BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0033.0020.p (296 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0746 [Q] COG2175 Probable taurine catabolism dioxygenase Rso ... 370 e-102 PA2310 [Q] COG2175 Probable taurine catabolism dioxygenase Pae P... 357 2e-98 PA3935 [Q] COG2175 Probable taurine catabolism dioxygenase Pae P... 191 2e-48 tauD [Q] COG2175 Probable taurine catabolism dioxygenase Eco Esc... 187 2e-47 ZtauD [Q] COG2175 Probable taurine catabolism dioxygenase EcZ Es... 187 2e-47 >RSc0746 [Q] COG2175 Probable taurine catabolism dioxygenase Rso Ralstonia solanacearum Length = 301 Score = 370 bits (950), Expect = e-102, Method: Compositional matrix adjust. Identities = 182/284 (64%), Positives = 222/284 (78%), Gaps = 2/284 (0%) Query: 14 QHFEIRPF-DAPLGAEIVGLDLNLPVSAQQLARIRGALVEH-GVVVFREQRITPQQHIDF 71 + F++R APLGAEI+GL+ +S +A IR A + H G++VFR+ R+ P+ +DF Sbjct: 17 RRFQVRRLPGAPLGAEILGLNDAAGLSDADVAAIRQAWLAHDGLLVFRDVRLAPRAQVDF 76 Query: 72 SRRFGPLQVHVLNRFHLAGHPEILIVSNVVENGKPIGLVDAGADWHSDLSYMPKPSLGAL 131 SRRFGPLQVHVLN+FHL HPEIL+VSNVVENGKPIGL DAG DWHSDLSY P+PSLG+L Sbjct: 77 SRRFGPLQVHVLNQFHLPAHPEILVVSNVVENGKPIGLGDAGRDWHSDLSYRPRPSLGSL 136 Query: 132 LHSQELPAERGDTLYANTAAAWDSLPAALKTQLEGKRAVHSYVYRYERLRKLSPWRQPLT 191 L ++ELP GDTL+AN A+++LPA LK +EG+RAVHSYVYRYERLR LS WR PLT Sbjct: 137 LLARELPQAGGDTLFANMVRAYETLPAELKHSIEGRRAVHSYVYRYERLRALSAWRPPLT 196 Query: 192 QQQIDEVPPVEHPVVITHPESGRKILFVSEGFTSHIIGIPRDESDALLKELHAHITRPEN 251 Q Q D VPPV+HPVV THPE+GR+ LFV+EGFTS I+G+P DES +L +L AH RP+N Sbjct: 197 QAQRDAVPPVDHPVVRTHPETGRRALFVNEGFTSRILGLPEDESTTVLAQLFAHSIRPDN 256 Query: 252 VYTHHWQAHDMVFWDNRSTQHYAAITPQHLRRTLYRTTVEGDVP 295 +YTH WQ DM+FWDNRST H+A P RRTL+RTT+EGDVP Sbjct: 257 IYTHRWQPGDMLFWDNRSTLHFAPGCPDTHRRTLHRTTIEGDVP 300 >PA2310 [Q] COG2175 Probable taurine catabolism dioxygenase Pae Pseudomonas aeruginosa Length = 295 Score = 357 bits (916), Expect = 2e-98, Method: Compositional matrix adjust. Identities = 174/280 (62%), Positives = 207/280 (73%) Query: 16 FEIRPFDAPLGAEIVGLDLNLPVSAQQLARIRGALVEHGVVVFREQRITPQQHIDFSRRF 75 +IR DA GAE++GLDL LP++A+ RI A ++H V+VFREQRITP Q I FSRRF Sbjct: 15 LQIRALDAAFGAEVLGLDLGLPLAAEDFRRIHRAHLDHHVLVFREQRITPAQQIAFSRRF 74 Query: 76 GPLQVHVLNRFHLAGHPEILIVSNVVENGKPIGLVDAGADWHSDLSYMPKPSLGALLHSQ 135 G LQ+HVL +F L GHPEILIVSN+VENG+PIGL DAG WHSDLSY PSLG++LH+Q Sbjct: 75 GELQIHVLKQFLLPGHPEILIVSNIVENGQPIGLGDAGKFWHSDLSYKELPSLGSMLHAQ 134 Query: 136 ELPAERGDTLYANTAAAWDSLPAALKTQLEGKRAVHSYVYRYERLRKLSPWRQPLTQQQI 195 ELP E GDTL+A+ AWDSLP AL+ +EG+ A HSY RY R WR L+ Q+ Sbjct: 135 ELPEEGGDTLFADMHKAWDSLPEALRKAIEGRTAAHSYTARYSEPRFEGNWRPTLSAAQL 194 Query: 196 DEVPPVEHPVVITHPESGRKILFVSEGFTSHIIGIPRDESDALLKELHAHITRPENVYTH 255 EV V HP+V THPESGRK LFVSEGFT+ I+G+P DES LL EL+AH RPE++Y H Sbjct: 195 AEVREVVHPIVRTHPESGRKALFVSEGFTTRIVGLPADESAQLLAELYAHSVRPEHIYRH 254 Query: 256 HWQAHDMVFWDNRSTQHYAAITPQHLRRTLYRTTVEGDVP 295 WQAHD+VFWDNRS H A P HLRR LYRTT++GD P Sbjct: 255 RWQAHDLVFWDNRSLIHLAGGCPAHLRRKLYRTTIQGDAP 294 >PA3935 [Q] COG2175 Probable taurine catabolism dioxygenase Pae Pseudomonas aeruginosa Length = 277 Score = 191 bits (484), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 110/279 (39%), Positives = 162/279 (58%), Gaps = 8/279 (2%) Query: 18 IRPFDAPLGAEIVGLDLNLPVSAQQLARIRGALVEHGVVVFREQRITPQQHIDFSRRFGP 77 I+P LGA + G+DL P+ I AL+EH V+ FR+Q + P+ F+ RFG Sbjct: 5 IQPISPALGAIVSGIDLGAPLDDTGQRAIEQALLEHQVLFFRDQSLEPRSQARFAARFGD 64 Query: 78 LQVHVLNRFHLAGHPEILIVSNVVENGKPIGLVDAGADWHSDLSYMPKPSLGALLHSQEL 137 L +H + + PE++++ V + V A WH+D++++ P+LGA+L +++L Sbjct: 65 LHIHPIYP-SVPEQPEVIVLDTAVTD------VRDNAIWHTDVTFLETPALGAVLAAKQL 117 Query: 138 PAERGDTLYANTAAAWDSLPAALKTQLEGKRAVHSYVYRYERLR-KLSPWRQPLTQQQID 196 P GDTL+A++ AA+++L A L+ L+G A H + R R ++ ++ Sbjct: 118 PPYGGDTLWASSTAAYEALSAPLRRLLDGLTATHDIGKSFPRERFGVTEADLARLEEARL 177 Query: 197 EVPPVEHPVVITHPESGRKILFVSEGFTSHIIGIPRDESDALLKELHAHITRPENVYTHH 256 + PP HPVV THP +GRK LFVS+GFT+ I + ESDALLK L AH TRPE Sbjct: 178 KNPPRSHPVVRTHPVTGRKGLFVSDGFTTRINELEPAESDALLKFLFAHATRPEFTVRWR 237 Query: 257 WQAHDMVFWDNRSTQHYAAITPQHLRRTLYRTTVEGDVP 295 WQ +D+ FWDNR TQHYA + RR ++R T+ GD P Sbjct: 238 WQENDVAFWDNRVTQHYAVDDYRPQRRVMHRATILGDKP 276 >tauD [Q] COG2175 Probable taurine catabolism dioxygenase Eco Escherichia coli K12 Length = 283 Score = 187 bits (476), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 109/288 (37%), Positives = 162/288 (56%), Gaps = 18/288 (6%) Query: 14 QHFEIRPFDAPLGAEIVGLDLNLPVSAQQLARIRGALVEHGVVVFREQRITPQQHIDFSR 73 + I P +GA+I G DL P+S Q ++ A++ H VV R+Q ITPQQ ++ Sbjct: 3 ERLSITPLGPYIGAQISGADLTRPLSDNQFEQLYHAVLRHQVVFLRDQAITPQQQRALAQ 62 Query: 74 RFGPLQVHVLNRFHLAGHPEILIVSNVVENGKPIGLVDAGADWHSDLSYMPKPSLGALLH 133 RFG L +H + H G EI+++ N P +WH+D++++ P GA+L Sbjct: 63 RFGELHIHPVYP-HAEGVDEIIVLD--THNDNPPD----NDNWHTDVTFIETPPAGAILA 115 Query: 134 SQELPAERGDTLYANTAAAWDSLPAALKTQLEGKRAVHSY-----VYRYERLRKL-SPWR 187 ++ELP+ GDTL+ + AA+++L + L G RA H + Y+Y + + WR Sbjct: 116 AKELPSTGGDTLWTSGIAAYEALSVPFRQLLSGLRAEHDFRKSFPEYKYRKTEEEHQRWR 175 Query: 188 QPLTQQQIDEVPPVEHPVVITHPESGRKILFVSEGFTSHIIGIPRDESDALLKELHAHIT 247 + + + PP+ HPVV THP SG++ LFV+EGFT+ I+ + ES+ALL L AHIT Sbjct: 176 EAVAKN-----PPLLHPVVRTHPVSGKQALFVNEGFTTRIVDVSEKESEALLSFLFAHIT 230 Query: 248 RPENVYTHHWQAHDMVFWDNRSTQHYAAITPQHLRRTLYRTTVEGDVP 295 +PE WQ +D+ WDNR TQHYA RR ++R T+ GD P Sbjct: 231 KPEFQVRWRWQPNDIAIWDNRVTQHYANADYLPQRRIMHRATILGDKP 278 >ZtauD [Q] COG2175 Probable taurine catabolism dioxygenase EcZ Escherichia coli O157:H7 EDL933 Length = 283 Score = 187 bits (475), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 109/288 (37%), Positives = 162/288 (56%), Gaps = 18/288 (6%) Query: 14 QHFEIRPFDAPLGAEIVGLDLNLPVSAQQLARIRGALVEHGVVVFREQRITPQQHIDFSR 73 + I P +GA+I G DL P+S Q ++ A++ H VV R+Q ITPQQ ++ Sbjct: 3 ERLSITPLGPYIGAQISGADLTRPLSDNQFEQLYHAVLRHQVVFLRDQAITPQQQRALAQ 62 Query: 74 RFGPLQVHVLNRFHLAGHPEILIVSNVVENGKPIGLVDAGADWHSDLSYMPKPSLGALLH 133 RFG L +H + H G EI+++ N P +WH+D++++ P GA+L Sbjct: 63 RFGELHIHPVYP-HAEGVDEIIVLD--THNDNP----PDNDNWHTDVTFIETPPAGAILA 115 Query: 134 SQELPAERGDTLYANTAAAWDSLPAALKTQLEGKRAVHSY-----VYRYERLRKL-SPWR 187 ++ELP+ GDTL+ + AA+++L + L G RA H + Y+Y + + WR Sbjct: 116 AKELPSTGGDTLWTSGIAAYEALSVPFRQLLSGLRAEHDFRKSFPEYKYRKTEEEHQRWR 175 Query: 188 QPLTQQQIDEVPPVEHPVVITHPESGRKILFVSEGFTSHIIGIPRDESDALLKELHAHIT 247 + + + PP+ HPVV THP SG++ LFV+EGFT+ I+ + ES+ALL L AHIT Sbjct: 176 EAVAKN-----PPLLHPVVRTHPVSGKQALFVNEGFTTRIVDVSEKESEALLGFLFAHIT 230 Query: 248 RPENVYTHHWQAHDMVFWDNRSTQHYAAITPQHLRRTLYRTTVEGDVP 295 +PE WQ +D+ WDNR TQHYA RR ++R T+ GD P Sbjct: 231 KPEFQVRWRWQPNDIAIWDNRVTQHYANADYLPQRRIMHRATILGDKP 278