BLASTP 2.2.21 [Jun-14-2009]

Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0033.0093.p         (203 letters)

Database: COGmodified 
           192,987 sequences; 59,019,183 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

RSp0233 [R] COG3618 Predicted metal-dependent hydrolase of the T...   117   1e-26
Cj0556 [R] COG3618 Predicted metal-dependent hydrolase of the TI...    80   3e-15
YPO1933 [R] COG3618 Predicted metal-dependent hydrolase of the T...    67   2e-11

>RSp0233 [R] COG3618 Predicted metal-dependent hydrolase of the TIM-barrel
           fold Rso Ralstonia solanacearum
          Length = 302

 Score =  117 bits (294), Expect = 1e-26,   Method: Compositional matrix adjust.
 Identities = 54/74 (72%), Positives = 64/74 (86%)

Query: 14  IDTHAHVFARGLPMADVRRYTPAYDVTVEEYLARLDAHGMSHGVLVQPSFLGCDNSYLLQ 73
           IDTHAHVF RGLP+A  RRY P+YD T+  YLA+LDAHG+SHGVL+QPSFLG DNSYLL 
Sbjct: 38  IDTHAHVFKRGLPLAGARRYAPSYDATLPAYLAQLDAHGLSHGVLIQPSFLGGDNSYLLA 97

Query: 74  AIARAPQRLRGIAL 87
           A+ +APQRLRG+A+
Sbjct: 98  ALRQAPQRLRGVAV 111



 Score = 96.7 bits (239), Expect = 3e-20,   Method: Compositional matrix adjust.
 Identities = 56/116 (48%), Positives = 73/116 (62%), Gaps = 7/116 (6%)

Query: 89  RVDAALGVDDPGFRYLLSTGPSRQVWVKLSAQYRNGGSEGDFGPDRLLWGSDWPXLLRQH 148
           R D AL V+DPGF  LL+ G +R+VWVK+S  YRNG    D G    +  +  P L +  
Sbjct: 193 RPDPALSVEDPGFAALLAAGRTRRVWVKVSGAYRNG----DAGRGEAIALAAMPRL-KDA 247

Query: 149 FGPDRLLWGSDWPHTQHESMTSYADSWRRF-ESLVSDEADRRCITGETAAQLFQFS 203
            G DRL+WGSDWPHTQ+ES   Y DS R F ++L+ D  DR  +  ET A+LF+F+
Sbjct: 248 LGTDRLVWGSDWPHTQYESRIGY-DSARAFADTLLPDAGDRHQVLVETPARLFRFA 302


>Cj0556 [R] COG3618 Predicted metal-dependent hydrolase of the TIM-barrel
          fold Cje Campylobacter jejuni
          Length = 265

 Score = 79.7 bits (195), Expect = 3e-15,   Method: Compositional matrix adjust.
 Identities = 37/87 (42%), Positives = 55/87 (63%), Gaps = 3/87 (3%)

Query: 12 LRIDTHAHVFARGLPMADVRRYTPAYDVTVEEYLARLDAHGMSHGVLVQPSFLGCDNSYL 71
          ++IDTHAH+F + L      RY P YD + ++Y A LD +  + GVLVQPSFLG DN +L
Sbjct: 1  MKIDTHAHIFLKKLNTVANARYKPDYDASFKDYKANLDHYDFNKGVLVQPSFLGIDNEFL 60

Query: 72 LQAIARAPQRLRGIALXRVDAALGVDD 98
          LQ+I +  + ++ I +  VD  +  D+
Sbjct: 61 LQSIEK-DENIKAIVV--VDENIKFDE 84


>YPO1933 [R] COG3618 Predicted metal-dependent hydrolase of the TIM-barrel
           fold Ype Yersinia pestis
          Length = 289

 Score = 67.4 bits (163), Expect = 2e-11,   Method: Compositional matrix adjust.
 Identities = 40/90 (44%), Positives = 53/90 (58%), Gaps = 3/90 (3%)

Query: 5   AVLSTPALRIDTHAHVFA-RGL-PMADVRRYTPAYDVTVEEYLARLDAHGMSHGVLVQPS 62
           ++ + P    D+HAHV + R + PM   R YTP      E+YL+ L A GMS GVLVQ S
Sbjct: 18  SIFALPEDACDSHAHVISPRAIYPMVAERSYTPP-PAPEEKYLSMLAATGMSRGVLVQIS 76

Query: 63  FLGCDNSYLLQAIARAPQRLRGIALXRVDA 92
             G DN Y+LQ + R P+ LRG+A+   D 
Sbjct: 77  VYGSDNRYMLQVLKRHPEYLRGVAVVTEDV 106