BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0031.0096.p (452 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0177 [M] COG1207 N-acetylglucosamine-1-phosphate uridyltransf... 658 0.0 HI0642 [M] COG1207 N-acetylglucosamine-1-phosphate uridyltransfe... 525 e-149 PM1806 [M] COG1207 N-acetylglucosamine-1-phosphate uridyltransfe... 522 e-148 YPO4119 [M] COG1207 N-acetylglucosamine-1-phosphate uridyltransf... 522 e-148 STM3862 [M] COG1207 N-acetylglucosamine-1-phosphate uridyltransf... 516 e-146 >RSc0177 [M] COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Rso Ralstonia solanacearum Length = 455 Score = 658 bits (1698), Expect = 0.0, Method: Compositional matrix adjust. Identities = 329/453 (72%), Positives = 372/453 (82%), Gaps = 1/453 (0%) Query: 1 MNIVILAAGMGKRMQSALPKVLHPLAGKPLLGHVIDTARQLVPTQLCVIYGHGGDAVPKA 60 MNIVILAAG+GKRM+SALPKVLHPLAGKPLL HVI+TAR L PT+L V+ GHGGD V Sbjct: 1 MNIVILAAGLGKRMRSALPKVLHPLAGKPLLAHVIETARSLSPTRLVVVVGHGGDRVRDM 60 Query: 61 FAGQGLSFALQEPQLGTGHAVMQAVPHLDDGAPTLVLYGDVPLTTAASLQRLLDAAGQDK 120 ++FA Q+ QLGTGHAVMQA+ LDD PTLVLYGDVPLT A +L L+ AAGQD Sbjct: 61 VGAPDVTFATQDQQLGTGHAVMQALDQLDDTVPTLVLYGDVPLTRAETLNALVGAAGQDH 120 Query: 121 LGVLTVTLDNPTGYGRIVRE-DGQIKRIVEQKDASEAERAIREVNTGIIVAPTARLRQWL 179 LGVLTV LD+PTGYGRIVR+ G+I RIVEQKDA+E + AI EVNTGI+V PTARL+ WL Sbjct: 121 LGVLTVHLDDPTGYGRIVRDATGRITRIVEQKDANETQLAIHEVNTGILVCPTARLKTWL 180 Query: 180 AKLSNNNAQGEYYLTDVIAAAVADGVEVVSAQPDDVAETLGVNSKVQLAELERVHQRNIA 239 A L N+NAQGEYYLTDVI A ++G+ + SA P ETLGVNSKVQLAELER+HQRN+A Sbjct: 181 ATLRNDNAQGEYYLTDVIERAASEGLPITSAHPLAEWETLGVNSKVQLAELERIHQRNLA 240 Query: 240 HGLLEKGVTLADPARIDVRGALECGRDVSIDVNCVFEGQVSIGEGSSIGAHCVIRNARIG 299 LLE GVTL DPARID+RG L CGRDV ID++C+FEG V++G+G IGAH VIR+A I Sbjct: 241 QQLLEDGVTLIDPARIDIRGRLTCGRDVVIDIDCIFEGNVTLGDGVRIGAHAVIRDAAIQ 300 Query: 300 AGVAIKPFTHIEDAVVGAGGQIGPYARLRPGTELAQDVHIGNFVEVKNSNVGVGSKANHL 359 AG I PF HIE A VGA +IGPYARLRPGTELA+DVHIGNFVEVKNS + SKANHL Sbjct: 301 AGAEILPFCHIEQATVGAQSRIGPYARLRPGTELAEDVHIGNFVEVKNSQIAAHSKANHL 360 Query: 360 AYVGDADVGSGVNVGAGVITCNYDGANKFRTIIEDGAFIGSDTQLVAPVRVGKGATIGAG 419 AYVGDA VGS VN+GAG ITCNYDGANKFRTIIED AFIGSDTQLVAPVRVG+GAT+GAG Sbjct: 361 AYVGDATVGSRVNIGAGTITCNYDGANKFRTIIEDDAFIGSDTQLVAPVRVGRGATLGAG 420 Query: 420 TTLTKDAPADQLTLSRAKQLSLAGWQRPVKIKK 452 TTLTKDAP QLT+SRA+Q ++ GWQRPVK KK Sbjct: 421 TTLTKDAPEGQLTVSRARQTTVNGWQRPVKQKK 453 >HI0642 [M] COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Hin Haemophilus influenzae Length = 456 Score = 525 bits (1352), Expect = e-149, Method: Compositional matrix adjust. Identities = 251/451 (55%), Positives = 326/451 (72%) Query: 1 MNIVILAAGMGKRMQSALPKVLHPLAGKPLLGHVIDTARQLVPTQLCVIYGHGGDAVPKA 60 ++ VILAAG G RM S LPKVLH +AGKP++ HVIDTA QL + +IYGHGGD + Sbjct: 6 LSAVILAAGKGTRMYSDLPKVLHTIAGKPMVKHVIDTAHQLGSENIHLIYGHGGDLMRTH 65 Query: 61 FAGQGLSFALQEPQLGTGHAVMQAVPHLDDGAPTLVLYGDVPLTTAASLQRLLDAAGQDK 120 A + +++ LQ QLGT HAV QA P D +VLYGD PL T +L++L++A ++ Sbjct: 66 LANEQVNWVLQTEQLGTAHAVQQAAPFFKDNENIVVLYGDAPLITKETLEKLIEAKPENG 125 Query: 121 LGVLTVTLDNPTGYGRIVREDGQIKRIVEQKDASEAERAIREVNTGIIVAPTARLRQWLA 180 + +LTV LDNPTGYGRI+RE+G + IVEQKDA+ + I+EVNTG++V+ A ++WLA Sbjct: 126 IALLTVNLDNPTGYGRIIRENGNVVAIVEQKDANAEQLNIKEVNTGVMVSDGASFKKWLA 185 Query: 181 KLSNNNAQGEYYLTDVIAAAVADGVEVVSAQPDDVAETLGVNSKVQLAELERVHQRNIAH 240 ++ NNNAQGEYYLTD+IA A D +VV+ Q DV E G N+++QLA LER Q A Sbjct: 186 RVGNNNAQGEYYLTDLIALANQDNCQVVAVQATDVMEVEGANNRLQLAALERYFQNKQAS 245 Query: 241 GLLEKGVTLADPARIDVRGALECGRDVSIDVNCVFEGQVSIGEGSSIGAHCVIRNARIGA 300 LL +GV + DPAR D+RG LE G+DV IDVN + EG V +G+ IG CV++N IG Sbjct: 246 KLLLEGVMIYDPARFDLRGTLEHGKDVEIDVNVIIEGNVKLGDRVKIGTGCVLKNVVIGN 305 Query: 301 GVAIKPFTHIEDAVVGAGGQIGPYARLRPGTELAQDVHIGNFVEVKNSNVGVGSKANHLA 360 V IKP++ +ED++VG IGP++RLRPG ELA + H+GNFVE+K S VG GSK NHL Sbjct: 306 DVEIKPYSVLEDSIVGEKAAIGPFSRLRPGAELAAETHVGNFVEIKKSTVGKGSKVNHLT 365 Query: 361 YVGDADVGSGVNVGAGVITCNYDGANKFRTIIEDGAFIGSDTQLVAPVRVGKGATIGAGT 420 YVGD+++GS N+GAGVITCNYDGANKF+TII D F+GSDTQLVAPV+V GATIGAGT Sbjct: 366 YVGDSEIGSNCNIGAGVITCNYDGANKFKTIIGDDVFVGSDTQLVAPVKVANGATIGAGT 425 Query: 421 TLTKDAPADQLTLSRAKQLSLAGWQRPVKIK 451 T+T+D ++L ++R Q + GWQRP+K K Sbjct: 426 TITRDVGENELVITRVAQRHIQGWQRPIKKK 456 >PM1806 [M] COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Pmu Pasteurella multocida Length = 458 Score = 522 bits (1344), Expect = e-148, Method: Compositional matrix adjust. Identities = 254/452 (56%), Positives = 327/452 (72%) Query: 1 MNIVILAAGMGKRMQSALPKVLHPLAGKPLLGHVIDTARQLVPTQLCVIYGHGGDAVPKA 60 ++IVILAAG G RM S LPKVLH +AGKP++ HVIDT + + + ++YGHGG+ + Sbjct: 6 LSIVILAAGKGTRMYSDLPKVLHKIAGKPMVKHVIDTVKSIHAKNIHLVYGHGGEVMQTR 65 Query: 61 FAGQGLSFALQEPQLGTGHAVMQAVPHLDDGAPTLVLYGDVPLTTAASLQRLLDAAGQDK 120 + +++ LQ QLGTGHA+ QA P D L+LYGD PL TA +LQ L+ A + Sbjct: 66 LQDEPVNWVLQAEQLGTGHAMQQAAPFFADDENILMLYGDGPLITAETLQTLIAAKPEHG 125 Query: 121 LGVLTVTLDNPTGYGRIVREDGQIKRIVEQKDASEAERAIREVNTGIIVAPTARLRQWLA 180 + +LTV LD+PTGYGRIVRE+G + IVEQKDA+ + I+E+NTG++VA L++WL+ Sbjct: 126 IALLTVVLDDPTGYGRIVRENGNVVAIVEQKDANAEQLKIQEINTGLLVADGKSLKKWLS 185 Query: 181 KLSNNNAQGEYYLTDVIAAAVADGVEVVSAQPDDVAETLGVNSKVQLAELERVHQRNIAH 240 +L+NNNAQGEYY+TDVIA A DG +VV+ Q D E GVN++ QLA LER +QR A Sbjct: 186 QLTNNNAQGEYYITDVIALANQDGCQVVAVQASDFMEVEGVNNRQQLARLERYYQRKQAD 245 Query: 241 GLLEKGVTLADPARIDVRGALECGRDVSIDVNCVFEGQVSIGEGSSIGAHCVIRNARIGA 300 LL GV LADP R D+RG L G+DV IDVN + EG+VS+G IGA CV++N +IG Sbjct: 246 NLLLAGVALADPERFDLRGELSHGKDVEIDVNVIIEGKVSLGHRVKIGAGCVLKNCQIGD 305 Query: 301 GVAIKPFTHIEDAVVGAGGQIGPYARLRPGTELAQDVHIGNFVEVKNSNVGVGSKANHLA 360 V IKP++ +E+A+VG QIGP++RLRPGT LA + HIGNFVE+K +++G GSK NHL+ Sbjct: 306 DVEIKPYSVLEEAIVGQAAQIGPFSRLRPGTALADNTHIGNFVEIKKAHIGTGSKVNHLS 365 Query: 361 YVGDADVGSGVNVGAGVITCNYDGANKFRTIIEDGAFIGSDTQLVAPVRVGKGATIGAGT 420 YVGDA+VG N+GAGVITCNYDGANKF+TII D F+GSD QLVAPV + GATIGAGT Sbjct: 366 YVGDAEVGMQCNIGAGVITCNYDGANKFKTIIGDNVFVGSDVQLVAPVTIETGATIGAGT 425 Query: 421 TLTKDAPADQLTLSRAKQLSLAGWQRPVKIKK 452 T+TKD D+L +SR Q + GWQRP K K Sbjct: 426 TVTKDVACDELVISRVPQRHIQGWQRPTKQTK 457 >YPO4119 [M] COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Ype Yersinia pestis Length = 456 Score = 522 bits (1344), Expect = e-148, Method: Compositional matrix adjust. Identities = 254/451 (56%), Positives = 330/451 (73%) Query: 1 MNIVILAAGMGKRMQSALPKVLHPLAGKPLLGHVIDTARQLVPTQLCVIYGHGGDAVPKA 60 M++VILAAG G RM S LPKVLHPLAGKP++ HVID A +L + ++YGHGG+ + K Sbjct: 6 MSVVILAAGKGTRMYSDLPKVLHPLAGKPMVQHVIDAAMKLGAQHVHLVYGHGGELLKKT 65 Query: 61 FAGQGLSFALQEPQLGTGHAVMQAVPHLDDGAPTLVLYGDVPLTTAASLQRLLDAAGQDK 120 A L++ LQ QLGTGHA+ QA PH D L+LYGDVPL + +LQRLL A + Sbjct: 66 LADPSLNWVLQAEQLGTGHAMQQAAPHFADDEDILMLYGDVPLISVDTLQRLLAAKPEGG 125 Query: 121 LGVLTVTLDNPTGYGRIVREDGQIKRIVEQKDASEAERAIREVNTGIIVAPTARLRQWLA 180 +G+LTV LDNP+GYGRIVRE+G + IVE KDAS+A+R I E+NTGI+VA L++WL+ Sbjct: 126 IGLLTVKLDNPSGYGRIVRENGDVVGIVEHKDASDAQREINEINTGILVANGRDLKRWLS 185 Query: 181 KLSNNNAQGEYYLTDVIAAAVADGVEVVSAQPDDVAETLGVNSKVQLAELERVHQRNIAH 240 L NNNAQGE+Y+TD+IA A ADG ++ + P ++E GVN+++QL+ LERV Q A Sbjct: 186 LLDNNNAQGEFYITDIIALAHADGKKIATVHPTRLSEVEGVNNRLQLSALERVFQTEQAE 245 Query: 241 GLLEKGVTLADPARIDVRGALECGRDVSIDVNCVFEGQVSIGEGSSIGAHCVIRNARIGA 300 LL GV L DP+R D+RG L GRD++ID N + EG V +G+ IG CV++N IG Sbjct: 246 KLLLAGVMLLDPSRFDLRGELTHGRDITIDTNVIIEGHVILGDRVRIGTGCVLKNCVIGD 305 Query: 301 GVAIKPFTHIEDAVVGAGGQIGPYARLRPGTELAQDVHIGNFVEVKNSNVGVGSKANHLA 360 I P+T +EDA + A +GP+ARLRPG ELA+ H+GNFVE+K + +G GSKA HL+ Sbjct: 306 DSEISPYTVLEDARLDANCTVGPFARLRPGAELAEGAHVGNFVEIKKARLGKGSKAGHLS 365 Query: 361 YVGDADVGSGVNVGAGVITCNYDGANKFRTIIEDGAFIGSDTQLVAPVRVGKGATIGAGT 420 Y+GDA++G+GVN+GAG ITCNYDGANKF+TII D F+GSDTQLVAPV V GATIGAGT Sbjct: 366 YLGDAEIGAGVNIGAGTITCNYDGANKFKTIIGDDVFVGSDTQLVAPVTVANGATIGAGT 425 Query: 421 TLTKDAPADQLTLSRAKQLSLAGWQRPVKIK 451 T+T+D ++L +SR KQ+ + GW+RPVK K Sbjct: 426 TVTRDVAENELVISRVKQVHIQGWKRPVKKK 456 >STM3862 [M] COG1207 N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Sty Salmonella typhimurium LT2 Length = 456 Score = 516 bits (1330), Expect = e-146, Method: Compositional matrix adjust. Identities = 248/451 (54%), Positives = 327/451 (72%) Query: 1 MNIVILAAGMGKRMQSALPKVLHPLAGKPLLGHVIDTARQLVPTQLCVIYGHGGDAVPKA 60 M++VILAAG G RM S +PKVLH LAGKP++ HVID A +L Q+ ++YGHGG+ + + Sbjct: 6 MSVVILAAGKGTRMYSDIPKVLHTLAGKPMVQHVIDAATKLGAAQVHLVYGHGGELLKQT 65 Query: 61 FAGQGLSFALQEPQLGTGHAVMQAVPHLDDGAPTLVLYGDVPLTTAASLQRLLDAAGQDK 120 L++ LQ QLGTGHA+ QA P D L+LYGDVPL + +LQRL DA Q Sbjct: 66 LKDDKLNWVLQAEQLGTGHAMQQAAPFFSDDEDILMLYGDVPLISVETLQRLRDAKPQGG 125 Query: 121 LGVLTVTLDNPTGYGRIVREDGQIKRIVEQKDASEAERAIREVNTGIIVAPTARLRQWLA 180 +G+LTV LD+P+GYGRI RE+G++ IVE KDA++ +R I+E+NTGI++A A +++WL+ Sbjct: 126 IGLLTVKLDDPSGYGRITRENGKVTGIVEHKDATDEQRQIQEINTGILIANGADMKRWLS 185 Query: 181 KLSNNNAQGEYYLTDVIAAAVADGVEVVSAQPDDVAETLGVNSKVQLAELERVHQRNIAH 240 KL+NNNAQGEYY+TD+IA A +G E+ + P ++ET GVN+++QL+ LER++Q A Sbjct: 186 KLTNNNAQGEYYITDIIALAYQEGREIAAVHPARISETDGVNNRLQLSRLERIYQAEQAE 245 Query: 241 GLLEKGVTLADPARIDVRGALECGRDVSIDVNCVFEGQVSIGEGSSIGAHCVIRNARIGA 300 LL GV L DPAR D+RG L CG DV ID N + EG V++G IGA C+I+N+ IG Sbjct: 246 KLLLSGVMLRDPARFDLRGTLHCGMDVEIDANVIIEGYVTLGHRVKIGAGCIIKNSVIGD 305 Query: 301 GVAIKPFTHIEDAVVGAGGQIGPYARLRPGTELAQDVHIGNFVEVKNSNVGVGSKANHLA 360 I P++ +EDA + A IGP+ARLRPG EL H+GNFVE+K + +G GSKA HL Sbjct: 306 DCEISPYSVVEDAHLEAACTIGPFARLRPGAELLAGAHVGNFVEMKKARLGKGSKAGHLT 365 Query: 361 YVGDADVGSGVNVGAGVITCNYDGANKFRTIIEDGAFIGSDTQLVAPVRVGKGATIGAGT 420 Y+GDA++G VN+GAG ITCNYDGANKF+T+I D F+GSDTQLVAPV VGKGATI AGT Sbjct: 366 YLGDAEIGDNVNIGAGTITCNYDGANKFKTVIGDDVFVGSDTQLVAPVTVGKGATIAAGT 425 Query: 421 TLTKDAPADQLTLSRAKQLSLAGWQRPVKIK 451 T+T++ ++L LSR Q+ GWQRPVK K Sbjct: 426 TVTRNVADNELVLSRVPQVHKQGWQRPVKKK 456