BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0033.0004.p (198 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value NMB2090 [G] COG0279 Phosphoheptose isomerase Nme Neisseria menin... 242 5e-64 NMA0340 [G] COG0279 Phosphoheptose isomerase NmA Neisseria menin... 242 5e-64 PA4425 [G] COG0279 Phosphoheptose isomerase Pae Pseudomonas aeru... 232 5e-61 VC0579 [G] COG0279 Phosphoheptose isomerase Vch Vibrio cholerae 214 1e-55 yraO [G] COG0279 Phosphoheptose isomerase Eco Escherichia coli K12 198 8e-51 >NMB2090 [G] COG0279 Phosphoheptose isomerase Nme Neisseria meningitidis MC58 Length = 197 Score = 242 bits (617), Expect = 5e-64, Method: Compositional matrix adjust. Identities = 115/188 (61%), Positives = 141/188 (75%) Query: 5 RILAHFQESADLKMKAASVLAQPIEQAIELMFTALSNGNKILACGNGGSAADSQHFAAEL 64 R+ AHF ES K +A VL +P QA ELM L N KILACGNGGSAAD+QHFAAE+ Sbjct: 7 RVAAHFAESIRAKQEAGKVLVEPTVQAAELMLQCLMNDGKILACGNGGSAADAQHFAAEM 66 Query: 65 VGRFERERLPLPALALTTDTSILTAVGNDYSYQEIFSKQVQAFGQAGDILLAFSTSGNSG 124 GRFE+ER+ L A+ALTTDTS LTA+GNDY + +FSKQV+A G+AGD+L+ STSGNS Sbjct: 67 TGRFEKERMELAAVALTTDTSALTAIGNDYGFDHVFSKQVRALGRAGDVLVGISTSGNSA 126 Query: 125 NILAAIEVAHERDMRVVALTGKGGGKIGKILTDADVHICVPHERTARIQEVHLVSLHCIC 184 N++ A++ AHERDM V+ALTG+ GGKI IL D DV + VPH RTARIQE H++ +H +C Sbjct: 127 NVIEAVKAAHERDMHVIALTGRDGGKIAAILKDTDVLLNVPHPRTARIQENHILLIHAMC 186 Query: 185 DGIDVALF 192 D ID L Sbjct: 187 DCIDSVLL 194 >NMA0340 [G] COG0279 Phosphoheptose isomerase NmA Neisseria meningitidis Z2491 Length = 197 Score = 242 bits (617), Expect = 5e-64, Method: Compositional matrix adjust. Identities = 115/188 (61%), Positives = 141/188 (75%) Query: 5 RILAHFQESADLKMKAASVLAQPIEQAIELMFTALSNGNKILACGNGGSAADSQHFAAEL 64 R+ AHF ES K +A VL +P QA ELM L N KILACGNGGSAAD+QHFAAE+ Sbjct: 7 RVAAHFAESIRAKQEAGKVLVEPTVQAAELMLQCLMNDGKILACGNGGSAADAQHFAAEM 66 Query: 65 VGRFERERLPLPALALTTDTSILTAVGNDYSYQEIFSKQVQAFGQAGDILLAFSTSGNSG 124 GRFE+ER+ L A+ALTTDTS LTA+GNDY + +FSKQV+A G+AGD+L+ STSGNS Sbjct: 67 TGRFEKERMELAAVALTTDTSALTAIGNDYGFDHVFSKQVRALGRAGDVLVGISTSGNSA 126 Query: 125 NILAAIEVAHERDMRVVALTGKGGGKIGKILTDADVHICVPHERTARIQEVHLVSLHCIC 184 N++ A++ AHERDM V+ALTG+ GGKI IL D DV + VPH RTARIQE H++ +H +C Sbjct: 127 NVIEAVKAAHERDMHVIALTGRDGGKIAAILKDTDVLLNVPHPRTARIQENHILLIHAMC 186 Query: 185 DGIDVALF 192 D ID L Sbjct: 187 DCIDSVLL 194 >PA4425 [G] COG0279 Phosphoheptose isomerase Pae Pseudomonas aeruginosa Length = 197 Score = 232 bits (591), Expect = 5e-61, Method: Compositional matrix adjust. Identities = 112/191 (58%), Positives = 143/191 (74%) Query: 5 RILAHFQESADLKMKAASVLAQPIEQAIELMFTALSNGNKILACGNGGSAADSQHFAAEL 64 RI FQ S + K +A VL IEQA +M AL N KIL+CGNGGSA D+QHF++EL Sbjct: 6 RIRQLFQASIETKQQALEVLPPYIEQASLVMVNALLNEGKILSCGNGGSAGDAQHFSSEL 65 Query: 65 VGRFERERLPLPALALTTDTSILTAVGNDYSYQEIFSKQVQAFGQAGDILLAFSTSGNSG 124 + RFERER LPA+ALTTD+S +T++ NDYSY E+FSKQ++A GQ GD+LLA STSGNS Sbjct: 66 LNRFERERPSLPAVALTTDSSTITSIANDYSYNEVFSKQIRALGQPGDVLLAISTSGNSA 125 Query: 125 NILAAIEVAHERDMRVVALTGKGGGKIGKILTDADVHICVPHERTARIQEVHLVSLHCIC 184 N++ AI+ AH+R+M VVALTG+ GG + +L DV I VP + TARIQEVHL+++HC+C Sbjct: 126 NVIQAIQAAHDREMLVVALTGRDGGGMASLLLPEDVEIRVPSKITARIQEVHLLAIHCLC 185 Query: 185 DGIDVALFGDD 195 D ID LFG + Sbjct: 186 DLIDRQLFGSE 196 >VC0579 [G] COG0279 Phosphoheptose isomerase Vch Vibrio cholerae Length = 196 Score = 214 bits (545), Expect = 1e-55, Method: Compositional matrix adjust. Identities = 105/183 (57%), Positives = 131/183 (71%) Query: 10 FQESADLKMKAASVLAQPIEQAIELMFTALSNGNKILACGNGGSAADSQHFAAELVGRFE 69 F ES +++ AA L I A + M +L NG+KIL CGNGGS+ ++Q F + L+ RFE Sbjct: 9 FTESIQIQIAAAEALPDAIMHAAQAMVASLLNGHKILCCGNGGSSVNAQQFVSCLLNRFE 68 Query: 70 RERLPLPALALTTDTSILTAVGNDYSYQEIFSKQVQAFGQAGDILLAFSTSGNSGNILAA 129 ER LP +ALT D + LTAV NDY YQEIFSKQV+AFGQ GDILLA STSGNS NI+ A Sbjct: 69 TERPSLPGMALTADNTTLTAVANDYHYQEIFSKQVRAFGQPGDILLAISTSGNSKNIIKA 128 Query: 130 IEVAHERDMRVVALTGKGGGKIGKILTDADVHICVPHERTARIQEVHLVSLHCICDGIDV 189 +E A RDM ++ALTGK GG++ +L + DV I +P RTARI EVH+V+LHC+CD ID Sbjct: 129 MEAAVTRDMTIIALTGKDGGEMAGLLGENDVEIRIPSHRTARIHEVHMVTLHCLCDLIDQ 188 Query: 190 ALF 192 LF Sbjct: 189 VLF 191 >yraO [G] COG0279 Phosphoheptose isomerase Eco Escherichia coli K12 Length = 196 Score = 198 bits (503), Expect = 8e-51, Method: Compositional matrix adjust. Identities = 97/188 (51%), Positives = 131/188 (69%) Query: 5 RILAHFQESADLKMKAASVLAQPIEQAIELMFTALSNGNKILACGNGGSAADSQHFAAEL 64 RI A F ES ++ AA L I +A + +L NGNKIL CGNG SAA++QHFAA + Sbjct: 4 RIKACFTESIQTQIAAAEALPDAISRAAMTLVQSLLNGNKILCCGNGTSAANAQHFAASM 63 Query: 65 VGRFERERLPLPALALTTDTSILTAVGNDYSYQEIFSKQVQAFGQAGDILLAFSTSGNSG 124 + RFE ER LPA+AL TD +LTA+ ND + E+++KQV+A G AGD+LLA ST GNS Sbjct: 64 INRFETERPSLPAIALNTDNVVLTAIANDRLHDEVYAKQVRALGHAGDVLLAISTRGNSR 123 Query: 125 NILAAIEVAHERDMRVVALTGKGGGKIGKILTDADVHICVPHERTARIQEVHLVSLHCIC 184 +I+ A+E A RDM +VALTG GG++ +L DV I +P R+ARIQE+H+++++C+C Sbjct: 124 DIVKAVEAAVTRDMTIVALTGYDGGELAGLLGPQDVEIRIPSHRSARIQEMHMLTVNCLC 183 Query: 185 DGIDVALF 192 D ID LF Sbjct: 184 DLIDNTLF 191