BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0032.0113.p (1078 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp1199 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia s... 1416 0.0 YPO2849 [V] COG0841 Cation/multidrug efflux pump Ype Yersinia pe... 1260 0.0 ECs2884 [V] COG0841 Cation/multidrug efflux pump Ecs Escherichia... 1233 0.0 yegO [V] COG0841 Cation/multidrug efflux pump Eco Escherichia co... 1230 0.0 ZyegO [V] COG0841 Cation/multidrug efflux pump EcZ Escherichia c... 1227 0.0 >RSp1199 [V] COG0841 Cation/multidrug efflux pump Rso Ralstonia solanacearum Length = 1033 Score = 1416 bits (3665), Expect = 0.0, Method: Compositional matrix adjust. Identities = 709/1057 (67%), Positives = 858/1057 (81%), Gaps = 47/1057 (4%) Query: 1 MNISLPFIKRPIATTLLTIGIALAGMVAFRLLPVSPLPQVDYPTISISASLPGASPETMA 60 MN+S FI RP+AT LLTIG+ALAG+ AF LLPVSPLPQVD+PTIS++ASLPGASPETMA Sbjct: 1 MNLSATFIARPVATALLTIGVALAGIAAFNLLPVSPLPQVDFPTISVNASLPGASPETMA 60 Query: 61 ATVATPLERAMGAIAGVTEMTSTSSQNSTRITLQFDLNRDIDGAARDVQAALNAARNLLP 120 ATVATPLER++G IAG+TEMTS S+ STR+TLQFDL+RDIDGAARDVQAA+NA+R+LLP Sbjct: 61 ATVATPLERSLGRIAGITEMTSQSALGSTRVTLQFDLSRDIDGAARDVQAAINASRSLLP 120 Query: 121 TGMPSNPTYRKVNPADAPILILAMTSDTMTQGQMYDAADSIVAQKLSQVRGVGQVSVGGS 180 +G+PSNPTYRKVNPADAPI+IL +TSDT ++G++YDAA +I+AQKLSQ+ GVGQV++GG+ Sbjct: 121 SGLPSNPTYRKVNPADAPIMILGLTSDTKSRGELYDAASTILAQKLSQITGVGQVNIGGA 180 Query: 181 SQPAVRIELNPTALNKYGIGSADVRTAVAATNANRPKGLLEDDGRNWQIYANDQAKTAAE 240 S PAVR+ELNPTALNKYGI + VRT + ATNAN+PKG+LE R W +YANDQA+ A E Sbjct: 181 SLPAVRVELNPTALNKYGISTETVRTVITATNANKPKGMLEAGNRVWTLYANDQARHAEE 240 Query: 241 YAPLIVSYRNGTPVRVQDVAEVRDSVADVRNAGSSNGKPSVLIIINRQPGANIIETVDNV 300 Y PLI++YRNG PVR+ DVAEV DSV D+RN GS+NGKPSVL+IINRQPGANII+TVD + Sbjct: 241 YKPLIIAYRNGAPVRLSDVAEVTDSVQDIRNYGSANGKPSVLLIINRQPGANIIDTVDRI 300 Query: 301 RALLPQLQASIPSAIDMKVVLDRTPTIRASLKETEFTLMLSVALVIMVVFLFLRNARATL 360 A+LP L+ +IP+ I++ V++DRTPTIRASL++ E TLMLS+ LVIMVV+LFLRN RATL Sbjct: 301 NAILPYLRNTIPAQINLDVMMDRTPTIRASLRDVERTLMLSIGLVIMVVYLFLRNLRATL 360 Query: 361 IPAVAVPVSLIGTFGIMYLAGFSLDNLSLMALTIATGFVVDDAIVVLENISRYIEAGMKP 420 IP+VAVPVSLIGTFG+MYL G+SLDNLSLMALT+ATGFVVDDAIVVLEN+SR+IE GM+P Sbjct: 361 IPSVAVPVSLIGTFGVMYLCGYSLDNLSLMALTVATGFVVDDAIVVLENVSRHIENGMRP 420 Query: 421 YKAALLGAREVGFTVLSMSISLIAVFIPILMMEGIVGRLFREFAITLSVAILVSLVVSLT 480 +AAL GAREVGFTV+SMS SLIAVFIP+LMM GIVGRLFREFA+TLSVAILVSL +SLT Sbjct: 421 MQAALKGAREVGFTVVSMSFSLIAVFIPLLMMGGIVGRLFREFAVTLSVAILVSLAISLT 480 Query: 481 TTPMMCAQLLRHDPEGDAARRERRHPWLQKIADQSAAIFEDMLLAYERTLAWALRAAPLM 540 TTPMMCA+LL+ E + W + ++ F +L Y +LAWALR + L Sbjct: 481 TTPMMCARLLKPASEEEPG-------WFHR---KTEGFFNLLLDGYRHSLAWALRHSWLT 530 Query: 541 MLILLGTIALNVYLYKAIPKGFFPQQDTGRLVGGIRGDQAISFQAMRTKLNEFIDIVKAD 600 +LILL T+ LN YLY +PKGFFPQQD GRL+G I+ DQAISFQAMRTKL +FI IV+ D Sbjct: 531 LLILLATVCLNGYLYVVVPKGFFPQQDVGRLMGFIQADQAISFQAMRTKLVDFIHIVQQD 590 Query: 601 PAVSDVVAFTGGQRRNGGFMYVTLKPLSERKDSADKIVARLRIKTAKVAGARVFLVPVQD 660 PAV +VV FTGG + N G M++ LKPL+ERK SAD+++ RLR K A+ GA +FL VQD Sbjct: 591 PAVENVVGFTGGSQINSGQMFIQLKPLAERKLSADQVINRLRGKLAREPGANLFLQAVQD 650 Query: 661 IRIGARQSDSQYEYSLKSDDVGLLRIWEPKIRLALSNLKELEDISTDQQDNGLQTTLTID 720 IRIG R S++QY+Y+L++D++ LR WEPKIR AL+ +K L D++TD QD G QT L D Sbjct: 651 IRIGGRPSNAQYQYTLQADNLEELRAWEPKIRQALTQIKSLVDVNTDAQDKGQQTALVFD 710 Query: 721 RETAMRAGVTPQLIDSTLSDLFGQRQISTIYSGMNQYHVVMEAAPQYWQSPETLRDTYVS 780 R+ AM G+TP+ ID+ L++ FGQRQ+STIY+ +NQY VVMEAAPQYWQ+PE LRD Y Sbjct: 711 RDKAMALGITPKDIDNALNNAFGQRQVSTIYNPLNQYRVVMEAAPQYWQNPEGLRDIY-- 768 Query: 781 LAGSSNLSPTTSSLSTPPALSAAGKLNANTGLAQTISTAASTQIPLAAFSRFEPTTTALS 840 + TA+ Q+PL+ FS + PT T L+ Sbjct: 769 -----------------------------------LITASGAQVPLSTFSHYGPTNTPLA 793 Query: 841 VSHEGQFVASTLSFNLAEGVSLSQATAAIDRAMAQLGVPTSVLGTFAGTANAFQASTSSQ 900 V+H+GQF ASTLSFNLA G SLS AT I AM ++GVPT+V G+F GTA AFQ S SSQ Sbjct: 794 VNHQGQFAASTLSFNLAPGASLSAATQQIQDAMNRIGVPTTVHGSFQGTARAFQDSLSSQ 853 Query: 901 PILILTALLAVYIVLGILYESLIHPITIISTLPSAGVGALLALMVTGTDFSLIALIGVIL 960 P+LIL AL+ +YIVLG+LYES +HPITI+STLPSAGVGALLAL+VT TDFS+IALIGVIL Sbjct: 854 PVLILFALITIYIVLGVLYESYVHPITILSTLPSAGVGALLALIVTDTDFSVIALIGVIL 913 Query: 961 LIGIVKKNAIMMVDFAIDAERNRGMSPRDAIFEACKLRFRPIMMTTMAALLGAIPLAIGH 1020 LIGIVKKNAIMM+DFA++AER++GMSP DAIF AC LRFRPI+MTTMAALLGA+PLA+GH Sbjct: 914 LIGIVKKNAIMMIDFALEAERSQGMSPADAIFHACVLRFRPILMTTMAALLGALPLALGH 973 Query: 1021 GDGAELRQPLGISIVGGLVVSQLLTLYTTPVVYLYME 1057 GDGAELRQPLGISIVGGL+VSQ+LTLYTTPVVYL ++ Sbjct: 974 GDGAELRQPLGISIVGGLLVSQILTLYTTPVVYLALD 1010 >YPO2849 [V] COG0841 Cation/multidrug efflux pump Ype Yersinia pestis Length = 1024 Score = 1260 bits (3260), Expect = 0.0, Method: Compositional matrix adjust. Identities = 646/1068 (60%), Positives = 809/1068 (75%), Gaps = 60/1068 (5%) Query: 7 FIKRPIATTLLTIGIALAGMVAFRLLPVSPLPQVDYPTISISASLPGASPETMAATVATP 66 FI+RP+ATTLLT+ I L+G++ F LLPVSPLPQVDYP I +SAS+PGA PETMA++VATP Sbjct: 7 FIQRPVATTLLTLAITLSGIIGFSLLPVSPLPQVDYPVIMVSASMPGADPETMASSVATP 66 Query: 67 LERAMGAIAGVTEMTSTSSQNSTRITLQFDLNRDIDGAARDVQAALNAARNLLPTGMPSN 126 LERA+G IAGV EMTSTSS STRI LQFDLNRDI+GAARDVQAALNAA++LLP+GMPS Sbjct: 67 LERALGRIAGVNEMTSTSSLGSTRIILQFDLNRDINGAARDVQAALNAAQSLLPSGMPSR 126 Query: 127 PTYRKVNPADAPILILAMTSDTMTQGQMYDAADSIVAQKLSQVRGVGQVSVGGSSQPAVR 186 PTYRK+NP+DAPI+I+ +TSDT +QGQ+YD A + +AQK++Q GV V+VGGSS PAVR Sbjct: 127 PTYRKMNPSDAPIMIMTLTSDTFSQGQLYDYASTKLAQKIAQTEGVSDVTVGGSSLPAVR 186 Query: 187 IELNPTALNKYGIGSADVRTAVAATNANRPKGLLEDDGRNWQIYANDQAKTAAEYAPLIV 246 +ELNP+AL G+ VR A++A N RP+G ++ +WQ+ AND+ KTA Y PLIV Sbjct: 187 VELNPSALFNQGVSLDAVRQAISAANVRRPQGSVDAAETHWQVQANDEIKTAEGYRPLIV 246 Query: 247 SYRNGTPVRVQDVAEVRDSVADVRNAGSSNGKPSVLIIINRQPGANIIETVDNVRALLPQ 306 Y NG+PVR+QDVA V DSV DVRNAG S G+P+VL++I+R+PGANII TVD +RA LP Sbjct: 247 HYNNGSPVRLQDVANVIDSVQDVRNAGMSAGQPAVLLVISREPGANIIATVDRIRAELPA 306 Query: 307 LQASIPSAIDMKVVLDRTPTIRASLKETEFTLMLSVALVIMVVFLFLRNARATLIPAVAV 366 L+ASIP++I + + DR+PTIRASL E E +L+++VALVI+VVF+FLR+ RATLIPAVAV Sbjct: 307 LRASIPASIQLNIAQDRSPTIRASLDEVERSLVIAVALVILVVFIFLRSGRATLIPAVAV 366 Query: 367 PVSLIGTFGIMYLAGFSLDNLSLMALTIATGFVVDDAIVVLENISRYIEAGMKPYKAALL 426 PVSLIGTF MYL GFSL+NLSLMALTIATGFVVDDAIVVLENISR++EAG+KP AAL Sbjct: 367 PVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENISRHLEAGVKPKVAALR 426 Query: 427 GAREVGFTVLSMSISLIAVFIPILMMEGIVGRLFREFAITLSVAILVSLVVSLTTTPMMC 486 G REVGFTVLSMSISL+AVFIP+L+M G+ GRLFREFA+TLSVAI +SLV+SLT TPMMC Sbjct: 427 GVREVGFTVLSMSISLVAVFIPLLLMAGLPGRLFREFAVTLSVAIGISLVISLTLTPMMC 486 Query: 487 AQLLRHDPEGDAARRERRHPWLQKIADQSAAIFEDMLLA----YERTLAWALRAAPLMML 542 A LLR P+G R F +LLA Y R+L WAL +M+ Sbjct: 487 AWLLRSHPKGQQQRIRG---------------FGKVLLAIQQGYGRSLNWALSHTRWVMV 531 Query: 543 ILLGTIALNVYLYKAIPKGFFPQQDTGRLVGGIRGDQAISFQAMRTKLNEFIDIVKADPA 602 +LL TIALNV+LY +IPK FFP+QDTGR++G I+ DQ+ISFQ+M+ KL +F+ IV ADPA Sbjct: 532 VLLSTIALNVWLYISIPKTFFPEQDTGRMMGFIQADQSISFQSMQQKLKDFMQIVGADPA 591 Query: 603 VSDVVAFTGGQRRNGGFMYVTLKPLSERKDSADKIVARLRIKTAKVAGARVFLVPVQDIR 662 V V FTGG R N G M+++LKPLSER+++A +++ RLR K AK GA +FL VQDIR Sbjct: 592 VDSVTGFTGGSRTNSGSMFISLKPLSERQETAQQVITRLRGKLAKEPGANLFLSSVQDIR 651 Query: 663 IGARQSDSQYEYSLKSDDVGLLRIWEPKIRLALSNLKELEDISTDQQDNGLQTTLTIDRE 722 +G R S++ Y+++L +DD+ LR WEPK+R AL+ L +L D+++DQQD G + LT DRE Sbjct: 652 VGGRHSNAAYQFTLLADDLAALREWEPKVRAALAKLPQLADVNSDQQDKGAEMALTYDRE 711 Query: 723 TAMRAGVTPQLIDSTLSDLFGQRQISTIYSGMNQYHVVMEAAPQYWQSPETLRDTYVSLA 782 T R G+ ++ L++ FGQRQISTIY +NQY VVME AP+Y Q +L +V Sbjct: 712 TMARLGIDVSEANALLNNAFGQRQISTIYQPLNQYKVVMEVAPEYTQDVSSLDKMFV--- 768 Query: 783 GSSNLSPTTSSLSTPPALSAAGKLNANTGLAQTISTAASTQIPLAAFSRFEPTTTALSVS 842 +N+N IPL+ F++++P L+V+ Sbjct: 769 -----------------------INSN-----------GQSIPLSYFAKWQPANAPLAVN 794 Query: 843 HEGQFVASTLSFNLAEGVSLSQATAAIDRAMAQLGVPTSVLGTFAGTANAFQASTSSQPI 902 H+G AST+SFNL +G SLS+ATAA++RAM +LGVP++V G FAGTA FQ + SQ Sbjct: 795 HQGLSAASTISFNLPDGGSLSEATAAVERAMTELGVPSTVRGAFAGTAQVFQETLKSQLW 854 Query: 903 LILTALLAVYIVLGILYESLIHPITIISTLPSAGVGALLALMVTGTDFSLIALIGVILLI 962 LI+ A+ VYIVLGILYES +HP+TI+STLPSAGVGALLAL + FSLIALIG++LLI Sbjct: 855 LIMAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFDAPFSLIALIGIMLLI 914 Query: 963 GIVKKNAIMMVDFAIDAERNRGMSPRDAIFEACKLRFRPIMMTTMAALLGAIPLAIGHGD 1022 GIVKKNAIMMVDFA+DA+RN +S R+AIF+A LRFRPI+MTT+AAL GA+PL + GD Sbjct: 915 GIVKKNAIMMVDFALDAQRNGNISAREAIFQASLLRFRPIIMTTLAALFGALPLVLSSGD 974 Query: 1023 GAELRQPLGISIVGGLVVSQLLTLYTTPVVYLYMERLSAWSRRRFGRK 1070 GAELRQPLGI+IVGGLVVSQLLTLYTTPV+YLY +RL R RF ++ Sbjct: 975 GAELRQPLGITIVGGLVVSQLLTLYTTPVIYLYFDRL----RNRFSKQ 1018 >ECs2884 [V] COG0841 Cation/multidrug efflux pump Ecs Escherichia coli O157:H7 Length = 1025 Score = 1233 bits (3191), Expect = 0.0, Method: Compositional matrix adjust. Identities = 641/1066 (60%), Positives = 808/1066 (75%), Gaps = 52/1066 (4%) Query: 7 FIKRPIATTLLTIGIALAGMVAFRLLPVSPLPQVDYPTISISASLPGASPETMAATVATP 66 FI RP+AT LL++ I L G++ FR+LPV+PLPQVD+P I +SASLPGASPETMA++VATP Sbjct: 7 FIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPVIMVSASLPGASPETMASSVATP 66 Query: 67 LERAMGAIAGVTEMTSTSSQNSTRITLQFDLNRDIDGAARDVQAALNAARNLLPTGMPSN 126 LER++G IAGV+EMTS+SS STRI LQFD +RDI+GAARDVQAA+NAA++LLP+GMPS Sbjct: 67 LERSLGRIAGVSEMTSSSSLGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMPSR 126 Query: 127 PTYRKVNPADAPILILAMTSDTMTQGQMYDAADSIVAQKLSQVRGVGQVSVGGSSQPAVR 186 PTYRK NP+DAPI+IL +TSDT +QG++YD A + +A +SQ+ GVG V VGGSS PAVR Sbjct: 127 PTYRKANPSDAPIMILTLTSDTYSQGELYDFASTQLAPTISQIDGVGDVDVGGSSLPAVR 186 Query: 187 IELNPTALNKYGIGSADVRTAVAATNANRPKGLLEDDGRNWQIYANDQAKTAAEYAPLIV 246 + LNP AL G+ DVRTA++ N +P+G LED WQI ND+ KTAAEY PLI+ Sbjct: 187 VGLNPQALFNQGVSLDDVRTAISNANVRKPQGALEDGTHRWQIQTNDELKTAAEYQPLII 246 Query: 247 SYRNGTPVRVQDVAEVRDSVADVRNAGSSNGKPSVLIIINRQPGANIIETVDNVRALLPQ 306 Y NG VR+ DVA V DSV DVRNAG +N KP++L++I + P ANII+TVD++RA LP+ Sbjct: 247 HYNNGGAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDSIRAKLPE 306 Query: 307 LQASIPSAIDMKVVLDRTPTIRASLKETEFTLMLSVALVIMVVFLFLRNARATLIPAVAV 366 LQ +IP+AID+++ DR+PTIRASL+E E TL++SVALVI+VVFLFLR+ RAT+IPAVAV Sbjct: 307 LQETIPAAIDLQIAQDRSPTIRASLEEVEQTLIISVALVILVVFLFLRSGRATIIPAVAV 366 Query: 367 PVSLIGTFGIMYLAGFSLDNLSLMALTIATGFVVDDAIVVLENISRYIEAGMKPYKAALL 426 PVSLIGTF MYL GFSL+NLSLMALTIATGFVVDDAIVVLENI+R++EAGMKP +AAL Sbjct: 367 PVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENIARHLEAGMKPLQAALQ 426 Query: 427 GAREVGFTVLSMSISLIAVFIPILMMEGIVGRLFREFAITLSVAILVSLVVSLTTTPMMC 486 G REVGFTVLSMS+SL+AVF+P+L+M G+ GRL REFA+TLSVAI +SL+VSLT TPMMC Sbjct: 427 GTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISLLVSLTLTPMMC 486 Query: 487 AQLLRHDPEGDAARRERRHPWLQKIADQSAAIFEDMLLAYERTLAWALRAAPLMMLILLG 546 +L+ A + R L+ A+ + Y ++L W L L+ ++LLG Sbjct: 487 GWMLK-------ASKPREQKRLRGFGRMLVALQQ----GYGKSLKWVLNHTRLVGMVLLG 535 Query: 547 TIALNVYLYKAIPKGFFPQQDTGRLVGGIRGDQAISFQAMRTKLNEFIDIVKADPAVSDV 606 TIALN++LY +IPK FFP+QDTG L+GGI+ DQ+ISFQAMR KL +F+ I++ DPAV +V Sbjct: 536 TIALNIWLYISIPKTFFPEQDTGVLMGGIQADQSISFQAMRGKLQDFMKIIRDDPAVDNV 595 Query: 607 VAFTGGQRRNGGFMYVTLKPLSERKDSADKIVARLRIKTAKVAGARVFLVPVQDIRIGAR 666 FTGG R N G M++TLKP ER ++A +I+ RLR+K AK GA +FL+ VQDIR+G R Sbjct: 596 TGFTGGSRVNSGMMFITLKPRDERSETAQQIIDRLRVKLAKEPGANLFLMAVQDIRVGGR 655 Query: 667 QSDSQYEYSLKSDDVGLLRIWEPKIRLALSNLKELEDISTDQQDNGLQTTLTIDRETAMR 726 QS++ Y+Y+L SDD+ LR WEPKIR L+ L EL D+++DQQDNG + L DR+T R Sbjct: 656 QSNASYQYTLLSDDLAALREWEPKIRKKLATLPELADVNSDQQDNGAEMNLVYDRDTMAR 715 Query: 727 AGVTPQLIDSTLSDLFGQRQISTIYSGMNQYHVVMEAAPQYWQSPETLRDTYVSLAGSSN 786 G+ Q +S L++ FGQRQISTIY MNQY VVME P+Y Q L +V Sbjct: 716 LGIDVQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRYTQDISALEKMFV------- 768 Query: 787 LSPTTSSLSTPPALSAAGKLNANTGLAQTISTAASTQIPLAAFSRFEPTTTALSVSHEGQ 846 +N N G A IPL+ F++++P LSV+H+G Sbjct: 769 -------------------IN-NEGKA----------IPLSYFAKWQPANAPLSVNHQGL 798 Query: 847 FVASTLSFNLAEGVSLSQATAAIDRAMAQLGVPTSVLGTFAGTANAFQASTSSQPILILT 906 AST+SFNL G SLS A+AAIDRAM QLGVP++V G+FAGTA FQ + +SQ ILI+ Sbjct: 799 SAASTISFNLPTGKSLSDASAAIDRAMTQLGVPSTVRGSFAGTAQVFQETMNSQVILIIA 858 Query: 907 ALLAVYIVLGILYESLIHPITIISTLPSAGVGALLALMVTGTDFSLIALIGVILLIGIVK 966 A+ VYIVLGILYES +HP+TI+STLPSAGVGALLAL + FSLIALIG++LLIGIVK Sbjct: 859 AIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVK 918 Query: 967 KNAIMMVDFAIDAERNRGMSPRDAIFEACKLRFRPIMMTTMAALLGAIPLAIGHGDGAEL 1026 KNAIMMVDFA++A+R+ ++P++AIF+AC LRFRPIMMTT+AAL GA+PL + GDG+EL Sbjct: 919 KNAIMMVDFALEAQRHGNLTPQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGSEL 978 Query: 1027 RQPLGISIVGGLVVSQLLTLYTTPVVYLYMERLSAWSRRRFGRKNK 1072 RQPLGI+IVGGLV+SQLLTLYTTPVVYL+ +RL R RF RK+K Sbjct: 979 RQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRL----RLRFSRKSK 1020 >yegO [V] COG0841 Cation/multidrug efflux pump Eco Escherichia coli K12 Length = 1025 Score = 1230 bits (3182), Expect = 0.0, Method: Compositional matrix adjust. Identities = 641/1066 (60%), Positives = 807/1066 (75%), Gaps = 52/1066 (4%) Query: 7 FIKRPIATTLLTIGIALAGMVAFRLLPVSPLPQVDYPTISISASLPGASPETMAATVATP 66 FI RP+AT LL++ I L G++ FR+LPV+PLPQVD+P I +SASLPGASPETMA++VATP Sbjct: 7 FIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPVIIVSASLPGASPETMASSVATP 66 Query: 67 LERAMGAIAGVTEMTSTSSQNSTRITLQFDLNRDIDGAARDVQAALNAARNLLPTGMPSN 126 LER++G IAGV+EMTS+SS STRI LQFD +RDI+GAARDVQAA+NAA++LLP+GMPS Sbjct: 67 LERSLGRIAGVSEMTSSSSLGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMPSR 126 Query: 127 PTYRKVNPADAPILILAMTSDTMTQGQMYDAADSIVAQKLSQVRGVGQVSVGGSSQPAVR 186 PTYRK NP+DAPI+IL +TSDT +QG++YD A + +A +SQ+ GVG V VGGSS PAVR Sbjct: 127 PTYRKANPSDAPIMILTLTSDTYSQGELYDFASTQLAPTISQIDGVGDVDVGGSSLPAVR 186 Query: 187 IELNPTALNKYGIGSADVRTAVAATNANRPKGLLEDDGRNWQIYANDQAKTAAEYAPLIV 246 + LNP AL G+ DVRTAV+ N +P+G LED WQI ND+ KTAAEY PLI+ Sbjct: 187 VGLNPQALFNQGVSLDDVRTAVSNANVRKPQGALEDGTHRWQIQTNDELKTAAEYQPLII 246 Query: 247 SYRNGTPVRVQDVAEVRDSVADVRNAGSSNGKPSVLIIINRQPGANIIETVDNVRALLPQ 306 Y NG VR+ DVA V DSV DVRNAG +N KP++L++I + P ANII+TVD++RA LP+ Sbjct: 247 HYNNGGAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDSIRAKLPE 306 Query: 307 LQASIPSAIDMKVVLDRTPTIRASLKETEFTLMLSVALVIMVVFLFLRNARATLIPAVAV 366 LQ +IP+AID+++ DR+PTIRASL+E E TL++SVALVI+VVFLFLR+ RAT+IPAV+V Sbjct: 307 LQETIPAAIDLQIAQDRSPTIRASLEEVEQTLIISVALVILVVFLFLRSGRATIIPAVSV 366 Query: 367 PVSLIGTFGIMYLAGFSLDNLSLMALTIATGFVVDDAIVVLENISRYIEAGMKPYKAALL 426 PVSLIGTF MYL GFSL+NLSLMALTIATGFVVDDAIVVLENI+R++EAGMKP +AAL Sbjct: 367 PVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENIARHLEAGMKPLQAALQ 426 Query: 427 GAREVGFTVLSMSISLIAVFIPILMMEGIVGRLFREFAITLSVAILVSLVVSLTTTPMMC 486 G REVGFTVLSMS+SL+AVF+P+L+M G+ GRL REFA+TLSVAI +SL+VSLT TPMMC Sbjct: 427 GTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISLLVSLTLTPMMC 486 Query: 487 AQLLRHDPEGDAARRERRHPWLQKIADQSAAIFEDMLLAYERTLAWALRAAPLMMLILLG 546 +L+ A + R L+ A+ + Y ++L W L L+ ++LLG Sbjct: 487 GWMLK-------ASKPREQKRLRGFGRMLVALQQ----GYGKSLKWVLNHTRLVGVVLLG 535 Query: 547 TIALNVYLYKAIPKGFFPQQDTGRLVGGIRGDQAISFQAMRTKLNEFIDIVKADPAVSDV 606 TIALN++LY +IPK FFP+QDTG L+GGI+ DQ+ISFQAMR KL +F+ I++ DPAV +V Sbjct: 536 TIALNIWLYISIPKTFFPEQDTGVLMGGIQADQSISFQAMRGKLQDFMKIIRDDPAVDNV 595 Query: 607 VAFTGGQRRNGGFMYVTLKPLSERKDSADKIVARLRIKTAKVAGARVFLVPVQDIRIGAR 666 FTGG R N G M++TLKP ER ++A +I+ RLR+K AK GA +FL+ VQDIR+G R Sbjct: 596 TGFTGGSRVNSGMMFITLKPRDERSETAQQIIDRLRVKLAKEPGANLFLMAVQDIRVGGR 655 Query: 667 QSDSQYEYSLKSDDVGLLRIWEPKIRLALSNLKELEDISTDQQDNGLQTTLTIDRETAMR 726 QS++ Y+Y+L SDD+ LR WEPKIR L+ L EL D+++DQQDNG + L DR+T R Sbjct: 656 QSNASYQYTLLSDDLAALREWEPKIRKKLATLPELADVNSDQQDNGAEMNLVYDRDTMAR 715 Query: 727 AGVTPQLIDSTLSDLFGQRQISTIYSGMNQYHVVMEAAPQYWQSPETLRDTYVSLAGSSN 786 G+ Q +S L++ FGQRQISTIY MNQY VVME P+Y Q L +V Sbjct: 716 LGIDVQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRYTQDISALEKMFV------- 768 Query: 787 LSPTTSSLSTPPALSAAGKLNANTGLAQTISTAASTQIPLAAFSRFEPTTTALSVSHEGQ 846 +N N G A IPL+ F++++P LSV+H+G Sbjct: 769 -------------------IN-NEGKA----------IPLSYFAKWQPANAPLSVNHQGL 798 Query: 847 FVASTLSFNLAEGVSLSQATAAIDRAMAQLGVPTSVLGTFAGTANAFQASTSSQPILILT 906 AST+SFNL G SLS A+AAIDRAM QLGVP++V G+FAGTA FQ + +SQ ILI+ Sbjct: 799 SAASTISFNLPTGKSLSDASAAIDRAMTQLGVPSTVRGSFAGTAQVFQETMNSQVILIIA 858 Query: 907 ALLAVYIVLGILYESLIHPITIISTLPSAGVGALLALMVTGTDFSLIALIGVILLIGIVK 966 A+ VYIVLGILYES +HP+TI+STLPSAGVGALLAL + FSLIALIG++LLIGIVK Sbjct: 859 AIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVK 918 Query: 967 KNAIMMVDFAIDAERNRGMSPRDAIFEACKLRFRPIMMTTMAALLGAIPLAIGHGDGAEL 1026 KNAIMMVDFA++A+R+ ++P++AIF+AC LRFRPIMMTT+AAL GA+PL + GDG+EL Sbjct: 919 KNAIMMVDFALEAQRHGNLTPQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGSEL 978 Query: 1027 RQPLGISIVGGLVVSQLLTLYTTPVVYLYMERLSAWSRRRFGRKNK 1072 RQPLGI+IVGGLV+SQLLTLYTTPVVYL+ +RL R RF RK K Sbjct: 979 RQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRL----RLRFSRKPK 1020 >ZyegO [V] COG0841 Cation/multidrug efflux pump EcZ Escherichia coli O157:H7 EDL933 Length = 1025 Score = 1227 bits (3174), Expect = 0.0, Method: Compositional matrix adjust. Identities = 639/1066 (59%), Positives = 805/1066 (75%), Gaps = 52/1066 (4%) Query: 7 FIKRPIATTLLTIGIALAGMVAFRLLPVSPLPQVDYPTISISASLPGASPETMAATVATP 66 FI RP+AT LL++ I L G++ FR+LPV+PLPQVD+P I +SASLPGASPETMA++VATP Sbjct: 7 FIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPVIMVSASLPGASPETMASSVATP 66 Query: 67 LERAMGAIAGVTEMTSTSSQNSTRITLQFDLNRDIDGAARDVQAALNAARNLLPTGMPSN 126 LER++G IAGV+EMTS+SS STRI LQFD RDI+ AARDV AA+NAA++LLP+GMPS Sbjct: 67 LERSLGRIAGVSEMTSSSSLGSTRIILQFDFXRDINXAARDVXAAINAAQSLLPSGMPSR 126 Query: 127 PTYRKVNPADAPILILAMTSDTMTQGQMYDAADSIVAQKLSQVRGVGQVSVGGSSQPAVR 186 PTYRK NP+DAPI+IL +TSDT +QG++YD A + +A +SQ+ GVG V VGGSS PAVR Sbjct: 127 PTYRKANPSDAPIMILTLTSDTYSQGELYDFASTQLAPTISQIDGVGDVDVGGSSLPAVR 186 Query: 187 IELNPTALNKYGIGSADVRTAVAATNANRPKGLLEDDGRNWQIYANDQAKTAAEYAPLIV 246 + LNP AL G+ DVRTA++ N +P+G LED WQI ND+ KTAAEY PLI+ Sbjct: 187 VGLNPQALFNQGVSLDDVRTAISNANVRKPQGALEDGTHRWQIQTNDELKTAAEYQPLII 246 Query: 247 SYRNGTPVRVQDVAEVRDSVADVRNAGSSNGKPSVLIIINRQPGANIIETVDNVRALLPQ 306 Y NG VR+ DVA V DSV DVRNAG +N KP++L++I + P ANII+TVD++RA LP+ Sbjct: 247 HYNNGGAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQTVDSIRAKLPE 306 Query: 307 LQASIPSAIDMKVVLDRTPTIRASLKETEFTLMLSVALVIMVVFLFLRNARATLIPAVAV 366 LQ +IP+AID+++ DR+PTIRASL+E E TL++SVALVI+VVFLFLR+ RAT+IPAVAV Sbjct: 307 LQETIPAAIDLQIAQDRSPTIRASLEEVEQTLIISVALVILVVFLFLRSGRATIIPAVAV 366 Query: 367 PVSLIGTFGIMYLAGFSLDNLSLMALTIATGFVVDDAIVVLENISRYIEAGMKPYKAALL 426 PVSLIGTF MYL GFSL+NLSLMALTIATGFVVDDAIVVLENI+R++EAGMKP +AAL Sbjct: 367 PVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENIARHLEAGMKPLQAALQ 426 Query: 427 GAREVGFTVLSMSISLIAVFIPILMMEGIVGRLFREFAITLSVAILVSLVVSLTTTPMMC 486 G REVGFTVLSMS+SL+AVF+P+L+M G+ GRL REFA+TLSVAI +SL+VSLT TPMMC Sbjct: 427 GTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGISLLVSLTLTPMMC 486 Query: 487 AQLLRHDPEGDAARRERRHPWLQKIADQSAAIFEDMLLAYERTLAWALRAAPLMMLILLG 546 +L+ A + R L+ A+ + Y ++L W L L+ ++LLG Sbjct: 487 GWMLK-------ASKPREQKRLRGFGRMLVALQQ----GYGKSLKWVLNHTRLVGMVLLG 535 Query: 547 TIALNVYLYKAIPKGFFPQQDTGRLVGGIRGDQAISFQAMRTKLNEFIDIVKADPAVSDV 606 TIALN++LY +IPK FFP+QDTG L+GGI+ DQ+ISFQAMR KL +F+ I++ DPAV +V Sbjct: 536 TIALNIWLYISIPKTFFPEQDTGVLMGGIQADQSISFQAMRGKLQDFMKIIRDDPAVDNV 595 Query: 607 VAFTGGQRRNGGFMYVTLKPLSERKDSADKIVARLRIKTAKVAGARVFLVPVQDIRIGAR 666 FTGG R N G M++TLKP ER ++A +I+ RLR+K AK GA +FL+ VQDIR+G R Sbjct: 596 TGFTGGSRVNSGMMFITLKPRDERSETAQQIIDRLRVKLAKEPGANLFLMAVQDIRVGGR 655 Query: 667 QSDSQYEYSLKSDDVGLLRIWEPKIRLALSNLKELEDISTDQQDNGLQTTLTIDRETAMR 726 QS++ Y+Y+L SDD+ LR WEPKIR L+ L EL D+++DQQDNG + L DR+T R Sbjct: 656 QSNASYQYTLLSDDLAALREWEPKIRKKLATLPELADVNSDQQDNGAEMNLVYDRDTMAR 715 Query: 727 AGVTPQLIDSTLSDLFGQRQISTIYSGMNQYHVVMEAAPQYWQSPETLRDTYVSLAGSSN 786 G+ Q +S L++ FGQRQISTIY MNQY VVME P+Y Q L +V Sbjct: 716 LGIDVQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRYTQDISALEKMFV------- 768 Query: 787 LSPTTSSLSTPPALSAAGKLNANTGLAQTISTAASTQIPLAAFSRFEPTTTALSVSHEGQ 846 +N N G A IPL+ F++++P LSV+H+G Sbjct: 769 -------------------IN-NEGKA----------IPLSYFAKWQPANAPLSVNHQGL 798 Query: 847 FVASTLSFNLAEGVSLSQATAAIDRAMAQLGVPTSVLGTFAGTANAFQASTSSQPILILT 906 AST+SFNL G SLS A+AAIDRAM QLGVP++V G+FAGTA FQ + +SQ ILI+ Sbjct: 799 SAASTISFNLPTGKSLSDASAAIDRAMTQLGVPSTVRGSFAGTAQVFQETMNSQVILIIA 858 Query: 907 ALLAVYIVLGILYESLIHPITIISTLPSAGVGALLALMVTGTDFSLIALIGVILLIGIVK 966 A+ VYIVLGILYES +HP+TI+STLPSAGVGALLAL + FSLIALIG++LLIGIVK Sbjct: 859 AIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVK 918 Query: 967 KNAIMMVDFAIDAERNRGMSPRDAIFEACKLRFRPIMMTTMAALLGAIPLAIGHGDGAEL 1026 KNAIMMVDFA++A+R+ ++P++AIF+AC LRFRPIMMTT+AAL GA+PL + GDG+EL Sbjct: 919 KNAIMMVDFALEAQRHGNLTPQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGSEL 978 Query: 1027 RQPLGISIVGGLVVSQLLTLYTTPVVYLYMERLSAWSRRRFGRKNK 1072 RQPLGI+IVGGLV+SQLLTLYTTPVVYL+ +RL R RF RK+K Sbjct: 979 RQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRL----RLRFSRKSK 1020