BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0032.0045.p (548 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp1047 [GEPR] COG0477 Permeases of the major facilitator superf... 735 0.0 AGl343 [GEPR] COG0477 Permeases of the major facilitator superfa... 637 0.0 NMA1574 [GEPR] COG0477 Permeases of the major facilitator superf... 486 e-137 NMB1362 [GEPR] COG0477 Permeases of the major facilitator superf... 481 e-135 BH2528 [GEPR] COG0477 Permeases of the major facilitator superfa... 272 1e-72 >RSp1047 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 549 Score = 735 bits (1898), Expect = 0.0, Method: Compositional matrix adjust. Identities = 378/543 (69%), Positives = 448/543 (82%), Gaps = 3/543 (0%) Query: 5 FLNKEHTVAKPGFNRWLVPPAALAIHLCIGMAYGFSVFWLPLSKALGVTAPIACGADIGF 64 F ++E TVA GFNRWLVPPAALAIHLCIGMAYGFSVFWLPLS+ALG+T CGAD+ Sbjct: 9 FFSRERTVAAVGFNRWLVPPAALAIHLCIGMAYGFSVFWLPLSRALGITQSHTCGADVSL 68 Query: 65 FAQVFSSTCDWKISMLGWMYTMFFVLLGISAALWGGWLEHAGPRKAGVVAAICWCGGLLI 124 A++F+++CDW+IS LGWMYT+FFV LG SAALWGGWLE GPRKAGVV+A+CWCGGLLI Sbjct: 69 IAELFTTSCDWRISSLGWMYTLFFVFLGASAALWGGWLERVGPRKAGVVSAVCWCGGLLI 128 Query: 125 SALGVKTHQIWLMWLGSGVIGGVGLGLGYISPVSTLIKWFPDRRGMATGMAIMGFGGGAL 184 SA GV+THQ+W++W+GSGVIGG+GLGLGYISPVSTLIKWFPD+RGMATGMAIMGFGGGA+ Sbjct: 129 SAFGVQTHQLWMLWIGSGVIGGIGLGLGYISPVSTLIKWFPDKRGMATGMAIMGFGGGAM 188 Query: 185 VGTPLADALMKKFASPTSVGVWETFVVMAVIYFVFMMAGAFGYRVPPTGWKPAGWTPPVA 244 +G PLAD LMK FAS SVGV +TF+V+A IYFVFMMAGA GYRVPP GWKPAGW P A Sbjct: 189 IGAPLADRLMKLFASADSVGVSQTFIVLAAIYFVFMMAGALGYRVPPAGWKPAGWKPSPA 248 Query: 245 KSSATMITQNHVHVSKVWGIPQFWLVWLVLCLNVSAGIGVIGIASPMLQEVFGGKLLGVD 304 K++ TM+TQ HVHVS+ PQFWL+W VLCLNVSAGIGV+G+ASP+LQEVFGGKLLGV Sbjct: 249 KANDTMVTQRHVHVSQAVKTPQFWLIWAVLCLNVSAGIGVLGMASPLLQEVFGGKLLGVT 308 Query: 305 IGFNDLSVEQKAGIAALAAGFTGLISLFNIGGRFAWASCSDFFGRKMTYAIFFVLGFVLY 364 F +L+ QK IAA+AAGFTGL+SLFNIGGRF WAS SD GRK+TYA+FF LGFVLY Sbjct: 309 TAFTELTAAQKGQIAAIAAGFTGLLSLFNIGGRFFWASLSDRLGRKLTYAVFFALGFVLY 368 Query: 365 VSLPWSAKSGNIPLFVGAVCIILSMYGGGFATVPAYLADLFGTQMVGAIHGRLLTAWATA 424 ++PW++ + NI LF A C+ILSMYGGGFATVPAYLAD+FGTQMVGAIHGRLLTAW+TA Sbjct: 369 AAIPWTSHTSNIALFSLAFCVILSMYGGGFATVPAYLADMFGTQMVGAIHGRLLTAWSTA 428 Query: 425 GILGPVVVNYMREYQLSLGMPKNEVYNTTMYILAGMLVLGLICNLLIRPVAAKHFMTPEE 484 GILGPV+VNY+REYQ++ G+ + VY+ TM +LAG+LVLG ICNLL+RPV KHFMT + Sbjct: 429 GILGPVLVNYLREYQIAHGVARAAVYDITMMVLAGLLVLGFICNLLVRPVDPKHFMTEAQ 488 Query: 485 LAREKQLAHEKSAADAAVTAGSGDMSQIGSGGNPLFIGLAWAAVGIPLIWGITLVLQKSA 544 L ++ H +AA A + G+ + + LAWAAVG+PL WG+ + LQK+A Sbjct: 489 LDEQR---HAATAATPQANAPETSLEWQAHPGSAVAVVLAWAAVGLPLGWGVWITLQKAA 545 Query: 545 VLF 547 VLF Sbjct: 546 VLF 548 >AGl343 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 552 Score = 637 bits (1642), Expect = 0.0, Method: Compositional matrix adjust. Identities = 357/545 (65%), Positives = 422/545 (77%), Gaps = 13/545 (2%) Query: 5 FLNKEHTVAKPGFNRWLVPPAALAIHLCIGMAYGFSVFWLPLSKALGVTAPIACGADIGF 64 FL++E +A+PGFNRWLVPPAALAIHLCIGMAYGFSVFWLPLSKAL T P +C + + Sbjct: 18 FLDRERIIARPGFNRWLVPPAALAIHLCIGMAYGFSVFWLPLSKALPATDP-SC-SSLTL 75 Query: 65 FAQVFSSTCDWKISMLGWMYTMFFVLLGISAALWGGWLEHAGPRKAGVVAAICWCGGLLI 124 +F++ C+W+++ LGW+YT+FFVLLG SAA+WGGWLE GPRKAG V+A CWCGG+L+ Sbjct: 76 MGALFTTECNWRVADLGWIYTLFFVLLGCSAAIWGGWLERVGPRKAGFVSACCWCGGILV 135 Query: 125 SALGVKTHQIWLMWLGSGVIGGVGLGLGYISPVSTLIKWFPDRRGMATGMAIMGFGGGAL 184 +A+GV THQ+WLMWLG+GVIGGVGLGLGYISPVSTLIKWFPDRRGMATGMAIMGFGGGA+ Sbjct: 136 AAIGVATHQLWLMWLGAGVIGGVGLGLGYISPVSTLIKWFPDRRGMATGMAIMGFGGGAM 195 Query: 185 VGTPLADALMKKFASPTSVGVWETFVVMAVIYFVFMMAGAFGYRVPPTGWKPAGWTPPVA 244 +G PLA+ LM F + S+GVW+TFVVMA++YF FMMAGAFGYR+PP GW+P GWT P A Sbjct: 196 IGAPLANLLMNTFKTEASIGVWQTFVVMALVYFAFMMAGAFGYRIPPAGWRPEGWTAPAA 255 Query: 245 KSSATMITQNHVHVSKVWGIPQFWLVWLVLCLNVSAGIGVIGIASPMLQEVFGGKLLGVD 304 KS+ MIT HVH+ PQFWL+W VLCLNVSAGIGVIG+ASPMLQE+F G L+G+ Sbjct: 256 KSA--MITTRHVHLRDAHKTPQFWLIWAVLCLNVSAGIGVIGMASPMLQEIFAGSLIGLP 313 Query: 305 -IGFNDLSVEQKAGIAALAAGFTGLISLFNIGGRFAWASCSDFFGRKMTYAIFFVLGFVL 363 +GF DL QKA IAA+AAGFTGL+SLFNIGGRF WAS SD GRK TY FFVLG +L Sbjct: 314 GVGFADLDAGQKAQIAAIAAGFTGLLSLFNIGGRFFWASMSDKIGRKNTYFCFFVLGIIL 373 Query: 364 YVSLPWSAKSGNIPLFVGAVCIILSMYGGGFATVPAYLADLFGTQMVGAIHGRLLTAWAT 423 Y P A GN LFV A IILSMYGGGFAT+PAYLAD+FGTQ VGAIHGRLLTAWAT Sbjct: 374 YALAPTLATMGNKALFVLAFGIILSMYGGGFATIPAYLADIFGTQFVGAIHGRLLTAWAT 433 Query: 424 AGILGPVVVNYMREYQLSLGM-PKNEVYNTTMYILAGMLVLGLICNLLIRPVAAKHFMTP 482 AGI GPVVVNY+RE Q++ G+ P +Y +TMYILAGML +GLI N +RP+A K FM+ Sbjct: 434 AGIAGPVVVNYIREAQIAAGVAPGPALYTSTMYILAGMLAIGLIANAFVRPLADKWFMSD 493 Query: 483 EELAREKQLAHEKSAADAAVTAGSGDMSQIGSGGNPLFIGLAWAAVGIPLIWGITLVLQK 542 E+A + + AG IG GG LAWAAVGIPL+WG+ + ++ Sbjct: 494 AEVAALQAKTAAAN-------AGPTGSFGIGRGGLDAKAALAWAAVGIPLLWGVWVTVRS 546 Query: 543 SAVLF 547 S LF Sbjct: 547 SLALF 551 >NMA1574 [GEPR] COG0477 Permeases of the major facilitator superfamily NmA Neisseria meningitidis Z2491 Length = 513 Score = 486 bits (1250), Expect = e-137, Method: Compositional matrix adjust. Identities = 273/552 (49%), Positives = 367/552 (66%), Gaps = 49/552 (8%) Query: 4 DFLNKEHTVAKPGFNRWLVPPAALAIHLCIGMAYGFSVFWLPLSKALGVTAPIACGADIG 63 FL++E ++AKPGFNRWLVPPAALA+HL IG Y +SVF PL+K +G+T Sbjct: 2 KFLDREASIAKPGFNRWLVPPAALAVHLAIGQIYAYSVFNAPLTKLIGITE--------- 52 Query: 64 FFAQVFSSTCDWKISMLGWMYTMFFVLLGISAALWGGWLEHAGPRKAGVVAAICWCGGLL 123 S+ DWK++ +GW++++ +LG SAAL+G W+E GPRKA AA C+ G Sbjct: 53 ------SAAGDWKLTTVGWIFSIALAMLGASAALFGTWMERVGPRKAIFAAACCFSLGFF 106 Query: 124 ISALGVKTHQIWLMWLGSGVIGGVGLGLGYISPVSTLIKWFPDRRGMATGMAIMGFGGGA 183 +SA GV+TH ++L++LG+GVIGGVGLGLGYI PVSTL+KWFPD+ GMATG+AIMGFGGGA Sbjct: 107 VSAFGVRTHNLFLLYLGNGVIGGVGLGLGYIGPVSTLMKWFPDKPGMATGLAIMGFGGGA 166 Query: 184 LVGTPLADALMKKFASPTSVGVWETFVVMAVIYFVFMMAGAFGYRVPPTGWKPAGWTPPV 243 ++ +PL+ +LM F++ TSVGV ETF V+ ++Y MM GAF RVP GWKP G+T P Sbjct: 167 MLASPLSVSLMNTFSNATSVGVAETFAVLGLLYLALMMFGAFTIRVPADGWKPEGYTAP- 225 Query: 244 AKSSATMITQNHVHVSKVWGIPQFWLVWLVLCLNVSAGIGVIGIASPMLQEVFGGKLLGV 303 K+ +++ NHV+VS+ PQFWL++ VLCLNV+AGIGV+G AS M+QE+F +G Sbjct: 226 -KTQNKLVSSNHVNVSQAMKTPQFWLLFWVLCLNVTAGIGVLGQASVMIQELFSETSIG- 283 Query: 304 DIGFNDLSVEQKAGIAALAAGFTGLISLFNIGGRFAWASCSDFFGRKMTYAIFFVLGFVL 363 Q A A AAGF L+SLFN+GGRF W+S SD GRK TY IFFVLG +L Sbjct: 284 ---------RQAAVGAGAAAGFVSLLSLFNMGGRFLWSSVSDKIGRKNTYTIFFVLGSLL 334 Query: 364 YVSLPWSAKSGNIPLFVGAVCIILSMYGGGFATVPAYLADLFGTQMVGAIHGRLLTAWAT 423 Y ++P + G+ LF+ C+I+SMYGGGFA +PAYL DLFGT VGAIHGR+L AW+T Sbjct: 335 YFAVPSIGEGGSKALFIIGFCVIISMYGGGFAAIPAYLKDLFGTYQVGAIHGRILLAWST 394 Query: 424 AGILGPVVVNYMREYQLSLGMPKNEVYNTTMYILAGMLVLGLICNLLIRPVAAKHFMTPE 483 A ++GPV+VNY+R+ Q+ G+P + Y+ TMYI+AG+L++GL+CNL ++ V KH Sbjct: 395 AAVIGPVLVNYIRQSQIDSGIPAAQAYSVTMYIMAGLLIIGLLCNLAVKSVHEKH----- 449 Query: 484 ELAREKQLAHEKSAADAAVTAGSGDMSQIGSG--------GNPLFIGLAWAAVGIPLIWG 535 HEK AA + D + I G + + WA IPL +G Sbjct: 450 ---------HEKDIKTAAHSGNPDDETAISDAYLVGEKVSGGGISVWWRWALAVIPLAYG 500 Query: 536 ITLVLQKSAVLF 547 + ++ K+ LF Sbjct: 501 VVMIFVKALDLF 512 >NMB1362 [GEPR] COG0477 Permeases of the major facilitator superfamily Nme Neisseria meningitidis MC58 Length = 513 Score = 481 bits (1237), Expect = e-135, Method: Compositional matrix adjust. Identities = 272/552 (49%), Positives = 365/552 (66%), Gaps = 49/552 (8%) Query: 4 DFLNKEHTVAKPGFNRWLVPPAALAIHLCIGMAYGFSVFWLPLSKALGVTAPIACGADIG 63 FL++E ++AKPGFNRWLVPPAALA+HL IG Y +SVF PL+K +G+T Sbjct: 2 KFLDREASIAKPGFNRWLVPPAALAVHLAIGQIYAYSVFNAPLTKLIGITE--------- 52 Query: 64 FFAQVFSSTCDWKISMLGWMYTMFFVLLGISAALWGGWLEHAGPRKAGVVAAICWCGGLL 123 S+ DWK++ +GW++++ +LG SAAL+G W+E GPRKA AA C+ G Sbjct: 53 ------SAAGDWKLTTVGWIFSIALAMLGASAALFGTWMERVGPRKAIFAAACCFSLGFF 106 Query: 124 ISALGVKTHQIWLMWLGSGVIGGVGLGLGYISPVSTLIKWFPDRRGMATGMAIMGFGGGA 183 +SA GV+TH ++L++LG+GVIGGVGLGLGYI PVSTL+KWFPD+ GMATG+AIMGFGGGA Sbjct: 107 VSAFGVRTHNLFLLYLGNGVIGGVGLGLGYIGPVSTLMKWFPDKPGMATGLAIMGFGGGA 166 Query: 184 LVGTPLADALMKKFASPTSVGVWETFVVMAVIYFVFMMAGAFGYRVPPTGWKPAGWTPPV 243 ++ +PL+ +LM F++ SVGV ETF V+ ++Y MM GAF RVP GWKP G+T P Sbjct: 167 MLASPLSVSLMNTFSNAASVGVAETFAVLGLLYLALMMFGAFTIRVPADGWKPEGYTAP- 225 Query: 244 AKSSATMITQNHVHVSKVWGIPQFWLVWLVLCLNVSAGIGVIGIASPMLQEVFGGKLLGV 303 K+ +++ NHV+VS+ PQFWL++ VLCLNV+AGIGV+G AS M+QE+F +G Sbjct: 226 -KTQNKLVSSNHVNVSQAMKTPQFWLLFWVLCLNVTAGIGVLGQASVMIQELFSETSIG- 283 Query: 304 DIGFNDLSVEQKAGIAALAAGFTGLISLFNIGGRFAWASCSDFFGRKMTYAIFFVLGFVL 363 Q A A AAGF L+SLFN+GGRF W+S SD GRK TY IFFVLG +L Sbjct: 284 ---------RQAAVGAGAAAGFVSLLSLFNMGGRFLWSSVSDKIGRKNTYTIFFVLGSLL 334 Query: 364 YVSLPWSAKSGNIPLFVGAVCIILSMYGGGFATVPAYLADLFGTQMVGAIHGRLLTAWAT 423 Y ++P + G+ LF+ C+I+SMYGGGFA +PAYL DLFGT VGAIHGR+L AW+T Sbjct: 335 YFAVPSIGEGGSKALFIIGFCVIISMYGGGFAAIPAYLKDLFGTYQVGAIHGRILLAWST 394 Query: 424 AGILGPVVVNYMREYQLSLGMPKNEVYNTTMYILAGMLVLGLICNLLIRPVAAKHFMTPE 483 A ++GPV+VNY+R+ Q+ G+P + Y+ TMYI+A +L++GL+CNL ++ V KH Sbjct: 395 AAVIGPVLVNYIRQSQIDSGIPAAQAYSVTMYIMACLLIIGLLCNLAVKSVHEKH----- 449 Query: 484 ELAREKQLAHEKSAADAAVTAGSGDMSQIGSG--------GNPLFIGLAWAAVGIPLIWG 535 HEK AA + D + I G + + WA IPL +G Sbjct: 450 ---------HEKDIKTAAHSGNPDDETAISDAYLVGEKVSGGGISVWWRWALAVIPLAYG 500 Query: 536 ITLVLQKSAVLF 547 + +V K+ LF Sbjct: 501 VVMVFVKALDLF 512 >BH2528 [GEPR] COG0477 Permeases of the major facilitator superfamily Bha Bacillus halodurans Length = 419 Score = 272 bits (696), Expect = 1e-72, Method: Compositional matrix adjust. Identities = 179/465 (38%), Positives = 255/465 (54%), Gaps = 70/465 (15%) Query: 14 KPGFNRWLVPPAALAIHLCIGMAYGFSVFWLPLSKALGVTAPIACGADIGFFAQVFSSTC 73 K NRWL+ AA+ IH+ IG Y +SVF PL + G Sbjct: 2 KTTKNRWLIALAAVGIHISIGSVYAWSVFTNPLIEQFG---------------------- 39 Query: 74 DWKISMLGWMYTMFFVLLGISAALWGGWLEHAGPRKAGVVAAICWCGGLLISALGVKTHQ 133 W + + +++ LG+SAA G ++E GPRK+G+VAA + G L + L V Sbjct: 40 -WGLGEVSLTFSIAIAFLGVSAAFMGHFVEKHGPRKSGMVAASFFGLGTLGAGLAVSLES 98 Query: 134 IWLMWLGSGVIGGVGLGLGYISPVSTLIKWFPDRRGMATGMAIMGFGGGALVGTPLADAL 193 +WL++ GV+GG GLG+GYI+PVSTL+KWFPDRRG+ATG+AIMGFG +LV +P+ +A Sbjct: 99 LWLLYFSYGVLGGFGLGVGYITPVSTLVKWFPDRRGLATGLAIMGFGFASLVFSPIMNAF 158 Query: 194 MKKFASPTSVGVWETFVVMAVIYFVFMMAGAFGYRVPPTGWKPAGWTPP------VAKSS 247 + TSVG+ TF ++ +Y + M A PP GW PAG+ + K Sbjct: 159 I------TSVGIAATFFILGGLYMIIMFTAALYLEPPPQGWVPAGFKEAKTENGRLQKQD 212 Query: 248 ATMITQNHVHVSKVWGIPQFWLVWLVLCLNVSAGIGVIGIASPMLQEVFGGKLLGVDIGF 307 + +T N +K +FW +W +L +NV+ GI ++ +ASPM QE+ Sbjct: 213 LSQLTANEAVKTK-----RFWFLWTMLFINVTCGIAILAVASPMAQEI------------ 255 Query: 308 NDLSVEQKAGIAALAAGFTGLISLFNIGGRFAWASCSDFFGRKMTYAIFFVLGFVLYVSL 367 AA AA GL+ LFN GR WAS SD+ GR Y FF++ V +V L Sbjct: 256 -------TGMTAATAATMVGLMGLFNGLGRIGWASISDYIGRPNVYTAFFLIQIVAFVML 308 Query: 368 PWSAKSGNIPLFVGAVCIILSMYGGGFATVPAYLADLFGTQMVGAIHGRLLTAWATAGIL 427 P ++ LF + I++ YGGGFA++PAY+ DLFGT+ +GAIHG +LTAWA AG++ Sbjct: 309 P---SITHVLLFQVVLFFIMTCYGGGFASIPAYIGDLFGTKQLGAIHGYILTAWALAGLV 365 Query: 428 GPVVVNYMREYQLSLGMPKNEVYNTTMYILAGMLVLGLICNLLIR 472 GP++ +Y+RE Y T+YI GM ++ L +L IR Sbjct: 366 GPMIASYIRE--------TTNSYAGTLYIFTGMFIVALAVSLFIR 402