPLSDR 76 + +LA ++++ L+ DMYLP+ + + + + L QL++ASF + A+GQ+ YGPLSD Sbjct: 16 IVILALMSSIAPLSTDMYLPALSHVEQSFQTNSFLTQLSIASFFIAFALGQLIYGPLSDI 75 Query: 77 FGRKPPLFFGIALYFVCSLLCIFVQSIETLIVLRLFQGLGGSAGMVIPRAMVRDRMGAEG 136 FGRK P GI + V SL C+ + I I LR F+ LGG AG+VI RA+V D + Sbjct: 76 FGRKIPALVGIFFFIVSSLFCVIIDDIYAFIALRFFEALGGCAGVVIARAIVNDLFEIKE 135 Query: 137 SAKAFSMLMLVFGLAPILAPFIGGLMLVFASWRGIFVVLTIFGLLCMLGTRKYLTETVDV 196 +A F+++M+ LAP+L+P GG++L + SW IF L G+L L L E+ Sbjct: 136 AAGIFALMMVFSSLAPMLSPTFGGILLEYFSWHSIFATLFALGILLFLMILFGLKESAPH 195 Query: 197 SRAEPLHLGRTLRQYWGLLRHRQFMSFVLCGGLVQAGMFAYIAGGPFVVIELHGIKPQYF 256 + + ++ Y +L ++F+ ++LC A MFAYI G FV + + Q F Sbjct: 196 LKNKKFSHHEAMKSYKFVLSDKRFLVYILCASFALAAMFAYITGSSFVFTQFFSLSEQKF 255 Query: 257 GFVFASNAIGLIAASQINARLVVKRSAERVLGKVLWVPAGLSLAVVLAVLAGLESLPLLL 316 +F +NA+G + + INARLV+K +E++L K L + + ++ V+ ++ LL Sbjct: 256 ALLFGANALGFVICANINARLVLKYESEKILAKALMI---MFISTVILLVNAFFHPNFLL 312 Query: 317 F--GFFGFLTAYGFTGPNATAIALKHQGRQAGTAAALMGTLQFGMGVLSGVVMSLWHDGT 374 F F + GF PN T +A+ +GTA+A++GT+QFG L V+ + T Sbjct: 313 FELSIFTSIAMLGFIAPNTTTLAMARFKEHSGTASAVLGTVQFGFAGLISFVVGAINANT 372 Query: 375 ALPLVSVMAICGVSAFLLYHFVAKHEP 401 + L VM C + A ++Y + E Sbjct: 373 PIILAFVMCACVLVANMIYFLIKIKEK 399