BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0030.0177.p (300 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0917 [E] COG0031 Cysteine synthase Rso Ralstonia solanacearum 489 e-138 PA0932 [E] COG0031 Cysteine synthase Pae Pseudomonas aeruginosa 415 e-116 STM2440 [E] COG0031 Cysteine synthase Sty Salmonella typhimurium... 391 e-109 VC0537 [E] COG0031 Cysteine synthase Vch Vibrio cholerae 390 e-108 cysM [E] COG0031 Cysteine synthase Eco Escherichia coli K12 389 e-108 >RSc0917 [E] COG0031 Cysteine synthase Rso Ralstonia solanacearum Length = 300 Score = 489 bits (1258), Expect = e-138, Method: Compositional matrix adjust. Identities = 231/300 (77%), Positives = 266/300 (88%) Query: 1 MSYPTIESTIGNTPLIQLPRIGGEEAKRRNNLILGKLEGNNPAGSVKDRAAYSMITRAEA 60 M+YPTIE TIGNTPL++L RI GE+ RR N+ILGKLEGNNPAGSVKDR A SMI AE Sbjct: 1 MAYPTIEDTIGNTPLVRLQRIPGEDNARRGNVILGKLEGNNPAGSVKDRPALSMIKHAET 60 Query: 61 RGQIKPGDTLIEATSGNTGIALAMVAAMRGYKMVLLMPENLSEERRQSMAAYGAKIVLTP 120 RG+IKPGDTLIEATSGNTGIALAM AA+RGYKMVL+MPE+LS ERRQSMAAYGA+IVLTP Sbjct: 61 RGRIKPGDTLIEATSGNTGIALAMAAAIRGYKMVLIMPEDLSVERRQSMAAYGAEIVLTP 120 Query: 121 KSGGMEYARDLAEQMQKNGEGLILDQFANADNPLAHYETTGPEIWRDTKGSITHFVSAMG 180 GGMEYARDLA+ M+++G+G+ILDQFAN DNPLAHYE TGPEIWRDT+G ITHFVSAMG Sbjct: 121 VKGGMEYARDLADAMERDGKGVILDQFANPDNPLAHYEGTGPEIWRDTEGRITHFVSAMG 180 Query: 181 TTGTIMGVSQYLKEQNAQVQIVGAQPEEGSSIPGIRKWPEAYLPKIFDRSRVDQVESVSQ 240 TTGTI GVS++LKE+N +QIVGAQP EGS IPGIRKWPEAY+PKI+D +D+ ESVSQ Sbjct: 181 TTGTITGVSRFLKEKNPAIQIVGAQPAEGSRIPGIRKWPEAYMPKIYDPKHIDRTESVSQ 240 Query: 241 ADAENMARKLAVTEGLFCGISAAGACEVAVRLSHQLENATIVFIVCDRGDRYLSTGVFPA 300 +DAE+MAR++A EG+FCGISAAGA VA+R++ +ENATIVF+VCDRGDRYLSTGVFPA Sbjct: 241 SDAEHMARRMAREEGIFCGISAAGALCVALRVAEAVENATIVFVVCDRGDRYLSTGVFPA 300 >PA0932 [E] COG0031 Cysteine synthase Pae Pseudomonas aeruginosa Length = 299 Score = 415 bits (1066), Expect = e-116, Method: Compositional matrix adjust. Identities = 195/298 (65%), Positives = 242/298 (81%), Gaps = 4/298 (1%) Query: 1 MSYPTIESTIGNTPLIQLPRIGGEEAKRRNNLILGKLEGNNPAGSVKDRAAYSMITRAEA 60 + YPTI +GNTPL++L R+ GE + N +L KLEGNNPAGSVKDR A SMITRAE Sbjct: 3 VQYPTIADCVGNTPLVRLQRLPGETS----NTLLVKLEGNNPAGSVKDRPALSMITRAEL 58 Query: 61 RGQIKPGDTLIEATSGNTGIALAMVAAMRGYKMVLLMPENLSEERRQSMAAYGAKIVLTP 120 RG I+PGDTLIEATSGNTGIALAM AA++GYKM+L+MP+N + ER+ +M AYGA+++L Sbjct: 59 RGDIRPGDTLIEATSGNTGIALAMAAAIKGYKMILIMPDNSTAERKAAMTAYGAELILVS 118 Query: 121 KSGGMEYARDLAEQMQKNGEGLILDQFANADNPLAHYETTGPEIWRDTKGSITHFVSAMG 180 K GME ARDLA+++Q+ G G +LDQFAN DNP AHY +TGPEIW+ T GSITHFVS+MG Sbjct: 119 KEEGMEGARDLADKLQREGRGKVLDQFANGDNPEAHYHSTGPEIWQQTGGSITHFVSSMG 178 Query: 181 TTGTIMGVSQYLKEQNAQVQIVGAQPEEGSSIPGIRKWPEAYLPKIFDRSRVDQVESVSQ 240 TTGTIMGVS+YLKEQN VQIVG QP EGS+IPGIR+WP+ YLPKI+D SRVD+V + Q Sbjct: 179 TTGTIMGVSRYLKEQNPAVQIVGLQPMEGSAIPGIRRWPQEYLPKIYDASRVDRVVDMHQ 238 Query: 241 ADAENMARKLAVTEGLFCGISAAGACEVAVRLSHQLENATIVFIVCDRGDRYLSTGVF 298 +AE++ R+LA EG+FCG+S+ GA +RLS +LENA +V I+CDRGDRYLS+GV+ Sbjct: 239 DEAEDIMRRLAREEGIFCGVSSGGAVAAMLRLSRELENAVLVAIICDRGDRYLSSGVY 296 >STM2440 [E] COG0031 Cysteine synthase Sty Salmonella typhimurium LT2 Length = 303 Score = 391 bits (1005), Expect = e-109, Method: Compositional matrix adjust. Identities = 190/294 (64%), Positives = 227/294 (77%), Gaps = 4/294 (1%) Query: 5 TIESTIGNTPLIQLPRIGGEEAKRRNNLILGKLEGNNPAGSVKDRAAYSMITRAEARGQI 64 T+E TIGNTPL++L R+G + I KLEGNNPAGSVKDRAA SMI AE RG+I Sbjct: 3 TLEQTIGNTPLVKLQRLGPDNGSE----IWVKLEGNNPAGSVKDRAALSMIVEAEKRGEI 58 Query: 65 KPGDTLIEATSGNTGIALAMVAAMRGYKMVLLMPENLSEERRQSMAAYGAKIVLTPKSGG 124 KPGD LIEATSGNTGIALAM+AA++GY+M LLMP+N+S+ERR +M AYGA+++L K G Sbjct: 59 KPGDVLIEATSGNTGIALAMIAALKGYRMKLLMPDNMSQERRAAMRAYGAELILVTKEQG 118 Query: 125 MEYARDLAEQMQKNGEGLILDQFANADNPLAHYETTGPEIWRDTKGSITHFVSAMGTTGT 184 ME ARDLA M + GEG +LDQF N DNP AHY TTGPEIWR T G ITHFVS+MGTTGT Sbjct: 119 MEGARDLALAMSERGEGKLLDQFNNPDNPYAHYTTTGPEIWRQTSGRITHFVSSMGTTGT 178 Query: 185 IMGVSQYLKEQNAQVQIVGAQPEEGSSIPGIRKWPEAYLPKIFDRSRVDQVESVSQADAE 244 I GVS++L+EQ V IVG QPEEGSSIPGIR+WP Y+P IF+ S VD+V + Q DAE Sbjct: 179 ITGVSRFLREQEKPVTIVGLQPEEGSSIPGIRRWPAEYMPGIFNASLVDEVLDIHQNDAE 238 Query: 245 NMARKLAVTEGLFCGISAAGACEVAVRLSHQLENATIVFIVCDRGDRYLSTGVF 298 N R+LAV EG+FCG+S+ GA A+R++ A +V I+CDRGDRYLSTGVF Sbjct: 239 NTMRELAVREGIFCGVSSGGAVAGALRVARATPGAIVVAIICDRGDRYLSTGVF 292 >VC0537 [E] COG0031 Cysteine synthase Vch Vibrio cholerae Length = 295 Score = 390 bits (1002), Expect = e-108, Method: Compositional matrix adjust. Identities = 184/296 (62%), Positives = 235/296 (79%), Gaps = 5/296 (1%) Query: 3 YPTIESTIGNTPLIQLPRIGGEEAKRRNNLILGKLEGNNPAGSVKDRAAYSMITRAEARG 62 +PT+E +G TPL++L R+ A R L+ KLEGNNPAGSVKDR A +MI +AEARG Sbjct: 4 FPTLEDYVGQTPLVRLQRL---NAGRSTVLV--KLEGNNPAGSVKDRPALNMIVQAEARG 58 Query: 63 QIKPGDTLIEATSGNTGIALAMVAAMRGYKMVLLMPENLSEERRQSMAAYGAKIVLTPKS 122 ++PGDT+IEATSGNTGIALAM AA++GYKM+L+MP+N ++ER+ SM AYGA+++L K Sbjct: 59 SLQPGDTIIEATSGNTGIALAMAAAIKGYKMILIMPDNATQERKDSMRAYGAELILVSKE 118 Query: 123 GGMEYARDLAEQMQKNGEGLILDQFANADNPLAHYETTGPEIWRDTKGSITHFVSAMGTT 182 GME ARDLA QMQ+ G+G +LDQF N DNP AHY +TGPEIW+ ++G ITHFVS+MGTT Sbjct: 119 QGMEGARDLALQMQQEGKGKVLDQFNNLDNPDAHYRSTGPEIWQQSQGKITHFVSSMGTT 178 Query: 183 GTIMGVSQYLKEQNAQVQIVGAQPEEGSSIPGIRKWPEAYLPKIFDRSRVDQVESVSQAD 242 GTIMGVS+YLK+QN Q+QI+G QP EGS+IPGIR+WP+AYLP IFD +RVDQV V+Q D Sbjct: 179 GTIMGVSRYLKQQNPQIQIIGLQPSEGSAIPGIRRWPQAYLPGIFDAARVDQVLDVTQTD 238 Query: 243 AENMARKLAVTEGLFCGISAAGACEVAVRLSHQLENATIVFIVCDRGDRYLSTGVF 298 AE AR LA EG+ G+S+ GA A++++ Q + +V IVCDRGDRYLS+G+F Sbjct: 239 AEQTARALAREEGICAGVSSGGAVFAALQIAQQNPGSVVVAIVCDRGDRYLSSGLF 294 >cysM [E] COG0031 Cysteine synthase Eco Escherichia coli K12 Length = 303 Score = 389 bits (999), Expect = e-108, Method: Compositional matrix adjust. Identities = 188/294 (63%), Positives = 229/294 (77%), Gaps = 4/294 (1%) Query: 5 TIESTIGNTPLIQLPRIGGEEAKRRNNLILGKLEGNNPAGSVKDRAAYSMITRAEARGQI 64 T+E TIGNTPL++L R+G + + KLEGNNPAGSVKDRAA SMI AE RG+I Sbjct: 3 TLEQTIGNTPLVKLQRMGPDNGSE----VWLKLEGNNPAGSVKDRAALSMIVEAEKRGEI 58 Query: 65 KPGDTLIEATSGNTGIALAMVAAMRGYKMVLLMPENLSEERRQSMAAYGAKIVLTPKSGG 124 KPGD LIEATSGNTGIALAM+AA++GY+M LLMP+N+S+ERR +M AYGA+++L K G Sbjct: 59 KPGDVLIEATSGNTGIALAMIAALKGYRMKLLMPDNMSQERRAAMRAYGAELILVTKEQG 118 Query: 125 MEYARDLAEQMQKNGEGLILDQFANADNPLAHYETTGPEIWRDTKGSITHFVSAMGTTGT 184 ME ARDLA +M GEG +LDQF N DNP AHY TTGPEIW+ T G ITHFVS+MGTTGT Sbjct: 119 MEGARDLALEMANRGEGKLLDQFNNPDNPYAHYTTTGPEIWQQTGGRITHFVSSMGTTGT 178 Query: 185 IMGVSQYLKEQNAQVQIVGAQPEEGSSIPGIRKWPEAYLPKIFDRSRVDQVESVSQADAE 244 I GVS++++EQ+ V IVG QPEEGSSIPGIR+WP YLP IF+ S VD+V + Q DAE Sbjct: 179 ITGVSRFMREQSKPVTIVGLQPEEGSSIPGIRRWPTEYLPGIFNASLVDEVLDIHQRDAE 238 Query: 245 NMARKLAVTEGLFCGISAAGACEVAVRLSHQLENATIVFIVCDRGDRYLSTGVF 298 N R+LAV EG+FCG+S+ GA A+R++ +A +V I+CDRGDRYLSTGVF Sbjct: 239 NTMRELAVREGIFCGVSSGGAVAGALRVAKANPDAVVVAIICDRGDRYLSTGVF 292