BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0031.0049.p (275 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value TM0954 [G] COG3959 Transketolase, N-terminal subunit Tma Thermot... 246 5e-65 FN0294 [G] COG3959 Transketolase, N-terminal subunit Fnu Fusobac... 221 1e-57 TVN0668 [G] COG3959 Transketolase, N-terminal subunit Tvo Thermo... 210 3e-54 AGc3490 [G] COG3959 Transketolase, N-terminal subunit Atu Agroba... 206 3e-53 MJ0681 [G] COG3959 Transketolase, N-terminal subunit Mja Methano... 205 8e-53 >TM0954 [G] COG3959 Transketolase, N-terminal subunit Tma Thermotoga maritima Length = 286 Score = 246 bits (627), Expect = 5e-65, Method: Compositional matrix adjust. Identities = 119/272 (43%), Positives = 172/272 (63%), Gaps = 2/272 (0%) Query: 3 QDITALKKTASQLRGRIIENAHRTQTPHLGSCLSCVDILTAAYFGTLRIDPSRPADPLRD 62 ++ LK+ A ++R I++ ++ ++ H G LS V+IL ++ LR+ P P RD Sbjct: 7 HEVLELKRKAIEIRKMILDMIYKAKSGHTGGSLSSVEILVTLFYKILRVKPEDPNWEDRD 66 Query: 63 RFILSKGHGAAALFQVLALRGFYPIAMLDDYGKDGGIFAEHPPTPDHLPGIEAATGSLGH 122 RFILSKGH A + VLA +GF+P L+ Y K G HP +PG+E TG+LGH Sbjct: 67 RFILSKGHSVEAYYAVLADKGFFPKEELETYCKYGSRLTGHPTRK--VPGVEVNTGALGH 124 Query: 123 GLPIGLGMALAGRIQQQRYDVTVLLGDGECNEGSVWEAAMMAAAQRTGNLMVLVDFNKWQ 182 GL IG+GMALAG++ + Y V VL+GDGE +EGSVWEAA +A+ NL+ +VD N+ Q Sbjct: 125 GLAIGVGMALAGKMDGKDYKVYVLMGDGELDEGSVWEAAQVASHYSLDNLIGIVDRNRLQ 184 Query: 183 ATGRSEEVLALNPLVDKWRAFGWDAMEIDGHDMATLVEIMGRPRAPEGKPIAVVAHTVKG 242 +G +EEVL L PL +W AFGW+ +E+DGHD +L + GKP ++A+T+KG Sbjct: 185 ISGHTEEVLKLEPLSKRWEAFGWNVLEVDGHDFESLYKTFVSIPRETGKPHLIIANTIKG 244 Query: 243 KGVSFMEDDNNWHYRIPNADEVAAAYQELGVQ 274 KG+SF+E WH+++P+ +E A +EL Q Sbjct: 245 KGISFIEGRVEWHHKVPSDEEYRKAIEELEEQ 276 >FN0294 [G] COG3959 Transketolase, N-terminal subunit Fnu Fusobacterium nucleatum Length = 270 Score = 221 bits (564), Expect = 1e-57, Method: Compositional matrix adjust. Identities = 113/269 (42%), Positives = 155/269 (57%), Gaps = 1/269 (0%) Query: 3 QDITALKKTASQLRGRIIENAHRTQTPHLGSCLSCVDILTAAYFGTLRIDPSRPADPLRD 62 +DI+ LK+ A ++R I+ ++ H G LS DILTA YF + +DP+ P RD Sbjct: 2 KDISFLKEKAKEIRKSIVSMIAEAKSGHPGGSLSATDILTALYFSEMNVDPTNPKMEGRD 61 Query: 63 RFILSKGHGAAALFQVLALRGFYPIAMLDDYGKDGGIFAEHPPTPDHLPGIEAATGSLGH 122 RF+LSKGH A A++ LA +G++ L K G HP L GIE +TGSLG Sbjct: 62 RFVLSKGHAAPAIYATLAEKGYFSKDELMTLRKFGSRLQGHPDMK-KLSGIEISTGSLGQ 120 Query: 123 GLPIGLGMALAGRIQQQRYDVTVLLGDGECNEGSVWEAAMMAAAQRTGNLMVLVDFNKWQ 182 GL + GMAL +I + Y V+LGDGE EG +WEAAM AA + NL +D N Q Sbjct: 121 GLSVANGMALNAKIFDENYRTYVVLGDGEIQEGQIWEAAMTAAHYKLDNLCAFLDSNNLQ 180 Query: 183 ATGRSEEVLALNPLVDKWRAFGWDAMEIDGHDMATLVEIMGRPRAPEGKPIAVVAHTVKG 242 G E+ + PL KW AFGW+ ++IDGHD ++ + + R +GKP ++A T+KG Sbjct: 181 IDGNVTEIKGVEPLDKKWEAFGWNVIKIDGHDFEQILSALEKARECKGKPTMIIAKTIKG 240 Query: 243 KGVSFMEDDNNWHYRIPNADEVAAAYQEL 271 KGVSFME+ +H P +E+ A EL Sbjct: 241 KGVSFMENVCGFHGVAPTVEELERALAEL 269 >TVN0668 [G] COG3959 Transketolase, N-terminal subunit Tvo Thermoplasma volcanium Length = 273 Score = 210 bits (534), Expect = 3e-54, Method: Compositional matrix adjust. Identities = 108/268 (40%), Positives = 161/268 (60%), Gaps = 4/268 (1%) Query: 8 LKKTASQLRGRIIENAHRTQTPHLGSCLSCVDILTAAYFGTLRIDPSRPADPLRDRFILS 67 L A ++R II + Q+ H G LS DILT YF + IDP++P DP RDR ILS Sbjct: 8 LSDIALKIRREIIRMVYNAQSGHPGGSLSVTDILTVLYFKEMNIDPNKPKDPKRDRLILS 67 Query: 68 KGHGAAALFQVLALRGFYPIAMLDDYGKDGGIFAEHPPTPDHLPGIEAATGSLGHGLPIG 127 KGH + AL+ LA+RGF+P++ L + K H +PG+E +TGSLG GL IG Sbjct: 68 KGHASPALYATLAIRGFFPVSDLSGFRKLDSHLEGH--VTREVPGVEVSTGSLGQGLGIG 125 Query: 128 LGMALAGRIQQQRYDVTVLLGDGECNEGSVWEAAMMAAAQRTGNLMVLVDFNKWQATGRS 187 +GMALAGR+ +Y V V+LGDGE EG+VWE+ M N+ ++D N Q G + Sbjct: 126 VGMALAGRLDGMQYRVYVILGDGEMEEGNVWESLMAGYKYNLNNITAILDKNGIQLDGYT 185 Query: 188 EEVLALNPLVDKWRAFGWDAMEIDGHDMATLVEIMGRPRAPEGKPIAVVAHTVKGKGVSF 247 ++++ ++ + +FGW+ +EIDGH+ + E + + + +P ++A+TVKGKGV F Sbjct: 186 KDIMPMHDIKSMVESFGWNVIEIDGHNYDQIHEAVQASKNSD-RPTFIIANTVKGKGVDF 244 Query: 248 MEDDNNWHYRIPNADEV-AAAYQELGVQ 274 ME++ +H P + E+ A ++LG Q Sbjct: 245 MENNPKYHGSPPESKELFERAMKQLGEQ 272 >AGc3490 [G] COG3959 Transketolase, N-terminal subunit Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 269 Score = 206 bits (525), Expect = 3e-53, Method: Compositional matrix adjust. Identities = 106/264 (40%), Positives = 156/264 (59%), Gaps = 4/264 (1%) Query: 8 LKKTASQLRGRIIENAHRTQTPHLGSCLSCVDILTAAYFGTLRIDPSRPADPLRDRFILS 67 L++ A Q+R R ++ H+G +S +DI+TA YF LRI P+ P +P RDRF+LS Sbjct: 6 LERIARQIRLRDVQAVFEAGAGHVGGEMSAIDIMTALYFRVLRIWPNDPKNPARDRFVLS 65 Query: 68 KGHGAAALFQVLALRGFYPIAMLDDYGKDGGIFAEHPPTPDHLPGIEAATGSLGHGLPIG 127 KGH A AL+ LA RGF P + + + HP + +PG+E TG LGHGLP+ Sbjct: 66 KGHTACALYVTLAKRGFIPEEEISTFLQPNSRLNGHPNC-NKVPGVETNTGPLGHGLPVA 124 Query: 128 LGMALAGRIQQQRYDVTVLLGDGECNEGSVWEAAMMAAAQRTGNLMVLVDFNKWQATGRS 187 +GMA A ++ + Y V+ GDGE EGS WEA M AA + NL +++D N++Q Sbjct: 125 VGMATAAKLSGEDYHTYVMTGDGEMQEGSNWEAIMSAAQFKLNNLTLVIDHNRFQQGAAI 184 Query: 188 EEVLALNPLVDKWRAFGWDAMEIDGHDMATLVEIMGRPRAPEGKPIAVVAHTVKGKGVSF 247 + + PL K AFGW+ EI+G+ MA +V + +P +VAHT KG G+SF Sbjct: 185 ADTNDVAPLRPKLEAFGWEVTEINGNAMAEVVPAL---EHRGNRPHCIVAHTNKGHGISF 241 Query: 248 MEDDNNWHYRIPNADEVAAAYQEL 271 M+D +WH+++P+ ++ A +EL Sbjct: 242 MQDRVDWHHKVPSKEQYEIAVKEL 265 >MJ0681 [G] COG3959 Transketolase, N-terminal subunit Mja Methanococcus jannaschii Length = 274 Score = 205 bits (522), Expect = 8e-53, Method: Compositional matrix adjust. Identities = 111/269 (41%), Positives = 156/269 (57%), Gaps = 3/269 (1%) Query: 4 DITALKKTASQLRGRIIENAHRTQTPHLGSCLSCVDILTAAYFGTLRIDPSRPADPLRDR 63 +I L+K A ++R I++ ++ H G LS DI+ A YF + P P RDR Sbjct: 6 EIKDLEKIAKKVRYNIVKMVGLAKSGHPGGSLSATDIIVALYFKLMNYSPDNPYKKDRDR 65 Query: 64 FILSKGHGAAALFQVLALRGFYPIAMLDDYGKDGGIFAEHPPTPDHLPGIEAATGSLGHG 123 F+LSKGH A AL+ VL+ G L + G HP PG+E TGSLG G Sbjct: 66 FVLSKGHAAPALYAVLSELGIIEEEELWKLRRLEGKLQGHPSMD--TPGVEICTGSLGQG 123 Query: 124 LPIGLGMALAGRIQQQRYDVTVLLGDGECNEGSVWEAAMMAAAQRTGNLMVLVDFNKWQA 183 +GMAL R+ + V VLLGDGEC EG VWEAAM AA + NL+ +D NK Q Sbjct: 124 FSAAVGMALGCRLDKLNNYVYVLLGDGECQEGIVWEAAMAAAHYKLDNLIAFIDRNKLQI 183 Query: 184 TGRSEEVLALNPLVDKWRAFGWDAMEIDGHDMATLVEIMGRPRA-PEGKPIAVVAHTVKG 242 G +E+V++L + K+ AFGWD EIDGH+ ++ + + ++ GKP ++A+TVKG Sbjct: 184 DGCTEDVMSLGDIKAKFEAFGWDVFEIDGHNFEEIINTVEKAKSMKNGKPKMIIAYTVKG 243 Query: 243 KGVSFMEDDNNWHYRIPNADEVAAAYQEL 271 KGVSFME++ +H + PN +++ A +EL Sbjct: 244 KGVSFMENNVAFHGKAPNEEQLKQALEEL 272