BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0031.0005.p (395 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mll1685 [GEPR] COG0477 Permeases of the major facilitator superf... 380 e-105 mlr2429 [GEPR] COG0477 Permeases of the major facilitator superf... 125 1e-28 SMb20272 [GEPR] COG0477 Permeases of the major facilitator super... 119 1e-26 AF0367 [GEPR] COG0477 Permeases of the major facilitator superfa... 93 9e-19 BH2694 [GEPR] COG0477 Permeases of the major facilitator superfa... 89 2e-17 >mll1685 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 469 Score = 380 bits (977), Expect = e-105, Method: Compositional matrix adjust. Identities = 214/388 (55%), Positives = 268/388 (69%), Gaps = 5/388 (1%) Query: 1 MRLCITMILMVVGASGMYVIAVVLPYVQAHYYVDRGLASMPYTLTMLGVGVGGLLMGRMA 60 MRL I+M+L +GA GM+ + VVLP VQ + VDR ASMPYT TM+G G +L+GR Sbjct: 80 MRLAISMVLATIGAVGMWAVVVVLPAVQGEFGVDRAAASMPYTATMVGFAAGNVLVGRAI 139 Query: 61 DRSGITRPMMLGGLCLGGGFLAASWAXAQDIWTFMAVHCILIGLLGTSATFSPLVADTSL 120 DR G P ++ + L G L A A + I F +LIG+ GTS F PL+AD S Sbjct: 140 DRMGYWIPALISSVALSAGLLLA--ALSTSILQFTLAQGVLIGV-GTSVIFGPLIADISH 196 Query: 121 WFRKRRGIAVAVCASGNYLGGAIWPPIVQHFVDNYGWQETYRGLGLICILVMCPLALLMR 180 WF +RRG+AV A+GNYL GA+WP I+ + GW+ TY +G+ C++ M PL L++R Sbjct: 197 WFNRRRGVAVTAAAAGNYLAGALWPTIMPTLIKAEGWRFTYAAIGIFCLVTMVPLVLMLR 256 Query: 181 ARPPVQDSNAATPRAGGGPRPFGLAPGSAQLLLCVVGVACCVAMAMPQVHIVAYCGDLGY 240 P ++ A +P ++P + Q LL V G+ CCVAM+MPQVHIVAYC DLGY Sbjct: 257 RGAP--EATADGSPGSRSVQPIPMSPAAMQGLLVVAGLGCCVAMSMPQVHIVAYCMDLGY 314 Query: 241 GPARGAQMLSLMLACGVVSRLVSGAICDRIGGLRTLLLGSALQGLSLLLFIPFDSLASLY 300 G A GA MLS+M+A GVVSRL SG + DRIGG++TLL+GS LQ LSLL +IPFD LASLY Sbjct: 315 GMAHGADMLSIMMAAGVVSRLASGFVADRIGGVKTLLIGSVLQCLSLLFYIPFDGLASLY 374 Query: 301 LISALFGLFQGGIVPSYAIIVREYFPAAEAGQRVGAVIMATMFGMALGGWMSGKIFDLTG 360 ++S +FGL QGGIVP YAIIVREY PA EAGQR+G V+MAT+FGMA+GGWMSG I+DLTG Sbjct: 375 VVSLVFGLSQGGIVPCYAIIVREYLPAKEAGQRIGIVMMATIFGMAIGGWMSGWIYDLTG 434 Query: 361 SYHAAFANGIAWNLLNLGIAVLLFTRVR 388 SY AF NGIAWNLLN+G L + R Sbjct: 435 SYAVAFLNGIAWNLLNIGAIGLFMWKAR 462 >mlr2429 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 400 Score = 125 bits (315), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 109/367 (29%), Positives = 176/367 (47%), Gaps = 5/367 (1%) Query: 17 MYVIAVVLPYVQAHYYVDRGLASMPYTLTMLGVGVGGLLMGRMADRSGITRPMMLGGLCL 76 M+ +A+ L + R S TL L +G+GG G ++DR G + +G + L Sbjct: 24 MFSLAIFLEPMALDTQWSRAGISSAMTLNFLVMGLGGFAWGALSDRFGARIVVAIGAVLL 83 Query: 77 GGGFLAASWAXAQDIWTFMAVHCILIGLLGTSATFSPLVADTSLWFRKRRGIAVAVCASG 136 G + AS A + TF + +L+GL SA F+P++A T+ WF R +AV++ ++G Sbjct: 84 GLALVVAS--RAGSLLTFQISYGVLVGL-AASAFFAPMIALTTAWFDTNRSLAVSLVSAG 140 Query: 137 NYLGGAIWPPIVQHFVDNYGWQETYRGLGLICILVMCPLALLMRARP-PVQDSNAATPRA 195 + P + + Y W+ +G++ +++ P LL+R P P + A+ P A Sbjct: 141 MGVAPMTISPFARWLISAYEWRTAMFDIGIMAWVLLLPAVLLVRQPPKPAVAAGASAPVA 200 Query: 196 GGGPRPFGLAPGSAQ-LLLCVVGVACCVAMAMPQVHIVAYCGDLGYGPARGAQMLSLMLA 254 G A S Q ++L + CC A + P H+V+Y G P + S+ Sbjct: 201 EGAGMSVAQALRSPQFIVLGLTFFTCCAAHSGPIFHMVSYAMLCGVAPMAAVTIYSVEGL 260 Query: 255 CGVVSRLVSGAICDRIGGLRTLLLGSALQGLSLLLFIPFDSLASLYLISALFGLFQGGIV 314 G+ RL+ G + DR+G L+ G +Q + + ++ L Y+++ +FG GG++ Sbjct: 261 AGLGGRLLYGVLADRLGVKPVLITGLVIQAVVIAAYLSVSQLDQFYVLAVIFGATYGGVM 320 Query: 315 PSYAIIVREYFPAAEAGQRVGAVIMATMFGMALGGWMSGKIFDLTGSYHAAFANGIAWNL 374 P YA++ REYF G GA M + GMALG G +FD SYH F L Sbjct: 321 PLYAVLAREYFGQRILGTVFGAATMLSSLGMALGPLAGGMVFDAYASYHWLFIGSALIGL 380 Query: 375 LNLGIAV 381 GIA+ Sbjct: 381 GAAGIAI 387 >SMb20272 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 402 Score = 119 bits (298), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 78/256 (30%), Positives = 123/256 (48%), Gaps = 1/256 (0%) Query: 108 SATFSPLVADTSLWFRKRRGIAVAVCASGNYLGGAIWPPIVQHFVDNYGWQETYRGLGLI 167 +A F+P++A + WF R +AV++ ++G + P+ V Y W+ + + + + Sbjct: 113 AAIFAPMMACVTGWFDTHRSLAVSLVSAGMGMAPMTMSPLAGWLVTIYDWRTSLQIIAAL 172 Query: 168 CILVMCPLALLMRARPPVQDSNAATPRAGGGPRPFGLAPGSAQ-LLLCVVGVACCVAMAM 226 + M P ALL+R P ++D+NA + G G A S Q ++L + CC + Sbjct: 173 AAVTMIPAALLLRRPPVLEDTNAVSASEGQPDMSLGQALRSPQFVILLLTNFFCCATHSG 232 Query: 227 PQVHIVAYCGDLGYGPARGAQMLSLMLACGVVSRLVSGAICDRIGGLRTLLLGSALQGLS 286 P H V+Y G + SL G+ R+ G + DR G R L+ G LQ Sbjct: 233 PIFHTVSYAVSCGIPMMAAVSIYSLEGLAGMGGRVAFGVLGDRYGAKRILVSGLLLQAFG 292 Query: 287 LLLFIPFDSLASLYLISALFGLFQGGIVPSYAIIVREYFPAAEAGQRVGAVIMATMFGMA 346 L + L + Y ++A+FG G++P YA+I RE FP G +G MA GMA Sbjct: 293 ALAYFFVRDLGAFYAVAAVFGFIYAGVMPLYAVIARENFPLRMMGTVIGGTAMAGSLGMA 352 Query: 347 LGGWMSGKIFDLTGSY 362 +G G I+D+ SY Sbjct: 353 IGPVAGGLIYDVFASY 368 >AF0367 [GEPR] COG0477 Permeases of the major facilitator superfamily Afu Archaeoglobus fulgidus Length = 397 Score = 93.2 bits (230), Expect = 9e-19, Method: Compositional matrix adjust. Identities = 90/341 (26%), Positives = 156/341 (45%), Gaps = 9/341 (2%) Query: 34 DRGLASMPYTLTMLGVGVGGLLMGRMADRSGITRPMMLGGLCLGGGFLAASWAXA-QDIW 92 + +AS+P+++ +L + + GR DR G + MLGG+ LG GFL + + Q + Sbjct: 38 SKTIASLPFSIFLLIFALMMVPAGRTQDRIGPRKVAMLGGVLLGVGFLLSGLIESIQSPY 97 Query: 93 TFMAVHCILIGLLGTSATFSPLVADTSLWFRKRRGIAVAVCASGNYLGGAIWPPIVQHFV 152 + + ++ G G ++ + WF +R G+A + G + I+ P+ + + Sbjct: 98 WLIFSYGVIAGA-GCGLGYACPIPVARKWFPERVGLATGLVVMGFGMSALIFAPLERILI 156 Query: 153 DNYGWQETYRGLGLICILVMCPLALLMRARPP---VQDSNAATPRAGGGPRPFGLAPGSA 209 D YG T+ LG+I ++V A L+ P VQ SN A G G + Sbjct: 157 DTYGISTTFYILGVILLIVAVFAASLLSNPPELPAVQASNPAKVEVVTGKPELGPSEMLR 216 Query: 210 QLLLCVVGVA---CCVAMAMPQVHIVAYCGDLGYGPARGAQMLSLMLACGVVSRLVSGAI 266 V+ ++ +A M HI Y + G P A +S++ V R +GA+ Sbjct: 217 DYRFYVLWLSFFFMALAGLMVIGHIAPYAQERGLEPLAAAFAVSILSVANAVGRPGAGAL 276 Query: 267 CDRIGGLRTLLLGSALQGLSLLLFIPFD-SLASLYLISALFGLFQGGIVPSYAIIVREYF 325 D+IG T+ + +QG++L+ F +L ++Y+ +A+ G G + ++F Sbjct: 277 SDKIGRAMTMFVLFLIQGITLIAFPHVALTLITIYICAAIIGFNYGANFSLFPSATGDFF 336 Query: 326 PAAEAGQRVGAVIMATMFGMALGGWMSGKIFDLTGSYHAAF 366 G G V + G +G M+G +FD+TGSY AF Sbjct: 337 GTKNLGVNYGLVFTSYGVGGLVGPIMAGYVFDVTGSYEIAF 377 >BH2694 [GEPR] COG0477 Permeases of the major facilitator superfamily Bha Bacillus halodurans Length = 418 Score = 88.6 bits (218), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 84/357 (23%), Positives = 148/357 (41%), Gaps = 21/357 (5%) Query: 21 AVVLPYVQAHYYVDRGLASMPYTLTMLGVGVGGLLMGRMADRSGITRPMMLGGLCLGGGF 80 A V P+ + + +DRG S+ TL+ + G+ L+G++ DR G + L +G F Sbjct: 31 AFVQPW-ETEFSMDRGSISLISTLSFIVYGISQPLIGKLVDRLGARFILSCSTLLVGVSF 89 Query: 81 LAASWAXAQDIWTFMAVHCILIGLLGTSATFSPLVADTSLWFRKRRGIAVAVCASGNYLG 140 + + A W ++ +++ + A+ + WF K+RG+A + +G G Sbjct: 90 VLTT--MATQPWHLFILYGVVVSIGVGGASNVAATVVITNWFNKKRGLAFGIIEAGFGAG 147 Query: 141 GAIWPPIVQHFVDNYGWQETYRGLGLICILVMCPLALLMRARPPVQDSNAATPRAGG--G 198 I P + W+ T LG +++ P+ LL+ P S GG Sbjct: 148 QMILVPGSLMLIQWLDWKATVVILGFFLAVIVFPIVLLLLRNHP---SEKQVEPIGGVRE 204 Query: 199 PRPFGLAPGSAQL-----------LLCVVGVACC--VAMAMPQVHIVAYCGDLGYGPARG 245 +P SA V+ A C + H++ D G+ + Sbjct: 205 EEETNTSPNSATFSNWSVFRMRPFWFLVLPFAICGFTTTGLMDTHLIPLSHDHGFSTSVT 264 Query: 246 AQMLSLMLACGVVSRLVSGAICDRIGGLRTLLLGSALQGLSLLLFIPFDSLASLYLISAL 305 + +SL+ +V L+SG I DR + L L + LSL++ + L + L Sbjct: 265 SAAVSLLAGFNIVGILLSGVIADRWSSRKFLFLLYVARALSLVILVHSHDPLLLLGFAIL 324 Query: 306 FGLFQGGIVPSYAIIVREYFPAAEAGQRVGAVIMATMFGMALGGWMSGKIFDLTGSY 362 FGL V ++ +YF G +G + ++ G ALG ++ G +++ TGSY Sbjct: 325 FGLVDFATVAPTQLLATQYFKRYSIGLMIGWLFLSHQVGSALGAYVPGLLYEQTGSY 381