BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0033.0087.p (408 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp0834 [GEPR] COG0477 Permeases of the major facilitator superf... 507 e-143 YPO0577 [GEPR] COG0477 Permeases of the major facilitator superf... 482 e-136 exuT [GEPR] COG0477 Permeases of the major facilitator superfami... 474 e-133 ZexuT [GEPR] COG0477 Permeases of the major facilitator superfam... 474 e-133 ECs3975 [GEPR] COG0477 Permeases of the major facilitator superf... 474 e-133 >RSp0834 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 435 Score = 507 bits (1305), Expect = e-143, Method: Compositional matrix adjust. Identities = 256/412 (62%), Positives = 312/412 (75%), Gaps = 6/412 (1%) Query: 1 MVTLVTLALIVNYLARNTLSVAAPTMMKELDMSTQQYSYIVVAWQICYAVMQPVAGYVLD 60 M+ LV LI+NYLARN L+ AAP + K L ++TQQY YIV A+Q Y VMQPVAGYVLD Sbjct: 11 MIGLVLTGLIMNYLARNALAAAAPEVNKVLGITTQQYGYIVAAFQAAYMVMQPVAGYVLD 70 Query: 61 AVGTKIGFGIFALAWSLVCAAAALATGWQSLAFFRALLGMTEAAGIPGGVKASTEWFPAK 120 +GTK+GF +FA AWS+VC + A W SLA FRA+LG+TEAAG P ++A++EWFPAK Sbjct: 71 VLGTKLGFALFAGAWSVVCILHSTAGNWVSLAVFRAMLGVTEAAGFPSALRATSEWFPAK 130 Query: 121 ERSVAIGWFNIGSSIGALCAPPLVVWTILHGGWKMSFVVVGVLGVLWFFLWMLFYKSPRD 180 ERS+A GWFNIGSS+GAL APPLVVW ILHG W+ +F V+GVLG++W LW + Y+ P Sbjct: 131 ERSIATGWFNIGSSVGALVAPPLVVWCILHGNWRFAFAVIGVLGLVWSALWFMLYRVPAR 190 Query: 181 QKLLSPEERDYILDGQEKTPE---KVVRESWTKIVRSQNFWSIAIPRFLSEPAWQTFNAW 237 LS EE YI GQE TP V+ SW +I+ + FW IAIPRFL+EPAWQTFN W Sbjct: 191 HPRLSAEEHAYIRAGQE-TPAPGADAVKPSWREIMSGRRFWGIAIPRFLTEPAWQTFNFW 249 Query: 238 IPLYMATERHMNIKEIAMFAWLPFLAADIGCVLGGYLSPFFHKHLNVSLFTSRKLVMLVG 297 IPLYMATERHMN+KEIAMFAWLPFLAAD+GCVLGGYL+P++ K + SL TSRK+VM+ G Sbjct: 250 IPLYMATERHMNLKEIAMFAWLPFLAADVGCVLGGYLAPWYQKRFSTSLITSRKMVMVTG 309 Query: 298 SLAMIGPACVGFVDSPYVAIALLSIGGFAHQTLSGALYSITSDVFTKNQVATATGLTGMS 357 ++ MIGPAC+G SPY AIAL +GGFAHQTLSGALY++TSDVF K++V TA GL GMS Sbjct: 310 AVCMIGPACIGLATSPYTAIALFCVGGFAHQTLSGALYTLTSDVFGKHEVGTAVGLAGMS 369 Query: 358 GYLGATLFTLLFGILVTQIGYGPLFVLLAAFDLVAVAVVFAIARP--RPEAI 407 G+LG TLF+L G L + IGY PLF LA FD+ A V++ + R RP A+ Sbjct: 370 GFLGGTLFSLAVGTLASTIGYNPLFAALALFDIAAAIVMWNVLREPRRPMAM 421 >YPO0577 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 434 Score = 482 bits (1240), Expect = e-136, Method: Compositional matrix adjust. Identities = 225/405 (55%), Positives = 300/405 (74%), Gaps = 2/405 (0%) Query: 1 MVTLVTLALIVNYLARNTLSVAAPTMMKELDMSTQQYSYIVVAWQICYAVMQPVAGYVLD 60 M+ LVT+ I+ YL RN ++VAAPT+ ++L ++TQQYSYI+ A+ Y +MQPVAGYVLD Sbjct: 12 MIALVTVGTILGYLTRNAIAVAAPTLQEQLHITTQQYSYIIAAYSAAYTLMQPVAGYVLD 71 Query: 61 AVGTKIGFGIFALAWSLVCAAAALATGWQSLAFFRALLGMTEAAGIPGGVKASTEWFPAK 120 +GTK+G+ +FA+ W++ C + ALA+ W LA R +GM EAA IP G+KAS+EWFPAK Sbjct: 72 VMGTKVGYAMFAVMWAIFCMSTALASSWGGLAIARGAVGMAEAAMIPAGLKASSEWFPAK 131 Query: 121 ERSVAIGWFNIGSSIGALCAPPLVVWTILHGGWKMSFVVVGVLGVLWFFLWMLFYKSPRD 180 ERS+A+G+FN+GSSIG + APPLVVW I+ W+M+F++ GVL ++W W++ YK P+D Sbjct: 132 ERSIAVGYFNVGSSIGGMIAPPLVVWAIVMHSWQMAFIITGVLSLIWAIAWLILYKHPKD 191 Query: 181 QKLLSPEERDYILDGQE--KTPEKVVRESWTKIVRSQNFWSIAIPRFLSEPAWQTFNAWI 238 QK LS EER+YIL GQE + + S +I+R++ FW IAIPRFL+EPAW TFNAWI Sbjct: 192 QKRLSDEEREYILSGQEAQHSTANAKKMSAMQIIRNRQFWGIAIPRFLAEPAWGTFNAWI 251 Query: 239 PLYMATERHMNIKEIAMFAWLPFLAADIGCVLGGYLSPFFHKHLNVSLFTSRKLVMLVGS 298 PL+M N+KEIAMFAW+P L AD+GC+LGGYL P F K+ V+L SRKLV+ +G Sbjct: 252 PLFMFKAYGFNLKEIAMFAWMPMLFADVGCILGGYLPPLFQKYFKVNLIVSRKLVVTMGG 311 Query: 299 LAMIGPACVGFVDSPYVAIALLSIGGFAHQTLSGALYSITSDVFTKNQVATATGLTGMSG 358 + MIGP +G SPY AIALL IGGFAHQ LSGAL +++SDVF +N+VATA GLTGM+ Sbjct: 312 VLMIGPGTIGLFTSPYAAIALLCIGGFAHQALSGALITLSSDVFGRNEVATANGLTGMAA 371 Query: 359 YLGATLFTLLFGILVTQIGYGPLFVLLAAFDLVAVAVVFAIARPR 403 + +TLF L+ G L +G+ PLF LA FDL+AV V++ + + R Sbjct: 372 WTASTLFALVVGALADTMGFSPLFAALAVFDLLAVVVIWTVLQDR 416 >exuT [GEPR] COG0477 Permeases of the major facilitator superfamily Eco Escherichia coli K12 Length = 472 Score = 474 bits (1220), Expect = e-133, Method: Compositional matrix adjust. Identities = 228/406 (56%), Positives = 302/406 (74%), Gaps = 2/406 (0%) Query: 1 MVTLVTLALIVNYLARNTLSVAAPTMMKELDMSTQQYSYIVVAWQICYAVMQPVAGYVLD 60 M+ LVTL ++ YL RNT++ AAPT+M+EL++STQQYSYI+ A+ Y VMQPVAGYVLD Sbjct: 51 MIALVTLGTVLGYLTRNTVAAAAPTLMEELNISTQQYSYIIAAYSAAYTVMQPVAGYVLD 110 Query: 61 AVGTKIGFGIFALAWSLVCAAAALATGWQSLAFFRALLGMTEAAGIPGGVKASTEWFPAK 120 +GTKIG+ +FA+ W++ C A ALA W LA R +G EAA IP G+KAS+EWFPAK Sbjct: 111 VLGTKIGYAMFAVLWAVFCGATALAGSWGGLAVARGAVGAAEAAMIPAGLKASSEWFPAK 170 Query: 121 ERSVAIGWFNIGSSIGALCAPPLVVWTILHGGWKMSFVVVGVLGVLWFFLWMLFYKSPRD 180 ERS+A+G+FN+GSSIGA+ APPLVVW I+ W+M+F++ G L +W W++FYK PRD Sbjct: 171 ERSIAVGYFNVGSSIGAMIAPPLVVWAIVMHSWQMAFIISGALSFIWAMAWLIFYKHPRD 230 Query: 181 QKLLSPEERDYILDGQEKTPE--KVVRESWTKIVRSQNFWSIAIPRFLSEPAWQTFNAWI 238 QK L+ EERDYI++GQE + + S +I+R++ FW IA+PRFL+EPAW TFNAWI Sbjct: 231 QKHLTDEERDYIINGQEAQHQVSTAKKMSVGQILRNRQFWGIALPRFLAEPAWGTFNAWI 290 Query: 239 PLYMATERHMNIKEIAMFAWLPFLAADIGCVLGGYLSPFFHKHLNVSLFTSRKLVMLVGS 298 PL+M N+KEIAMFAW+P L AD+GC+LGGYL P F + V+L SRK+V+ +G+ Sbjct: 291 PLFMFKVYGFNLKEIAMFAWMPMLFADLGCILGGYLPPLFQRWFGVNLIVSRKMVVTLGA 350 Query: 299 LAMIGPACVGFVDSPYVAIALLSIGGFAHQTLSGALYSITSDVFTKNQVATATGLTGMSG 358 + MIGP +G +PYVAI LL IGGFAHQ LSGAL +++SDVF +N+VATA GLTGMS Sbjct: 351 VLMIGPGMIGLFTNPYVAIMLLCIGGFAHQALSGALITLSSDVFGRNEVATANGLTGMSA 410 Query: 359 YLGATLFTLLFGILVTQIGYGPLFVLLAAFDLVAVAVVFAIARPRP 404 +L +TLF L+ G L IG+ PLF +LA FDL+ V++ + + +P Sbjct: 411 WLASTLFALVVGALADTIGFSPLFAVLAVFDLLGALVIWTVLQNKP 456 >ZexuT [GEPR] COG0477 Permeases of the major facilitator superfamily EcZ Escherichia coli O157:H7 EDL933 Length = 472 Score = 474 bits (1220), Expect = e-133, Method: Compositional matrix adjust. Identities = 228/406 (56%), Positives = 302/406 (74%), Gaps = 2/406 (0%) Query: 1 MVTLVTLALIVNYLARNTLSVAAPTMMKELDMSTQQYSYIVVAWQICYAVMQPVAGYVLD 60 M+ LVTL ++ YL RNT++ AAPT+M+EL++STQQYSYI+ A+ Y VMQPVAGYVLD Sbjct: 51 MIALVTLGTVLGYLTRNTVAAAAPTLMEELNISTQQYSYIIAAYSAAYTVMQPVAGYVLD 110 Query: 61 AVGTKIGFGIFALAWSLVCAAAALATGWQSLAFFRALLGMTEAAGIPGGVKASTEWFPAK 120 +GTKIG+ +FA+ W++ C A ALA W LA R +G EAA IP G+KAS+EWFPAK Sbjct: 111 VLGTKIGYAMFAVLWAVFCGATALAGSWGGLAVARGAVGAAEAAMIPAGLKASSEWFPAK 170 Query: 121 ERSVAIGWFNIGSSIGALCAPPLVVWTILHGGWKMSFVVVGVLGVLWFFLWMLFYKSPRD 180 ERS+A+G+FN+GSSIGA+ APPLVVW I+ W+M+F++ G L +W W++FYK PRD Sbjct: 171 ERSIAVGYFNVGSSIGAMIAPPLVVWAIVMHSWQMAFIISGALSFIWAMAWLIFYKHPRD 230 Query: 181 QKLLSPEERDYILDGQEKTPE--KVVRESWTKIVRSQNFWSIAIPRFLSEPAWQTFNAWI 238 QK L+ EERDYI++GQE + + S +I+R++ FW IA+PRFL+EPAW TFNAWI Sbjct: 231 QKHLTDEERDYIINGQEAQHQVSTAKKMSVGQILRNRQFWGIALPRFLAEPAWGTFNAWI 290 Query: 239 PLYMATERHMNIKEIAMFAWLPFLAADIGCVLGGYLSPFFHKHLNVSLFTSRKLVMLVGS 298 PL+M N+KEIAMFAW+P L AD+GC+LGGYL P F + V+L SRK+V+ +G+ Sbjct: 291 PLFMFKVYGFNLKEIAMFAWMPMLFADLGCILGGYLPPLFQRWFGVNLIVSRKMVVTLGA 350 Query: 299 LAMIGPACVGFVDSPYVAIALLSIGGFAHQTLSGALYSITSDVFTKNQVATATGLTGMSG 358 + MIGP +G +PYVAI LL IGGFAHQ LSGAL +++SDVF +N+VATA GLTGMS Sbjct: 351 VLMIGPGMIGLFTNPYVAIMLLCIGGFAHQALSGALITLSSDVFGRNEVATANGLTGMSA 410 Query: 359 YLGATLFTLLFGILVTQIGYGPLFVLLAAFDLVAVAVVFAIARPRP 404 +L +TLF L+ G L IG+ PLF +LA FDL+ V++ + + +P Sbjct: 411 WLASTLFALVVGALADTIGFSPLFAVLAVFDLLGALVIWTVLQNKP 456 >ECs3975 [GEPR] COG0477 Permeases of the major facilitator superfamily Ecs Escherichia coli O157:H7 Length = 472 Score = 474 bits (1220), Expect = e-133, Method: Compositional matrix adjust. Identities = 228/406 (56%), Positives = 302/406 (74%), Gaps = 2/406 (0%) Query: 1 MVTLVTLALIVNYLARNTLSVAAPTMMKELDMSTQQYSYIVVAWQICYAVMQPVAGYVLD 60 M+ LVTL ++ YL RNT++ AAPT+M+EL++STQQYSYI+ A+ Y VMQPVAGYVLD Sbjct: 51 MIALVTLGTVLGYLTRNTVAAAAPTLMEELNISTQQYSYIIAAYSAAYTVMQPVAGYVLD 110 Query: 61 AVGTKIGFGIFALAWSLVCAAAALATGWQSLAFFRALLGMTEAAGIPGGVKASTEWFPAK 120 +GTKIG+ +FA+ W++ C A ALA W LA R +G EAA IP G+KAS+EWFPAK Sbjct: 111 VLGTKIGYAMFAVLWAVFCGATALAGSWGGLAVARGAVGAAEAAMIPAGLKASSEWFPAK 170 Query: 121 ERSVAIGWFNIGSSIGALCAPPLVVWTILHGGWKMSFVVVGVLGVLWFFLWMLFYKSPRD 180 ERS+A+G+FN+GSSIGA+ APPLVVW I+ W+M+F++ G L +W W++FYK PRD Sbjct: 171 ERSIAVGYFNVGSSIGAMIAPPLVVWAIVMHSWQMAFIISGALSFIWAMAWLIFYKHPRD 230 Query: 181 QKLLSPEERDYILDGQEKTPE--KVVRESWTKIVRSQNFWSIAIPRFLSEPAWQTFNAWI 238 QK L+ EERDYI++GQE + + S +I+R++ FW IA+PRFL+EPAW TFNAWI Sbjct: 231 QKHLTDEERDYIINGQEAQHQVSTAKKMSVGQILRNRQFWGIALPRFLAEPAWGTFNAWI 290 Query: 239 PLYMATERHMNIKEIAMFAWLPFLAADIGCVLGGYLSPFFHKHLNVSLFTSRKLVMLVGS 298 PL+M N+KEIAMFAW+P L AD+GC+LGGYL P F + V+L SRK+V+ +G+ Sbjct: 291 PLFMFKVYGFNLKEIAMFAWMPMLFADLGCILGGYLPPLFQRWFGVNLIVSRKMVVTLGA 350 Query: 299 LAMIGPACVGFVDSPYVAIALLSIGGFAHQTLSGALYSITSDVFTKNQVATATGLTGMSG 358 + MIGP +G +PYVAI LL IGGFAHQ LSGAL +++SDVF +N+VATA GLTGMS Sbjct: 351 VLMIGPGMIGLFTNPYVAIMLLCIGGFAHQALSGALITLSSDVFGRNEVATANGLTGMSA 410 Query: 359 YLGATLFTLLFGILVTQIGYGPLFVLLAAFDLVAVAVVFAIARPRP 404 +L +TLF L+ G L IG+ PLF +LA FDL+ V++ + + +P Sbjct: 411 WLASTLFALVVGALADTIGFSPLFAVLAVFDLLGALVIWTVLQNKP 456