BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0032.0115.p (608 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mll8348 [GEPR] COG0477 Permeases of the major facilitator superf... 445 e-124 BMEII0596 [GEPR] COG0477 Permeases of the major facilitator supe... 439 e-122 SMc00813 [GEPR] COG0477 Permeases of the major facilitator super... 421 e-117 AGc1103 [GEPR] COG0477 Permeases of the major facilitator superf... 409 e-113 mll1728 [GEPR] COG0477 Permeases of the major facilitator superf... 327 7e-89 >mll8348 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 473 Score = 445 bits (1145), Expect = e-124, Method: Compositional matrix adjust. Identities = 240/456 (52%), Positives = 317/456 (69%), Gaps = 4/456 (0%) Query: 147 IPLIVACALFMEQMDSTVKPCLXKSSRALALDMKVDPISLKLALTSYLVSLAVFIPISGW 206 IPLI+A ALFME MDSTV + S A+A+D+ PI+LKLALT+YLVSLA+FIPISGW Sbjct: 5 IPLILAVALFMENMDSTV---IATSLPAIAIDIHTSPIALKLALTAYLVSLAIFIPISGW 61 Query: 207 MADRFGSLTIFRTAICVFMLGSILCGASSTLPQFVAARFLQGIGGAMMVPVGRLVILRSV 266 MADRFG+ IFR AI VF++GS+ C S +LP FV +RFLQGIGGAMM PVGRLV++R+ Sbjct: 62 MADRFGAKNIFRAAIAVFIVGSVACALSGSLPAFVVSRFLQGIGGAMMTPVGRLVLVRAT 121 Query: 267 EKVNLVKALSYLTIPALFGPVLGPPLGGFITTYFHWRWIFFINIPISILGLYLATRFIPD 326 K +LV A+S+LT+PAL GP++GPP+GGFITTYF W WIF IN+PI ++G++LATRF+P+ Sbjct: 122 PKSDLVAAMSWLTVPALVGPLVGPPIGGFITTYFTWHWIFLINVPIGLVGIWLATRFLPE 181 Query: 327 LKAEQVSRLDIVGFLLSALGCSLLMMGLATSGRHLVSGDISLACVVAGVLFLCAYVWHAR 386 ++ + LD +GF+LS L S ++ GL+ + V G+L Y+ HAR Sbjct: 182 TESMETPPLDFIGFVLSGLAASGVVFGLSVVSLPYLPPATGFITVGVGLLSGALYLMHAR 241 Query: 387 RATAPLIDLALLKIPTLRAGVFGGSLYRVGIGAIPFLLPLMLQLGFGYTPFHSGLLTCAS 446 RA PL+ L L + R+ V GGSL+R+GIGA+PFLLPLM Q+GFG TPF SG++T S Sbjct: 242 RAKNPLLALELFRNQVFRSSVLGGSLFRIGIGAVPFLLPLMFQIGFGLTPFQSGMITFVS 301 Query: 447 AAGAMFMKTIAARFLRRYGFRRVLLVNGALGVLGLWALATFTPQTPYLVMLIILLVGGCF 506 A GA+ MK + A R GFRRVL++ + + FTP+TPY++ML ILLVGG Sbjct: 302 AVGAIGMKFVTALIFRVAGFRRVLIIGSLVAAASIAIYGLFTPETPYVLMLAILLVGGFI 361 Query: 507 RSLQFTSLNAISYADVDKVRLSQATSMASVAQQLSIGMGVVLAGFALQMSNELQGHATLV 566 RS+ FT +NA+SYA+V S+AT + +V QQLSI +GV LAG L++S + G L+ Sbjct: 362 RSMFFTGVNALSYAEVSAEDTSKATPITAVFQQLSIALGVALAGGILEVSTSIHG-GPLM 420 Query: 567 AQDFWPAFLVVGAVSALALLMLRQLPPNAGAEMAGQ 602 DF AF +V AVSA A L +L P+AG ++G Sbjct: 421 LGDFHIAFFIVAAVSAAASLSFMRLAPDAGNAVSGH 456 >BMEII0596 [GEPR] COG0477 Permeases of the major facilitator superfamily Bme Brucella melitensis Length = 469 Score = 439 bits (1128), Expect = e-122, Method: Compositional matrix adjust. Identities = 236/455 (51%), Positives = 308/455 (67%), Gaps = 4/455 (0%) Query: 146 IIPLIVACALFMEQMDSTVKPCLXKSSRALALDMKVDPISLKLALTSYLVSLAVFIPISG 205 IIPL++A ALFMEQMDS V + S A+A D+ PI+LKLALT+YLV+LAVFIP+SG Sbjct: 4 IIPLVLAIALFMEQMDSNV---ISTSLPAIAADIGTSPIALKLALTAYLVALAVFIPVSG 60 Query: 206 WMADRFGSLTIFRTAICVFMLGSILCGASSTLPQFVAARFLQGIGGAMMVPVGRLVILRS 265 WMADRFG+ +FR AI VF++GSI C AS++LP FV ARFLQG+GGAMM PVGRLV++RS Sbjct: 61 WMADRFGAKNVFRAAIAVFVVGSIACAASNSLPAFVIARFLQGMGGAMMTPVGRLVLIRS 120 Query: 266 VEKVNLVKALSYLTIPALFGPVLGPPLGGFITTYFHWRWIFFINIPISILGLYLATRFIP 325 + LV A+++LTIPA+ GP++GPP+GGFITT+ W WIF IN+PI ++G++ AT F+P Sbjct: 121 TPRNELVSAMAWLTIPAMVGPLVGPPVGGFITTFLTWHWIFLINVPIGMIGIWFATHFLP 180 Query: 326 DLKAEQVSRLDIVGFLLSALGCSLLMMGLATSGRHLVSGDISLACVVAGVLFLCAYVWHA 385 D + + RLD GF LS S ++ GL+ + I A + G+L YV HA Sbjct: 181 DNEERIIKRLDWPGFFLSGFAMSGVVFGLSVVSLPALPPVIGFATLAVGMLCTVLYVLHA 240 Query: 386 RRATAPLIDLALLKIPTLRAGVFGGSLYRVGIGAIPFLLPLMLQLGFGYTPFHSGLLTCA 445 RR PL++L L R+ VFGGS++R GIGAIPFLLPLM QLGFG TPF SG++T Sbjct: 241 RRTPDPLLNLRLFDNQVFRSAVFGGSIFRFGIGAIPFLLPLMFQLGFGLTPFQSGMMTFV 300 Query: 446 SAAGAMFMKTIAARFLRRYGFRRVLLVNGALGVLGLWALATFTPQTPYLVMLIILLVGGC 505 SA GA+ MK A R R FRR L+ + + TFTP TPY +++ LLVGG Sbjct: 301 SAIGAISMKFGAKRIFTRISFRRALMGGSLISAAFIAVNGTFTPATPYWIIIGFLLVGGF 360 Query: 506 FRSLQFTSLNAISYADVDKVRLSQATSMASVAQQLSIGMGVVLAGFALQMSNELQGHATL 565 RSL FT +NA+++A++ + SQAT + +VAQQ+SI +GV LAG L++S L+G A L Sbjct: 361 ARSLFFTGVNALAFAEIPNEKTSQATPLTAVAQQVSIAIGVALAGGILEISTMLRG-APL 419 Query: 566 VAQDFWPAFLVVGAVSALALLMLRQLPPNAGAEMA 600 DF F VV VS LA +L P+AG E+A Sbjct: 420 ALVDFHIGFFVVACVSVLAFFWFARLAPDAGKELA 454 >SMc00813 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 470 Score = 421 bits (1082), Expect = e-117, Method: Compositional matrix adjust. Identities = 220/458 (48%), Positives = 308/458 (67%), Gaps = 4/458 (0%) Query: 146 IIPLIVACALFMEQMDSTVKPCLXKSSRALALDMKVDPISLKLALTSYLVSLAVFIPISG 205 I+PLI+A ALFMEQMDSTV + S A+A DM V PI+LKLALTSY+V+LA+FIP+SG Sbjct: 4 IVPLILAVALFMEQMDSTV---ISTSLPAIARDMGVGPITLKLALTSYMVALAIFIPLSG 60 Query: 206 WMADRFGSLTIFRTAICVFMLGSILCGASSTLPQFVAARFLQGIGGAMMVPVGRLVILRS 265 WMADRFG+ IFR AI VF+ GS+ C + +L FV ARFLQG+GGAMM PV RLV++RS Sbjct: 61 WMADRFGAKRIFRAAILVFIAGSVFCAVADSLFAFVVARFLQGMGGAMMTPVARLVLVRS 120 Query: 266 VEKVNLVKALSYLTIPALFGPVLGPPLGGFITTYFHWRWIFFINIPISILGLYLATRFIP 325 + LV A++ LTIPAL GP+ GPPLGGFITTYF W WIF IN+P+ I+G +L+ ++P Sbjct: 121 APRSELVSAMALLTIPALVGPLAGPPLGGFITTYFSWHWIFLINVPVGIVGYFLSGIYLP 180 Query: 326 DLKAEQVSRLDIVGFLLSALGCSLLMMGLATSGRHLVSGDISLACVVAGVLFLCAYVWHA 385 +++ +DI+GFLL + + ++ GL+ + I +A V AGV Y++HA Sbjct: 181 EMERRNPPPVDIIGFLLGGIAAAGVVFGLSVISLPALPPAIGIASVSAGVAASLLYIFHA 240 Query: 386 RRATAPLIDLALLKIPTLRAGVFGGSLYRVGIGAIPFLLPLMLQLGFGYTPFHSGLLTCA 445 RR AP++DL L + RA GG+++R+ +GA+PFL+PLMLQ+GFG +PF SGL+T Sbjct: 241 RRHPAPVLDLKLFRDGAFRAASIGGTIFRISVGAVPFLMPLMLQVGFGLSPFQSGLITFV 300 Query: 446 SAAGAMFMKTIAARFLRRYGFRRVLLVNGALGVLGLWALATFTPQTPYLVMLIILLVGGC 505 A GA+ K +A R GFR LL+ + + +A FTP TPYL+++ +LL+ G Sbjct: 301 GAVGAITTKFLARRVFAFAGFRTTLLIAAVIAAVTTFANGFFTPATPYLLLISVLLIAGF 360 Query: 506 FRSLQFTSLNAISYADVDKVRLSQATSMASVAQQLSIGMGVVLAGFALQMSNELQGHATL 565 RS FT +NA+S+AD+D S+ATSM++V QQ+S+ +GV +AG L+ L G Sbjct: 361 ARSFFFTGVNALSFADIDDADASKATSMSAVLQQISLALGVAVAGAILEFETALSGKPLE 420 Query: 566 VAQDFWPAFLVVGAVSALALLMLRQLPPNAGAEMAGQQ 603 +A DF AF+++ + LA + + NAGA ++G + Sbjct: 421 LA-DFHVAFMIIAIANLLAAIPFIAMAKNAGASVSGHR 457 >AGc1103 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 475 Score = 409 bits (1051), Expect = e-113, Method: Compositional matrix adjust. Identities = 223/471 (47%), Positives = 318/471 (67%), Gaps = 10/471 (2%) Query: 142 PRTFIIPLIVACALFMEQMDSTVKPCLXKSSRALALDMKVDPISLKLALTSYLVSLAVFI 201 P IIPLI+A ALFMEQMDSTV + S A+A D+ V PI+LKLALT+Y+V+LA+FI Sbjct: 10 PMNRIIPLILAVALFMEQMDSTV---IATSLPAIAKDLHVGPITLKLALTAYMVALAIFI 66 Query: 202 PISGWMADRFGSLTIFRTAICVFMLGSILCGASSTLPQFVAARFLQGIGGAMMVPVGRLV 261 PISGWMAD++G+ IFR AI VF++GSI C SS++ +FV +RFLQG+GGAMM PVGRLV Sbjct: 67 PISGWMADKYGAKKIFRIAIGVFVVGSICCAVSSSVFEFVLSRFLQGMGGAMMTPVGRLV 126 Query: 262 ILRSVEKVNLVKALSYLTIPALFGPVLGPPLGGFITTYFHWRWIFFINIPISILGLYLAT 321 +LR+ ++ LV A++ LTIP L GP+ GPP+GGFITTYF W WIF IN+PI I+G++L+T Sbjct: 127 LLRTTKRSELVSAMALLTIPGLVGPLTGPPIGGFITTYFSWHWIFLINVPIGIIGIWLST 186 Query: 322 RFIPDLKAEQVSRLDIVGFLLSALGCSLLMMGLATSGRHLVSGDISLACVVAGVLFLCAY 381 F+P+++ +D GF+LS + S ++ G++ + I +A V G F+C + Sbjct: 187 IFLPEIETTNPPPMDGKGFILSGIAASGVVFGVSVVSLPALPPAIGIASTVIG--FICGF 244 Query: 382 VW--HARRATAPLIDLALLKIPTLRAGVFGGSLYRVGIGAIPFLLPLMLQLGFGYTPFHS 439 ++ HA R AP++D + + T RA GG+++R+ GAIPFL+PLMLQ+GFG PF S Sbjct: 245 LYMRHAARHPAPILDFRIFQNATFRAASVGGTVFRISTGAIPFLMPLMLQIGFGLNPFQS 304 Query: 440 GLLTCASAAGAMFMKTIAARFLRRYGFRRVLLVNGALGVLGLWALATFTPQTPYLVMLII 499 G++T A A GA+ K +A R GFR L+ G +G A + FTP+TPY +++I Sbjct: 305 GMITFAGAIGAITTKFMAKRVFAATGFRSTLIGAGIVGAFTTLANSFFTPETPYPLIMIF 364 Query: 500 LLVGGCFRSLQFTSLNAISYADVDKVRLSQATSMASVAQQLSIGMGVVLAGFALQMSNEL 559 L+ G RS FT NA+SY+D++ + SQATSMASV QQ+S+ +GV A L++S+ + Sbjct: 365 LVTAGFARSFFFTGSNALSYSDIEDSQASQATSMASVLQQISLALGVAFAASILEVSSMM 424 Query: 560 QGHATLVAQDFWPAFLVVGAVSALALLMLRQLPPNAGAEMAGQ--QENKPA 608 G +A DF AF +V VS A++ + ++ AGA ++G + ++PA Sbjct: 425 SGTHLQLA-DFHIAFTIVALVSLFAIVPIIRMDAQAGAAVSGHRGKVSQPA 474 >mll1728 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 477 Score = 327 bits (837), Expect = 7e-89, Method: Compositional matrix adjust. Identities = 196/473 (41%), Positives = 290/473 (61%), Gaps = 10/473 (2%) Query: 136 PLTMPIPRTFI----IPLIVACALFMEQMDSTVKPCLXKSSRALALDMKVDPISLKLALT 191 P T +P T + LIVA A FM+ +DST+ + S + V +++ + +T Sbjct: 5 PETEALPETATNARRVALIVAIAFFMQLLDSTI---ISTSLPQMGQSYGVPAVAMSVGIT 61 Query: 192 SYLVSLAVFIPISGWMADRFGSLTIFRTAICVFMLGSILCGASSTLPQFVAARFLQGIGG 251 Y++++AVF+P+SGW+ADRFG+ IF AI +F L S+ CG S L QFVAAR +QG+G Sbjct: 62 VYMLTMAVFVPLSGWLADRFGARNIFLVAIALFTLASLACGFSQNLTQFVAARAVQGLGS 121 Query: 252 AMMVPVGRLVILRSVEKVNLVKALSYLTIPALFGPVLGPPLGGFITTYFHWRWIFFINIP 311 A+M PVGR+++LR+ K L+ A + +T PALF PV+GP LGGFITT W W FFINIP Sbjct: 122 ALMTPVGRILVLRNASKSELLNATALITWPALFAPVVGPVLGGFITTTLSWHWNFFINIP 181 Query: 312 ISILGLYLATRFIPDLKAEQVSRLDIVGFLLSALGCSLLMMGLATSGRHLVSGDI-SLAC 370 + ++GL L RFIP + LD GF L++LG + L+ GL H G + ++ Sbjct: 182 LGLIGLALVARFIPGDRVANPKPLDWPGFFLTSLGLACLLYGLERIA-HPEDGMLPTVLL 240 Query: 371 VVAGVLFLCAYVWHARRATAPLIDLALLKIPTLRAGVF-GGSLYRVGIGAIPFLLPLMLQ 429 + AG++ V H RRA PL+DL+ K+ T G+++RV I A PFLLPL+ Q Sbjct: 241 IAAGIVIGWLAVRHLRRAPHPLLDLSSFKVLTFAISTLAAGTIFRVAINATPFLLPLLFQ 300 Query: 430 LGFGYTPFHSGLLTCASAAGAMFMKTIAARFLRRYGFRRVLLVNGALGVLGLWALATFTP 489 LGFG +P +GL+ A G + MKT+ LRR+GFR V++VNG + + A +P Sbjct: 301 LGFGLSPVDAGLMILAYFVGNLGMKTVTTPTLRRFGFRSVMVVNGIIASASIMACGVISP 360 Query: 490 QTPYLVMLIILLVGGCFRSLQFTSLNAISYADVDKVRLSQATSMASVAQQLSIGMGVVLA 549 QTP ++++++L+ G RS+QFT+LN +++AD+D R S A +++S+ QQ+++ GV +A Sbjct: 361 QTPQALVVVLMLIAGLSRSMQFTALNTLAFADIDAARRSSAATLSSMLQQVAMLFGVAVA 420 Query: 550 GFALQMSNELQGHATLVAQDFWPAFLVVGAVSALALLMLRQLPPNAGAEMAGQ 602 L +S + +L DF AF V+GA+ +A L LP AGAE++G Sbjct: 421 AAILNLSQIARAQPSLDLVDFRIAFFVIGAIGLVAALRFLVLPRAAGAEVSGH 473