BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0033.0069.p (1062 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp1597 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia s... 1506 0.0 SMa0875 [V] COG0841 Cation/multidrug efflux pump Sme Sinorhizobi... 396 e-109 aq_786 [V] COG0841 Cation/multidrug efflux pump Aae Aquifex aeol... 369 e-101 BH3816 [V] COG0841 Cation/multidrug efflux pump Bha Bacillus hal... 350 2e-95 AGl494 [V] COG0841 Cation/multidrug efflux pump Atu Agrobacteriu... 343 1e-93 >RSp1597 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia solanacearum Length = 1064 Score = 1506 bits (3899), Expect = 0.0, Method: Compositional matrix adjust. Identities = 759/1054 (72%), Positives = 880/1054 (83%), Gaps = 5/1054 (0%) Query: 1 MNMVALALRRPYTFIVMALLIVLATPLTLKNMATDIFPEINIPVVSVIWNYNGLSAQEMG 60 M +V LALRRP TFIV+ALLI+LATP L MATDIFPEI+IPV S+IWNYNGL A+EM Sbjct: 1 MWIVQLALRRPLTFIVLALLILLATPFVLMRMATDIFPEIDIPVCSIIWNYNGLPAKEMA 60 Query: 61 QRIAAQNERGLTTVVSDIEHIESQSLAGVAVIKVFFQPKANIQTAIAQVVASVQSQLRQL 120 RI + ER LTT V+DIEHIESQSL GV++IKVFFQP ANIQTA+AQ+V+ Q+QLRQL Sbjct: 61 DRIVSVTERSLTTTVNDIEHIESQSLGGVSIIKVFFQPTANIQTALAQIVSVSQAQLRQL 120 Query: 121 PPGITPPLVIKYSASSIPVMQLALSSPTLPEQTVFDTAVQTLRPQLITIPGVAVPFPYGG 180 PPGITPPLVIKYSASSIP++QL LSS TL EQ + D A+ LRP+LIT+PG+AVPFPYGG Sbjct: 121 PPGITPPLVIKYSASSIPILQLGLSSNTLSEQELNDAALNFLRPRLITVPGIAVPFPYGG 180 Query: 181 KTRLISVDLDTPALQSRGLSPIDVVNAINTQNLILPSGTAKFGGTEYSVKLNGSPEAVAG 240 K+R I+VDLDT L ++GL+P D+VNA++ QNLILP+GT K +EY+V LNG+P +A Sbjct: 181 KSRQITVDLDTQKLLAQGLTPTDIVNAVSAQNLILPAGTQKIDASEYAVALNGTPGTIAQ 240 Query: 241 LNELPVRTANGATIYLKDVANVRDGFSPQTNVVRQDGARGVLLSILKNGGASTLDIVDNL 300 LN +PVRT NGAT+ L DVANVRDGFSPQTNVVRQDG RGVLLSILKNGGASTLDIV N+ Sbjct: 241 LNAMPVRTRNGATLVLGDVANVRDGFSPQTNVVRQDGQRGVLLSILKNGGASTLDIVSNI 300 Query: 301 RKLLPTAAQTLPEDIKITPLFDQSLFVKAAVTGVISEALIAAGLTAAMVLLFLGNWRSTL 360 KLLP AA LP+DIKITPLFDQSLFVKAA+ GVI EALIAA LTAAM+LLFLGNWRST Sbjct: 301 YKLLPVAATALPQDIKITPLFDQSLFVKAAIEGVIREALIAACLTAAMILLFLGNWRSTA 360 Query: 361 IIGLTIPLSIMAAILMLAALGETLNLMTLGGLALSVGILVDQAIVTIENIERHLHLGKPL 420 II ++IPLSI+++I++L LGET+NLMTLGGLAL+VGILVD A VTIENIERHLH GK Sbjct: 361 IIAVSIPLSILSSIIVLHLLGETINLMTLGGLALAVGILVDDATVTIENIERHLHEGKAP 420 Query: 421 HDAIIVGAGEIGVPAFVATLCICIVFVPMFFLSGVARFLFVPLAEAVVFAMAASYLLSRT 480 AI+ GA EI VPAFV+TLCICIVFVPMFFL+GVAR+LFVP+AEAV+FAM ASY+LSRT Sbjct: 421 ITAILDGAAEIAVPAFVSTLCICIVFVPMFFLTGVARYLFVPMAEAVIFAMLASYVLSRT 480 Query: 481 LVPTLVMLLMGSHGQVDSAKQSLLQRLYRAFDNRFERVRHGYTLVLSSLLAHRRRFALGF 540 LVPTLVM+LM H + D+ K ++ +Y+AF+ RFE +R Y +L LL HRR FAL F Sbjct: 481 LVPTLVMMLMTGHTE-DAKKPGPMRYIYQAFNARFEHMRGNYAAILGGLLEHRRVFALSF 539 Query: 541 LGFCLLSCLLYPFLGRDFFPNVDGGQIRLHMRMPTGTRIEETARAADEVERVIRSLIPAS 600 LGFC+ SC LY LGRDFFP+VD GQIRLHMR P+G RIEETAR ADEVE IR++IP + Sbjct: 540 LGFCVASCALYLALGRDFFPDVDAGQIRLHMRAPSGLRIEETARLADEVEAAIRTIIPRN 599 Query: 601 ELETILDNLGVPNSGINLSYSNAGTIGTLDGEILMALKEGHR-PTEELVSLLREQLPRRF 659 EL T+LDNLGVPNSGINLSYSNAGTIGTLDGEIL+AL+EG R P+ E V LRE+LP+RF Sbjct: 600 ELATLLDNLGVPNSGINLSYSNAGTIGTLDGEILIALREGERKPSAEYVRRLREELPKRF 659 Query: 660 PGIEFFFQPADIVTQILNFGLPAAIDVQFTGPNMEANARLAAELTKQIRQIPGAVDAHVH 719 PG+EF FQPADIV+QILNFGLP+AIDVQF+G ++ AN +LA L +IR+IPGAVD HVH Sbjct: 660 PGVEFAFQPADIVSQILNFGLPSAIDVQFSGADVAANQQLAGILANRIRRIPGAVDTHVH 719 Query: 720 QRLDGPSLDLRMDRTRLQQFGLSAANVGQNLLIALSGSSQTQPAFWLNPNNGVVYSIAVQ 779 QR D P+L + MDRTR+QQ GL +V QNLL++LS S QT P FWLNP NGVVY +AVQ Sbjct: 720 QRFDQPTLAVNMDRTRIQQVGLQGRDVAQNLLVSLSSSFQTSPTFWLNPVNGVVYQVAVQ 779 Query: 780 SPQYQVDSLDALLNIPV-GAGANAATP--PQLLGNLVDVHAGRQMAVASRYNISPAIDVY 836 SPQY+VDSLDALL PV GAG A P PQLLGNLV V Q V S Y+I+P +DVY Sbjct: 780 SPQYRVDSLDALLRTPVAGAGGGATQPGGPQLLGNLVQVGPAVQPQVVSHYDITPVVDVY 839 Query: 837 VSVQGTDLASVAGKVAKLVEEIKPKLARGSQVVIRGQVETMQSSFIGLGVGLAMAIVLVY 896 +VQG DL +VA +V K V+EI+PKL RG+Q+ +RGQV TM+SSF+GLGVGL MAIVLVY Sbjct: 840 AAVQGRDLGAVAKEVQKAVDEIRPKLPRGAQITVRGQVRTMESSFVGLGVGLVMAIVLVY 899 Query: 897 LLVVVNFQSWIDAAIIIAALPAALAGIAWMLFLTGTTLSVPALTGAIMTMGVATANSILI 956 LL+VVNFQSWID II+ ALPAALAGIAWMLF+TGTTLSVP+LTGAIMTMGVATANSIL+ Sbjct: 900 LLIVVNFQSWIDPLIIVTALPAALAGIAWMLFVTGTTLSVPSLTGAIMTMGVATANSILL 959 Query: 957 VAFARQRREEGATPLASALEAGSTRIRPVLMTALAMIIGMIPMALGLGEGAEQNAPLGRA 1016 ++FAR+R EG P+ +ALEAG+TR+RPVLMTALAMIIGM+PMALGLGEGAEQNAPLGRA Sbjct: 960 ISFARERLHEGIAPMQAALEAGATRLRPVLMTALAMIIGMVPMALGLGEGAEQNAPLGRA 1019 Query: 1017 VIGGLLLATVSTLFFVPVVFAGVHQRLARRAERR 1050 VIGGLL ATVSTLFFVPVVFA VH RL RRA RR Sbjct: 1020 VIGGLLFATVSTLFFVPVVFASVHGRLQRRAGRR 1053 >SMa0875 [V] COG0841 Cation/multidrug efflux pump Sme Sinorhizobium meliloti Length = 1065 Score = 396 bits (1018), Expect = e-109, Method: Compositional matrix adjust. Identities = 313/1056 (29%), Positives = 513/1056 (48%), Gaps = 43/1056 (4%) Query: 1 MNMVALALRRPYTFIVMALLIVLATPLTLKNMATDIFPEINIPVVSVIWNYNGLSAQEMG 60 M + +++ P +M ++I++ + + D +PE ++PVV V Y G S + + Sbjct: 1 MFLTRISINHPVFATMMMVMILVLGLFSYGRLGVDHYPETDLPVVVVATTYTGASPESVE 60 Query: 61 QRIAAQNERGLTTVVSDIEHIESQSLAGVAVIKVFFQPKANIQTAIAQVVASVQSQLRQL 120 I+ E L T+ I+ I S+S G +++ V F+ + Q A +V V + Sbjct: 61 SEISRPIEAALNTI-GGIDTITSESYEGRSIVVVQFEVDVDSQDAAQEVRDRVARLETKF 119 Query: 121 PPGITPPLVIKYSASSIPVMQLALSSP--TLPEQTVFDTAVQTLRPQLITIPGVAVPFPY 178 P G+ P V +Y ++ +A+SS TLPE T T V + +L I GV Sbjct: 120 PDGVATPQVTRYKPEGQAILSVAVSSTSRTLPEITTLATRV--INNRLSVISGVGQVSLI 177 Query: 179 GGKTRLISVDLDTPALQSRGLSPIDVVNAINTQNLILPSGTAKFGGTEYSVKLNGSPEAV 238 G R + V +D L + GL+ V+ AI +N +GT G + V + G Sbjct: 178 GSSERQVLVVVDPDRLGAYGLAVSTVIEAIRGENQDRAAGTLISGINQRIVTVEGRIANT 237 Query: 239 AGLNELPVRTANGATIYLKDVANVRDGFSPQTNVVRQDGARGVLLSILKNGGASTLDIVD 298 +G N + V NG +YL +VA + D + T++ G + L I+K GA+T+++ Sbjct: 238 SGFNRIIVAQRNGYPVYLSEVATILDTGAEVTSLANYQGQTTLGLHIVKVQGANTVEVAS 297 Query: 299 NLRKLLPTAAQTLPED-IKITPLFDQSLFVKAAVTGVISEALIAAG-LTAAMVLLFLGNW 356 +R+ + L +D +++T D S + + V+ V L+ G L+ +V +FL +W Sbjct: 298 AVRREVSALNAELTKDNVQLTITRDNSRPIASQVSQV-QRTLVEGGVLSVLIVFIFLNSW 356 Query: 357 RSTLIIGLTIPLSIMAAILMLAALGETLNLMTLGGLALSVGILVDQAIVTIENIERHLHL 416 RST+I GLT+P+S++ + ALG TLN+MTL L+LS+GIL+D AIV ENI RHL + Sbjct: 357 RSTVITGLTLPISVIGTFAAIYALGFTLNIMTLMALSLSIGILIDDAIVVRENITRHLQM 416 Query: 417 GKPLHDAIIVGAGEIGVPAFVATLCICIVFVPMFFLSGVARFLFVPLAEAVVFAMAASYL 476 GK A + G EIG+ TLCI VF+P+ F+ G+ F+ V A+ S Sbjct: 417 GKDPVRAALDGTNEIGLAVLSTTLCIVAVFLPVAFMGGLIGRFFLQFGVTVAVAVVISLF 476 Query: 477 LSRTLVPTLVMLLMGSHGQVDSAKQSLLQRLYRAFDNRFERVRHGYTLVLSSLLAHRRRF 536 +S TL P L + Q +AK+ +L FD FE + Y V+ +R+ Sbjct: 477 VSFTLDPMLSSVWCDPQSQ-KTAKRGFFGQLIERFDQWFEGLASRYRSVIYFTFDYRKTT 535 Query: 537 ALGFLGFCLLSCLLYPFLGRDFFPNVDGGQIRLHMRMPTGTRIEETARAADEVERVIRSL 596 LG ++S LL P +G +F P D G++ + + G ++ A ++ER +R Sbjct: 536 IAIVLGMFVVSLLLVPRIGTEFLPPPDQGEVSISLEANEGASLDYMAAKVGQIERALR-- 593 Query: 597 IPASELETILDNLGVPNSGINLSYSNAGTIGTLDGEILMALKEGHRPTEELVSLLREQLP 656 E + NSG ++ A L L+ + T E + +R +L Sbjct: 594 ----EFNYVSSTYSTINSGEMRGFNKA-----LVAVQLVHSSQRRLKTAETLGPIRRRLS 644 Query: 657 RRFPGIEFFF-QPADIVTQILNFGLPAAIDVQFTGPNMEANARLAAELTKQIRQIPGAVD 715 R G+E Q +++V I + + G E R++ +T + IPGA + Sbjct: 645 R-IAGLEISVGQRSEVVGSI------KPLQLSILGDGDEELRRISDHITSVLAAIPGATE 697 Query: 716 AHVHQRLDGPSLDLRMDRTRLQQFGLSAANVGQNLLIALSGSSQTQPAFWLNPNNGVVYS 775 P+L +R+ R G+S A +G L ++G + + W +P+ G + Sbjct: 698 IESSIEKLRPTLAVRVRREAASDLGVSIATIGDTLRSLVAGDA---ISVWNSPD-GETHD 753 Query: 776 IAVQSPQYQVDSLDALLNIPVGAG---ANAATPPQLLGNLVDVHAGRQMAVASRYNISPA 832 + V+ P ++ L N+P+ N LL + DV A +R ++S Sbjct: 754 VVVRLPAAGRENAAQLRNLPIATARMDDNGKPIMVLLDQVADVVESTAPAQITRKDLSRD 813 Query: 833 IDVYVSVQGTDLASVAGKVAKLVEEIKPKLARGSQVVIRGQVETMQSSFIGLGVGLAMAI 892 I + +++G L V + + K + G ++ G E + S LAMA+ Sbjct: 814 IRISSNIEGRTLGDVVADLKAAMT--KMDIPVGFRISFGGDAENLTESTAYALQSLAMAV 871 Query: 893 VLVYLLVVVNFQSWIDAAIIIAALPAALAGIAWMLFLTGTTLSVPALTGAIMTMGVATAN 952 + +Y+++ F S+I II +P +L G+ L TG+TL++ ++ G +M MG+ T N Sbjct: 872 IFIYIILASQFGSFIQPIAIIMTMPLSLMGVLLGLLFTGSTLNMFSMIGIMMLMGLVTKN 931 Query: 953 SILIVAFARQRREEGATPLASALEAGSTRIRPVLMTALAMIIGMIPMALGLGEGAEQNAP 1012 +IL+V ++ EG + S +AG+ R+RP++MT LAMI GM+P ALGLGEG Q AP Sbjct: 932 AILLVDYSNLGVREGKSLRQSLADAGAVRLRPIVMTTLAMIFGMLPTALGLGEGGAQRAP 991 Query: 1013 LGRAVIGGLLLATVSTLFFVPVV------FAGVHQR 1042 + A+IGGL+ +T+ +L FVPVV FAG +R Sbjct: 992 MAHAIIGGLISSTLLSLVFVPVVLTYLDAFAGRVRR 1027 >aq_786 [V] COG0841 Cation/multidrug efflux pump Aae Aquifex aeolicus Length = 1000 Score = 369 bits (947), Expect = e-101, Method: Compositional matrix adjust. Identities = 287/1048 (27%), Positives = 496/1048 (47%), Gaps = 70/1048 (6%) Query: 3 MVALALRRPYTFIVMALLIVLATPLTLKNMATDIFPEINIPVVSVIWNYNGLSAQEMGQR 62 M + RP T ++ L V +LK + D P++ PVV + +Y G + Sbjct: 1 MQKFFIERPVTAFMLMLSFVFLGLYSLKLVPIDRLPDVEFPVVRISADYPGADPYVVDTN 60 Query: 63 IAAQNERGLTTVVSDIEHIESQSLAGVAVIKVFFQPKANIQTAIAQVVASVQSQLRQLPP 122 + E ++TV S IE I S+S G A + V F +I A +V ++Q +R+ P Sbjct: 61 VTRIIEEAVSTV-SGIESIISRSYPGFASVVVTFTLDKDIDVATQEVSNAIQRAMRRFPK 119 Query: 123 GITPPLVIKYSASSIPVMQLALSSPTLPEQTVFDTAVQTLRPQLITIPGVAVPFPYGGKT 182 G+ PP V+K S P+M L L S T Q + A + ++ +L + GV G + Sbjct: 120 GVEPPTVVKVDTSVAPIMVLLLYSDTADYQRLTYYADKVIKRELEKLYGVGSVSLGGFRD 179 Query: 183 RLISVDLDTPALQSRGLSPIDVVNAINTQNLILPSGTAKFGGTEYSVKLNGSPEAVAGLN 242 ++ V L L L+P+DV+ I+ + +P+G EY ++L G + L+ Sbjct: 180 NVLWVRLKVSELYGYELTPLDVLREIDKNHQDIPAGNVYGKRREYILRLYGKFKTPEELS 239 Query: 243 ELPVRTANGATIYLKDVANVRDGFSPQTNVVRQDGARGVLLSILKNGGASTLDIVDNLRK 302 L ++ + L DVA V G + ++ R +G R V L + K +T+ ++D ++ Sbjct: 240 NLYIK----ENLRLGDVARVYFGEDEERSLARFNGNRAVALLVFKQAKVNTVRVIDEIKS 295 Query: 303 LLPTAAQTLPEDIKITPLFDQSLFVKAAVTGVISEALIAAGLTAAMVLLFLGNWRSTLII 362 + + LP DIK+ FD S++VK ++ E +I LTA V LFLGN R TL+ Sbjct: 296 RMEFFRELLPPDIKLDYTFDASVYVKESIRAAFEEIIIGVFLTAFTVYLFLGNLRLTLVP 355 Query: 363 GLTIPLSIMAAILMLAALGETLNLMTLGGLALSVGILVDQAIVTIENIERHLHLGKPLHD 422 IP++I+ I L LG +LN +TL LA++VGI++D AIV +E+I R G P + Sbjct: 356 VFAIPVTILGTIFFLYQLGYSLNTITLLALAVAVGIVIDDAIVVMESIHRRREEGLPPFE 415 Query: 423 AIIVGAGEIGVPAFVATLCICIVFVPMFFLSGVARFLFVPLAEAVVFAMAASYLLSRTLV 482 A + G + +T + +VF+P+ FL GV A ++ A+ SYL++ T Sbjct: 416 AGVKGTRVVMFALLASTSVLIVVFLPVVFLKGVLGTFLKNFALTLIIAIGLSYLVAITFT 475 Query: 483 PTLVMLLMGSHGQVDSAKQSLLQRLYRAFDNRFER-----VRHGYTLVLSSLLAHRRRFA 537 P+ + L+ +++ +LY+ F+ F++ + H + ++L S Sbjct: 476 PSATVRLITQR-----PRENFFMKLYKRFEGSFDKALRFSLDHKFIVLLLSFF------- 523 Query: 538 LGFLGFCLLSCLLYPFLGRDFFPNVDGGQIRLHMRMPTGTRIEETARAADEVERVIRSLI 597 F LS L+P + ++F P+VD G+ + MRMP GT E A EVER+ Sbjct: 524 -----FVGLSVYLFPKVKKEFVPHVDEGRFMVRMRMPVGTSFERVKEKAKEVERI----- 573 Query: 598 PASELETILDNLGVPNSGINLSYSNAGTIGTLDGEILMALKE-GHRPTEELV-SLLREQL 655 +L N + G+ + G G + LKE RP + +V S +R +L Sbjct: 574 -------LLKNPHIAKVGMVVGEGVGGAGVH-SGLFFVYLKERSQRPHQMVVMSEVRREL 625 Query: 656 PRRFPGIEFFFQPADIVTQILNFGLPAA----IDVQFT--GPNMEANARLAAELTKQIRQ 709 ++ +P G+ A+ D+Q+ G +E ++A + + Sbjct: 626 S-ELKNVKVSVEPPH--------GIGASAGRTTDLQYIVRGERIEVLKKIAKSMEEHFSN 676 Query: 710 IPGAVDAHVHQRLDGPSLDLRMDRTRLQQFGLSAANVGQNLLIALSGSSQTQPAFWLNPN 769 + G D L P + + + R +L G+S ++G L ++L + L Sbjct: 677 VEGFRDVDTSLELSAPYVKISVKREKLSHLGVSVEDLG--LTLSLLFGKYRVGTYELGSE 734 Query: 770 NGVVYSIAVQSPQYQVDSLDALLNIPVGAGANAATPPQLLGNLVDVHAGRQMAVASRYNI 829 + Y +++ + V + L + + A P + L+D +RYN Sbjct: 735 S---YDFYIKAEEDFVKEIHNLNRVYIRARNGELIP---ITELIDFSIEAGPFSLTRYNR 788 Query: 830 SPAIDVYVSVQGTDLASVAGKVAKLVEE-IKPKLARGSQVVIRGQVETMQSSFIGLGVGL 888 + Y +++G DLA+ LVE+ +K L G G+V+ + +F G + L Sbjct: 789 QYSFVFYANLEGIDLATARS----LVEDWLKKNLPFGYTYDTAGRVKEFKKAFSGFVLSL 844 Query: 889 AMAIVLVYLLVVVNFQSWIDAAIIIAALPAALAGIAWMLFLTGTTLSVPALTGAIMTMGV 948 AM+++ VY+++ F+S ++ +P + G+ ++LT T+L+V + G I+ +G+ Sbjct: 845 AMSLIGVYMILASLFESLKHPFTVLLMVPLSALGVFGFMYLTDTSLNVSSYFGIILLVGI 904 Query: 949 ATANSILIVAFARQRREEGATPLASALEAGSTRIRPVLMTALAMIIGMIPMALGLGEGAE 1008 +++L + Q R+EG + LEA R+RP+LMT + ++ ++P+ALGL G+E Sbjct: 905 IVRDAVLFIERIIQLRKEGYAVREAILEARRERLRPILMTTITVVSALLPVALGLTAGSE 964 Query: 1009 QNAPLGRAVIGGLLLATVSTLFFVPVVF 1036 Q PL AVIGG+ +LF +PV++ Sbjct: 965 QRKPLAIAVIGGIASGLPLSLFLLPVLY 992 >BH3816 [V] COG0841 Cation/multidrug efflux pump Bha Bacillus halodurans Length = 1093 Score = 350 bits (897), Expect = 2e-95, Method: Compositional matrix adjust. Identities = 298/1069 (27%), Positives = 507/1069 (47%), Gaps = 77/1069 (7%) Query: 3 MVALALRRPYTFIVMALLIVLATPLTLKNMATDIFPEINIPVVSVIWNYNGLSAQEMGQR 62 M ++RRP IV ++ +L ++ N+ + P++N P+ +V +Y G SA+E+ + Sbjct: 1 MTQFSIRRPVFTIVGMIIFLLVGGISYVNLPLQLTPDLNPPIGAVTASYPGASAEEVSEN 60 Query: 63 IAAQNERGLTTVVSDIEHIESQSLAGVAVIKVFFQPKANIQTAIAQVVASVQSQLRQLPP 122 + E L+T S + I SQS+ G A+I + F NI +++++ LP Sbjct: 61 VTRILEDELSTT-SGLNKITSQSMEGSAIIILEFGWTTNIDDVENDIISTINRA--DLPD 117 Query: 123 GITPPLVIKYSASSIPVMQLALSSPTLPEQTVFD--TAVQTLRPQLITIPGVAVPFPYGG 180 G + P +K+ S+ P+M+L ++S T + + D A+ L ++ + GVA +G Sbjct: 118 GASNPSFLKFDPSAFPIMELVVTSDT---EAISDISEALDELEREIGRVEGVASVSSHGR 174 Query: 181 KTRLISVDLDTPALQSRGLSPIDVVNAINTQNLILPSGTAKFGGTEYSVKLNGSPEAVAG 240 + V +D AL+ L+ DVV+ I ++ LP GT G + + + +AV Sbjct: 175 LMERVEVTIDDEALEEANLTQQDVVDVIEANDISLPGGTISDGDRSLTTRTIRTLDAVET 234 Query: 241 LNEL--PVRTANGATIYLKDVANVRDGFSPQTNVVRQDGARGVLLSILKNGGASTLD--- 295 + +L + T G + L DVA+V +T + R + V SI+K A+++D Sbjct: 235 IEDLVLTIDTQTGDDVLLSDVADVSISLEDETVITRANNDPAVQFSIMKEDAANSVDVSV 294 Query: 296 -IVDNLRKLLPTAAQTLPEDIKITPLFDQSLFVKAAVTGVISEALIAAGLTAAMV--LLF 352 I + L +LL Q +D+ L+D+ F+ A+ V+ ALIA G T AMV LF Sbjct: 295 AITERLDELLE---QDRFDDVSAFVLYDEGDFILEAINNVLV-ALIA-GATMAMVVLFLF 349 Query: 353 LGNWRSTLIIGLTIPLSIMAAILMLAALGETLNLMTLGGLALSVGILVDQAIVTIENIER 412 L N+++ LIIG+ IP S++ L +LN+++LGGLAL +G+LVD +IV IENI R Sbjct: 350 LRNFKTPLIIGIAIPFSVIVTFAFLYFTNVSLNILSLGGLALGIGMLVDNSIVVIENIYR 409 Query: 413 HLHLGKPLHDAIIVGAGEIGVPAFVATLCICIVFVPMFFLSGVARFLFVPLAEAVVFAMA 472 HL +GK A + G E+ +TL VFVP+ FL+G+ LF+ A V ++ Sbjct: 410 HLSMGKEPKQAALEGTREVRGAITASTLTTISVFVPILFLTGLVGELFIQFALTVSLSLF 469 Query: 473 ASYLLSRTLVPTLVMLLMGSHGQVDSAKQSLLQRLYRAFDNRFERVRHGYTLVLSSLLAH 532 AS L++ TLVP LM S RL R F E R +L+ + Sbjct: 470 ASLLVAITLVP-----LMAS-------------RLLRKFQQNEEAKRQQSRFILT--IER 509 Query: 533 RRRFALGFLGFCLLSCLLY--------PFLGRDFFPNVDGGQIRLHMRMPTGTRIEETAR 584 ++AL L++ LL +G DF ++D G + + + GT +E R Sbjct: 510 SIKWALRHRAMVLIATLLLFVGGLYGLSTVGVDFLEDMDEGLMVVEIEHEPGTSLE---R 566 Query: 585 AADEVERVIRSLIPASELETILDNLGVPNSGINLSYSNAGTIGTLDGEILMAL---KEGH 641 + VE + + L SE+E + G + + N+ +G++ L + Sbjct: 567 TRETVEAIEQKLEDYSEIENFVSTSGARGTNVGRRDGNS-----YEGQVQATLVPSSDRD 621 Query: 642 RPTEELVSLLREQLPRRFPGIEFFFQPADIVTQILNFGLPAAIDVQFTGPNMEANARLAA 701 T E V ++ + R E P L P + + + + Sbjct: 622 LTTLEFVESIKRDVERVDSDAEINVSPLS-----LQGSEPNTLTFYLSDSDPDRLEEATE 676 Query: 702 ELTKQIRQIPGAVDAHVHQRLDGPSLDLRMDRTRLQQFGLSAANVGQNLLIALSGSSQTQ 761 L +++ + + + + P L +D ++ GL A V Q + G + T Sbjct: 677 ALEEELLERNEVTNLELSIDVTTPEYQLLIDEEAARENGLVPAQVAQFVYDVTLGQTVTT 736 Query: 762 PAFWLNPNNGVVYSIAVQSPQYQVDSLDALLNIPVGAGANAATPPQLLGNLVDVHAGRQM 821 L +N + Y + V+ +DSL+ + + + P LG++V + G Sbjct: 737 ----LEIDNDL-YDLFVRYHPDVLDSLETMEELTIRNNEGVYVP---LGDVVTIEEGEGP 788 Query: 822 AVASRYNISPAIDVYVSVQGT-DLASVAGKVAKLVEEIKPKLARGSQVVIRGQVETMQSS 880 A +R A++ V+ + L ++ V +V+E ++ G E ++++ Sbjct: 789 ATINRIEQRDAVEFTVTYDSSLSLGDISSIVLDIVDE--QNFEDTTEFAFTGDQEALETA 846 Query: 881 FIGLGVGLAMAIVLVYLLVVVNFQSWIDAAIIIAALPAALAGIAWMLFLTGTTLSVPALT 940 L +A+V V+L++ F+S+ +++ +LP + G++ L +TGT+ SV A Sbjct: 847 MADLTGAFMLAVVFVFLVMAAQFESFRFPFVVMFSLPLVMIGVSLALLVTGTSFSVMAGI 906 Query: 941 GAIMTMGVATANSILIVAFARQRREEGATPLASALEAGSTRIRPVLMTALAMIIGMIPMA 1000 G I+ G+ N+I+IV + Q + GAT + +EA R RPVLMTAL I+G++P+A Sbjct: 907 GMIILAGIVVNNAIVIVDYMNQLKASGATSYEAIVEAVKQRTRPVLMTALTTILGVLPLA 966 Query: 1001 LGLGEGAEQNAPLGRAVIGGLLLATVSTLFFVPVVFAGVHQRLARRAER 1049 L LGEG E P+G VIGGL+ T TLF +PV+++ + + RR + Sbjct: 967 LALGEGTEMQRPIGLTVIGGLISGTFLTLFVIPVIYS-LFDKDTRRLNK 1014 >AGl494 [V] COG0841 Cation/multidrug efflux pump Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 1048 Score = 343 bits (881), Expect = 1e-93, Method: Compositional matrix adjust. Identities = 302/1046 (28%), Positives = 518/1046 (49%), Gaps = 47/1046 (4%) Query: 13 TFIVMALLIVLATPLTLKNMATDIFPEINIPVVSVIWNYNGLSAQEMGQRIAAQNERGLT 72 T +++ALL++ A +L+ + D +P +++PVV V+ +Y G + + + + E L Sbjct: 15 TMMMVALLVMGA--FSLQRLGLDQYPNVDVPVVVVVTSYPGATPETVEMEVTRPVEDALN 72 Query: 73 TVVSDIEHIESQSLAGVAVIKVFFQPKANIQTAIAQVVASVQSQLRQLPPGITPPLVIKY 132 + ++ + S S G +V+ F+ + A +V + + P P++ ++ Sbjct: 73 AI-GGLDEVTSTSYEGRSVVVAKFKLEVQSSAAAQEVRDKIAAIEANFPEDTKKPVISRF 131 Query: 133 SASSIPVMQLALSSPTLPEQTVFDTAVQTLRPQLITIPGVAVPFPYGGKTRLISVDLDTP 192 ++ P++ LA+SS +L + A Q + QL T+ G+ GG+ R I V +D Sbjct: 132 DPAAEPILSLAISSTSLDVPALATLAEQKVVRQLTTVAGIGQATLVGGRKRQIDVTIDET 191 Query: 193 ALQSRGLSPIDVVNAINTQNLILPSGTAKFGGTEYSVKLNGSPEAVAGLNELPVRTANGA 252 +++ G+ +VV A+ N P+G+ +E ++++ E L ++ V G Sbjct: 192 RMRALGIGVNEVVTALRAGNSNSPAGSVVDPVSERTIQIQSRIEEPEALLDMVVARRGGV 251 Query: 253 TIYLKDVANVRDGFSPQTNVVRQDGARGVLLSILKNGGASTLDIVDNLRKLLPT-AAQTL 311 I L+DVA + +G + N +G + + I+K A+T+ +V ++RK L A+ Sbjct: 252 AILLRDVATLSEGAADAENRAIYNGQTALAIDIVKVQDANTVQVVSDVRKRLDALNAELS 311 Query: 312 PEDIKITPLFDQSLFVKAAVTGVISEALIAAGLTAAMVLLFLGNWRSTLIIGLTIPLSIM 371 P++I++ + D S+ ++ +VT V + + A L A+V LFL +WRST+I GLT+P++I+ Sbjct: 312 PQNIQLRIVTDSSIPIQESVTQVQTTLIEGAALAVAIVFLFLNSWRSTVITGLTLPIAII 371 Query: 372 AAILMLAALGETLNLMTLGGLALSVGILVDQAIVTIENIERHLHLGKPLHDAIIVGAGEI 431 + ++ LG TLN ++L L LS+GILVD AIV ENI RHLH+GK A + G GEI Sbjct: 372 GTLTVVDFLGFTLNTLSLLALTLSIGILVDDAIVVRENITRHLHMGKSHLRAALDGTGEI 431 Query: 432 GVPAFVATLCICIVFVPMFFLSGVARFLFVPLAEAVVFAMAASYLLSRTLVPTLVMLLMG 491 G+ T I VF+P+ F+ G+ F V A+ S ++ TL P L + Sbjct: 432 GLAVIATTATIVAVFLPVAFMDGIVGRFFYQFGVTVSAAVLISLFVAFTLDPMLSSVWYD 491 Query: 492 SHGQVDSAKQSLLQRLYRAFDNRFERVRHGYTLVLSSLLAHRRRFALGFLGFCLLSCLLY 551 Q D AK+ + RL FD+ FE + Y + L HR L G + S + Sbjct: 492 PDAQAD-AKRGPIGRLIARFDHGFEWMAGQYRHAIDWTLRHRLVTLLVTAGIFIGSLFMV 550 Query: 552 PFLGRDFFPNVDGGQIRLHMRMPTGTRIEETARAADEVERVIRSLIPASELETILDNLGV 611 P +G +F P+ D G+ ++++ P G+ ++ T +V++ +R E+E + + Sbjct: 551 PLVGTEFVPDADEGRFQINLTAPVGSSLDYTTAKLQQVKKALREF---PEVEMLYSTI-- 605 Query: 612 PNSGINLSYSNAGTIGTLDGEILMALKEGHRPTEELVSL---LREQLPRRFPGIEFFFQP 668 N+G G G IL+ L + +SL +R++L PGIE Sbjct: 606 -NTG--------GAAGKHRAAILVGLVPLSAREQTPLSLAEPVRKRLSA-IPGIEI---- 651 Query: 669 ADIVTQILNFGL---PAAIDVQFTGPNMEANARLAAELTKQIRQIPGAVDAHVHQRLDGP 725 IL GL + + + G + ++A L + +++IPG V+ + Sbjct: 652 -----NILQNGLGGGESPVQLSILGDDRAVLEKIANGLVEDMKKIPGLVEVTSSTKDVTS 706 Query: 726 SLDLRMDRTRLQQFGLSAANVGQNLLIALSGSSQTQPAFWLNPNNGVVYSIAVQSP-QYQ 784 L +R+ G++ A++ L + G ++ W + + G Y I V+ P + + Sbjct: 707 ILSVRLKPAAASDLGIARADLAAALSALIGGEDVSK---WTDAH-GNSYDIVVRLPVERR 762 Query: 785 VDS--LDALLNIPVGAGANAATPPQLLGNLVDVHAGRQMAVASRYNISPAIDVYVSVQGT 842 D+ L L+ GAN A L + D+ A R++ I V ++ G Sbjct: 763 SDAARLGELMITTGRTGANGAPLMVRLDQVADIGTVAAPAEIRRFDNRREILVSANITGR 822 Query: 843 DLASVAGKVAKLVEEIKPKLARGSQVVIRGQVETMQSSFIGLGVGLAMAIVLVYLLVVVN 902 L V + L L G ++ G+ ETMQ + +G L+MAI+ +Y+++ Sbjct: 823 TLGDVTETLQGLTA--SRDLPAGYRIRFGGEAETMQETVGHMGTALSMAIIFIYIVLASQ 880 Query: 903 FQSWIDAAIIIAALPAALAGIAWMLFLTGTTLSVPALTGAIMTMGVATANSILIVAFARQ 962 F S++ I+ +LP +L G+ L + G+T+++ +L G IM MG+ T N IL+V FA + Sbjct: 881 FGSFLQPLAIMVSLPLSLIGVLLGLMVAGSTINMFSLIGFIMLMGLVTKNGILLVDFANR 940 Query: 963 RREEGATPLASALEAGSTRIRPVLMTALAMIIGMIPMALGLGEGAEQNAPLGRAVIGGLL 1022 R G T + AG R RP++MT LAMI GMIP+ L +G G Q AP+ AV+GGL+ Sbjct: 941 ERRRGLTLNEALANAGVIRFRPIIMTTLAMIFGMIPLGLAVGGGGAQRAPMAHAVVGGLI 1000 Query: 1023 LATVSTLFFVPVVFA---GVHQRLAR 1045 +T+ TL VPV+ + + +R AR Sbjct: 1001 SSTLLTLIVVPVILSYIDSITRRFAR 1026