BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0033.0061.p (409 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AGc2694 [GEPR] COG0477 Permeases of the major facilitator superf... 261 2e-69 Rv2456c [GEPR] COG0477 Permeases of the major facilitator superf... 241 2e-63 MT2531 [GEPR] COG0477 Permeases of the major facilitator superfa... 241 2e-63 >AGc2694 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 498 Score = 261 bits (667), Expect = 2e-69, Method: Compositional matrix adjust. Identities = 158/361 (43%), Positives = 217/361 (60%), Gaps = 3/361 (0%) Query: 11 LSRLNFFLADVRDGLGPFLGVFLMGHGWAADDIGYVMTLGGIAGMLATTPAGALTDAVRA 70 L+ LNFFLAD RDGLGPFL FL GW++ +G + T+GG+ G+LAT GAL D Sbjct: 105 LAALNFFLADARDGLGPFLDAFLATQGWSSLSLGMIATVGGLVGLLATPLCGALVDGTTW 164 Query: 71 KRLVVGIGSVLVVAGSLLLLVSPSFTITAVSQVGTGIVGAIIGPAIAGLTLGIVGQQGLP 130 KR+++ I VLV G+L+ L+ P I Q+ T +VGA++GPA+AGLTLG+VG++ Sbjct: 165 KRMLIAIPVVLVTIGALITLIFPDAWIVWTGQIMTAVVGAVVGPALAGLTLGLVGERLFS 224 Query: 131 SQLGKNEAWNHGGNVFSAALAGALGYFWGLPAVFVLMAVMAVASLVCLSRIRPEDIDHDV 190 +Q+ +NE WNHGGN S + F+G+ + LM + A +LV + I P IDH V Sbjct: 225 NQISRNEFWNHGGNFASLFATYVVVTFFGMNGIIGLMLLTAAGALVATAAIDPARIDHKV 284 Query: 191 ARGLDPERAADQPQVSTWRVLAGSRPLMLLALAMMLFHLGNAAMLPLLSQSVVSRGNADP 250 ARGL ++ +P S VL R L+ LA+ +++FH GNA M L++Q P Sbjct: 285 ARGLAEDKG--EPGPSGINVLLHERGLIFLAIILLVFHFGNAPMGRLIAQDFAIELQT-P 341 Query: 251 ALYTALTVIVAQLVMIPTALFAGRFADRKGYWLLITVALLALPVRGLVAGVWDSAWALLP 310 TA+ VAQ MI A A R G + VAL ALP+RGL+A + W + P Sbjct: 342 FRTTAIITGVAQFAMIFVAAMAPWLIRRFGLSTVFIVALAALPIRGLLASAFTDFWVIFP 401 Query: 311 VQMLDGVGAGLLGVALPGSVARILQGSGHINIGLGAVTTIQSIGAAMSPALAGVVAKHYG 370 VQ LDGVGAGLLG+ P +V RIL+G+G N+GL +V +Q IGA++S +AG + G Sbjct: 402 VQFLDGVGAGLLGIVTPVAVERILKGTGRFNVGLASVMMVQGIGASLSNVVAGWLVTKGG 461 Query: 371 Y 371 Y Sbjct: 462 Y 462 >Rv2456c [GEPR] COG0477 Permeases of the major facilitator superfamily Mtu Mycobacterium tuberculosis H37Rv Length = 418 Score = 241 bits (616), Expect = 2e-63, Method: Compositional matrix adjust. Identities = 157/373 (42%), Positives = 223/373 (59%), Gaps = 1/373 (0%) Query: 11 LSRLNFFLADVRDGLGPFLGVFLM-GHGWAADDIGYVMTLGGIAGMLATTPAGALTDAVR 69 L LNF LADVRDGLGP+L ++L+ H W IG+VM +GGIA ++A TP GAL D Sbjct: 16 LDLLNFSLADVRDGLGPYLSIYLLLIHDWDQASIGFVMAVGGIAAIVAQTPIGALVDRTT 75 Query: 70 AKRLVVGIGSVLVVAGSLLLLVSPSFTITAVSQVGTGIVGAIIGPAIAGLTLGIVGQQGL 129 AKR +V G+VLV A ++ + + +V Q TGI ++ PA+A +TLG VG Q Sbjct: 76 AKRALVVAGAVLVTAAAVAMPLFAGLYSISVLQAVTGIASSVFAPALAAITLGAVGPQFF 135 Query: 130 PSQLGKNEAWNHGGNVFSAALAGALGYFWGLPAVFVLMAVMAVASLVCLSRIRPEDIDHD 189 ++G+NEA+NH GN +A GAL YF+G VF ++A MA+ S++ RI P+ +DHD Sbjct: 136 ARRIGRNEAFNHAGNASAAGATGALAYFFGPVVVFWVLAGMALISVLATLRIPPDAVDHD 195 Query: 190 VARGLDPERAADQPQVSTWRVLAGSRPLMLLALAMMLFHLGNAAMLPLLSQSVVSRGNAD 249 +ARG+D PQ S + VLA +R L++ A++ FH NAAMLPL+ + + + Sbjct: 196 LARGMDHAPGEPHPQPSRFTVLAHNRELVIFGAAVVAFHFANAAMLPLVGELLALHNRDE 255 Query: 250 PALYTALTVIVAQLVMIPTALFAGRFADRKGYWLLITVALLALPVRGLVAGVWDSAWALL 309 + ++ AQ+VM+P A G AD G + V L RG + + D+++ L+ Sbjct: 256 GTALMSSCIVAAQVVMVPVAYVVGTRADAWGRKPIFLVGFAVLTARGFLYTLSDNSYWLV 315 Query: 310 PVQMLDGVGAGLLGVALPGSVARILQGSGHINIGLGAVTTIQSIGAAMSPALAGVVAKHY 369 VQ+LDG+GAG+ G P V + G+GH NI LGAVTT IGAA+S +AG + Sbjct: 316 GVQLLDGIGAGIFGALFPLVVQDVTHGTGHFNISLGAVTTATGIGAALSNLVAGWIVVVA 375 Query: 370 GYGAAFAALTGIA 382 GY AAF +L +A Sbjct: 376 GYDAAFMSLGALA 388 >MT2531 [GEPR] COG0477 Permeases of the major facilitator superfamily MtC Mycobacterium tuberculosis CDC1551 Length = 418 Score = 241 bits (616), Expect = 2e-63, Method: Compositional matrix adjust. Identities = 157/373 (42%), Positives = 223/373 (59%), Gaps = 1/373 (0%) Query: 11 LSRLNFFLADVRDGLGPFLGVFLM-GHGWAADDIGYVMTLGGIAGMLATTPAGALTDAVR 69 L LNF LADVRDGLGP+L ++L+ H W IG+VM +GGIA ++A TP GAL D Sbjct: 16 LDLLNFSLADVRDGLGPYLSIYLLLIHDWDQASIGFVMAVGGIAAIVAQTPIGALVDRTT 75 Query: 70 AKRLVVGIGSVLVVAGSLLLLVSPSFTITAVSQVGTGIVGAIIGPAIAGLTLGIVGQQGL 129 AKR +V G+VLV A ++ + + +V Q TGI ++ PA+A +TLG VG Q Sbjct: 76 AKRALVVAGAVLVTAAAVAMPLFAGLYSISVLQAVTGIASSVFAPALAAITLGAVGPQFF 135 Query: 130 PSQLGKNEAWNHGGNVFSAALAGALGYFWGLPAVFVLMAVMAVASLVCLSRIRPEDIDHD 189 ++G+NEA+NH GN +A GAL YF+G VF ++A MA+ S++ RI P+ +DHD Sbjct: 136 ARRIGRNEAFNHAGNASAAGATGALAYFFGPVVVFWVLAGMALISVLATLRIPPDAVDHD 195 Query: 190 VARGLDPERAADQPQVSTWRVLAGSRPLMLLALAMMLFHLGNAAMLPLLSQSVVSRGNAD 249 +ARG+D PQ S + VLA +R L++ A++ FH NAAMLPL+ + + + Sbjct: 196 LARGMDHAPGEPHPQPSRFTVLAHNRELVIFGAAVVAFHFANAAMLPLVGELLALHNRDE 255 Query: 250 PALYTALTVIVAQLVMIPTALFAGRFADRKGYWLLITVALLALPVRGLVAGVWDSAWALL 309 + ++ AQ+VM+P A G AD G + V L RG + + D+++ L+ Sbjct: 256 GTALMSSCIVAAQVVMVPVAYVVGTRADAWGRKPIFLVGFAVLTARGFLYTLSDNSYWLV 315 Query: 310 PVQMLDGVGAGLLGVALPGSVARILQGSGHINIGLGAVTTIQSIGAAMSPALAGVVAKHY 369 VQ+LDG+GAG+ G P V + G+GH NI LGAVTT IGAA+S +AG + Sbjct: 316 GVQLLDGIGAGIFGALFPLVVQDVTHGTGHFNISLGAVTTATGIGAALSNLVAGWIVVVA 375 Query: 370 GYGAAFAALTGIA 382 GY AAF +L +A Sbjct: 376 GYDAAFMSLGALA 388