BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0033.0008.p (304 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc3266 [R] COG0313 Predicted methyltransferases Rso Ralstonia s... 289 4e-78 YPO3547 [R] COG0313 Predicted methyltransferases Ype Yersinia pe... 275 1e-73 VC0582 [R] COG0313 Predicted methyltransferases Vch Vibrio cholerae 269 5e-72 yraL [R] COG0313 Predicted methyltransferases Eco Escherichia co... 259 6e-69 ZyraL [R] COG0313 Predicted methyltransferases EcZ Escherichia c... 259 6e-69 >RSc3266 [R] COG0313 Predicted methyltransferases Rso Ralstonia solanacearum Length = 300 Score = 289 bits (740), Expect = 4e-78, Method: Compositional matrix adjust. Identities = 164/292 (56%), Positives = 205/292 (70%), Gaps = 7/292 (2%) Query: 15 AAQQSYPVSALYVLATPIGNVCDITLRGLHVLAIADAVACEDTRNTSQLLQRYGLSKQLL 74 A Q YP ALYV+ATPIGN D++LR HVL +ADAVACEDTRNT QLL R GLS+ LL Sbjct: 10 AHDQHYPAGALYVVATPIGNAADVSLRARHVLGLADAVACEDTRNTGQLLHRLGLSRPLL 69 Query: 75 ATHEHNEREAAAKIIERLQAGQRVALVSDAGTPAISDPGARVVDAVRAAGFQVIALPGAS 134 A HEHNEREAAA+I+ERL G+R+A VSDAGTP +SDPGAR+V+AVRAAG +VI LPGAS Sbjct: 70 AAHEHNEREAAARIVERLARGERIAYVSDAGTPGVSDPGARIVEAVRAAGQRVIPLPGAS 129 Query: 135 AAVTALSASG----LTDARFHFVGFLPAKTRQRETALQELVTLQAALVFYEAPHRIVETV 190 A VTALSA+G + +F FVGFLP K QR+TA+++ A V YEAPHRI + Sbjct: 130 AVVTALSAAGALLETSAGQFTFVGFLPPKAGQRDTAIRQWAAHGPAWVLYEAPHRI-DAT 188 Query: 191 QSMLQVFGPTRQVVLARELTKLFEHIHRCPLGEAVAWLEQDANRQRGEFVVLLEGAQPVE 250 + L P R++++ RELTKLFE I P EA AWL DA+ +GEFV+++EGA E Sbjct: 189 LAALAAHLPARRLLIGRELTKLFEQIVVLPAAEAPAWLAADASHGKGEFVLVVEGAGAQE 248 Query: 251 GEDA--EGERVLRILLEELPVKQAAALAAQITGQKKNALYERALQIRQGAQE 300 ++VLR+LL ELP K+AA LA ITG +ALY+ AL ++ ++ Sbjct: 249 AAPTALAADQVLRLLLAELPAKRAAKLAGAITGAPVDALYQSALALKNDGRD 300 >YPO3547 [R] COG0313 Predicted methyltransferases Ype Yersinia pestis Length = 299 Score = 275 bits (702), Expect = 1e-73, Method: Compositional matrix adjust. Identities = 148/284 (52%), Positives = 205/284 (72%), Gaps = 4/284 (1%) Query: 23 SALYVLATPIGNVCDITLRGLHVLAIADAVACEDTRNTSQLLQRYGLSKQLLATHEHNER 82 S LYV+ TPIGN+ DIT R L VL D +A EDTR+T LLQ + ++ +L A H+HNE+ Sbjct: 12 STLYVVPTPIGNLGDITHRALEVLKGVDLIAAEDTRHTGLLLQHFAINARLFALHDHNEQ 71 Query: 83 EAAAKIIERLQAGQRVALVSDAGTPAISDPGARVVDAVRAAGFQVIALPGASAAVTALSA 142 + A +++ +LQ GQ +ALVSDAGTP I+DPG +V R AG +V+ LPGA AA+TALSA Sbjct: 72 QKADQLLAKLQEGQSIALVSDAGTPLINDPGYHLVRRCREAGIRVVPLPGACAAITALSA 131 Query: 143 SGLTDARFHFVGFLPAKTRQRETALQELVTLQAALVFYEAPHRIVETVQSMLQVFGPTRQ 202 +GL RF + GFLPAKT+ R+ LQ L+ L+FYE+ HR++E++Q M+ V GP R Sbjct: 132 AGLASDRFCYEGFLPAKTKGRKDTLQALIEEPRTLIFYESTHRLLESLQDMVTVLGPQRY 191 Query: 203 VVLARELTKLFEHIHRCPLGEAVAWLEQDANRQRGEFVVLLEGAQPVEGED---AEGERV 259 VVLARELTK +E IH P+GE +AW++++ R+RGE V+++EG + V+ +D A+ R Sbjct: 192 VVLARELTKTWESIHGAPVGELLAWVKEEETRRRGEMVLIVEGHK-VQSDDALPADALRT 250 Query: 260 LRILLEELPVKQAAALAAQITGQKKNALYERALQIRQGAQEDED 303 L +L +ELP+K+AAALAA+I G KKNALY+ AL+ +QG E E+ Sbjct: 251 LALLQKELPLKKAAALAAEIHGVKKNALYKYALEQQQGDVETEE 294 >VC0582 [R] COG0313 Predicted methyltransferases Vch Vibrio cholerae Length = 288 Score = 269 bits (688), Expect = 5e-72, Method: Compositional matrix adjust. Identities = 137/272 (50%), Positives = 183/272 (67%), Gaps = 4/272 (1%) Query: 25 LYVLATPIGNVCDITLRGLHVLAIADAVACEDTRNTSQLLQRYGLSKQLLATHEHNEREA 84 LY++ TPIGN+ DIT R L VLA D +A EDTR+T +LL + +S + A H+HNE++ Sbjct: 14 LYIVPTPIGNLGDITQRALDVLASVDMIAVEDTRHTGKLLAHFNISTKTFALHDHNEQQK 73 Query: 85 AAKIIERLQAGQRVALVSDAGTPAISDPGARVVDAVRAAGFQVIALPGASAAVTALSASG 144 A ++++L +G +ALVSDAGTP ISDPG +V R AG +V+ LPG A +TALSASG Sbjct: 74 AQVLVDKLLSGLSIALVSDAGTPLISDPGYHLVTQCRQAGVKVVPLPGPCAVITALSASG 133 Query: 145 LTDARFHFVGFLPAKTRQRETALQELVTLQAALVFYEAPHRIVETVQSMLQVFGPTRQVV 204 L F F GFLPAK++ R+ L E+ + +FYE+PHRI E++Q ML V G R+VV Sbjct: 134 LPSDSFSFEGFLPAKSKARKDKLLEIAKVSRTCIFYESPHRICESLQDMLDVLGGEREVV 193 Query: 205 LARELTKLFEHIHRCPLGEAVAWLEQDANRQRGEFVVLLEGAQPVEGED---AEGERVLR 261 LARELTK FE I PL E + W+ +D NR++GE V+L+ G + GE E R L Sbjct: 194 LARELTKTFETIQGMPLAELITWIAEDDNRKKGEMVLLVHGYRDA-GEQQLPDEALRTLT 252 Query: 262 ILLEELPVKQAAALAAQITGQKKNALYERALQ 293 IL +ELP+K+AAAL A+I KKNALY+ L+ Sbjct: 253 ILTKELPLKKAAALVAEIHQLKKNALYKWGLE 284 >yraL [R] COG0313 Predicted methyltransferases Eco Escherichia coli K12 Length = 286 Score = 259 bits (662), Expect = 6e-69, Method: Compositional matrix adjust. Identities = 138/271 (50%), Positives = 195/271 (71%), Gaps = 3/271 (1%) Query: 25 LYVLATPIGNVCDITLRGLHVLAIADAVACEDTRNTSQLLQRYGLSKQLLATHEHNEREA 84 LY++ TPIGN+ DIT R L VL D +A EDTR+T LLQ +G++ +L A H+HNE++ Sbjct: 14 LYIVPTPIGNLADITQRALEVLQAVDLIAAEDTRHTGLLLQHFGINARLFALHDHNEQQK 73 Query: 85 AAKIIERLQAGQRVALVSDAGTPAISDPGARVVDAVRAAGFQVIALPGASAAVTALSASG 144 A ++ +LQ GQ +ALVSDAGTP I+DPG +V R AG +V+ LPG AA+TALSA+G Sbjct: 74 AETLLAKLQEGQNIALVSDAGTPLINDPGYHLVRTCREAGIRVVPLPGPCAAITALSAAG 133 Query: 145 LTDARFHFVGFLPAKTRQRETALQELVTLQAALVFYEAPHRIVETVQSMLQVFGPTRQVV 204 L RF + GFLPAK++ R AL+ + L+FYE+ HR++++++ ++ V G +R VV Sbjct: 134 LPSDRFCYEGFLPAKSKGRRDALKAIEAEPRTLIFYESTHRLLDSLEDIVAVLGESRYVV 193 Query: 205 LARELTKLFEHIHRCPLGEAVAWLEQDANRQRGEFVVLLEGAQPVEGED--AEGERVLRI 262 LARELTK +E IH P+GE +AW+++D NR++GE V+++EG + E ED A+ R L + Sbjct: 194 LARELTKTWETIHGAPVGELLAWVKEDENRRKGEMVLIVEGHKAQE-EDLPADALRTLAL 252 Query: 263 LLEELPVKQAAALAAQITGQKKNALYERALQ 293 L ELP+K+AAALAA+I G KKNALY+ AL+ Sbjct: 253 LQAELPLKKAAALAAEIHGVKKNALYKYALE 283 >ZyraL [R] COG0313 Predicted methyltransferases EcZ Escherichia coli O157:H7 EDL933 Length = 286 Score = 259 bits (662), Expect = 6e-69, Method: Compositional matrix adjust. Identities = 138/271 (50%), Positives = 195/271 (71%), Gaps = 3/271 (1%) Query: 25 LYVLATPIGNVCDITLRGLHVLAIADAVACEDTRNTSQLLQRYGLSKQLLATHEHNEREA 84 LY++ TPIGN+ DIT R L VL D +A EDTR+T LLQ +G++ +L A H+HNE++ Sbjct: 14 LYIVPTPIGNLADITQRALEVLQAVDLIAAEDTRHTGLLLQHFGINARLFALHDHNEQQK 73 Query: 85 AAKIIERLQAGQRVALVSDAGTPAISDPGARVVDAVRAAGFQVIALPGASAAVTALSASG 144 A ++ +LQ GQ +ALVSDAGTP I+DPG +V R AG +V+ LPG AA+TALSA+G Sbjct: 74 AETLLAKLQEGQNIALVSDAGTPLINDPGYHLVRTCREAGIRVVPLPGPCAAITALSAAG 133 Query: 145 LTDARFHFVGFLPAKTRQRETALQELVTLQAALVFYEAPHRIVETVQSMLQVFGPTRQVV 204 L RF + GFLPAK++ R AL+ + L+FYE+ HR++++++ ++ V G +R VV Sbjct: 134 LPSDRFCYEGFLPAKSKGRRDALKAIEAEPRTLIFYESTHRLLDSLEDIVAVLGESRYVV 193 Query: 205 LARELTKLFEHIHRCPLGEAVAWLEQDANRQRGEFVVLLEGAQPVEGED--AEGERVLRI 262 LARELTK +E IH P+GE +AW+++D NR++GE V+++EG + E ED A+ R L + Sbjct: 194 LARELTKTWETIHGAPVGELLAWVKEDENRRKGEMVLIVEGHKAQE-EDLPADALRTLAL 252 Query: 263 LLEELPVKQAAALAAQITGQKKNALYERALQ 293 L ELP+K+AAALAA+I G KKNALY+ AL+ Sbjct: 253 LQAELPLKKAAALAAEIHGVKKNALYKYALE 283