BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0033.0092.p (422 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp0234 [GEPR] COG0477 Permeases of the major facilitator superf... 565 e-161 YPO1932 [GEPR] COG0477 Permeases of the major facilitator superf... 424 e-118 PA2114 [GEPR] COG0477 Permeases of the major facilitator superfa... 414 e-115 PM0835 [GEPR] COG0477 Permeases of the major facilitator superfa... 182 1e-45 RSp0797 [GEPR] COG0477 Permeases of the major facilitator superf... 176 1e-43 >RSp0234 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 416 Score = 565 bits (1456), Expect = e-161, Method: Compositional matrix adjust. Identities = 289/422 (68%), Positives = 341/422 (80%), Gaps = 15/422 (3%) Query: 1 MFSWYRQVTAKERKTFWACFSGWALDALDVQMFSLAIPALIAAFSLSKADAGMISGATLV 60 MF W+++++A E++TFWACF GWALDALDVQMFSL IP +IAA+ + K +AG++SG TLV Sbjct: 1 MFGWFKEISAGEKRTFWACFGGWALDALDVQMFSLVIPTIIAAWHIGKTEAGLVSGITLV 60 Query: 61 ASAIGGWFAGALSDRYGRVKTLQITIIWFSFFTFLSAFAQSYPQLLVLKALQGFGFGGEW 120 ASA+GGW AGA++DR GRV+TLQIT+ WFS TF SAFAQ++ Q L LKA+QGFGFGGEW Sbjct: 61 ASALGGWIAGAMTDRLGRVRTLQITVAWFSLATFASAFAQNFEQFLALKAVQGFGFGGEW 120 Query: 121 AAGAVLMAETIRAEHRGRAMGTVQSAWAVGWGGAVLLFSVLFTMLPQEMAWRVMFVIGLL 180 AAGAVLMAE+IRA HRG+AMGTVQSAWAVGWG AVLL+++ ++++ ++AWRVMF G+L Sbjct: 121 AAGAVLMAESIRASHRGKAMGTVQSAWAVGWGAAVLLYALTYSLVEPDLAWRVMFAAGVL 180 Query: 181 PALLVVYVRRSVSETDAFLAGRKAATSKPAAST----LLGIFRPDVLRLTLIGSLLGVGA 236 PALL++Y+RR V E AG KA LL IFRP VLR+TLIG+LLGVGA Sbjct: 181 PALLIIYIRRGVQEPAP--AGAKAEAGPDGMPVSRFPLLDIFRPRVLRMTLIGALLGVGA 238 Query: 237 HGGYYALMTWLPTYLKTEKHLSVLSTGGYLAVIIIAFWCGCIASAQLLDRIGRRRTVASF 296 HGGYYALMTWLPTYLKTE+HLSVL TGGYLAVII AFWCGC+ASA LLD IGRR + F Sbjct: 239 HGGYYALMTWLPTYLKTERHLSVLGTGGYLAVIIFAFWCGCVASAWLLDVIGRRGNILLF 298 Query: 297 ALCCVATVLCYIFLPLTDTQMLICGFPLGFFAAGIPASLGALFNELYPSGIRGTGVGFCY 356 + CCV TVL Y+ +PL+D ML+ GFPLGFFAAGIPAS+GALFNELYP G+RGTGVGFCY Sbjct: 299 SCCCVVTVLVYLLVPLSDGAMLVLGFPLGFFAAGIPASMGALFNELYPHGVRGTGVGFCY 358 Query: 357 NFGRVASAGFPVLVGHMSDSMPLGQAIGMRAFKSLGGIDAAIAYSLVVIAVLMLPETKGR 416 NFGRV SA FPVLVG MS SM LG AI GIDAAIAYS+V +AVLMLPET+GR Sbjct: 359 NFGRVVSAAFPVLVGKMSASMSLGTAI---------GIDAAIAYSIVAVAVLMLPETRGR 409 Query: 417 QM 418 + Sbjct: 410 DL 411 >YPO1932 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 409 Score = 424 bits (1090), Expect = e-118, Method: Compositional matrix adjust. Identities = 214/416 (51%), Positives = 283/416 (68%), Gaps = 9/416 (2%) Query: 4 WYRQVTAKERKTFWACFSGWALDALDVQMFSLAIPALIAAFSLSKADAGMISGATLVASA 63 W+ + ERKTF A F GWALDALD +F+ I L+A + + AGM+S TL+ SA Sbjct: 3 WFSDLNQTERKTFIAAFGGWALDALDFMVFTFVIATLMALWQIDAGQAGMLSTVTLLFSA 62 Query: 64 IGGWFAGALSDRYGRVKTLQITIIWFSFFTFLSAFAQSYPQLLVLKALQGFGFGGEWAAG 123 IGGW AG L+DRYGRV+ LQITI+WFS T L FAQ++ + +L+ALQG GFGGEWA G Sbjct: 63 IGGWGAGILADRYGRVRILQITILWFSLCTVLIGFAQNFEHVFILRALQGLGFGGEWAVG 122 Query: 124 AVLMAETIRAEHRGRAMGTVQSAWAVGWGGAVLLFSVLFTMLPQEMAWRVMFVIGLLPAL 183 +VLM E +RAEHRG+A+GTVQS WA+GWG A LL++++F++L +E AWR +F IG+LPAL Sbjct: 123 SVLMGEIVRAEHRGKAVGTVQSGWAIGWGAAALLYTLMFSVLSEEWAWRALFWIGVLPAL 182 Query: 184 LVVYVRRSVSETDAFLAGRKAATSKPAASTLLGIFRPDVLRLTLIGSLLGVGAHGGYYAL 243 LV+Y+R++V E FL R +K + IF P +L+ T++ SLL G GGYYA+ Sbjct: 183 LVLYIRKNVPEPALFLKSRHEQQAKDRRVSSFAIFSPALLKTTVLASLLCTGVQGGYYAI 242 Query: 244 MTWLPTYLKTEKHLSVLSTGGYLAVIIIAFWCGCIASAQLLDRIGRRRTVASFALCCVAT 303 TWLPT+LK E++LSV+ TGGYL VII + G I A L D++GRR + F+L T Sbjct: 243 TTWLPTFLKLERNLSVIGTGGYLMVIIFGSFVGYICGAYLTDKLGRRANLIIFSLLSCIT 302 Query: 304 VLCYIFLPLTDTQMLICGFPLGFFAAGIPASLGALFNELYPSGIRGTGVGFCYNFGRVAS 363 + Y L LT+TQML+ GFPLGF A+GI + +GA EL+PS +R TG GF Y+FGR Sbjct: 303 IFAYTQLTLTNTQMLVLGFPLGFSASGIFSGMGAFLTELFPSAVRATGQGFTYSFGRAVG 362 Query: 364 AGFPVLVGHMSDSMPLGQAIGMRAFKSLGGIDAAIAYSLVVIAVLMLPETKGRQME 419 A FP LVG++S S L AI G+ A AY +V++ L+LPETK +Q+E Sbjct: 363 ALFPGLVGYLSQSSSLAFAI---------GVFAGSAYCIVLVMSLLLPETKNKQLE 409 >PA2114 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 423 Score = 414 bits (1063), Expect = e-115, Method: Compositional matrix adjust. Identities = 211/418 (50%), Positives = 282/418 (67%), Gaps = 10/418 (2%) Query: 2 FSWYRQVTAKERKTFWACFSGWALDALDVQMFSLAIPALIAAFSLSKADAGMISGATLVA 61 F WYR + +ER+ FW+C G+ LD +D QM S IP LIA + + +AG I TL+A Sbjct: 15 FGWYRALDKQERRAFWSCKIGYGLDGMDTQMLSFVIPTLIALWGIGTGEAGFIHTMTLLA 74 Query: 62 SAIGGWFAGALSDRYGRVKTLQITIIWFSFFTFLSAFAQSYPQLLVLKALQGFGFGGEWA 121 SA GGW AG LSDR GRV TLQ+T++WF+FFTFL AQ+Y QLLV + L GFGFGGEW Sbjct: 75 SAAGGWIAGILSDRIGRVLTLQLTVLWFAFFTFLCGLAQNYEQLLVARTLMGFGFGGEWT 134 Query: 122 AGAVLMAETIRAEHRGRAMGTVQSAWAVGWGGAVLLFSVLFTMLPQEMAWRVMFVIGLLP 181 AGAVL+ E I+A RG+A+G VQS WA+GWG +L+S++F++LP E AWR +F++GLLP Sbjct: 135 AGAVLIGEVIKARDRGKAVGLVQSGWAIGWGLTAILYSLMFSLLPPEEAWRALFMLGLLP 194 Query: 182 ALLVVYVRRSVSETDAFLAGRKAATSKPAASTLLGIFRPDVLRLTLIGSLLGVGAHGGYY 241 AL V+ VRR V E + + R+ S IF P +L +TL SLL GA GGYY Sbjct: 195 ALFVLVVRRLVKEPEIYREARQRNQGADKVS-FYEIFAPGMLSITLRASLLTTGALGGYY 253 Query: 242 ALMTWLPTYLKTEKHLSVLSTGGYLAVIIIAFWCGCIASAQLLDRIGRRRTVASFALCCV 301 A+ WLPT+LKTE+ L+VL T GYLA++I+ + G + SA L D IGR++ FA+ Sbjct: 254 AITAWLPTFLKTERGLTVLGTSGYLAMVILGSYVGYVVSAFLTDLIGRKKNFVLFAVGSF 313 Query: 302 ATVLCYIFLPLTDTQMLICGFPLGFFAAGIPASLGALFNELYPSGIRGTGVGFCYNFGRV 361 VL Y LP+++ ML GFPLGFFA+GI + +G+ EL+P+ IRG+G GFCYN GR Sbjct: 314 TVVLLYTQLPVSNGAMLWLGFPLGFFASGIFSGMGSFLTELFPTRIRGSGQGFCYNAGRA 373 Query: 362 ASAGFPVLVGHMSDSMPLGQAIGMRAFKSLGGIDAAIAYSLVVIAVLMLPETKGRQME 419 +A FP+L+G + + LG IG AF AA++Y +V++A L LPET+G+Q+E Sbjct: 374 IAALFPMLIGMLGQKLSLGLGIG--AF-------AAVSYGVVILAALSLPETRGKQLE 422 >PM0835 [GEPR] COG0477 Permeases of the major facilitator superfamily Pmu Pasteurella multocida Length = 405 Score = 182 bits (462), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 131/403 (32%), Positives = 202/403 (50%), Gaps = 21/403 (5%) Query: 22 GWALDALDVQMFSLAIPALIAAFSLSKADAGMISGATLVASAIGGWFAGALSDRYGRVKT 81 G+A+D D+ + + A+ A +L+ A +G + TL+ + GG GALSD+YGRV+ Sbjct: 19 GYAMDGFDLLILGFMLSAISADLALTPAQSGSLVTWTLIGAVAGGIIFGALSDKYGRVRV 78 Query: 82 LQITIIWFSFFTFLSAFAQSYPQLLVLKALQGFGFGGEWAAGAVLMAETIRAEHRGRAMG 141 L TI+ F+ FT L AFAQ Y LL+ + + G G GGE+ G L AE A HR +A Sbjct: 79 LTWTIVLFAVFTGLCAFAQGYWDLLIYRTIAGIGLGGEFGIGMALAAEAWPARHRAKASS 138 Query: 142 TVQSAWAVGWGGAVLLFSVLFTMLPQEMAWRVMFVIGLLPALLVVYVRRSVSETDAFLAG 201 V W VG VL ++L +L + WR MF++G+ PA + Y+R + E + F+ Sbjct: 139 YVALGWQVG----VLGAALLTPLLLPHIGWRGMFLVGIFPAFVAWYLRAKLHEPEIFVK- 193 Query: 202 RKAATSKPAASTL----LGIFRPDVLRLTLIGSLLGVGAHGGYYALMTWLPTYLKTEKHL 257 ++ A + S L L I +++ +L + GYY +M W+P +L + Sbjct: 194 KQTALERQKTSRLEPFRLLIKDKATAKISAGIVVLTSVQNFGYYGIMIWMPNFLSKQLGF 253 Query: 258 SVLSTGGYLAVIIIAFWCGCIASAQLLDRIGRRRTVASFALCCVATVLCYIFLPLTD-TQ 316 S+ +G + AV I G QL DRIGR+ + F V ++ Y ++D T Sbjct: 254 SLTKSGVWTAVTICGMMFGIWLFGQLADRIGRKPSFLLFQFGAVISIFTYS--QMSDPTY 311 Query: 317 MLICGFPLGFFAAGIPASLGALFNELYPSGIRGTGVGFCYNFGRVASAGFPVLVGHMSDS 376 ML G LG F G+ GAL +E YP+ R T +N GR P++VG + + Sbjct: 312 MLFAGAVLGMFVNGMMGGYGALMSEAYPTQARATAQNVLFNLGRAVGGFGPIVVGALVST 371 Query: 377 MPLGQAIGMRAFKSLGGIDAAIAYSLVVIAVLMLPETKGRQME 419 AI A S+ ID ++ + ++PE KG+Q++ Sbjct: 372 YSFQLAIAFLA--SIYIID-------MIATIFLIPELKGKQLD 405 >RSp0797 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 418 Score = 176 bits (446), Expect = 1e-43, Method: Compositional matrix adjust. Identities = 139/399 (34%), Positives = 207/399 (51%), Gaps = 19/399 (4%) Query: 22 GWALDALDVQMFSLAIPALIAAFSLSKADAGMISGATLVASAIGGWFAGALSDRYGRVKT 81 G+A+D D+ + +PA+ AA +L+ ++G + TLV + GG GALSD YGRV+ Sbjct: 36 GYAMDGFDLLILGFMLPAISAALALTPGESGALVTWTLVGAVAGGILFGALSDAYGRVRV 95 Query: 82 LQITIIWFSFFTFLSAFAQSYPQLLVLKALQGFGFGGEWAAGAVLMAETIRAEHRGRAMG 141 L TI+ F+ FT + AFAQ + LL+ + + G G GGE+ G L AE A R R Sbjct: 96 LTWTIVLFAVFTGMCAFAQGFTDLLIYRTIAGIGLGGEFGIGMALAAEAWPAHKRAR--- 152 Query: 142 TVQSAWAVGWGGAVLLFSVLFTMLPQEMAWRVMFVIGLLPALLVVYVRRSVSETDAFLAG 201 V S A+GW VLL ++L +L + WR MF++G+LPA + ++R + E + F+ Sbjct: 153 -VSSYVALGWQCGVLLAALLTPLLLPFIGWRGMFLLGVLPAAVAWFIRNRLHEPELFVRH 211 Query: 202 RKAATSKPAASTLLGIFRPDVLRLTLIGSLLGVGAHGGYYALMTWLPTYLKTEKHLSVLS 261 A K +A LL + LR +L +L + GYY +M WLPTYL S+ Sbjct: 212 AHAPRGKTSAFRLL-VSDARTLRTSLGIVILCAVQNFGYYGIMIWLPTYLGKTLGFSLTK 270 Query: 262 TGGYLAVIIIAFWCGCIASAQLLDRIGRRRTVASFALCCVATVLCYIFLPLTDTQMLI-C 320 + + +V I+ G +A L DRIGR+ T F VA VL Y LTD L+ Sbjct: 271 SALWTSVTILGMMLGIVAFGHLADRIGRKPTFLIFQAGAVAMVLTYA--RLTDPLALLWA 328 Query: 321 GFPLGFFAAGIPASLGALFNELYPSGIRGTGVGFCYNFGRVASAGFPVLVGHMSDSMPLG 380 G +G F G+ GAL +E +P+ R T +N GR PV+VG ++ + Sbjct: 329 GAVMGMFVNGMIGGYGALISEAFPTAARATAQNVLFNLGRAVGGFGPVVVGSLAAAYSFR 388 Query: 381 QAIGMRAFKSLGGIDAAIAYSLVVIAVL-MLPETKGRQM 418 AI + L G+ Y L ++A + ++PE KG ++ Sbjct: 389 TAIAL-----LAGL-----YVLDMLATMALVPERKGAEL 417