BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0032.0067.p (779 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value YPO0970_1 [S] COG3501 Uncharacterized protein conserved in bacte... 325 3e-88 YPO1472_1 [S] COG3501 Uncharacterized protein conserved in bacte... 320 9e-87 PA5090 [S] COG3501 Uncharacterized protein conserved in bacteria... 158 6e-38 PA5266 [S] COG3501 Uncharacterized protein conserved in bacteria... 147 1e-34 PA3294 [S] COG3501 Uncharacterized protein conserved in bacteria... 143 1e-33 >YPO0970_1 [S] COG3501 Uncharacterized protein conserved in bacteria Ype Yersinia pestis Length = 571 Score = 325 bits (832), Expect = 3e-88, Method: Compositional matrix adjust. Identities = 206/578 (35%), Positives = 307/578 (53%), Gaps = 34/578 (5%) Query: 1 MSMILPSQAYE-----LKLAPHPAPTSVLRFNGRDAISELYRYDVEFTSSVNDI-PMDQV 54 M+ LP+ ++ L + A VL F G +++S+ + YD++FTS+ I P + Sbjct: 1 MNTTLPTLRFDHSHHKLVVRDSTAAVDVLGFEGHESLSQPFCYDIQFTSADKAIDPATML 60 Query: 55 VGRPAKFIISPVDPNMDYLRRMFGDNAEQFSKMPAAYTIHGIVTEFDELSSSADQTHYRI 114 + + + +P + FG +Q ++ I G+VT F LS+S ++ Y + Sbjct: 61 MHDASLTLAAP-------MAEAFGVTVQQTQRV-----IQGVVTGFKRLSASKEECRYEL 108 Query: 115 RLEPTLADLNRGVTSRLFQKQSVEEIITDTLRHYGYRAGVDFQFKLRGQYKRREYITQYH 174 L+P LA L+R + ++Q SV +I+ LR G DF F L +Y RRE + QY Sbjct: 109 SLQPRLALLSRSHQNGIYQDMSVPQIVEKILRERHDMRGQDFVFTLAREYPRREQVMQYG 168 Query: 175 ETTFAFIQRICAEEGIWFRW--EQKKDHAVVVFGDDLDAYARKQRIVSYRRDAGLESSGI 232 E FI+R+ AE GIWFR+ + K + VV F DD Y + + + +G+ SG+ Sbjct: 169 EDDLTFIRRLLAEVGIWFRFTADPKLNIDVVEFYDDQRFYQQGLTLQAVP-PSGMHDSGM 227 Query: 233 DAIKTLEKRTKRVPEAVRLHDYNHRQAGVSLLVEQSAARDDKTTSGVDYRWGEHYET--- 289 +++ L + V ++V DYN+R A + R D TT G Y + ++Y T Sbjct: 228 ESVWDLSSAHQVVEKSVSTGDYNYRTATADMTAGADITRGDTTTYGEAYHYADNYLTAGS 287 Query: 290 ------PEEGQRTAQLRHEEFLSRQISFKGTGNPFWLEAGEVMRLDTNPSDAQ--HGIFI 341 E G A+LRHE +L+ Q F G N L G+ +++ N AQ G+ + Sbjct: 288 EGREPESESGAFYARLRHERYLNNQARFAGVANAAALSPGQELKVTGNDVPAQFGKGVIV 347 Query: 342 TAVESEGGRGQAFWLSFEGIPSDRVWRTSVHSIVRPVIDGILPARITSPG-DYKYAYLNE 400 T + S R +++ + FE IP + I +P + G LPAR+TS + Y ++++ Sbjct: 348 TRITSHARRDRSYEVHFEAIPYSEEYCFRPILINKPKMAGTLPARVTSTTVNDTYGHIDK 407 Query: 401 QGWYVIKLPFDLDEWSPGGSSRPVRFAKPYSGDDYGHHFPLIDGAEVAIIHTAGDPDRPV 460 G Y + L FD D W G S VR A+PY+GD YG H PL+ G EVAI G+PDRP Sbjct: 408 DGRYRVNLMFDRDSWEQGYESLWVRQARPYAGDSYGLHLPLLAGTEVAIAFEDGNPDRPY 467 Query: 461 IIGALHDSLHPDLVTSHNNTRNIVRTAAQNELRMEDKEGVEHIHLTTPF-QTSELNLGHL 519 I LHDS H D VT N RN++RT + N+LR+ED+ G EHI L+T + S+LNLGHL Sbjct: 468 IASVLHDSAHGDHVTISNYKRNVLRTPSNNKLRLEDERGKEHIKLSTEYGGKSQLNLGHL 527 Query: 520 VDADRAERGRGAELRTDGHAVVRGAKGVLVSAEEQAGA 557 VD ++ RG G ELRTD +R KG+ +SA+ QA A Sbjct: 528 VDNEKQPRGEGFELRTDSFGALRAEKGIFISADGQAKA 565 >YPO1472_1 [S] COG3501 Uncharacterized protein conserved in bacteria Ype Yersinia pestis Length = 571 Score = 320 bits (820), Expect = 9e-87, Method: Compositional matrix adjust. Identities = 211/580 (36%), Positives = 312/580 (53%), Gaps = 38/580 (6%) Query: 1 MSMILPS-----QAYELKLAPHPAPTSVLRFNGRDAISELYRYDVEFTSSVNDIPMDQVV 55 M+ LP+ ++L + A VL F G +++S+ + YD++FTS+ D+ + Sbjct: 1 MNTFLPTIRFDHSHHKLVVRDSTAAVDVLGFEGHESLSQPFCYDIQFTSA------DKAI 54 Query: 56 GRPAKFIISPVDPNMDY-LRRMFGDNAEQFSKMPAAYTIHGIVTEFDELSSSADQTHYRI 114 G PA ++ + + FG +Q ++ I G+VT F LS+S ++ Y + Sbjct: 55 G-PATMLMHDASLTLAAPMAEAFGVTVQQTQRV-----IQGVVTGFKRLSASKEECRYEL 108 Query: 115 RLEPTLADLNRGVTSRLFQKQSVEEIITDTLRHYGYRAGVDFQFKLRGQYKRREYITQYH 174 L+P LA L+R + ++Q SV +I+ LR G DF F L +Y RRE + QY Sbjct: 109 SLQPRLALLSRSHQNGIYQDMSVPQIVEKILRERHDMRGQDFVFTLAREYPRREQVMQYG 168 Query: 175 ETTFAFIQRICAEEGIWFRW--EQKKDHAVVVFGDDLDAYARKQRIVSYRRDAGLESSGI 232 E FI+R+ AE GIWFR+ + K + VV F DD Y + + + +G+ SG+ Sbjct: 169 EDDLTFIRRLLAEVGIWFRFTADPKLNIDVVEFYDDQRFYQQGLTLQAVP-PSGMHDSGM 227 Query: 233 DAIKTLEKRTKRVPEAVRLHDYNHRQAGVSLLVEQSAARDDKTTSGVDYRWGEHYET--- 289 +++ L + V ++V DYN+R A L R D TT G Y + ++Y T Sbjct: 228 ESVWDLSSAHQVVEKSVSTGDYNYRTATADLTAGADITRGDTTTYGEAYHYADNYLTAGS 287 Query: 290 ------PEEGQRTAQLRHEEFLSRQISFKGTGNPFWLEAGEVMRLDTNPSDAQ--HGIFI 341 E G A+LRHE +L+ Q F G N L G+ + + N AQ G+ I Sbjct: 288 EGREPESESGAFYARLRHERYLNNQARFAGVANAAALAPGQELNVTGNDVPAQFGKGVII 347 Query: 342 TAVESEGGRGQAFWLSFEGIP--SDRVWRTSVHSIVRPVIDGILPARITSP-GDYKYAYL 398 T + S R +++ + FE IP D +R ++ I +P + G LPAR+TS + Y ++ Sbjct: 348 TRITSHARRDRSYEVHFEAIPYSEDYCFRPAL--IRKPTMAGTLPARVTSTTANDTYGHI 405 Query: 399 NEQGWYVIKLPFDLDEWSPGGSSRPVRFAKPYSGDDYGHHFPLIDGAEVAIIHTAGDPDR 458 ++ G Y + L FD D W G S VR A+PY+GD YG H PL+ G EVAI G+PDR Sbjct: 406 DKDGRYRVNLMFDRDSWESGYESLWVRQARPYAGDSYGLHLPLLAGTEVAIAFEDGNPDR 465 Query: 459 PVIIGALHDSLHPDLVTSHNNTRNIVRTAAQNELRMEDKEGVEHIHLTTPF-QTSELNLG 517 P I LHDS H D VT N RN++RT + N+LR+ED+ G EHI L+T + S+LNLG Sbjct: 466 PYIAYVLHDSAHGDHVTISNYKRNVLRTPSNNKLRLEDERGKEHIKLSTEYGGKSQLNLG 525 Query: 518 HLVDADRAERGRGAELRTDGHAVVRGAKGVLVSAEEQAGA 557 HLVD ++ RG G ELRTD V+R KG+ ++A+ QA A Sbjct: 526 HLVDNEKQPRGEGFELRTDSFGVLRAEKGLFITADGQAKA 565 >PA5090 [S] COG3501 Uncharacterized protein conserved in bacteria Pae Pseudomonas aeruginosa Length = 790 Score = 158 bits (399), Expect = 6e-38, Method: Compositional matrix adjust. Identities = 145/511 (28%), Positives = 219/511 (42%), Gaps = 59/511 (11%) Query: 23 VLRFNGRDAISELYRYDVEFTSSVNDIPMDQVVGRPAKFIISPVDPNMDYLRRMFGDNAE 82 VL F GR+AIS+ +R+D+E S +D+ +D ++ +PA I+SP Sbjct: 23 VLAFRGREAISQPFRFDLELVSERSDLDLDALLHQPAFLILSP----------------- 65 Query: 83 QFSKMPAAYTIHGIVTEFDELSSSADQTHYRIRLEPTLADLNRGVTSRLFQKQSVEEIIT 142 + +HG +T + S T YR LEP LA L R+FQ+ SV EII Sbjct: 66 ------SGQGVHGQLTSIAQGDSGKRLTGYRATLEPRLAYLGLCSDQRIFQRLSVPEIIG 119 Query: 143 DTLRHYGYRAGVDFQFKL-RGQYKRREYITQYHETTFAFIQRICAEEGIWFRWEQKKDHA 201 L +G A ++F+L Y REY TQY ET AF+ R+C EEGI + E Sbjct: 120 RVLEGHGILADA-YRFQLGPTPYPAREYCTQYDETDLAFLSRLCEEEGIHYHHEFSAQGH 178 Query: 202 VVVFGDDLDAYARKQRIVSYRRDAGLESSGIDAIKTLEKRTKRVPEAVRLHDYNHRQAGV 261 V+VFGDD ++ R QR V+Y +DAGL + +K R V DY+ Q + Sbjct: 179 VLVFGDDQTSFPRLQRPVAYVQDAGLVADQ-PVVKRFGVRFDTRASRVTRRDYDFEQPAL 237 Query: 262 SLLVEQSAARDDKTTSGVDYRWGEHYETPEEGQRTA------------QLRHE------- 302 + + DY + + E G+ + Q R E Sbjct: 238 QMQAAHGPQPGAQQPDLEDYDYPGRFTHRERGKHLSHRALERHRADYLQARGESDEPALL 297 Query: 303 --EFLSRQISFKGTGNPFWLEAGEVMRLDTNPSDAQHGIFITAVESEGGRGQAFWLSFEG 360 FL+ +G N WL EV+ P + I + +G Q + F Sbjct: 298 SGHFLTLSAHPRGEWNDLWL-LTEVLHEGRQPQVLEESIDSDVAQGQGDFRQGYRNHFVA 356 Query: 361 IPSDRVWRTSVHSIVRPVIDGILPARITSPGDYKYAYLNEQGWYVIKLPFDLDEWSPGGS 420 P +R + RP + G A +T P + + ++ G ++ +D + + Sbjct: 357 TPWSAHFRPPLEH-PRPRVLGCQTAVVTGPAG-ETIHCDQYGRVKVQFFWDRLGQADDNT 414 Query: 421 SRPVRFAKPYSGDDYGH-HFPLIDGAEVAIIHTAGDPDRPVIIGAL-HDSLHPDLVTSHN 478 S +R A + G YG P + G EV + GDPD+P++ G L H N Sbjct: 415 SCWLRVASNWGGKRYGGVAIPRV-GMEVLVGFLEGDPDQPLVTGCLYHSENRVPYELPQN 473 Query: 479 NTRNIVRTAAQ------NELRMEDKEGVEHI 503 TR++ +T + NELR+ED++G E I Sbjct: 474 KTRSVFKTDSYPGGGGFNELRIEDRKGQEQI 504 >PA5266 [S] COG3501 Uncharacterized protein conserved in bacteria Pae Pseudomonas aeruginosa Length = 691 Score = 147 bits (370), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 136/510 (26%), Positives = 221/510 (43%), Gaps = 62/510 (12%) Query: 23 VLRFNGRDAISELYRYDVEFTSSVNDIPMDQVVGRPAKFIISPVDPNMDYLRRMFGDNAE 82 VL F+GR+AIS+ + +D+E ++ ++ +PA + P Sbjct: 23 VLSFSGREAISQPFAFDLELVGERPVPDLESLLHKPAFLTLGP----------------- 65 Query: 83 QFSKMPAAYTIHGIVTEFDELSSSADQTHYRIRLEPTLADLNRGVTSRLFQKQSVEEIIT 142 A IHG+V + S T YRI L P LA L + R+FQ +V +I+ Sbjct: 66 ------AGNGIHGLVRSAGQGDSGKRLTRYRITLVPQLAYLAQRTNQRIFQHLTVPQIVG 119 Query: 143 DTLRHYGYRAGVDFQFKLRGQYKRREYITQYHETTFAFIQRICAEEGIWFRWEQKKDHAV 202 L +G A ++F+L +Y REY QY E+ F+QR+C EEGI F ++ + Sbjct: 120 RVLEEHGILADA-YRFQLGTRYPEREYCVQYDESDLQFVQRLCCEEGIHFHFQHSATAHL 178 Query: 203 VVFGDDLDAYARKQRIVSYRRDAGLESSGIDAIKTLEKRTKRVPEAVRLHDYNHRQAGVS 262 +VFGDD + R V+Y++D+GL + A+K R + V DY+ + ++ Sbjct: 179 LVFGDDQTVFPRLA-PVAYQQDSGLVADR-PAVKRFGVRLETRTSHVTRRDYDFEKPRLT 236 Query: 263 LLVEQSAARDDKTTSGVDYRWGEHYETPEEGQRTAQ---------------------LRH 301 L +SAAR + DY + + E G+ A+ L Sbjct: 237 L---ESAARGEARPDLEDYDYPGRFVDRERGKHLARRALERQRSDYHLAEGRSDQPLLLS 293 Query: 302 EEFLSRQISFKGTGNPFWLEAGEVMRLDTNPSDAQHGIFITAVESEGGRGQAFWLSFEGI 361 FL + N WL EV+ P + I A S Q + F+ Sbjct: 294 GHFLPLAAHPQAGWNDLWL-LTEVIHEGRQPQVLEESIVSDASASPDDFRQGYRNRFQAT 352 Query: 362 PSDRVWRTSVHSIVRPVIDGILPARITSPGDYKYAYLNEQGWYVIKLPFDLDEWSPGGSS 421 P + +R + +P I G A +T P + + + G ++ +D + + SS Sbjct: 353 PWEAFFRPP-STPPKPRILGTQSAVVTGPKGEEI-HCDRYGRVKVQFHWDREGQADDSSS 410 Query: 422 RPVRFAKPYSGDDYGH-HFPLIDGAEVAIIHTAGDPDRPVIIGALHDSLHP-DLVTSHNN 479 +R A ++G +YG P + G EV + GDPD+P++ G L HP + Sbjct: 411 CWLRVASGWAGRNYGAIAIPRV-GMEVLVTFLEGDPDQPLVTGCLFHREHPVPYELPGHK 469 Query: 480 TRNIVRTAAQ------NELRMEDKEGVEHI 503 TR++ ++ + NELR+ED++G E I Sbjct: 470 TRSVFKSLSSPGGGGYNELRIEDRKGQEQI 499 >PA3294 [S] COG3501 Uncharacterized protein conserved in bacteria Pae Pseudomonas aeruginosa Length = 688 Score = 143 bits (361), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 148/615 (24%), Positives = 257/615 (41%), Gaps = 76/615 (12%) Query: 23 VLRFNGRDAISELYRYDVEFTSSVNDIPMDQVVGRPAKFIISPVDPNMDYLRRMFGDNAE 82 VL F+G + IS YR+++E S + ++ ++ RPA +P Sbjct: 23 VLEFSGHEGISRPYRFELELVSERAGLDLEALMHRPAFLAFTP----------------- 65 Query: 83 QFSKMPAAYTIHGIVTEFDELSSSADQTHYRIRLEPTLADLNRGVTSRLFQKQSVEEIIT 142 +HG+V + + T YR+ L P LA L + R+FQ +V +I+ Sbjct: 66 ------QGQGVHGLVYGAAQGDAGKRLTRYRLTLVPHLAYLAQRNNQRIFQHLTVPQIVA 119 Query: 143 DTLRHYGYRAGVDFQFKLRGQYKRREYITQYHETTFAFIQRICAEEGIWFRWEQKKDHAV 202 L +G A ++F+L +Y REY QY E+ F+QR+CAEEGI F + + + Sbjct: 120 LILEEHGILADA-YRFQLGTRYPEREYCVQYDESDLHFVQRLCAEEGIHFHFRHSAEAHL 178 Query: 203 VVFGDDLDAYARKQRIVSYRRDAGLESSGIDAIKTLEKRTKRVPEAVRLHDYNHRQAGVS 262 +VFGDD + R R +Y D+GL + IK R DY+ + + Sbjct: 179 LVFGDDQTVFPRLGRPTAYVHDSGLVADE-PVIKRFSLRLASRTTRTTRRDYDFEKPRLL 237 Query: 263 LLVEQSAARDDKTTSGV-DYRWGEHYETPEEGQRTAQLRHEEFLSRQISFKGTGNPFWLE 321 L A D + DY + + + G+ +Q E + + +G + L Sbjct: 238 LEAGNRPAADAPAEPDLEDYDYPGRFVDRQRGKLLSQRALERHRADRRLGEGVSDQPLLV 297 Query: 322 AGEVMRLDTNPSDAQHGIF-ITAVESEGGRGQAFWLSFEGIPSD--------------RV 366 +G + + +P + ++ ++ V EG + Q E + SD R Sbjct: 298 SGHFLEIAEHPRAEWNDLWLLSEVFHEGKQPQVLE---ENVTSDTSASTDDFQQGYRNRF 354 Query: 367 WRTSVHSIVRPVIDGILP-------ARITSPGDYKYAYLNEQGWYVIKLPFDLDEWSPGG 419 T RP ++ P A +T P + + + GW ++ +D + Sbjct: 355 LATPWEVFFRPPLEHPKPRVLGSQTAVVTGPPGEEI-HCDRYGWVRVQFHWDREGQGDDK 413 Query: 420 SSRPVRFAKPYSGDDYGHHFPLIDGAEVAIIHTAGDPDRPVIIGALHDSLHP-DLVTSHN 478 SS +R A ++G+ YG G EV + GDPD+P++ G ++ + HP N Sbjct: 414 SSCWLRVASGWAGNGYGGIVIPRVGMEVLVDFLEGDPDQPLVSGCVYHAAHPVPYELPAN 473 Query: 479 NTRNIVRTAAQ------NELRMEDKEGVEHIHLTTPFQTSE-------LNLGHLVDADRA 525 TR++ ++ + NELR+ED++G E I + E + +GH D Sbjct: 474 QTRSVFKSLSSPGGGGYNELRIEDRKGQEQIFVHAQRDWDENIEHDQKIRVGH-ERHDTV 532 Query: 526 ERGRGAELRTDGHAVVRGAKGVLVSAEEQAGAAVRQ--------LAMQGAEMTFEQAEQ- 576 E +E + + H V G + V + A++ Q LA G E+ + ++ Sbjct: 533 EANSYSEFKAEEHHTVHGERKVELKADDHLTVGDSQHVKLGRAYLARAGREIHLKAGQKM 592 Query: 577 IMQTLNESTKTANAA 591 +++ +E T TA + Sbjct: 593 VIEADSELTVTAGGS 607