BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0097.p (245 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1601 [C] COG0508 Pyruvate/2-oxoglutarate dehydrogenase comple... 342 5e-94 XF0869 [C] COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex... 340 2e-93 VC2413 [C] COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex... 334 9e-92 NMA1555 [C] COG0508 Pyruvate/2-oxoglutarate dehydrogenase comple... 330 2e-90 NMB1342 [C] COG0508 Pyruvate/2-oxoglutarate dehydrogenase comple... 329 4e-90 >RSc1601 [C] COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Rso Ralstonia solanacearum Length = 554 Score = 342 bits (877), Expect = 5e-94, Method: Compositional matrix adjust. Identities = 175/243 (72%), Positives = 191/243 (78%), Gaps = 6/243 (2%) Query: 3 PKVFFSLDPIGETELQPLSRIKKISGPNLHRNWVMIPHVTQFDEADVTELEEFRKTSNDA 62 PKV F+ G E +PLSRIKKISG NLHRNWVMIPHVT DEAD+TELE FR N Sbjct: 318 PKVDFT--KFGPVEPKPLSRIKKISGANLHRNWVMIPHVTNNDEADITELEAFRVQMNKE 375 Query: 63 FAKAKSPVKLTMLAFVIKASVSALKKFPAFNASLDEKGENLILKKYYNIGFAADTPNGLV 122 KA VK TMLAFVIKA V ALKKFP FNASLD G+NL+ K+YY+IGFAADTPNGLV Sbjct: 376 HEKAG--VKFTMLAFVIKAVVGALKKFPTFNASLD--GDNLVFKQYYHIGFAADTPNGLV 431 Query: 123 VPVIKNADQKSIGQIATEMGELSAQARDGKLKPADMQGATFTISSLGGIGGTAFTPIINA 182 VPVI++AD+K + IA EM ELS AR+GKLKP MQG F+ISSLGGIGGT FTPIINA Sbjct: 432 VPVIRDADKKGVVDIAREMAELSKAAREGKLKPDQMQGGCFSISSLGGIGGTHFTPIINA 491 Query: 183 PEVAILGLSKSITKPVWDGKQFVPRLMLPTSLSYDHRVIDGAMGARFSAYLADVLGDLRK 242 PEVAILGLS+ KPVWDGKQFVPRL LP SLSYDHRVIDGA ARF+AYLA VL D R+ Sbjct: 492 PEVAILGLSRGYQKPVWDGKQFVPRLTLPLSLSYDHRVIDGAEAARFNAYLAAVLADFRR 551 Query: 243 SLL 245 LL Sbjct: 552 VLL 554 >XF0869 [C] COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Xfa Xylella fastidiosa 9a5c Length = 551 Score = 340 bits (872), Expect = 2e-93, Method: Compositional matrix adjust. Identities = 166/246 (67%), Positives = 194/246 (78%), Gaps = 5/246 (2%) Query: 3 PKVFFSLDPIGETELQPLSRIKKISGPNLHRNWVMIPHVTQFDEADVTELEEFR---KTS 59 P V FS GE E QPLSRIKKISG NL RNW MIPHVTQFD+AD+TELE R Sbjct: 308 PNVDFS--KFGEIETQPLSRIKKISGANLARNWAMIPHVTQFDQADITELEALRVQINKE 365 Query: 60 NDAFAKAKSPVKLTMLAFVIKASVSALKKFPAFNASLDEKGENLILKKYYNIGFAADTPN 119 N A K + +KLT+LAF+IKAS +ALKKFP FNASLD GE L LKKY++IGFAADTPN Sbjct: 366 NAAPNKNGTGIKLTVLAFLIKASAAALKKFPTFNASLDATGETLTLKKYFHIGFAADTPN 425 Query: 120 GLVVPVIKNADQKSIGQIATEMGELSAQARDGKLKPADMQGATFTISSLGGIGGTAFTPI 179 GLVVPVI+N DQK I +IA E +L+ +ARDGKL PADM G F+ISSLGGIGGTAFTPI Sbjct: 426 GLVVPVIRNVDQKGIVEIAQETSDLAKKARDGKLTPADMSGGCFSISSLGGIGGTAFTPI 485 Query: 180 INAPEVAILGLSKSITKPVWDGKQFVPRLMLPTSLSYDHRVIDGAMGARFSAYLADVLGD 239 INAPEVAILG+SKS+ +P+WDG QF P+++LP SLSYDHRVIDGA+ A F+ YL+ +L D Sbjct: 486 INAPEVAILGVSKSLIQPIWDGTQFAPKMLLPLSLSYDHRVIDGALAAHFTTYLSQILAD 545 Query: 240 LRKSLL 245 +R+ LL Sbjct: 546 MRRVLL 551 >VC2413 [C] COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Vch Vibrio cholerae Length = 635 Score = 334 bits (857), Expect = 9e-92, Method: Compositional matrix adjust. Identities = 161/243 (66%), Positives = 194/243 (79%), Gaps = 2/243 (0%) Query: 3 PKVFFSLDPIGETELQPLSRIKKISGPNLHRNWVMIPHVTQFDEADVTELEEFRKTSNDA 62 PKV FS G+TE+QPLSRIKKISG NLHRNWVMIPHVTQ+D AD+TELE+FR+ N Sbjct: 395 PKVDFS--KFGDTEVQPLSRIKKISGANLHRNWVMIPHVTQWDNADITELEKFRQEQNAM 452 Query: 63 FAKAKSPVKLTMLAFVIKASVSALKKFPAFNASLDEKGENLILKKYYNIGFAADTPNGLV 122 AK + +K+T L F++KA+ AL+ FPAFN+SL + GE+LILKKY NIG A DTPNGLV Sbjct: 453 EAKRDTGMKITPLVFIMKAAAKALEAFPAFNSSLSDDGESLILKKYVNIGIAVDTPNGLV 512 Query: 123 VPVIKNADQKSIGQIATEMGELSAQARDGKLKPADMQGATFTISSLGGIGGTAFTPIINA 182 VPV K+ ++K I +++ E+ E+S +AR GKL ADMQG FTISSLGGIGGTAFTPI+NA Sbjct: 513 VPVFKDVNKKGIYELSKELAEVSKKARGGKLTAADMQGGCFTISSLGGIGGTAFTPIVNA 572 Query: 183 PEVAILGLSKSITKPVWDGKQFVPRLMLPTSLSYDHRVIDGAMGARFSAYLADVLGDLRK 242 PEVAILG+SKS KPVW+GK+F PRL LP SLSYDHRVIDGA GARF YL + L D+R+ Sbjct: 573 PEVAILGVSKSEMKPVWNGKEFAPRLQLPLSLSYDHRVIDGAEGARFITYLNECLSDIRR 632 Query: 243 SLL 245 +L Sbjct: 633 LVL 635 >NMA1555 [C] COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes NmA Neisseria meningitidis Z2491 Length = 535 Score = 330 bits (845), Expect = 2e-90, Method: Compositional matrix adjust. Identities = 165/243 (67%), Positives = 194/243 (79%), Gaps = 6/243 (2%) Query: 3 PKVFFSLDPIGETELQPLSRIKKISGPNLHRNWVMIPHVTQFDEADVTELEEFRKTSNDA 62 PKV FS G E++ LSRIKKISG NL RNWV+IPHVT +EAD+TELEEFRK N Sbjct: 299 PKVDFS--KFGNVEVKELSRIKKISGQNLSRNWVVIPHVTVHEEADMTELEEFRKQLNKE 356 Query: 63 FAKAKSPVKLTMLAFVIKASVSALKKFPAFNASLDEKGENLILKKYYNIGFAADTPNGLV 122 + + VKL+ LAF+IKASVSALK FP FNASLD G+NL+LK Y+NIGFAADTPNGLV Sbjct: 357 WER--EGVKLSPLAFIIKASVSALKAFPEFNASLD--GDNLVLKNYFNIGFAADTPNGLV 412 Query: 123 VPVIKNADQKSIGQIATEMGELSAQARDGKLKPADMQGATFTISSLGGIGGTAFTPIINA 182 VPVIK+ DQK + QI+ E+ ELS +AR+GKLKP +MQGA FTISSLGGIGGT FTPI+NA Sbjct: 413 VPVIKDVDQKGLKQISQELTELSKKAREGKLKPQEMQGACFTISSLGGIGGTGFTPIVNA 472 Query: 183 PEVAILGLSKSITKPVWDGKQFVPRLMLPTSLSYDHRVIDGAMGARFSAYLADVLGDLRK 242 PEVAILG+ KS KPVW+GK+F PRLM P SLS+DHRVIDGA G RF+ +LA++L D R+ Sbjct: 473 PEVAILGVCKSQIKPVWNGKEFAPRLMCPLSLSFDHRVIDGAAGMRFTVFLANLLKDFRR 532 Query: 243 SLL 245 L Sbjct: 533 ITL 535 >NMB1342 [C] COG0508 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Nme Neisseria meningitidis MC58 Length = 535 Score = 329 bits (843), Expect = 4e-90, Method: Compositional matrix adjust. Identities = 165/243 (67%), Positives = 193/243 (79%), Gaps = 6/243 (2%) Query: 3 PKVFFSLDPIGETELQPLSRIKKISGPNLHRNWVMIPHVTQFDEADVTELEEFRKTSNDA 62 PKV FS G E++ LSRIKKISG NL RNWV+IPHVT +EAD+TELEEFRK N Sbjct: 299 PKVDFS--KFGNVEVKELSRIKKISGQNLSRNWVVIPHVTVHEEADMTELEEFRKQLNKE 356 Query: 63 FAKAKSPVKLTMLAFVIKASVSALKKFPAFNASLDEKGENLILKKYYNIGFAADTPNGLV 122 + + VKL+ LAF+IKASVSALK FP FNASLD G+NL+LK Y+NIGFAADTPNGLV Sbjct: 357 WER--EGVKLSPLAFIIKASVSALKAFPEFNASLD--GDNLVLKNYFNIGFAADTPNGLV 412 Query: 123 VPVIKNADQKSIGQIATEMGELSAQARDGKLKPADMQGATFTISSLGGIGGTAFTPIINA 182 VPVIK+ DQK + QI+ E+ ELS +AR+GKLKP +MQGA FTISSLGGIGGT FTPI+NA Sbjct: 413 VPVIKDVDQKGLKQISQELTELSKKAREGKLKPQEMQGACFTISSLGGIGGTGFTPIVNA 472 Query: 183 PEVAILGLSKSITKPVWDGKQFVPRLMLPTSLSYDHRVIDGAMGARFSAYLADVLGDLRK 242 PEVAILG+ KS KPVW+GK+F PRLM P SLS+DHRVIDGA G RF+ +LA +L D R+ Sbjct: 473 PEVAILGVCKSQIKPVWNGKEFAPRLMCPLSLSFDHRVIDGAAGMRFTVFLAKLLKDFRR 532 Query: 243 SLL 245 L Sbjct: 533 ITL 535