BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0032.0116.p (299 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value AGpA485 [GER] COG0697 Permeases of the drug/metabolite transport... 259 7e-69 YPO2761 [GER] COG0697 Permeases of the drug/metabolite transport... 256 3e-68 PA4287 [GER] COG0697 Permeases of the drug/metabolite transporte... 251 2e-66 RSp1638 [GER] COG0697 Permeases of the drug/metabolite transport... 250 4e-66 AGc4446 [GER] COG0697 Permeases of the drug/metabolite transport... 136 7e-32 >AGpA485 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 309 Score = 259 bits (661), Expect = 7e-69, Method: Compositional matrix adjust. Identities = 144/297 (48%), Positives = 205/297 (69%), Gaps = 2/297 (0%) Query: 3 PMTYKSLWFPLGAVLIWAGNTVISKMSAGVIAPEDISFYRWVLAALLMSPFLARPTWAAR 62 PM K L F L AVLIW GNT++SK++AG IAP I+F RW +A ++++P + R W R Sbjct: 6 PMPVKYLLFSLLAVLIWVGNTIVSKLAAGAIAPGTIAFERWFIAFVILTPLVYRDAWRHR 65 Query: 63 AQIRPYLGKILVLALLGMVLFQSLAYFAAATASATSMGIIASLMPLLTLVLSIKLLSEPP 122 I +L K+++L LLGM Q L Y+AA +AT+M I+ SL+PLLTL+LS L+E P Sbjct: 66 RTIAAHLPKLILLGLLGMAACQGLGYYAAGLTTATNMAIMLSLVPLLTLILSAVFLAERP 125 Query: 123 TVGTLAGGILSLFGLAVLIGRGHPLALFDQGVVTGDLLMLLATIAYGLYGVMLRRWALPL 182 + + GGI+SL G+ +++G+G P L QGV GD +ML A +AY YG++LRRWA+PL Sbjct: 126 SSLAVIGGIISLSGIFIVLGQGDPSRLLSQGVGRGDAMMLAAVLAYAGYGILLRRWAIPL 185 Query: 183 RTWQLLYMQVLMAVVLLFPGYVLGHHSPLTRENLPILLYAGIAASILSQFLWMRGVQYLG 242 TW +Y+Q+ AVVLL P Y+L S LT N ++LYA I SIL+ F+WM V++LG Sbjct: 186 ATWTSIYVQIGAAVVLLVPSYLLSAPSALTLPNTAMVLYAAIPGSILAPFVWMTAVKHLG 245 Query: 243 ASRCAIFVNLMPVFTVIIAVVALGEQLHGYHAIGGLITLAGVIMAQVFKQRLRWRTG 299 A+R AIF+NL+P+FT I+A + LGE L+ YH +GG +T+AG+I+ Q ++ R ++G Sbjct: 246 AARTAIFMNLIPIFTAIVAAIFLGEALYIYHLLGGGMTVAGIILVQ--RKPFREKSG 300 >YPO2761 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Ype Yersinia pestis Length = 305 Score = 256 bits (655), Expect = 3e-68, Method: Compositional matrix adjust. Identities = 154/285 (54%), Positives = 204/285 (71%) Query: 11 FPLGAVLIWAGNTVISKMSAGVIAPEDISFYRWVLAALLMSPFLARPTWAARAQIRPYLG 70 FPL AV+IW+ N V+SK+SA I P ISFYRW+LA L +SPFL IR Y Sbjct: 5 FPLFAVIIWSVNAVVSKISATAIDPAAISFYRWLLALLTLSPFLLLGVVRNWQAIRVYWW 64 Query: 71 KILVLALLGMVLFQSLAYFAAATASATSMGIIASLMPLLTLVLSIKLLSEPPTVGTLAGG 130 K+++L +LGMVL+QSLAY+AA + SA MGI++SL+PLLT+++SI LL PTVG G Sbjct: 65 KLMLLGMLGMVLYQSLAYYAAHSVSALFMGILSSLIPLLTVLISIVLLRVAPTVGIALGS 124 Query: 131 ILSLFGLAVLIGRGHPLALFDQGVVTGDLLMLLATIAYGLYGVMLRRWALPLRTWQLLYM 190 +LSL GL LI G+P+ L G+ G+L+ML A+ +Y LYGV+ +RWA+ L WQ LYM Sbjct: 125 LLSLGGLVWLISAGNPVQLLQHGIGKGELMMLGASASYALYGVLTKRWAIQLPNWQSLYM 184 Query: 191 QVLMAVVLLFPGYVLGHHSPLTRENLPILLYAGIAASILSQFLWMRGVQYLGASRCAIFV 250 Q++ VVLL PG+++ LT +N+P++L+AGI ASIL+ +LW++GV LGA+ +IF+ Sbjct: 185 QIVFGVVLLLPGFLMTPDVQLTAQNIPLVLFAGIPASILAPYLWIQGVMRLGANTASIFM 244 Query: 251 NLMPVFTVIIAVVALGEQLHGYHAIGGLITLAGVIMAQVFKQRLR 295 NL PVFT IIAVV L EQLH YH IGG ITLAGV++AQ + LR Sbjct: 245 NLTPVFTAIIAVVFLHEQLHSYHLIGGGITLAGVVLAQRLRSPLR 289 >PA4287 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Pae Pseudomonas aeruginosa Length = 296 Score = 251 bits (640), Expect = 2e-66, Method: Compositional matrix adjust. Identities = 137/283 (48%), Positives = 199/283 (70%) Query: 11 FPLGAVLIWAGNTVISKMSAGVIAPEDISFYRWVLAALLMSPFLARPTWAARAQIRPYLG 70 FPL AV IWAGNTV++K++ G+I P +I F+RW+L L ++PF+ P R I LG Sbjct: 5 FPLLAVFIWAGNTVVNKLAVGIIQPAEIGFFRWLLVGLALTPFMLGPVLRNRRYILANLG 64 Query: 71 KILVLALLGMVLFQSLAYFAAATASATSMGIIASLMPLLTLVLSIKLLSEPPTVGTLAGG 130 K +VL LLGM ++QSLAY+AAA SAT+MGII SLMPL++L L+ +L+ G L G Sbjct: 65 KFVVLGLLGMAVYQSLAYYAAALTSATNMGIILSLMPLMSLGLASSILAHRLNAGALLGA 124 Query: 131 ILSLFGLAVLIGRGHPLALFDQGVVTGDLLMLLATIAYGLYGVMLRRWALPLRTWQLLYM 190 ++SL G+ ++I +GH AL + GV GD +M++AT+AY +Y V+L++W+L L QLLY+ Sbjct: 125 LVSLAGVVLVISQGHLGALLEHGVNLGDAMMIVATLAYAVYSVLLKKWSLKLPAMQLLYL 184 Query: 191 QVLMAVVLLFPGYVLGHHSPLTRENLPILLYAGIAASILSQFLWMRGVQYLGASRCAIFV 250 QVL+A++ L P Y+L + L NLP++LYA + ASI++ WM GV LG SR A+F Sbjct: 185 QVLVAILALLPLYLLSPRTGLNAANLPLVLYAALFASIVAALAWMHGVARLGPSRMALFF 244 Query: 251 NLMPVFTVIIAVVALGEQLHGYHAIGGLITLAGVIMAQVFKQR 293 NL+P+ T IA + LGE+L +H +GG +TLAGV++A+ +++R Sbjct: 245 NLLPIITACIATLVLGERLTVHHLVGGALTLAGVLLAEFWQRR 287 >RSp1638 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Rso Ralstonia solanacearum Length = 297 Score = 250 bits (638), Expect = 4e-66, Method: Compositional matrix adjust. Identities = 130/291 (44%), Positives = 197/291 (67%), Gaps = 6/291 (2%) Query: 11 FPLGAVLIWAGNTVISKMSAGVIAPEDISFYRWVLAALLMSPFLARPTWAARAQIRPYLG 70 +PL AVL+WA NT++SK +AGV+ P IS YRWV+AA +++PF ARP W R + P+L Sbjct: 5 YPLLAVLVWAANTIVSKAAAGVLDPAAISLYRWVIAAAVLTPFWARPLWRQRRDVLPWLP 64 Query: 71 KILVLALLGMVLFQSLAYFAAATASATSMGIIASLMPLLTLVLSIKLLSEPPTVGTLAGG 130 ++ VLALLG+V++Q L+Y+AA + SAT++G+I +L+P+L L+++ + +P +AG Sbjct: 65 RLSVLALLGLVMYQCLSYYAAYSTSATNIGVICALIPMLGLIINGVVFRQPVGAPAVAGI 124 Query: 131 ILSLFGLAVLIGRGHPLALFDQGVVTGDLLMLLATIAYGLYGVMLRRWALPLRTWQLLYM 190 +SL G+ L+GRGHP +LFD GV GD+L+L+ + AY LY ++ RRWA P W LY+ Sbjct: 125 AVSLLGVLYLLGRGHPASLFDGGVNRGDVLVLIGSAAYALYNILYRRWAPPFGQWLNLYL 184 Query: 191 QVLMAVVLLFPGYVLGHHSPLTRENLPILLYAGIAASILSQFLWMRGVQYLGASRCAIFV 250 Q L+AVV+L P + ++ + ++L+AGI ASI++ + WM G+ LG+ R + + Sbjct: 185 QALLAVVMLLPLAFTARSLAIPQQGIGMVLFAGIGASIVAMYWWMLGLARLGSERTVVMM 244 Query: 251 NLMPVFTVIIAVVALGEQLHGYHAIGGLITLAGVIMAQ------VFKQRLR 295 NL+PVFT ++A LGE +HGYH IGG + L GV + Q + + RLR Sbjct: 245 NLLPVFTALMASAMLGETIHGYHWIGGGLILLGVSLVQGIVTLPMGRDRLR 295 >AGc4446 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 302 Score = 136 bits (342), Expect = 7e-32, Method: Compositional matrix adjust. Identities = 97/289 (33%), Positives = 155/289 (53%), Gaps = 19/289 (6%) Query: 15 AVLIWAGNTVISKMSAGVIAPEDISFYRWVLAALLM----SPFLARPTWAARAQIRPYLG 70 A L W GNTV K++ G I+P +F RWVLA ++ P L + W Q PY Sbjct: 19 ATLCWGGNTVAGKLAVGHISPMAFTFLRWVLAVAIIFAISVPQLIK-DWPVVKQRLPYF- 76 Query: 71 KILVLALLGMVLFQSLAYFAAATASATSMGIIASLMPLLTLVLSIKLLSEPPTVGTLAGG 130 VL +G F Y A SA + +I + +P++ VL+ L G +AG Sbjct: 77 --FVLGSVGYTAFNVFLYTALQHTSAINAAVIQAGIPMVIFVLNFVLFRTRVLFGQIAGF 134 Query: 131 ILSLFGLAVLIGRGHPLALFDQGVVTGDLLMLLATIAYGLYGVMLRRWALPLRTWQLL-- 188 L++ G+A+L G PL+L + GD +MLLA + Y +Y V+LR W P W+ L Sbjct: 135 CLTISGVALLASHGDPLSLLQLEMNVGDAVMLLAVLVYAIYTVILR-WK-PAVDWRTLMA 192 Query: 189 ---YMQVLMAVVLLFPGYVLGHHSPL--TRENLPILLYAGIAASILSQFLWMRGVQYLGA 243 + +L +V L+F + + S + ++ +++YAGI AS+++Q L+++GV+ +GA Sbjct: 193 IPAFFALLTSVPLVF--FEMSRESLIWPDQKGWMLVVYAGIFASLIAQILYIKGVEQIGA 250 Query: 244 SRCAIFVNLMPVFTVIIAVVALGEQLHGYHAIGGLITLAGVIMAQVFKQ 292 +R +F+NL+PVF +++V L E LH Y + LAG+ +A+ K Sbjct: 251 NRAGLFINLVPVFGTLLSVFVLSETLHTYQIAALFMALAGIAVAERKKS 299