BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0032.0033.p (388 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc3059 [GEPR] COG0477 Permeases of the major facilitator superf... 520 e-147 STM0689 [GEPR] COG0477 Permeases of the major facilitator superf... 507 e-143 PA5476 [GEPR] COG0477 Permeases of the major facilitator superfa... 495 e-140 RSc3060 [GEPR] COG0477 Permeases of the major facilitator superf... 492 e-139 PA4343 [GEPR] COG0477 Permeases of the major facilitator superfa... 247 3e-65 >RSc3059 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 431 Score = 520 bits (1339), Expect = e-147, Method: Compositional matrix adjust. Identities = 249/357 (69%), Positives = 294/357 (82%) Query: 12 KHSKLSTVLRVTSGNFLEMFDFFLYGFYASYISRTLFPSDNEFVSLILTFGTFGAGFLMR 71 SK ++ RV SGNFLEM+DF +YG+YA I+ T FP+DNEF+SL+L+ TFG GFLMR Sbjct: 7 NESKARSIFRVVSGNFLEMYDFMVYGYYAKAIADTFFPADNEFLSLMLSLVTFGVGFLMR 66 Query: 72 PLGAIILGSYIDRVGRRQGLIVTLAIMAIGTLLIAFVPGYATIGITAPILVLTGRLLQGF 131 PLGA+ILG+YIDR GRR GLI+TL +MA GTLLIA VPGYATIG+ AP+LVL GRLLQGF Sbjct: 67 PLGALILGAYIDRHGRRAGLILTLGLMACGTLLIALVPGYATIGLAAPLLVLIGRLLQGF 126 Query: 132 SAGVELGGVSVYLAEMATPGNKGFYVSWQSASQQAAIMASALIGYLVSQWLSPLQISEWG 191 SAGVELGGVSVYLAE++TPG KGF+VSWQSASQQ A+M +AL+G L+S LSP ++ EWG Sbjct: 127 SAGVELGGVSVYLAEISTPGRKGFFVSWQSASQQVAVMFAALLGVLLSFQLSPKEMGEWG 186 Query: 192 WRIPFFIGCMIVPAIFIIRRSLQETEEFMARKHHPGFAEIMASIAQNWKIVVAGMMMVVM 251 WR+PF +GC+IVP +F+IRRSLQETEEF RKH P EI S+ +NW++V AG ++VVM Sbjct: 187 WRVPFLVGCLIVPFLFLIRRSLQETEEFKQRKHRPALGEIFRSMGENWRLVGAGTLLVVM 246 Query: 252 TTVSFYLITVYTPTFGKTVLKLSASDSLIVTFCVGLSNFCWLPVMGALSDRVGRRPVLVA 311 TTVSFYLIT YTPTFGK+VL LS DSLIVT CVG SNF WLPVMG++SDR+GRRP+L+ Sbjct: 247 TTVSFYLITAYTPTFGKSVLHLSNLDSLIVTLCVGASNFFWLPVMGSVSDRIGRRPLLIT 306 Query: 312 FTLLTLLTAYPMMSWLVADISFKNLLITELWLSFLYASYNGAAVVALTEVMPAHVRT 368 FT LTLLTAYP M WL+A+ SF LL ELWLSFLY SYNGA VV LTE+MP VRT Sbjct: 307 FTALTLLTAYPAMQWLIAEPSFGRLLAVELWLSFLYGSYNGAMVVTLTEIMPPAVRT 363 >STM0689 [GEPR] COG0477 Permeases of the major facilitator superfamily Sty Salmonella typhimurium LT2 Length = 434 Score = 507 bits (1306), Expect = e-143, Method: Compositional matrix adjust. Identities = 242/363 (66%), Positives = 291/363 (80%) Query: 6 KTSCTAKHSKLSTVLRVTSGNFLEMFDFFLYGFYASYISRTLFPSDNEFVSLILTFGTFG 65 T T++ +LRVTSGNFLE FDFFL+GFYA+YI+RT FP+++EF SL+LTF FG Sbjct: 4 HTPATSRAGTFGAILRVTSGNFLEQFDFFLFGFYATYIARTFFPAESEFASLMLTFAVFG 63 Query: 66 AGFLMRPLGAIILGSYIDRVGRRQGLIVTLAIMAIGTLLIAFVPGYATIGITAPILVLTG 125 +GFLMRP+GAI+LG+YIDR+GRR+GL+VTLAIM GTLLIA VPGY TIG+ AP LVL G Sbjct: 64 SGFLMRPVGAIVLGAYIDRIGRRKGLMVTLAIMGCGTLLIALVPGYQTIGLAAPALVLLG 123 Query: 126 RLLQGFSAGVELGGVSVYLAEMATPGNKGFYVSWQSASQQAAIMASALIGYLVSQWLSPL 185 RLLQGFSAGVELGGVSVYL+E+ATPGNKGFY SWQSASQQ AI+ +ALIGY ++ L Sbjct: 124 RLLQGFSAGVELGGVSVYLSEIATPGNKGFYTSWQSASQQVAIVVAALIGYSLNITLGHD 183 Query: 186 QISEWGWRIPFFIGCMIVPAIFIIRRSLQETEEFMARKHHPGFAEIMASIAQNWKIVVAG 245 ISEWGWRIPFFIGCMI+P IF++RRSLQETE F+ RKH P EI A+IA+NW+I+ AG Sbjct: 184 AISEWGWRIPFFIGCMIIPLIFVLRRSLQETEAFLQRKHRPDTREIFATIAKNWRIITAG 243 Query: 246 MMMVVMTTVSFYLITVYTPTFGKTVLKLSASDSLIVTFCVGLSNFCWLPVMGALSDRVGR 305 ++V MTT +FY ITVYTPT+G+TVL LSA DSLIVT VG+SNF WLP+ GA+SDR+GR Sbjct: 244 TLLVAMTTTTFYFITVYTPTYGRTVLNLSARDSLIVTMLVGVSNFIWLPIGGAISDRIGR 303 Query: 306 RPVLVAFTLLTLLTAYPMMSWLVADISFKNLLITELWLSFLYASYNGAAVVALTEVMPAH 365 R VL+ TLL L+T +P+M WL A F + + LW SF + YNGA V ALTEVMP + Sbjct: 304 RAVLMGITLLALITTWPVMQWLTAAPDFTRMTLVLLWFSFFFGMYNGAMVAALTEVMPVY 363 Query: 366 VRT 368 VRT Sbjct: 364 VRT 366 >PA5476 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 429 Score = 495 bits (1275), Expect = e-140, Method: Compositional matrix adjust. Identities = 248/358 (69%), Positives = 298/358 (83%) Query: 11 AKHSKLSTVLRVTSGNFLEMFDFFLYGFYASYISRTLFPSDNEFVSLILTFGTFGAGFLM 70 + SK + RV SGNFLEM+DF +YGFYA+ I++T FP DN F SL+L+ TFGAGFLM Sbjct: 3 SNKSKGVAIFRVVSGNFLEMYDFMVYGFYATAIAKTFFPGDNPFASLMLSLATFGAGFLM 62 Query: 71 RPLGAIILGSYIDRVGRRQGLIVTLAIMAIGTLLIAFVPGYATIGITAPILVLTGRLLQG 130 RPLGA+ LG+YIDR GRRQGLI+TL +MA+GTLLIAFVPGYAT+G+ AP+LVL GRLLQG Sbjct: 63 RPLGAVFLGAYIDRHGRRQGLIITLGLMAMGTLLIAFVPGYATLGVAAPLLVLFGRLLQG 122 Query: 131 FSAGVELGGVSVYLAEMATPGNKGFYVSWQSASQQAAIMASALIGYLVSQWLSPLQISEW 190 FSAGVELGGVSVYL+E+ATPG KGF+VSWQSASQQ A++ + L+G L++QWLSP + EW Sbjct: 123 FSAGVELGGVSVYLSEIATPGRKGFFVSWQSASQQVAVVFAGLLGVLLNQWLSPQDMGEW 182 Query: 191 GWRIPFFIGCMIVPAIFIIRRSLQETEEFMARKHHPGFAEIMASIAQNWKIVVAGMMMVV 250 GWR+PFFIGC+IVPA+F+IRRSL+ET EF AR H P ++++ SI QN+ +V+AG MVV Sbjct: 183 GWRVPFFIGCLIVPALFVIRRSLEETPEFEARTHRPSLSQVLRSIGQNFGVVLAGTAMVV 242 Query: 251 MTTVSFYLITVYTPTFGKTVLKLSASDSLIVTFCVGLSNFCWLPVMGALSDRVGRRPVLV 310 MTTVSFYLIT YTPTFGK L+LS DSL+VT C+GLSNF WLPVMGA SDR+GR+P+L+ Sbjct: 243 MTTVSFYLITAYTPTFGKNELQLSDLDSLLVTMCIGLSNFIWLPVMGAFSDRIGRKPLLL 302 Query: 311 AFTLLTLLTAYPMMSWLVADISFKNLLITELWLSFLYASYNGAAVVALTEVMPAHVRT 368 + L LLTAYP +SWLV + SF LL ELWLSFLY+SYNGA VVALTEVMPA VRT Sbjct: 303 GASALALLTAYPALSWLVREPSFAGLLGVELWLSFLYSSYNGAMVVALTEVMPADVRT 360 >RSc3060 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 433 Score = 492 bits (1266), Expect = e-139, Method: Compositional matrix adjust. Identities = 235/357 (65%), Positives = 283/357 (79%) Query: 12 KHSKLSTVLRVTSGNFLEMFDFFLYGFYASYISRTLFPSDNEFVSLILTFGTFGAGFLMR 71 SK + RV SGNFLEMFDF +YG+YA+ I+ T FP+ N F+SL+L+ TFGAGFLMR Sbjct: 7 NESKARAIFRVVSGNFLEMFDFMVYGYYATAIAATFFPAGNAFLSLMLSLMTFGAGFLMR 66 Query: 72 PLGAIILGSYIDRVGRRQGLIVTLAIMAIGTLLIAFVPGYATIGITAPILVLTGRLLQGF 131 PLGAI+LG+YIDR GRR GLI+TL +MA GT+LIA VPGY TIG+ AP+LVL GRLLQGF Sbjct: 67 PLGAIVLGAYIDRHGRRAGLILTLVLMACGTMLIALVPGYGTIGLAAPLLVLIGRLLQGF 126 Query: 132 SAGVELGGVSVYLAEMATPGNKGFYVSWQSASQQAAIMASALIGYLVSQWLSPLQISEWG 191 SAG E GGVSVYL+E+ATPG KGFYVSWQS SQQ A+M +AL+G L+S LSP ++ EWG Sbjct: 127 SAGGEPGGVSVYLSEIATPGRKGFYVSWQSGSQQVAVMFAALLGVLLSFKLSPKEMGEWG 186 Query: 192 WRIPFFIGCMIVPAIFIIRRSLQETEEFMARKHHPGFAEIMASIAQNWKIVVAGMMMVVM 251 WR+PF IGC+IVP +F IRRSL+ETEEF RKH P E++ S+ +NW++ AG ++ VM Sbjct: 187 WRVPFLIGCLIVPFLFFIRRSLRETEEFEQRKHRPTMGELLRSMGENWRLAGAGTLLAVM 246 Query: 252 TTVSFYLITVYTPTFGKTVLKLSASDSLIVTFCVGLSNFCWLPVMGALSDRVGRRPVLVA 311 TTVSFYLIT YTPTFG+ VL +S DSLIVT CVG SN WLPVMG+LSDR+GRR L+ Sbjct: 247 TTVSFYLITAYTPTFGRNVLHMSDFDSLIVTLCVGASNLIWLPVMGSLSDRIGRRTPLIV 306 Query: 312 FTLLTLLTAYPMMSWLVADISFKNLLITELWLSFLYASYNGAAVVALTEVMPAHVRT 368 F+ LTLLTAYP M+WL+A+ SF LL ELWLSFLY YNGA +V LTE+MP +RT Sbjct: 307 FSALTLLTAYPAMTWLIAEPSFGRLLAVELWLSFLYGGYNGAMIVTLTEIMPPQLRT 363 >PA4343 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 439 Score = 247 bits (631), Expect = 3e-65, Method: Compositional matrix adjust. Identities = 138/362 (38%), Positives = 201/362 (55%), Gaps = 1/362 (0%) Query: 8 SCTAKHSKLSTVLRVTSGNFLEMFDFFLYGFYASYISRTLFPSDNEFVSLILTFGTFGAG 67 +C + S+ V GN LE +DF +YGF +S I+R FPS +E+ SL++ TFG G Sbjct: 3 ACPSGTSRTRQVAAAVIGNALEWYDFIVYGFLSSLIARLFFPSGDEYTSLLMALATFGVG 62 Query: 68 FLMRPLGAIILGSYIDRVGRRQGLIVTLAIMAIGTLLIAFVPGYATIGITAPILVLTGRL 127 F MRP+G ++LG Y DR GR+ + + + +M + +IAF P YA IG+ AP+L++ R+ Sbjct: 63 FFMRPVGGVLLGLYADRRGRKAAMQLIILLMTLSIAMIAFAPTYAAIGVGAPLLIVIARM 122 Query: 128 LQGFSAGVELGGVSVYLAEMATPGNKGFYVSWQSASQQAAIMASALIGYLVSQWLSPLQI 187 LQGF+ G E + +L E A P +G Y SWQ Q A+ A A +G LV+ L + Sbjct: 123 LQGFATGGEYASATAFLVESAPPHRRGLYGSWQLFGQCLAVFAGAGMGALVTHCLDAEAL 182 Query: 188 SEWGWRIPFFIGCMIVPAIFIIRRSLQETEEFMARKHHPGFAEIMASIAQNW-KIVVAGM 246 WGWR+PF G +I P IRR + ETE F+ PG + + + + + + V+ M Sbjct: 183 ESWGWRVPFLFGLLIGPVGLWIRRYMGETEAFLEAIREPGERQGLLGVLREYRRSVLVSM 242 Query: 247 MMVVMTTVSFYLITVYTPTFGKTVLKLSASDSLIVTFCVGLSNFCWLPVMGALSDRVGRR 306 + V+ TVSFY++ V PTF L L + +V +P+ G LSDRVGRR Sbjct: 243 GLTVVGTVSFYVVLVNMPTFAHKQLGLPLDEVFMVQMAAVALMTLVIPLAGGLSDRVGRR 302 Query: 307 PVLVAFTLLTLLTAYPMMSWLVADISFKNLLITELWLSFLYASYNGAAVVALTEVMPAHV 366 PVL+ TL +L YP+ +W+ A S LL+ +L L + G A A+ E P V Sbjct: 303 PVLLVATLAFMLMVYPLFAWVAAAPSLGRLLLMQLLLCTAIGGFFGPAPTAVAEQFPVRV 362 Query: 367 RT 368 R+ Sbjct: 363 RS 364