BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0034.0047.p (421 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Cgl2686 [GEPR] COG0477 Permeases of the major facilitator superf... 129 1e-29 AGc4834 [GEPR] COG0477 Permeases of the major facilitator superf... 126 1e-28 SMc03825 [GEPR] COG0477 Permeases of the major facilitator super... 125 2e-28 PA3573 [GEPR] COG0477 Permeases of the major facilitator superfa... 124 4e-28 VCA0083 [GEPR] COG0477 Permeases of the major facilitator superf... 118 2e-26 >Cgl2686 [GEPR] COG0477 Permeases of the major facilitator superfamily Cgl Corynebacterium glutamicum Length = 398 Score = 129 bits (324), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 111/352 (31%), Positives = 175/352 (49%), Gaps = 17/352 (4%) Query: 38 DLYVPALPQMAIDYGTSAQAIQTSVTGYLIAYAFGQLAFGPLADAWGRRRVLMLGLGLFT 97 D+Y+PA+P +A D GT+A +Q +++ ++ A GQL GPL+D GR+ +L+ G Sbjct: 27 DMYLPAMPGIAEDLGTTAPMVQLTLSSFMAGMAIGQLIIGPLSDQLGRKGLLVAGAVAAL 86 Query: 98 LGCVLTLLAPNLETFVAARVLQGFGIAATNLLAKAIITDSFVGQTLVHAYTYMAIAWGLA 157 + V+ LAP++ V AR++QG G A ++A+AI+ D GQ HA+ + I G+A Sbjct: 87 VASVVCALAPSISVLVIARLVQGLGGGACVVIARAIVPDLERGQKAAHAFALLMIIQGIA 146 Query: 158 PIIAPVIGAHLQEAFGWRSCLVFLLLYSFAMWAI-LWRYRETLAEPVHLHPAT----LLK 212 P++AP+IG L FGWR L L +FA + L + +E+ +PV A +L Sbjct: 147 PVVAPLIGGVLVGPFGWRGIFWALALVNFAQLLVALLQIKES--KPVEERTAAGLGGMLS 204 Query: 213 NARMVLASPVFQSCFLAQGLCYSILLVFNIVGPFMVQNTLRQPPTFFGYLALAIGMMYFL 272 N VL +P F + GL + + + PF++QN + P + + + Sbjct: 205 NYVFVLKNPQFLAYVFTLGLSFGAMFSYISASPFVLQNQMGIPVLLYSIIFGVNAFGLIV 264 Query: 273 GGISNRIHHRRLPSAEQRLRIGARVMTAAAFAMLALALLVGLTVWTLITPVLVMAFCAGA 332 GG+ N RRL RI V+ A+F +L LL+ + I L++ F + Sbjct: 265 GGMVN----RRLLQRIHPHRIMQTVL--ASFTVLCALLLIEVLFINWIPLFLLLLFLIVS 318 Query: 333 MYPTLMAK----GNSIFPHIAGLTSAILGFALLLVSSGMMGLAGFVSIHSLT 380 P +MA G + AG SAILGF + + + L G S +LT Sbjct: 319 HIPMVMANATALGTEVVRSRAGSGSAILGFVQFTMGALVSSLVGLGSDKALT 370 >AGc4834 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 398 Score = 126 bits (316), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 98/333 (29%), Positives = 163/333 (48%), Gaps = 17/333 (5%) Query: 35 LAIDLYVPALPQMAIDYGTSAQAIQTSVTGYLIAYAFGQLAFGPLADAWGRRRVLMLGLG 94 +++ +Y PA+P++ + T+ AI+ S++ Y +A QL GP +DA+GRRR ++ L Sbjct: 25 ISMAIYTPAMPELTRVFATNESAIKLSLSLYFAGFALAQLLAGPASDAFGRRRASLVFLS 84 Query: 95 LFTLGCVLTLLAPNLETFVAARVLQGFGIAATNLLAKAIITDSFVGQTLVHAYTYMAIAW 154 +F G +L + AP +E + AR++QG G + +A+AI+ D F G + I Sbjct: 85 VFLGGGLLAIFAPTIEVLLLARLIQGIGASVGMTVARAIVRDQFTGAEASSIMNLIGIML 144 Query: 155 GLAPIIAPVIGAHLQEAFGWRSCLVFLLLYSF---AMWAILWRYRE-TLAEPVHLHPATL 210 + P + P IG AFGW+S VF L+ A+++++ RE T+ + + P L Sbjct: 145 AVGPALGPTIGGLSLAAFGWKS--VFFLMAGLGAAAIFSVVIFLRETTVPDKSLIRPRRL 202 Query: 211 LKNARMVLASPVFQSCFLAQGLCYSILLVFNIVGPFMVQNTLRQPPTFFGYLALAIGMM- 269 L +L P F L G L + F++ NT+ PT FG IGM+ Sbjct: 203 LSAYGNLLTEPRFLLAALVLGGSIGALYAQATMLTFILINTVGMTPTAFG-----IGMLM 257 Query: 270 ----YFLGGISNRIHHRRLPSAEQRLRIGARVMTAAAFAMLALALLVGLTVWTLITPVLV 325 YF G I+ R RL + + +G +L L+ + ++++ PV V Sbjct: 258 QTGAYFFGSIALRYIAPRL-GDRRSVMLGLCFSGTGGLLILLSVFLIPPSFFSIMGPVAV 316 Query: 326 MAFCAGAMYPTLMAKGNSIFPHIAGLTSAILGF 358 + P+++ + FPHIAG SA++GF Sbjct: 317 ATVGIALLTPSMVTAALAPFPHIAGSASAMMGF 349 >SMc03825 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 412 Score = 125 bits (315), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 105/350 (30%), Positives = 176/350 (50%), Gaps = 30/350 (8%) Query: 25 LICAFASA-GQLAIDLYVPALPQMAIDYGTSAQAIQTSVTGYLIAYAFGQLAFGPLADAW 83 +I AF A G +++ LY PA+P++ + +S AI+ +++ Y +AF QL G L+D Sbjct: 12 IIGAFLVALGPISMALYTPAMPELVRAFASSEAAIKMTLSLYFGGFAFAQLVSGTLSDVI 71 Query: 84 GRRRVLMLGLGLFTLGCVLTLLAPNLETFVAARVLQGFGIAATNLLAKAIITDSFVGQTL 143 GRRR ++ + ++ G ++ AP++ +A R++QG G + +A+AI+ D F G T Sbjct: 72 GRRRTTLIFMAIYLAGSLMAAFAPSIPVLLAGRLVQGIGASVGMTVARAIVRDQFTGTTA 131 Query: 144 VHAYTYMAIAWGLAPIIAPVIGAHLQEAFGWRSCLVFLLLYSFAMWA--ILWRYRETLAE 201 + + L P ++P +G+ FGW+S +FLL+ FA+ A I+ + Sbjct: 132 ARIMNMIGMMLALGPAVSPTLGSIALGLFGWQS--IFLLMVGFALMACFIVQLFMAETTT 189 Query: 202 PV----HLHP-----ATLLKNARMVLASPVFQSCFLAQGLCYSILLVFNIVGPFMVQNTL 252 P H P L+++ R V ++ V A G Y+ + + PF++ + + Sbjct: 190 PDRSKGHFRPILAAYGELMRDGRFVSSTLVIAG---AVGALYA----WATMLPFVLISQV 242 Query: 253 RQPPTFFGYLALAIGMMYFLGGISNRIHHRRL-PSA---EQRLRIGARVMTAAAFAMLAL 308 PT FG L ++F G ++ R+ RR P A IGA + A AF M AL Sbjct: 243 GLTPTEFGIGMLMQSGLFFSGTVTMRLMMRRFTPQALVPAGLFFIGAASL-ALAFTMHAL 301 Query: 309 ALLVGLTVWTLITPVLVMAFCAGAMYPTLMAKGNSIFPHIAGLTSAILGF 358 T +++TP+ + AF + P +M + FPHIAG SA++GF Sbjct: 302 E----PTFLSVMTPIGIYAFGIAFVMPYMMTAAMAPFPHIAGTASAMMGF 347 >PA3573 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 392 Score = 124 bits (311), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 103/373 (27%), Positives = 180/373 (48%), Gaps = 7/373 (1%) Query: 22 LLFLICAFASAGQLAIDLYVPALPQMAIDYGTSAQAIQTSVTGYLIAYAFGQLAFGPLAD 81 +L ++ A ++ G LAID Y+P+ P +A + T + +Q S+ Y + GQL +GP+AD Sbjct: 5 ILLILGALSAFGPLAIDFYLPSFPTLAKAFATDVEHVQLSLAAYFAGLSIGQLLYGPVAD 64 Query: 82 AWGRRRVLMLGLGLFTLGCVLTLLAPNLETFVAARVLQGFGIAATNLLAKAIITDSFVGQ 141 +GRR L++G+ +FTL LAP+LE +AAR +Q G A ++++A++ D Sbjct: 65 RYGRRLPLLVGVSIFTLASAACALAPSLEWLIAARFVQALGGCAGMVISRAVVRDLCDPI 124 Query: 142 TLVHAYTYMAIAWGLAPIIAPVIGAHLQEAFGWRSCLVFLLLYS--FAMWAILWRYRETL 199 A++ + + GLAPI+APV G L + GW+S V L L++ + LW Sbjct: 125 GAAKAFSQLMLVMGLAPILAPVAGGLLLDWQGWQSIFVCLTLFAALAGLGVALWLPETIP 184 Query: 200 AEPVHLHPATLLKNARMVLASPVFQSCFLAQGLCYSILLVFNIVGPFMVQNTLRQPPTFF 259 A+ + L R + A +F + L+ G+ + + + P++ P + Sbjct: 185 ADGERPPLSGALGQYRRLFADRLFLAYGLSGGVAMAGMFAYIAGSPYVFIQLYGIPAEHY 244 Query: 260 GYL--ALAIGMMYFLGGISNRIHHRRLPSAEQRLRIGARVMTAAAFAMLALALLVGLTVW 317 G+L + A G + + ++ R+ R P+ R I + A A+L +A L T+W Sbjct: 245 GWLFGSNAAGFI-VMAQVNARLLRYRGPAFWLRRIIWGYL--ACGLALLGIASLQPATLW 301 Query: 318 TLITPVLVMAFCAGAMYPTLMAKGNSIFPHIAGLTSAILGFALLLVSSGMMGLAGFVSIH 377 L+ P+ G + P A + AG SA++G V++G L G + Sbjct: 302 PLLVPLFGCVASLGCIIPNASACAMAGQGQHAGSASALMGSLQFSVAAGASALVGVLHDG 361 Query: 378 SLTPLAVFFCIVG 390 + P+ + + G Sbjct: 362 TAIPMTLVIAVCG 374 >VCA0083 [GEPR] COG0477 Permeases of the major facilitator superfamily Vch Vibrio cholerae Length = 403 Score = 118 bits (296), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 115/411 (27%), Positives = 196/411 (47%), Gaps = 43/411 (10%) Query: 19 PKFLLFLICAFASAGQLAIDLYVPALPQMAIDYGTSAQAIQTSVTGYLIAYAFGQLAFGP 78 P L +I A GQ+ + +Y+P+LP ++ D + Q VT +L+ + QL +G Sbjct: 13 PMLLAMMIIA---TGQVGVSIYLPSLPLISRDLQVDQASAQMLVTLFLLGFGGSQLFYGA 69 Query: 79 LADAWGRRRVLMLGLGLFTLGCVL-TLLAPNLETFVAARVLQGFGIAATNLLAKAIITDS 137 L+DA GRR +LG G++ LG VL +++ + + R+LQG G + ++L ++++ DS Sbjct: 70 LSDAVGRRPTFLLGQGIYLLGTVLCVMMSDHFQALEFGRLLQGLGAGSASVLGRSVLRDS 129 Query: 138 FVGQTLVHAYTYMAIAWGLAPIIAPVIGAHLQEAFGWRSCLVFLLLYSFAMWAI-LWRYR 196 + G L A +Y++I + PIIAPV+G L W+S +F+LLY A++ + L Sbjct: 130 YDGFHLTKALSYLSITASIMPIIAPVLGGWLAYHLSWQSVFIFVLLYIGAIFTLGLMILP 189 Query: 197 ETLAEP--------VHLHPATLLKNARMVLASPVFQSCFLAQGLCYSILLVFNIVGPFMV 248 ETL P + ++ A LL N ++ ++ +LA + SIL PF++ Sbjct: 190 ETLPYPKRRVQWRGIVINYAKLLTNQQVTSSASYNWLSYLASLVTLSIL-------PFLL 242 Query: 249 QNTLRQPPTFFGYLALAIGMMYFLGGISNRIHHRRLPSAEQRLRIGARVMTAAAFAMLAL 308 Q L +G + LG + + R S Q L +M A + Sbjct: 243 QKQLGMTAADYGSTLIIPSSGLLLGSVLVNMLTSRF-SVRQLLGCAISLMVFAGLWL--- 298 Query: 309 ALLVGLTVWTLITPVLVMAFCAGAMYPTLMAKGNSIFPHI--AGLTSAILGFALLLVSSG 366 LL +V+ LI ++ G +P +A + PH AG SA+ G S Sbjct: 299 -LLTEFSVFNLIWAFTWLSIAQGISFP--LATTLLLSPHKSQAGAVSALSG-------SI 348 Query: 367 MMGLAGFVS-------IHSLTPLAVFFCIVGLTVIAMVGKLLQHLQVPAAA 410 MG+AG + + S + VF+ +VG+T+++++ + P+AA Sbjct: 349 QMGIAGLLGGYLVEHWVTSQNAMGVFYILVGITMLSVLIATKKAHSQPSAA 399