BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0033.0102.p (342 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1080 [GEPR] COG0477 Permeases of the major facilitator superf... 550 e-156 RSp0834 [GEPR] COG0477 Permeases of the major facilitator superf... 368 e-101 YPO0577 [GEPR] COG0477 Permeases of the major facilitator superf... 329 5e-90 STM3134 [GEPR] COG0477 Permeases of the major facilitator superf... 327 2e-89 exuT [GEPR] COG0477 Permeases of the major facilitator superfami... 326 4e-89 >RSc1080 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 432 Score = 550 bits (1418), Expect = e-156, Method: Compositional matrix adjust. Identities = 279/333 (83%), Positives = 301/333 (90%) Query: 4 VLHAGATGWLSLAGLRALMGLTEAAAIPSGMKAVAEWFPDKEKSVAVGWFNSGTSLGAML 63 LHAGA+GWLSLA R LMGLTEAAAIPSGMKAVAEWFPDKEKSVAVG+FN+GTSLGA+L Sbjct: 90 CLHAGASGWLSLASFRGLMGLTEAAAIPSGMKAVAEWFPDKEKSVAVGYFNAGTSLGALL 149 Query: 64 APPLVIFLQLRYGWQSAFVVTGVLGFAWAALWFAFYRSPRDHAALSETERNTIVGGQQRP 123 APPLV+FL LRYGWQSAFVVTG LGF WAALW+ FYRSPR+HA LS TE + I+GGQ R Sbjct: 150 APPLVVFLSLRYGWQSAFVVTGALGFVWAALWYGFYRSPREHAKLSATEHDRIIGGQIRS 209 Query: 124 VGAVRGKRPVKDVVTSRRFWAIALARFFAEPAWQTFSFWIPLYFVNERHLDLKSIAMFAW 183 GA RGKRPV++VVTSRRFWAIAL RFFAEPAWQTFSFWIPLY + RH+DLK IA+FAW Sbjct: 210 AGAARGKRPVREVVTSRRFWAIALPRFFAEPAWQTFSFWIPLYLSSARHMDLKEIALFAW 269 Query: 184 LPFLAADLGGLAGGYLSPLLMNRFKVPLIWSRVSGVVLGAVMMIGPACVGLVASPYTAIA 243 LPFLAADLGGL GGYLSP M F+VPLIWSRV GVVLGA +MIGPAC+GLVASPY AIA Sbjct: 270 LPFLAADLGGLLGGYLSPFFMKFFRVPLIWSRVCGVVLGAFLMIGPACIGLVASPYQAIA 329 Query: 244 LFCVGGFAHQMISGLVNTLSADVFDPEEVGTASGFAGMSAWIGGLGFSLLVGALADTVGY 303 LFCVGGFAHQMIS LVNTLSADVFDPEEVGTASGFAGM+AWIGGLGFSL+VGALADTVGY Sbjct: 330 LFCVGGFAHQMISTLVNTLSADVFDPEEVGTASGFAGMAAWIGGLGFSLMVGALADTVGY 389 Query: 304 GPLFGMLGAFDLIGAVLLIILIRGQSNDERAAR 336 GPLFG+LGAFDLIGA LLI+LIRGQS +ERAAR Sbjct: 390 GPLFGLLGAFDLIGATLLILLIRGQSQEERAAR 422 >RSp0834 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 435 Score = 368 bits (944), Expect = e-101, Method: Compositional matrix adjust. Identities = 181/324 (55%), Positives = 229/324 (70%), Gaps = 1/324 (0%) Query: 4 VLHAGATGWLSLAGLRALMGLTEAAAIPSGMKAVAEWFPDKEKSVAVGWFNSGTSLGAML 63 +LH+ A W+SLA RA++G+TEAA PS ++A +EWFP KE+S+A GWFN G+S+GA++ Sbjct: 90 ILHSTAGNWVSLAVFRAMLGVTEAAGFPSALRATSEWFPAKERSIATGWFNIGSSVGALV 149 Query: 64 APPLVIFLQLRYGWQSAFVVTGVLGFAWAALWFAFYRSPRDHAALSETERNTIVGGQQRP 123 APPLV++ L W+ AF V GVLG W+ALWF YR P H LS E I GQ+ P Sbjct: 150 APPLVVWCILHGNWRFAFAVIGVLGLVWSALWFMLYRVPARHPRLSAEEHAYIRAGQETP 209 Query: 124 VGAVRGKRPV-KDVVTSRRFWAIALARFFAEPAWQTFSFWIPLYFVNERHLDLKSIAMFA 182 +P +++++ RRFW IA+ RF EPAWQTF+FWIPLY ERH++LK IAMFA Sbjct: 210 APGADAVKPSWREIMSGRRFWGIAIPRFLTEPAWQTFNFWIPLYMATERHMNLKEIAMFA 269 Query: 183 WLPFLAADLGGLAGGYLSPLLMNRFKVPLIWSRVSGVVLGAVMMIGPACVGLVASPYTAI 242 WLPFLAAD+G + GGYL+P RF LI SR +V GAV MIGPAC+GL SPYTAI Sbjct: 270 WLPFLAADVGCVLGGYLAPWYQKRFSTSLITSRKMVMVTGAVCMIGPACIGLATSPYTAI 329 Query: 243 ALFCVGGFAHQMISGLVNTLSADVFDPEEVGTASGFAGMSAWIGGLGFSLLVGALADTVG 302 ALFCVGGFAHQ +SG + TL++DVF EVGTA G AGMS ++GG FSL VG LA T+G Sbjct: 330 ALFCVGGFAHQTLSGALYTLTSDVFGKHEVGTAVGLAGMSGFLGGTLFSLAVGTLASTIG 389 Query: 303 YGPLFGMLGAFDLIGAVLLIILIR 326 Y PLF L FD+ A+++ ++R Sbjct: 390 YNPLFAALALFDIAAAIVMWNVLR 413 >YPO0577 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 434 Score = 329 bits (844), Expect = 5e-90, Method: Compositional matrix adjust. Identities = 161/325 (49%), Positives = 217/325 (66%), Gaps = 1/325 (0%) Query: 9 ATGWLSLAGLRALMGLTEAAAIPSGMKAVAEWFPDKEKSVAVGWFNSGTSLGAMLAPPLV 68 A+ W LA R +G+ EAA IP+G+KA +EWFP KE+S+AVG+FN G+S+G M+APPLV Sbjct: 96 ASSWGGLAIARGAVGMAEAAMIPAGLKASSEWFPAKERSIAVGYFNVGSSIGGMIAPPLV 155 Query: 69 IFLQLRYGWQSAFVVTGVLGFAWAALWFAFYRSPRDHAALSETERNTIVGGQQRPVGAVR 128 ++ + + WQ AF++TGVL WA W Y+ P+D LS+ ER I+ GQ+ Sbjct: 156 VWAIVMHSWQMAFIITGVLSLIWAIAWLILYKHPKDQKRLSDEEREYILSGQEAQHSTAN 215 Query: 129 GKR-PVKDVVTSRRFWAIALARFFAEPAWQTFSFWIPLYFVNERHLDLKSIAMFAWLPFL 187 K+ ++ +R+FW IA+ RF AEPAW TF+ WIPL+ +LK IAMFAW+P L Sbjct: 216 AKKMSAMQIIRNRQFWGIAIPRFLAEPAWGTFNAWIPLFMFKAYGFNLKEIAMFAWMPML 275 Query: 188 AADLGGLAGGYLSPLLMNRFKVPLIWSRVSGVVLGAVMMIGPACVGLVASPYTAIALFCV 247 AD+G + GGYL PL FKV LI SR V +G V+MIGP +GL SPY AIAL C+ Sbjct: 276 FADVGCILGGYLPPLFQKYFKVNLIVSRKLVVTMGGVLMIGPGTIGLFTSPYAAIALLCI 335 Query: 248 GGFAHQMISGLVNTLSADVFDPEEVGTASGFAGMSAWIGGLGFSLLVGALADTVGYGPLF 307 GGFAHQ +SG + TLS+DVF EV TA+G GM+AW F+L+VGALADT+G+ PLF Sbjct: 336 GGFAHQALSGALITLSSDVFGRNEVATANGLTGMAAWTASTLFALVVGALADTMGFSPLF 395 Query: 308 GMLGAFDLIGAVLLIILIRGQSNDE 332 L FDL+ V++ +++ ++ DE Sbjct: 396 AALAVFDLLAVVVIWTVLQDRTADE 420 >STM3134 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 434 Score = 327 bits (838), Expect = 2e-89, Method: Compositional matrix adjust. Identities = 170/341 (49%), Positives = 221/341 (64%), Gaps = 10/341 (2%) Query: 6 HAGATGWLSLAGLRALMGLTEAAAIPSGMKAVAEWFPDKEKSVAVGWFNSGTSLGAMLAP 65 HA A GW+SLA LR LMGLTEA+AIP+G+KA AEWFP KE+ +A G FN GTS+GAMLAP Sbjct: 91 HALAGGWISLAFLRGLMGLTEASAIPAGIKASAEWFPTKERGIAGGLFNIGTSIGAMLAP 150 Query: 66 PLVIFLQLRY-----GWQSAFVVTGVLGFAWAALWFAFYRSPRDHAALSETERNTIVGGQ 120 PLV++ L + G + AFV+TG +G +A WF Y SP H ++ E I GQ Sbjct: 151 PLVVWAMLTFADSGIGTEMAFVITGGIGVLFAITWFLIYNSPNKHPWITHKELRYIEDGQ 210 Query: 121 QRPVGAVRGKRPVKDVVTSRRFWAIALARFFAEPAWQTFSFWIPLYFVNERHLDLKSIAM 180 + + K VK++V R FWA+A+ RF A+PAW T SFW+PLY +N HL LK IAM Sbjct: 211 ESYLQDDNKKPAVKEIVKKRNFWALAITRFLADPAWGTLSFWMPLYLINVMHLPLKEIAM 270 Query: 181 FAWLPFLAADLGGLAGGYLSPLLMNRFKVPLIWSRVSGVVLGAVMMIGPACVGLVASPYT 240 FAWLPFLAAD G +AGG+L+ M + + I +R +GAV+MI V + +PY Sbjct: 271 FAWLPFLAADFGCVAGGFLAKFFMEKMHMTTINARRCSFTIGAVLMISIGFVSITTNPYV 330 Query: 241 AIALFCVGGFAHQMISGLVNTLSADVFDPEEVGTASGFAGMSAWIGGLGFSLLVGALADT 300 AIAL +GGFAHQ +S +V T+SAD+F EV T +G AG +AW+G L F+L +GAL Sbjct: 331 AIALMSIGGFAHQTLSTVVITMSADLFKKNEVATVAGLAGSAAWMGQLSFNLFMGALVAI 390 Query: 301 VGYGPLFGMLGAFDLIGAVLLIILIRGQSNDERAARTPPRT 341 +GYGP F L FD+IGA++L +LI+ PP T Sbjct: 391 IGYGPFFIALSLFDIIGAIILWVLIKDPEKHH-----PPMT 426 >exuT [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 472 Score = 326 bits (836), Expect = 4e-89, Method: Compositional matrix adjust. Identities = 163/314 (51%), Positives = 216/314 (68%), Gaps = 3/314 (0%) Query: 26 EAAAIPSGMKAVAEWFPDKEKSVAVGWFNSGTSLGAMLAPPLVIFLQLRYGWQSAFVVTG 85 EAA IP+G+KA +EWFP KE+S+AVG+FN G+S+GAM+APPLV++ + + WQ AF+++G Sbjct: 152 EAAMIPAGLKASSEWFPAKERSIAVGYFNVGSSIGAMIAPPLVVWAIVMHSWQMAFIISG 211 Query: 86 VLGFAWAALWFAFYRSPRDHAALSETERNTIVGGQ--QRPVGAVRGKRPVKDVVTSRRFW 143 L F WA W FY+ PRD L++ ER+ I+ GQ Q V + K V ++ +R+FW Sbjct: 212 ALSFIWAMAWLIFYKHPRDQKHLTDEERDYIINGQEAQHQVSTAK-KMSVGQILRNRQFW 270 Query: 144 AIALARFFAEPAWQTFSFWIPLYFVNERHLDLKSIAMFAWLPFLAADLGGLAGGYLSPLL 203 IAL RF AEPAW TF+ WIPL+ +LK IAMFAW+P L ADLG + GGYL PL Sbjct: 271 GIALPRFLAEPAWGTFNAWIPLFMFKVYGFNLKEIAMFAWMPMLFADLGCILGGYLPPLF 330 Query: 204 MNRFKVPLIWSRVSGVVLGAVMMIGPACVGLVASPYTAIALFCVGGFAHQMISGLVNTLS 263 F V LI SR V LGAV+MIGP +GL +PY AI L C+GGFAHQ +SG + TLS Sbjct: 331 QRWFGVNLIVSRKMVVTLGAVLMIGPGMIGLFTNPYVAIMLLCIGGFAHQALSGALITLS 390 Query: 264 ADVFDPEEVGTASGFAGMSAWIGGLGFSLLVGALADTVGYGPLFGMLGAFDLIGAVLLII 323 +DVF EV TA+G GMSAW+ F+L+VGALADT+G+ PLF +L FDL+GA+++ Sbjct: 391 SDVFGRNEVATANGLTGMSAWLASTLFALVVGALADTIGFSPLFAVLAVFDLLGALVIWT 450 Query: 324 LIRGQSNDERAART 337 +++ + E A T Sbjct: 451 VLQNKPAIEVAQET 464