BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0030.0187.p (464 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BS_mmr [GEPR] COG0477 Permeases of the major facilitator superfa... 395 e-110 mll2542 [GEPR] COG0477 Permeases of the major facilitator superf... 242 1e-63 Cgl1114 [GEPR] COG0477 Permeases of the major facilitator superf... 209 9e-54 RSp1417 [GEPR] COG0477 Permeases of the major facilitator superf... 206 9e-53 Cgl1213 [GEPR] COG0477 Permeases of the major facilitator superf... 195 2e-49 >BS_mmr [GEPR] COG0477 Permeases of the major facilitator superfamily Bsu Bacillus subtilis Length = 466 Score = 395 bits (1016), Expect = e-110, Method: Compositional matrix adjust. Identities = 212/449 (47%), Positives = 297/449 (66%), Gaps = 1/449 (0%) Query: 5 PLADAAPHAGMLPLVALAIGFVMAMLDVTVVNVGLSNISTNLDAPLSMLVWIVDGYTLTF 64 + ++ G+ L+ LA+GF+MA LDVTVVNV ++++ L LS + W+VDGY LTF Sbjct: 6 SIQESTSSTGISVLIVLALGFLMATLDVTVVNVAMADMKNTLSMSLSGVTWVVDGYILTF 65 Query: 65 AAMLLVGGALADRFGARRLYLTGLFLFVVASLLCGAAPNGPFLIAARLLQGLGAAFFMPS 124 A++LL GGALADRFG++ +Y+ GL +FV+AS LC A+ NG LIA RL+QG+GAA FMPS Sbjct: 66 ASLLLAGGALADRFGSKTIYILGLAVFVMASCLCAASINGQMLIAGRLIQGIGAALFMPS 125 Query: 125 SLSLLTHVYEDDRVRARMLGVWSATVGLAAAAGPLLGGVLIHWLGWRSVFLINVPVGLLG 184 SLSLL Y D+R RARM G+W+A V A+A GP +GGVL+ GW+S+FLINVP+G Sbjct: 126 SLSLLAASYLDERARARMFGLWAALVSAASALGPFIGGVLVQLAGWQSIFLINVPIGAAA 185 Query: 185 LLMARKLIPQVAGHARALHLFSHLAGVVMLAGISFVLIQGPVYGWASPRILAALAVAVLA 244 L+ A +++ +V G + +++ HL G++ L +S+ LIQGP GW SP IL A AVLA Sbjct: 186 LISAYRILSRVPGKSSRVNIIGHLLGMMALGFLSYALIQGPSAGWRSPVILVAFTAAVLA 245 Query: 245 AVALVRHELRGIAPLLPKALFATPQFAAANGIGFLINFGVYGNLFYLALFLQQGRGADAL 304 V + E+ P+LP +L+ +F+AA IGFL+NF ++G +F L+LFLQ+ GA + Sbjct: 246 FVLFLLREISAKTPILPASLYKNGRFSAAQFIGFLLNFALFGGMFMLSLFLQEAGGASSF 305 Query: 305 QTGLQLVPMMAVVFFGNLMSGRMAAHWGPRVPLLLGLSVGTVFTAVAMSF-RPETPYWLL 363 G++L+PMMAV GNL+ R+A + + + ++V + + P+ PYW L Sbjct: 306 MAGVELLPMMAVFVIGNLLFARLANRFEAGQLMFVSMAVSCIIALLLFVLISPDFPYWQL 365 Query: 364 ALVCAAANLGISTAIPSMTTVVMQVAGKAHANSAAAALNANRQIGALVGVALMGAILHSV 423 A++ + NL +P+MTTV+MQ AG+ H N A AALNANRQIGALVGVA+ G I+H Sbjct: 366 AVLMSVMNLCTGITVPAMTTVIMQAAGQRHTNIAGAALNANRQIGALVGVAITGVIIHLS 425 Query: 424 AGWSVRNPLAFGVMALAYGVALWLVWRFV 452 A W AF +M AY +A LVW F+ Sbjct: 426 ATWYAGAGFAFLMMGAAYSLAALLVWLFL 454 >mll2542 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 505 Score = 242 bits (617), Expect = 1e-63, Method: Compositional matrix adjust. Identities = 150/414 (36%), Positives = 232/414 (56%), Gaps = 16/414 (3%) Query: 16 LPLVA-LAIGFVMAMLDVTVVNVGLSNISTNLDAPLSMLVWIVDGYTLTFAAMLLVGGAL 74 LPLVA + +G +A+LDV++VNV L I L L W+VD YTL +A +L G + Sbjct: 6 LPLVAAVYLGTFVALLDVSIVNVALPTIQQALHTDFGGLQWVVDAYTLCLSAFMLSSGLI 65 Query: 75 ADRFGARRLYLTGLFLFVVASLLCGAAPNGPFLIAARLLQGLGAAFFMPSSLSLLTHVYE 134 DR+G +R +L G+ +FV SL+C APN P L+A R++QG+ + +P +LS+LT + Sbjct: 66 GDRYGRKRSWLAGVGIFVAGSLICAVAPNLPALLAGRVVQGIAGSLLIPGALSILTQAFP 125 Query: 135 DDRVRARMLGVWSATVGLAAAAGPLLGGVLIHWLGWRSVFLINVPVGLLGLLMARKLIPQ 194 D R RA ++G W+A ++ GP+LGG+L+ +GW+S+FLIN+P+GL +++ I + Sbjct: 126 DPRERAGVIGGWAAFAAVSLVVGPVLGGILVQTVGWQSIFLINLPLGLFTIVLGAVSIEE 185 Query: 195 VAGHARALHLFSHLAGVVM----LAGISFVLIQGPVYGWASPRILAALAVAVLAAVALVR 250 + H HL L G+ + L ++F LI GW PR + A+ V V+ + Sbjct: 186 TS-HPEHAHL--DLVGLALSILWLGALTFGLISAGESGWGDPRTIVAIIVGVVGLAVFLG 242 Query: 251 HELRGIAPLLPKALFATPQFAAANGIGFLINFGVYGNLFYLALFLQQGRGADALQTGLQL 310 E R P+LP LF +FA AN F + F Y +F+ ++FLQQ +G QTGL++ Sbjct: 243 FEARTPRPMLPLGLFRDVRFAVANVASFALGFTSYSCVFFFSMFLQQVQGWSPTQTGLRM 302 Query: 311 VPMMAVVFFGNLMSGRMAAHWGPRVPLLLGLSVGTVFTAVAMSFR----PETPYWLLALV 366 P V + GR++A +G L ++ G V ++M P TPY LL ++ Sbjct: 303 APAFLVQIVVSPWIGRLSARYGHS----LLMTAGYVLIGLSMLGMCWAGPSTPYALLCVL 358 Query: 367 CAAANLGISTAIPSMTTVVMQVAGKAHANSAAAALNANRQIGALVGVALMGAIL 420 LG S AIP+ + M A + + +A +NA RQ G +G+AL+GA++ Sbjct: 359 FTINGLGNSLAIPTGSAAAMSYAPRERSGMVSAVINATRQSGLAIGIALLGALM 412 >Cgl1114 [GEPR] COG0477 Permeases of the major facilitator superfamily Cgl Corynebacterium glutamicum Length = 449 Score = 209 bits (533), Expect = 9e-54, Method: Compositional matrix adjust. Identities = 143/433 (33%), Positives = 227/433 (52%), Gaps = 27/433 (6%) Query: 20 ALAIGFVMAMLDVTVVNVGLSNISTNLDAPLSMLVWIVDGYTLTFAAMLLVGGALADRFG 79 AL++G + +LD ++V V L I +L A L+ VW+ Y LTFA LL+ G L DR+G Sbjct: 15 ALSVGLFLTLLDQSLVAVALPKIQEDLGASLNQAVWVSAVYLLTFAVPLLITGRLGDRYG 74 Query: 80 ARRLYLTGLFLFVVASLLCGAAPNGPFLIAARLLQGLGAAFFMPSSLSLLTHVYEDDRVR 139 R +YL G+ +F +A+L C AP+ +LIAAR +QGLG + P LS++ ++ DR R Sbjct: 75 QRNIYLAGMAVFTLAALACVFAPSIEWLIAARAVQGLGGSLLNPQPLSIIHKIFAHDR-R 133 Query: 140 ARMLGVWSATVGLAAAAGPLLGGVLIHWLGWRSVFLINVPVGLLGLLMARKLIPQVAGHA 199 GVWSA A GP++GGVL+ W+ WR+VFL+ VP+GL+ L M + +P++ Sbjct: 134 GAATGVWSAVASSAGLFGPVIGGVLVGWISWRAVFLVYVPLGLISLFMVARYVPKLPTGT 193 Query: 200 RALHLFSHLAGVVMLAGISFVLIQGPVYGWASPRILAALAVAVLAAVALVRHELRGIAPL 259 + S +V + G+ L QGP GW + I +LAV + AAV + + R APL Sbjct: 194 SKIDWLSGAVSLVAVLGVVLALQQGPELGWGT-LIWVSLAVGIAAAVLFIWMQTRSKAPL 252 Query: 260 LPKALFATPQFAAANGIGFLINFGVYGNLFYLALFLQQGRGADALQTGLQLVPMMAVVFF 319 +P +F T FA F + F VY + L+LQ +G + GL LVPM + Sbjct: 253 MPLRIFKTRNFAIGAFSIFSLGFTVYSVNLPIMLYLQTAQGMSSQLAGLMLVPMGIISVV 312 Query: 320 GNLMSGRMAAHWGPRV-------PLLLGLSVGTVFTAVAMSFRPETPYWLLALVCAAANL 372 + + GR+ P + L+ +++ VF +S P+WLL + + Sbjct: 313 MSPVIGRLVDRLAPGMISKIGFGALIFSMALMAVFMIANLS-----PWWLLIPIILFGSS 367 Query: 373 GISTAIPSMTTVVMQVAGKAHANSAAAALNANRQIGALVGVALMGAILHSVAGWSVRNPL 432 + P+ + + ++ + SA+ N +RQ+GA++G A +GA++ Sbjct: 368 NAMSFAPN-SVIALRDVPQDLVGSASGFYNTSRQVGAVLGAATLGAVMQ----------- 415 Query: 433 AFGVMALAYGVAL 445 GV +++GVA+ Sbjct: 416 -IGVGTVSFGVAM 427 >RSp1417 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 467 Score = 206 bits (524), Expect = 9e-53, Method: Compositional matrix adjust. Identities = 144/401 (35%), Positives = 213/401 (53%), Gaps = 6/401 (1%) Query: 18 LVALAIGFVMAMLDVTVVNVGLSNISTNLDAPLSMLVWIVDGYTLTFAAMLLVGGALADR 77 L+ +I +MAMLD VV S I +L A LS L W ++ Y L+ AA+L+ G AL DR Sbjct: 14 LILTSIATLMAMLDAMVVATATSAIRADLGASLSALQWTMNAYNLSLAALLMTGAALGDR 73 Query: 78 FGARRLYLTGLFLFVVASLLCGAAPNGPFLIAARLLQGLGAAFFMPSSLSLLTHVYEDDR 137 FG RR+++TGL +FV AS+ C A + +LIAAR++QG G A P S++LL+ + +R Sbjct: 74 FGRRRVFVTGLCVFVAASIACALARSAEWLIAARVVQGAGGALVTPLSMALLSAAFPPER 133 Query: 138 VRARMLGVWSATVGLAAAAGPLLGGVLIHWLGWRSVFLINVPVGLLGLLMARKLIPQVAG 197 R + LG++ GLA GP+LGGV+ L W+ +F +NVP+GL +++A + IP G Sbjct: 134 -RGKALGLFGGITGLALILGPVLGGVIAGNLPWQWIFWLNVPIGLPLIVLAVRRIPDSKG 192 Query: 198 HARALHLFSHLAGVVMLAGISFV--LIQGPVYGWASPRILAALAVAVLAAVALVRHELRG 255 A AL + L +VM A I V L++G GW+ AL V + V E R Sbjct: 193 PAAALDIPGAL--LVMGASIGLVWGLMRGSSKGWSDSEAPLALVVGAAFMICFVLWERRA 250 Query: 256 IAPLLPKALFATPQFAAANGIGFLINFGVYGNLFYLALFLQQGRGADALQTGLQLVPMMA 315 P++P LFA+ F++ FL G+YG +F+L F Q +G D GL+L+P Sbjct: 251 KHPMIPMRLFASRAFSSGIAACFLFYAGMYGVVFFLPQFFQSAQGHDPFAAGLRLLPWTV 310 Query: 316 VVFFGNLMSGRMAAHWGPRVPLLLGLSVGTV-FTAVAMSFRPETPYWLLALVCAAANLGI 374 +FF ++G M G R ++ GL + + F +A + P T Y L + GI Sbjct: 311 TLFFIAPLAGSMVDRIGERSVMVTGLLLQAIGFAWIAWAASPGTSYLNLVAPLVISGAGI 370 Query: 375 STAIPSMTTVVMQVAGKAHANSAAAALNANRQIGALVGVAL 415 S A P+ V+ A+ N R +G G+A+ Sbjct: 371 SMAGPAAQKAVLGAVTVQDIGKASGVFNMFRILGGATGIAI 411 >Cgl1213 [GEPR] COG0477 Permeases of the major facilitator superfamily Cgl Corynebacterium glutamicum Length = 487 Score = 195 bits (495), Expect = 2e-49, Method: Compositional matrix adjust. Identities = 136/415 (32%), Positives = 217/415 (52%), Gaps = 19/415 (4%) Query: 18 LVALAIGFVMAMLDVTVVNVGLSNISTNLDAPLSMLVWIVDGYTLTFAAMLLVGGALADR 77 L+AL IGF M +LD T+V V + ++ A + ++W+ Y LTFA LLV G L D+ Sbjct: 37 LIALCIGFFMILLDQTIVAVSTPALQADMGASYNEVIWVTSVYLLTFAVPLLVTGRLGDK 96 Query: 78 FGARRLYLTGLFLFVVASLLCGAAPNGPFLIAARLLQGLGAAFFMPSSLSLLTHVYEDDR 137 +G + +Y+ G+ +F V+SL CG AP+ LI AR +QGLGAA P +++ + ++ +R Sbjct: 97 YGPKNVYVAGMVIFTVSSLACGLAPDMFTLIIARGVQGLGAALLTPQTMATINRIFAFER 156 Query: 138 VRARMLGVWSATVGLAAAAGPLLGGVLIHWLGWRSVFLINVPVGLLGLLMARKLIPQVAG 197 R LGVW +T GLA+ AGP+LGGV+ GW+ VF INVP+G++ ++ K +P+ Sbjct: 157 -RGAALGVWGSTAGLASLAGPILGGVITENWGWQWVFYINVPIGVISVIAVMKYVPEFPP 215 Query: 198 HARALHLFSHLAGVVMLAGISFVLIQGPVYGWAS---PRILAALAVAVLAAVALVRHELR 254 R L S + +V + + F +G GWA+ I+AA A+ R E Sbjct: 216 LTRPLDPLSIVLSIVAVFFLVFAFQEGEGAGWAAWVWIMIVAAFALFAWFIYQQSRAEKS 275 Query: 255 GIAPLLPKALFATPQFAAANGIGFLINFGVYGNLFYLALFLQQGRGADALQTGLQLVP-- 312 G PL+P +F F+ N + F V G + L+ QQ G +A++ G +VP Sbjct: 276 GNDPLVPLEIFKFRNFSLGNICIMAMGFTVAGTPLPIMLYFQQAHGMNAMEAGFMMVPQA 335 Query: 313 MMAVVFFGNLMSGRMAAHWGPRVPLLLGLS---VGTVFTAVAMSFRPETPYWLLALVCAA 369 +MA V + G++ P + LG S V V ++ M F + L+++ Sbjct: 336 LMAAVL--SPFVGKLVDRSNPGLMAALGFSTVAVSIVLLSMVMIFDTGLVWALVSMTL-- 391 Query: 370 ANLGISTAI---PSMTTVVMQVAGKAHANSAAAALNANRQIGALVGVALMGAILH 421 LGI A P+ T+ + + K + + N RQ+G+++G A +GA++ Sbjct: 392 --LGIGNAFVWAPNSTSTMRDLPHK-FMGAGSGVFNTTRQLGSVIGAAAIGAVMQ 443