BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0123.p (247 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0540 [R] COG2334 Putative homoserine kinase type II (protein ... 269 6e-72 PA0486 [R] COG2334 Putative homoserine kinase type II (protein k... 198 1e-50 YPO0014 [R] COG2334 Putative homoserine kinase type II (protein ... 198 1e-50 VC0035 [R] COG2334 Putative homoserine kinase type II (protein k... 183 4e-46 STM3996 [R] COG2334 Putative homoserine kinase type II (protein ... 177 2e-44 >RSc0540 [R] COG2334 Putative homoserine kinase type II (protein kinase fold) Rso Ralstonia solanacearum Length = 347 Score = 269 bits (687), Expect = 6e-72, Method: Compositional matrix adjust. Identities = 132/214 (61%), Positives = 159/214 (74%), Gaps = 3/214 (1%) Query: 11 PDATS--FATLSPDTVLDALDGLGLYGDGRLLALNSYENRVYQVGMEDGPPLVAKFYRPL 68 PDA+ +A L+PD++LDAL +G DGR+ ALNSYENRVYQ G+EDG P+V KFYRP Sbjct: 10 PDASEAPYAGLTPDSILDALAQVGRMPDGRMFALNSYENRVYQAGIEDGAPVVVKFYRPG 69 Query: 69 RWSDEQILEEHAFSQELADEEVPVVPAMRLDNGATLHRHAGFRFAVFRRHGGRAPELDDA 128 RW+D QI+EEHAF+ ELA E+PVV + +D G TLH + FAVF R GR P +D Sbjct: 70 RWNDAQIVEEHAFTAELAAAEIPVVAPLEID-GRTLHAFDRWHFAVFPRCAGRVPAIDRD 128 Query: 129 DTLERLGRFIGRIHAVGLRSPFQSRPALDIASFGEEPRDWLLAHDFIPMDVATAWRTTVE 188 DTLE +GRF+GRIHAVG R PF +RP LDI +FG + RDWLL HDFIP D+ AWR+ + Sbjct: 129 DTLEWMGRFLGRIHAVGARRPFMARPTLDIDTFGVQSRDWLLEHDFIPPDLLPAWRSVAD 188 Query: 189 QALDGVRRCYERAGEIRTLRLHGDCHVGNVLWTD 222 ALDGVRRCY+RAGE+ LRLHGDCH NVLW D Sbjct: 189 AALDGVRRCYDRAGEVAMLRLHGDCHASNVLWID 222 >PA0486 [R] COG2334 Putative homoserine kinase type II (protein kinase fold) Pae Pseudomonas aeruginosa Length = 324 Score = 198 bits (503), Expect = 1e-50, Method: Compositional matrix adjust. Identities = 111/209 (53%), Positives = 139/209 (66%), Gaps = 6/209 (2%) Query: 16 FATLSPDTVLDALDGLGLYGDGRLLALNSYENRVYQVGMEDGPPLVAKFYRPLRWSDEQI 75 F L+PD VLDA++ LG D R+LALNSYENRVYQVG+EDG PL+AKFYRP RWSD I Sbjct: 5 FDQLTPDLVLDAVESLGYLSDARVLALNSYENRVYQVGIEDGEPLIAKFYRPDRWSDAAI 64 Query: 76 LEEHAFSQELADEEVPVVPAMRLDNGATLHRHAGFRFAVFRRHGGRAPELDDADTLERLG 135 EEHAFS ELA+ EVPVV + D G +L +GFRFA+F R GGRAPE + D L RLG Sbjct: 65 REEHAFSAELAECEVPVVAPLSRD-GESLFAFSGFRFALFPRRGGRAPEPGNLDQLYRLG 123 Query: 136 RFIGRIHAVGLRSPFQSRPALDIASFGEEPRDWLLAHDFIPMDVATAWRTTVEQALDGVR 195 + +GR+HAVG PF+ R AL + +FG LL +FIP + A+ + A D ++ Sbjct: 124 QLLGRLHAVGATRPFEHREALAVDNFGHASLATLLEGNFIPRSLLPAYESV---ARDLLK 180 Query: 196 RCYERAGEI--RTLRLHGDCHVGNVLWTD 222 R E+ + +RLHGDCH GN+L D Sbjct: 181 RLDALFAEVPYQPIRLHGDCHPGNLLCRD 209 >YPO0014 [R] COG2334 Putative homoserine kinase type II (protein kinase fold) Ype Yersinia pestis Length = 328 Score = 198 bits (503), Expect = 1e-50, Method: Compositional matrix adjust. Identities = 106/221 (47%), Positives = 136/221 (61%), Gaps = 4/221 (1%) Query: 13 ATSFATLSPDTVLDALDGLGLYGDGRLLALNSYENRVYQVGMEDGPPLVAKFYRPLRWSD 72 A +F TLSPD ++DAL+G GL D L ALNSYENRVYQ E+ V KFYRP RWS Sbjct: 5 AFNFQTLSPDLIMDALEGAGLRVDSGLTALNSYENRVYQFMDEESKRYVVKFYRPERWSS 64 Query: 73 EQILEEHAFSQELADEEVPVVPAMRLDNGATLHRHAGFRFAVFRRHGGRAPELDDADTLE 132 EQI EEH FS +LA+ E+PV+ +RL NG TLH H GF FAVF GGR E+D+ D LE Sbjct: 65 EQITEEHQFSLDLAESEIPVIAPLRL-NGKTLHTHCGFFFAVFPSVGGRQYEIDNLDQLE 123 Query: 133 RLGRFIGRIHAVGLRSPFQSRPALDIASFGEEPRDWLLAHDFIPMDVATAWRTTVEQALD 192 +GRF+GRIH S F +RP + I + EPR L D +P+ + + + Sbjct: 124 WVGRFLGRIHQAARNSLFVARPTMGIEEYLTEPRQLLANCDLVPVKQRDKFLAAADLLIT 183 Query: 193 GVRRCYERAGEIRTLRLHGDCHVGNVLWTDAGPXKVSANSS 233 +++ + E + LRLHGDCH GN+LW D GP V + + Sbjct: 184 TIKQYWH--TEWQPLRLHGDCHPGNILWRD-GPMFVDLDDA 221 >VC0035 [R] COG2334 Putative homoserine kinase type II (protein kinase fold) Vch Vibrio cholerae Length = 340 Score = 183 bits (464), Expect = 4e-46, Method: Compositional matrix adjust. Identities = 96/218 (44%), Positives = 132/218 (60%), Gaps = 4/218 (1%) Query: 16 FATLSPDTVLDALDGLGLYGDGRLLALNSYENRVYQVGMEDGPPLVAKFYRPLRWSDEQI 75 F L+PD + AL+ +G+ + L LNSYENRVYQ E+ V KFYRP RW+DEQI Sbjct: 20 FDALTPDLIWYALESIGIRAESGFLPLNSYENRVYQFTDEERRRFVVKFYRPQRWTDEQI 79 Query: 76 LEEHAFSQELADEEVPVVPAMRLDNGATLHRHAGFRFAVFRRHGGRAPELDDADTLERLG 135 EEH F+ EL EE+P+VP +RL NGATLH + G+RFA+F GGR E+D+ + LE +G Sbjct: 80 QEEHDFALELEQEEIPIVPPLRL-NGATLHHYQGYRFALFTSMGGRQYEVDNEEHLEWVG 138 Query: 136 RFIGRIHAVGLRSPFQSRPALDIASFGEEPRDWLLAHDFIPMDVATAWRTTVEQALDGVR 195 RF+GRIH VG PF RP L + + +PR L IP + + ++ + ++ Sbjct: 139 RFLGRIHKVGASKPFLHRPTLSLDEYLHQPRHTLEYSHCIPAHLQRVFFHDLDILIAEIK 198 Query: 196 RCYERAGEIRTLRLHGDCHVGNVLWTDAGPXKVSANSS 233 + + +RLHGDCH GN+LW D GP V + + Sbjct: 199 QHWVPTQP--QIRLHGDCHPGNILWRD-GPMFVDLDDA 233 >STM3996 [R] COG2334 Putative homoserine kinase type II (protein kinase fold) Sty Salmonella typhimurium LT2 Length = 328 Score = 177 bits (449), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 97/222 (43%), Positives = 127/222 (57%), Gaps = 4/222 (1%) Query: 12 DATSFATLSPDTVLDALDGLGLYGDGRLLALNSYENRVYQVGMEDGPPLVAKFYRPLRWS 71 +A +F TL P+T++DAL G+ D L LNSYENRVYQ ED V KFYRP RWS Sbjct: 4 NAFTFQTLHPETIMDALFEQGIMVDSGLTPLNSYENRVYQFQDEDRRRFVVKFYRPERWS 63 Query: 72 DEQILEEHAFSQELADEEVPVVPAMRLDNGATLHRHAGFRFAVFRRHGGRAPELDDADTL 131 +QI EEH F+ EL +EVPV + NG TL H G+ +A+F GGR E D+ D + Sbjct: 64 VDQIREEHQFALELVKDEVPVAAPLAF-NGQTLLAHQGYHYAIFPSVGGRQFEADNIDQM 122 Query: 132 ERLGRFIGRIHAVGLRSPFQSRPALDIASFGEEPRDWLLAHDFIPMDVATAWRTTVEQAL 191 E +GR++GR+H G + PF RP + +A + EPR IP A+ + L Sbjct: 123 EAVGRYLGRLHQTGRKRPFTFRPDIGLAEYLFEPRQVFEDAALIPSGQKAAFLKATDTLL 182 Query: 192 DGVRRCYERAGEIRTLRLHGDCHVGNVLWTDAGPXKVSANSS 233 V C+ + TLRLHGDCH GN+LW D GP V + + Sbjct: 183 SAVTECWR--TDFATLRLHGDCHAGNILWRD-GPLFVDLDDA 221