BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0030.0099.p (466 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA1262 [GEPR] COG0477 Permeases of the major facilitator superfa... 204 4e-52 lin2977 [GEPR] COG0477 Permeases of the major facilitator superf... 178 2e-44 Cgl1213 [GEPR] COG0477 Permeases of the major facilitator superf... 160 5e-39 mll2542 [GEPR] COG0477 Permeases of the major facilitator superf... 158 3e-38 CAP0109 [GEPR] COG0477 Permeases of the major facilitator superf... 150 4e-36 >PA1262 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 480 Score = 204 bits (518), Expect = 4e-52, Method: Compositional matrix adjust. Identities = 162/416 (38%), Positives = 235/416 (56%), Gaps = 10/416 (2%) Query: 1 LLVGAFLPPLDFFIVNVALPSIRNGLGADPAEVQLVISGYAAVYAVFLITGGRLGDLLGR 60 LL G LP +DF IVNVAL ++ + LGA E++L+++ Y +AV L GGRLGD GR Sbjct: 18 LLAGQLLPMIDFSIVNVALDALAHSLGASETELELIVAVYGVAFAVCLAMGGRLGDNYGR 77 Query: 61 KRVFLAGLAGFGLASTLCGVASSPAMLIAGRLLQGLSAAIMAPQGLASIQALFPERERAR 120 +R+F+ G+A F +AS LCG+A S +L+ R LQG+ AA++ PQ LA++ +R Sbjct: 78 RRLFVLGVALFAVASLLCGLAGSVWLLLVARALQGVGAALVVPQILATLHVSLSGHAHSR 137 Query: 121 ALSMYGATIGLAAIVAQAFGGLLIAANLGDLQWRIIFLINLPIVAIVFLVGIPLLPDTRS 180 AL+ YGA GLA +V Q GG L++A++G L WR +FLINLPI + L +P+TR+ Sbjct: 138 ALAAYGAIGGLAFVVGQVLGGFLVSADIGGLGWRSVFLINLPICLGILLCSRRWVPETRA 197 Query: 181 PHAARLDWMGVLLCALTLGLLVVPLVKGPEDGWPWWTCLMLIASPLFAMAFWRHEQRLTQ 240 HAAR+D G LL A + L++PL GP W W L+L A+ WR E R + Sbjct: 198 EHAARVDAPGTLLLAALILCLLLPLALGPSLHWSWPCALLLAAAVPLLAWLWRTELRQER 257 Query: 241 RGATPLVSPKLARVPGLVVG-LVGVLFFYVVSAFFLTFSIYLQEAIGMSALATGLMFIPC 299 R A PL+ P L R+P + G L+ +LFF S F ++ LQ G+S + G FI Sbjct: 258 RQAWPLLPPSLLRLPSIRFGLLLAILFFACWSGFMFALALALQAGAGLSPVQAGNAFIAL 317 Query: 300 GLGFFLGPLMTPAAARRFGRWTPV----LGMSLEVIGALLLSAVVAMARDGQAPALAGVI 355 G +F+ L+T A R G PV LG +++ G LL ++ + R P + + Sbjct: 318 GASYFVSALLTARVAARIG---PVRLLLLGCVIQMCG--LLGLMLTLQRVWPQPGILNLA 372 Query: 356 VALGLIGVGQGIAVPTLVRSVIERAPADGSGMVAGIVNSALQISAALGVAVIGSVF 411 A +IG GQ V + R + PA +G + ++ + Q S LG A++G+VF Sbjct: 373 PATLVIGFGQAFIVSSFFRIGLSEVPAAQAGAGSAMLATVQQASLGLGSALLGAVF 428 >lin2977 [GEPR] COG0477 Permeases of the major facilitator superfamily Lin Listeria innocua Length = 470 Score = 178 bits (452), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 143/437 (32%), Positives = 225/437 (51%), Gaps = 17/437 (3%) Query: 1 LLVGAFLPPLDFFIVNVALPSIRNGLGADPAEVQLVISGYAAVYAVFLITGGRLGDLLGR 60 +++GAF+ LD IVNVALP I L A ++ VISGYA + + LI GRLGD GR Sbjct: 15 IMLGAFISLLDTTIVNVALPDITTALHATSETIEWVISGYALAFGLVLILAGRLGDKFGR 74 Query: 61 KRVFLAGLAGFGLASTLCGVASSPAMLIAGRLLQGLSAAIMAPQGLASIQALFPERERAR 120 K +++ G+ F + S G+A S LI R++QGL+A + PQ A+I ++ + + Sbjct: 75 KNIYIIGITLFLIMSVTAGLAGSENSLIISRVIQGLAAGLFFPQINATIMDMYSGKSLGK 134 Query: 121 ALSMYGATIGLAAIVAQAFGGLLIAANLGDLQWRIIFLINLPIVAIVFLVGIPLLPD-TR 179 + G+ IG+ + GGLLI WR +F +N+P V + ++ + LP T Sbjct: 135 IFGILGSVIGVGTAIGPLTGGLLIELFGATNGWRAVFFVNVPFVLVTLVLAMLYLPKRTV 194 Query: 180 SPHAARLDWMGVLLCALTLGLLVVPLV-KGPEDGWPWWTCLMLIASPLFAMAF-WRHEQR 237 S D GV L + L LL+ PL+ G D P LM ++ PLF + + W Q Sbjct: 195 STKKISFDLPGVGLLTIALLLLLFPLISNGANDFKPIDYLLMALSIPLFIILYKWSVYQE 254 Query: 238 LTQRGATPLVSPKLARVPGLVVG-LVGVLFFYVVSAFFLTFSIYLQEAIGMSALATGLMF 296 ++G PL++P L + V G L+ +++F ++ F S+ Q SA+ +GL Sbjct: 255 --KKGNQPLIAPNLLKNNQFVSGMLLSLVYFAAFTSIFFVLSLTWQTGFNRSAILSGLAI 312 Query: 297 IPCGLGFFLGPLMTPAAARRF----GRWTPVLGMSLEVIGALLLSAVVAMARDGQAPALA 352 P F LG ++ + + RF GR +LG+SL ++G +S V + DG A Sbjct: 313 SP----FALGSVLAASNSYRFIPLLGRKLLMLGVSLVIVGLGTVSIVFHL-NDGAFSAWL 367 Query: 353 GVIVALGLIGVGQGIAVPTLVRSVIERAPADGSGMVAGIVNSALQISAALGVAVIGSVFF 412 + + L + G+G G+ + L + G +G+ N+A +I ++ G+AV+GSVFF Sbjct: 368 -LFLPLFIAGLGSGLTIAPLNSFTLSTVTGLDRGGASGMFNTAQRIGSSFGIAVVGSVFF 426 Query: 413 SLAGRSHTPSSLAHALS 429 G + T +S A A S Sbjct: 427 RTLGNT-TATSKASAFS 442 >Cgl1213 [GEPR] COG0477 Permeases of the major facilitator superfamily Cgl Corynebacterium glutamicum Length = 487 Score = 160 bits (406), Expect = 5e-39, Method: Compositional matrix adjust. Identities = 127/417 (30%), Positives = 209/417 (50%), Gaps = 22/417 (5%) Query: 1 LLVGAFLPPLDFFIVNVALPSIRNGLGADPAEVQLVISGYAAVYAVFLITGGRLGDLLGR 60 L +G F+ LD IV V+ P+++ +GA EV V S Y +AV L+ GRLGD G Sbjct: 40 LCIGFFMILLDQTIVAVSTPALQADMGASYNEVIWVTSVYLLTFAVPLLVTGRLGDKYGP 99 Query: 61 KRVFLAGLAGFGLASTLCGVASSPAMLIAGRLLQGLSAAIMAPQGLASIQALFPERERAR 120 K V++AG+ F ++S CG+A LI R +QGL AA++ PQ +A+I +F R Sbjct: 100 KNVYVAGMVIFTVSSLACGLAPDMFTLIIARGVQGLGAALLTPQTMATINRIFAFERRGA 159 Query: 121 ALSMYGATIGLAAIVAQAFGGLLIAANLGDLQWRIIFLINLPIVAIVFLVGIPLLPDTRS 180 AL ++G+T GLA++ GG +I N G W+ +F IN+PI I + + +P+ Sbjct: 160 ALGVWGSTAGLASLAGPILGG-VITENWG---WQWVFYINVPIGVISVIAVMKYVPEF-P 214 Query: 181 PHAARLDWMGVLLCALTLGLLVVPLVKGPEDGWPWWTCLMLIASPLFAMAFW--RHEQRL 238 P LD + ++L + + LV +G GW W +M++A+ FA+ W + R Sbjct: 215 PLTRPLDPLSIVLSIVAVFFLVFAFQEGEGAGWAAWVWIMIVAA--FALFAWFIYQQSRA 272 Query: 239 TQRGATPLVSPKLARVPGLVVGLVGVLFF-YVVSAFFLTFSIYLQEAIGMSALATGLMFI 297 + G PLV ++ + +G + ++ + V+ L +Y Q+A GM+A+ G M + Sbjct: 273 EKSGNDPLVPLEIFKFRNFSLGNICIMAMGFTVAGTPLPIMLYFQQAHGMNAMEAGFMMV 332 Query: 298 PCGLGFFLGPLMTPAAARRFGRWTP----VLGMSLEVIGALLLSAVVAMARDGQAPALAG 353 P L + +++P + R P LG S + +LLS V+ L Sbjct: 333 PQAL---MAAVLSPFVGKLVDRSNPGLMAALGFSTVAVSIVLLSMVMIFDT-----GLVW 384 Query: 354 VIVALGLIGVGQGIAVPTLVRSVIERAPADGSGMVAGIVNSALQISAALGVAVIGSV 410 +V++ L+G+G S + P G +G+ N+ Q+ + +G A IG+V Sbjct: 385 ALVSMTLLGIGNAFVWAPNSTSTMRDLPHKFMGAGSGVFNTTRQLGSVIGAAAIGAV 441 >mll2542 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 505 Score = 158 bits (399), Expect = 3e-38, Method: Compositional matrix adjust. Identities = 125/409 (30%), Positives = 209/409 (51%), Gaps = 12/409 (2%) Query: 3 VGAFLPPLDFFIVNVALPSIRNGLGADPAEVQLVISGYAAVYAVFLITGGRLGDLLGRKR 62 +G F+ LD IVNVALP+I+ L D +Q V+ Y + F+++ G +GD GRKR Sbjct: 14 LGTFVALLDVSIVNVALPTIQQALHTDFGGLQWVVDAYTLCLSAFMLSSGLIGDRYGRKR 73 Query: 63 VFLAGLAGFGLASTLCGVASSPAMLIAGRLLQGLSAAIMAPQGLASIQALFPE-RERARA 121 +LAG+ F S +C VA + L+AGR++QG++ +++ P L+ + FP+ RERA Sbjct: 74 SWLAGVGIFVAGSLICAVAPNLPALLAGRVVQGIAGSLLIPGALSILTQAFPDPRERAGV 133 Query: 122 LSMYGATIGLAAIVAQAFGGLLIAANLGDLQWRIIFLINLPIVAIVFLVGIPLLPDTRSP 181 + + A ++ +V GG+L+ + W+ IFLINLP+ ++G + +T P Sbjct: 134 IGGWAAFAAVSLVVGPVLGGILVQT----VGWQSIFLINLPLGLFTIVLGAVSIEETSHP 189 Query: 182 HAARLDWMGVLLCALTLGLLVVPLVKGPEDGWPWWTCLMLIASPLFAMAFWRHEQRLTQR 241 A LD +G+ L L LG L L+ E GW ++ I + +A + + T R Sbjct: 190 EHAHLDLVGLALSILWLGALTFGLISAGESGWGDPRTIVAIIVGVVGLAVFLGFEARTPR 249 Query: 242 GATPLVSPKLARVPGLVVGLVGVLFFYVVSAFFLTFSIYLQEAIGMSALATGLMFIPCGL 301 PL + R V + F FF FS++LQ+ G S TGL P Sbjct: 250 PMLPLGLFRDVRFAVANVASFALGFTSYSCVFF--FSMFLQQVQGWSPTQTGLRMAPA-- 305 Query: 302 GFFLGPLMTPAAARRFGRWTPVLGMSLEVIGALLLSAVVAMARDGQAPALAGVIVALGLI 361 F + +++P R R+ L M+ + L+ +++ M G + A + V + Sbjct: 306 -FLVQIVVSPWIGRLSARYGHSLLMTAGYV--LIGLSMLGMCWAGPSTPYALLCVLFTIN 362 Query: 362 GVGQGIAVPTLVRSVIERAPADGSGMVAGIVNSALQISAALGVAVIGSV 410 G+G +A+PT + + AP + SGMV+ ++N+ Q A+G+A++G++ Sbjct: 363 GLGNSLAIPTGSAAAMSYAPRERSGMVSAVINATRQSGLAIGIALLGAL 411 >CAP0109 [GEPR] COG0477 Permeases of the major facilitator superfamily Cac Clostridium acetobutylicum Length = 545 Score = 150 bits (380), Expect = 4e-36, Method: Compositional matrix adjust. Identities = 116/419 (27%), Positives = 204/419 (48%), Gaps = 22/419 (5%) Query: 1 LLVGAFLPPLDFFIVNVALPSIRNGLGADPAEVQLVISGYAAVYAVFLITGGRLGDLLGR 60 +++G F+ LD IVN+ LP + + + V++ Y +AV ++T RL D GR Sbjct: 13 IVLGFFMTLLDTTIVNITLPKMTEYFNTNMNHISWVVNAYNLAFAVIILTASRLADQFGR 72 Query: 61 KRVFLAGLAGFGLASTLCGVASSPAMLIAGRLLQGLSAAIMAPQGLASIQALFPERERAR 120 K++F+ G+ F +AS L G+++S +LI R LQGLSAA + P + +FP +R Sbjct: 73 KKIFIGGVFLFTIASLLAGISNSLEVLIFLRALQGLSAAFVVPVTMPLSAEIFPPEKRGT 132 Query: 121 ALSMYGATIGLAAIVAQAFGGLLIAANLGDLQWRIIFLINLPIVAIVFLVGIPLLPDTRS 180 +S++GA GLAA GG+L WR IF IN+PI + + I + ++ Sbjct: 133 IMSLWGAFAGLAAASGPTLGGILTQF----FNWRYIFFINVPIGCLCIFLTIKFIKESYD 188 Query: 181 PHAAR-LDWMGVLLCALTLGLLVVPLVKGPEDGW-PWWTCLMLIASPLFAMAFWRHEQRL 238 A++ +D+ G + + + L L+K E GW +T + AS + + F E ++ Sbjct: 189 QAASKSIDFGGNITISAAMFFLTFALIKVNEKGWTSSFTLSLFAASAITLIIFIIIELKV 248 Query: 239 TQRGATPLVSPKLARVPGLVVGLVGVLFF---YVVSAFFLTFSIYLQEAIGMSALATGLM 295 + P++S L + G + + + ++FL+F +L + G++ L+ GL+ Sbjct: 249 NE----PMLSLSLFKSLQFTNGSISLFLLGLGMMCGSYFLSF--FLTQIKGLNELSAGLI 302 Query: 296 FIPCGLGFFLGPLMTPAAARRFG-RWTPVLGMSLEVIGALLLSAVVAMARDGQAPALAGV 354 L ++ ++ G R+ G+ L L S++ Q + V Sbjct: 303 ISTMSLSSMFFSIVAAILTKKVGKRFISAFGIFLLCFSCYLNSSLT------QNSSNIDV 356 Query: 355 IVALGLIGVGQGIAVPTLVRSVIERAPADGSGMVAGIVNSALQISAALGVAVIGSVFFS 413 I+ L + G G G+++ TL+ S I P + G+ +GI N + LGVA+ ++F S Sbjct: 357 ILRLIITGAGTGLSMATLLSSTIANVPINKIGIASGIDNMTRTLGTVLGVALFLTIFTS 415