BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0030.0164.p (488 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA2689 [R] COG2819 Predicted hydrolase of the alpha/beta superfa... 197 4e-50 STM2776 [R] COG2819 Predicted hydrolase of the alpha/beta superf... 168 2e-41 BS_yuiI [R] COG2819 Predicted hydrolase of the alpha/beta superf... 111 3e-24 MA3757 [M] COG0438 Glycosyltransferase Mac Methanosarcina acetiv... 102 2e-21 Cj1376 [R] COG2819 Predicted hydrolase of the alpha/beta superfa... 99 2e-20 >PA2689 [R] COG2819 Predicted hydrolase of the alpha/beta superfamily Pae Pseudomonas aeruginosa Length = 304 Score = 197 bits (501), Expect = 4e-50, Method: Compositional matrix adjust. Identities = 106/199 (53%), Positives = 127/199 (63%), Gaps = 2/199 (1%) Query: 12 QPDLSRPLGPTIADTGSAWYRFSRFTLGSVDGQRSYRITLGVPLRPPPPQGYPAIVLLDG 71 QPD + ++ YRFS L SVDGQR YR+ LG PL+ PP GYP + +LDG Sbjct: 26 QPDPEATMDRSLLQRQDLPYRFSAVDLDSVDGQRHYRLWLGRPLQAPPAAGYPVVWMLDG 85 Query: 72 NAALAAIDEPQLQALQEGSPPVIVAVGYDTPLRFDVAARAYDYTPPIPAGQVDDETS-RG 130 NAA+ A+DE L+ L +G P++VA+GY TPLR D A R +DYTP P GQ D G Sbjct: 86 NAAVGALDESTLRRLADGDAPLLVAIGYRTPLRIDRAGRTFDYTPASP-GQADQRDPLNG 144 Query: 131 RRGGGATVFLDLLQDRILPQVRQQVALDATQLSLWGHSYGGLFVLHTLFTRPGLFSRYIA 190 GGA FLDLL+D + P V Q LD + +LWGHSYGGL VLH LFTRPG F+RY A Sbjct: 145 LPSGGADAFLDLLRDGMRPAVAAQAPLDTARQTLWGHSYGGLLVLHALFTRPGEFARYAA 204 Query: 191 ASPSLWWQGGVILQEEQGF 209 ASPSLWW+ G IL E G Sbjct: 205 ASPSLWWRDGAILGERAGL 223 >STM2776 [R] COG2819 Predicted hydrolase of the alpha/beta superfamily Sty Salmonella typhimurium LT2 Length = 311 Score = 168 bits (426), Expect = 2e-41, Method: Compositional matrix adjust. Identities = 106/268 (39%), Positives = 142/268 (52%), Gaps = 23/268 (8%) Query: 4 CLPAWAAAQPDLSRPLGPTIADTGSAWYRFSRFTLGSVDGQRSYRITLGVPLRPPPPQGY 63 C A + AQPD+ +PLGP IAD GS +Y F S DG R YR+ +P + PP GY Sbjct: 21 CFSALSYAQPDM-QPLGPNIADKGSGYYHFRVNDFQSADGARHYRVWTAIPNKAAPPSGY 79 Query: 64 PAIVLLDGNAALAAIDEPQLQALQEGSPPVIVAVGYDTPLRFDVAARAYDYTPPIPAGQV 123 P + +LDGNA + + E L+ L + SPPVIVA+GY T L FD+ RAYDYT P P Sbjct: 80 PVLYMLDGNAVMDRLPETLLKQLADHSPPVIVAIGYQTNLPFDLNGRAYDYT-PAPGIDR 138 Query: 124 DDETSR---GRRGGGATVFLDLLQDRILPQVRQQVALDATQLSLWGHSYGGLFVLHTLFT 180 DD + R+ GG F LL+ I PQV Q + +++ + +WGHSYGGLFVL + + Sbjct: 139 DDSENNPRFHRKTGGGPAFRQLLERHIAPQVEQGITINSERRGVWGHSYGGLFVLDSWLS 198 Query: 181 RPGLFSRYIAASPSLWWQGGVILQEEQGFPGAAIAWPTACC--------ASAAPGRTXRG 232 F Y +ASPSL V+L P+ C SA+ G + R Sbjct: 199 S-SFFHIYYSASPSLSRDNFVLLNR------LTTVKPSLFCHKKLIIMEGSASNGDS-RQ 250 Query: 233 YRMADRLLCVSRTWQDILQHEHGVRAEL 260 +MA+ L V T + + +GV A L Sbjct: 251 RQMAELLQKVQETVRTL--ENNGVNAAL 276 >BS_yuiI [R] COG2819 Predicted hydrolase of the alpha/beta superfamily Bsu Bacillus subtilis Length = 314 Score = 111 bits (278), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 64/180 (35%), Positives = 95/180 (52%), Gaps = 10/180 (5%) Query: 38 LGSVDGQRSYRITLGVPLRPPPPQGYPAIVLLDGNAALAAIDEP-QLQALQEGS----PP 92 + S + R+Y I + P PPPP GYP I LLD N+ + E ++Q + P Sbjct: 52 MSSRNENRTYHIFISKPSTPPPPAGYPVIYLLDANSVFGTMTEAVRIQGRRPEKTGVIPA 111 Query: 93 VIVAVGYDTPLRFDVAARAYDYTPPIPAGQVDDETSRGRR---GGGATVFLDLLQDRILP 149 VIV +GY+T F +AR D+T P ++ E GR GGA F +++ + P Sbjct: 112 VIVGIGYETAEPFS-SARHRDFTMPTAQSKLP-ERPDGREWPEHGGAEGFFRFIEEDLKP 169 Query: 150 QVRQQVALDATQLSLWGHSYGGLFVLHTLFTRPGLFSRYIAASPSLWWQGGVILQEEQGF 209 ++ + +D + +++GHS GGLFVL L T+P F YIA SPS+ W IL++ F Sbjct: 170 EIERDYQIDKKRQTIFGHSLGGLFVLQVLLTKPDAFQTYIAGSPSIHWNKPFILKKTDHF 229 >MA3757 [M] COG0438 Glycosyltransferase Mac Methanosarcina acetivorans str.C2A Length = 351 Score = 102 bits (255), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 67/248 (27%), Positives = 125/248 (50%), Gaps = 16/248 (6%) Query: 231 RGYRMADRLLCVSR-TWQDILQH----EHGVRAELVSNGVDMLRHSPRPMHPXREAVRRA 285 +G R A++++ VS + ++I ++ E + E++ VD H+ + + +++ Sbjct: 114 KGLRKAEKIITVSEFSKKEIGKYIKYPEENI--EIIHPAVD---HNLYYRNRNKMILKKY 168 Query: 286 QGLTGKPLLLAVGGVEPRKNTLGILQAFVRLRRVYPQAQLVIAGGASVLDHAGYQRVFQA 345 + ++L VG EPRKN I+ +F L++ P+ +L+ G ++ G +R Sbjct: 169 GIKDNEKVILYVGAEEPRKNVQFIINSFSNLKKRIPEVKLLKVGMP---NYPGVRRKLIQ 225 Query: 346 ELAAAALPADAVRILGQVDDADMPSLFRCADVLVFPSLKEGFGLVVLEAMASGVPVVVSR 405 ++ + L D + G V + + ++ D+ VFPSL EGFG+ LEAMA G PV+ S Sbjct: 226 QIESLNLQKDII-FAGYVSELALAEIYNAVDLFVFPSLYEGFGIPPLEAMACGTPVITSN 284 Query: 406 IAPFTEYLDGDCCAWVDPHDPASMAAGIAHALAPA-ARPGLIAAGLEVCARFSWQRSARR 464 + E + GD ++P+D A + L + +I GLE FSW+ SA++ Sbjct: 285 TSSLPEVV-GDAAIQINPYDVEKFAEEMYEVLTNERLKEEMIRKGLERSKMFSWENSAKK 343 Query: 465 HVELYADF 472 +++Y + Sbjct: 344 TLKVYREM 351 >Cj1376 [R] COG2819 Predicted hydrolase of the alpha/beta superfamily Cje Campylobacter jejuni Length = 269 Score = 99.4 bits (246), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 64/210 (30%), Positives = 90/210 (42%), Gaps = 30/210 (14%) Query: 1 MLACLPAWAAAQPDLSRPLGPTIADTGSAWYRFSRFTLGSVDGQRS---YRITLGVPLRP 57 L C A A+P L P A F L +V + Y+I + Sbjct: 6 FLFCSFFLAFAKPSLEIPKLSKQAK--------QNFILENVKFNYNGTIYKIFIAKNKNE 57 Query: 58 PPPQGYPAIVLLDGNAA----LAAIDEPQLQALQEGSPPVIVAVGYDTPLRFDVAARAYD 113 Y I LLDGNA L + P + L +I+ +GYD L FD R D Sbjct: 58 NSNYKYKIIYLLDGNAFFPLFLNLFNTPVKENL------LIIGIGYDNNLAFDTQKRTKD 111 Query: 114 YTPPIPAGQVDDETSRGRRGGGATVFLDLLQDRILPQVRQQVALDATQLSLWGHSYGGLF 173 YTP T+ ++GGG+ F + L +++P + + +D + L+GHS+GGLF Sbjct: 112 YTPT---------TNLNKQGGGSKEFRNFLITQLIPYINKMYPIDFSHQILFGHSFGGLF 162 Query: 174 VLHTLFTRPGLFSRYIAASPSLWWQGGVIL 203 + TL +FS Y SPSLWW L Sbjct: 163 AIDTLLYDSKIFSHYFIISPSLWWDNSEFL 192