BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0029.0017.p (1262 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp0626 [H] COG1429 Cobalamin biosynthesis protein CobN and rela... 846 0.0 Rv2062c [H] COG1429 Cobalamin biosynthesis protein CobN and rela... 781 0.0 MT2121 [H] COG1429 Cobalamin biosynthesis protein CobN and relat... 780 0.0 alr1689 [H] COG1429 Cobalamin biosynthesis protein CobN and rela... 773 0.0 slr1211 [H] COG1429 Cobalamin biosynthesis protein CobN and rela... 703 0.0 >RSp0626 [H] COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases Rso Ralstonia solanacearum Length = 1379 Score = 846 bits (2185), Expect = 0.0, Method: Compositional matrix adjust. Identities = 427/663 (64%), Positives = 510/663 (76%), Gaps = 18/663 (2%) Query: 4 IVLLTHAPTDLALLAAARAQLPAEFPAVAGYDLQALQSGTDEQGQPLRTLATLLRTELAS 63 IVLLTHA TDL+ L A AQLP F V G LQA+ G D + +A LL +A Sbjct: 9 IVLLTHAGTDLSTLQRATAQLPDGFAGVTGLHLQAI--GDDAR------MADLLAGPIAG 60 Query: 64 AQVIVLRVLGRLGAVAGFPELLRAARAEGRQLIVLSGTGEPDAELAAASTAAPDVQQQAL 123 A+++++RVLGRL A+ G LL RA+GR L+++SGTGEPD ELAA ST P +QQ+ Sbjct: 61 ARIVIVRVLGRLQAIPGIDALLHDTRAQGRALVIVSGTGEPDPELAARSTVPPALQQEVA 120 Query: 124 AYFNGGGSVNLAQLLRCLSDRLLLSGYGYEPAQALPEHGLYHPDLEQDARLDDWLALRAQ 183 AY GG+ NLAQLLRCLSDRLL++G+GY+P ALPEHG+YHP+L A LDDW A+R Sbjct: 121 AYLQAGGTGNLAQLLRCLSDRLLMTGFGYQPPMALPEHGIYHPELAAPATLDDWAAIRNP 180 Query: 184 APAGKPAVGIIFYRAHWLSGNTAFIDALVAALEARGMDVLPVFTSSLRVSASSGAALPPA 243 A P VGI FYRAHWL GNT FID LV AL + ++ LPV+T+SLR ++G +P A Sbjct: 181 A---WPTVGIAFYRAHWLCGNTRFIDQLVDALAEQRLNALPVYTASLRTLDATG--MPAA 235 Query: 244 LAYFAE---GRVDLIINTTSFAMGEITAGGITPAGWSVSVLEQLNRPVLQAITSGMTQDQ 300 L FA+ GR+D ++NTTSFAMG++ A G T AGWSV+ +L+ PV+QAI S MTQ Q Sbjct: 236 LDVFADDGVGRIDALVNTTSFAMGDVNADGPTAAGWSVAAFTRLDVPVVQAIASSMTQAQ 295 Query: 301 WQHSTRGMNPLDAAMNVVLPEFDGRIIGVPLSFKHTSEAGVVQYQALPDRVRRIAGLAQR 360 W S RG+NPLD AMNV LPEFDGRI+ VP+SFK E Y LPDRVRR+AG+ R Sbjct: 296 WAASERGLNPLDTAMNVALPEFDGRIVSVPMSFK--DERDETAYAPLPDRVRRVAGIVAR 353 Query: 361 LVRLRRTPNAEKRIAFIFTNSSSKAAQIGNAVGLDAPESLMAVLRALAADGYAIGDLPDT 420 V LRRT A+KRIAF+FTNSSSKA+QIGNAVGLD+P SL+ +LRA+ A GY I LP++ Sbjct: 354 QVALRRTAPADKRIAFLFTNSSSKASQIGNAVGLDSPASLLTLLRAMQAQGYRIDGLPES 413 Query: 421 GTALIHELVDRCSYDDILLTEDQLRRAAARIPAARYAQWFAALPAALQARMQRQWGAAPG 480 G ALIH L+DR +YD+ L+ QL +A A +PAARYA WF+ LPA LQ +M+++WG APG Sbjct: 414 GDALIHALIDRGAYDEDYLSAAQLEQAIATVPAARYAAWFSDLPAPLQDKMRQRWGDAPG 473 Query: 481 EAYVHDQHLVIAGLDLGNAFVALQPPRGYGMDPDAIYHQPDLPPTHHYYALYRWLDEEWG 540 AYVHD LV AG++ GNAFVALQPPRGYGMDPDAIYH PDLPPTHHYYALYRWL +EW Sbjct: 474 NAYVHDGKLVFAGMEYGNAFVALQPPRGYGMDPDAIYHTPDLPPTHHYYALYRWLRDEWR 533 Query: 541 ADAIVHVGKHGTLEWLPGKGVGLSEECFPDALLGDVPLFYPFIINDPGEGSQAKRRAHAV 600 ADAIVHVGKHGTLEWLPGKGVG+S+ CFPDALLGD+PLFYPFI+NDPGEGSQAKRRAHAV Sbjct: 534 ADAIVHVGKHGTLEWLPGKGVGVSQTCFPDALLGDLPLFYPFILNDPGEGSQAKRRAHAV 593 Query: 601 VVDHLTPPMTTADSYGALAQLTQLVDEYYQVEVLDPAKLPLLQQQIWELVRQTNLDTDLQ 660 ++DHLTPPMTTAD+YG LAQLTQLVDEYYQVE+LDPAKLPLLQQQIW+L+++ LD DL Sbjct: 594 IIDHLTPPMTTADTYGPLAQLTQLVDEYYQVEMLDPAKLPLLQQQIWDLIKEARLDADLA 653 Query: 661 YKL 663 L Sbjct: 654 AML 656 Score = 508 bits (1307), Expect = e-143, Method: Compositional matrix adjust. Identities = 254/432 (58%), Positives = 315/432 (72%), Gaps = 8/432 (1%) Query: 710 LPHALSELDGAGVAHLIEDLDGYLCELGAAQIRDGLHILGRMPDAQQLPDMLVALTRLPN 769 +P +L+++DG VAHLIED+DGYLCELGAAQIRDGLH+LGR+P L DM+ A+ RLPN Sbjct: 769 VPLSLAKMDGVDVAHLIEDIDGYLCELGAAQIRDGLHVLGRVPADDALVDMVCAMVRLPN 828 Query: 770 QDLPGLQEEVARLFGLSLDMLLEHKGRRLN-IDDALSRTAGRAIVTRADALEAIDALCLS 828 +P L VA GL+ D L KG+RL + L R A R +VTRADAL+A+ AL + Sbjct: 829 LGVPSLPAGVAEALGLAWDALQHDKGKRLEAVSPPLQRLADRPLVTRADALDAVSALTRA 888 Query: 829 LMQALQHQGFAVPAIEGVIQTLFAPLFXAIKATDTGAVRRILSFACEQLVPRLQRTDEEI 888 L+ AL GF + + ++ + TGA+R+ L+F C +LVP L RT EEI Sbjct: 889 LIAALAEHGFDATRSDAALASVLPGI------AHTGAIRQTLAFVCRELVPNLARTTEEI 942 Query: 889 SNLLNGLRGGYIPAGPSGSPTRGMAHILPTGRNFYSVDPRSVPSQSAWRVGQQLAREVLE 948 NLL+GL GGY+PAGPSG+PTRGMAH+LPTGRNFYSVDPRS+PSQ+AWR+G LA E L Sbjct: 943 GNLLHGLAGGYVPAGPSGAPTRGMAHVLPTGRNFYSVDPRSLPSQAAWRIGTALANEALA 1002 Query: 949 RHHRESGDYPESVAISIWGTSAMRTHGDDVAQILSLMGAQPVWREGNRQVAGVELIPLDQ 1008 RH E+G PESV+IS+WGTSAMRTHGDD+AQIL+L+G +P W+ +R+VAG+E+IPL + Sbjct: 1003 RHRTETGHDPESVSISVWGTSAMRTHGDDIAQILALLGVRPRWQAESRRVAGIEVIPLAE 1062 Query: 1009 LQRPRIDVTTRISGFFRDAFPQLIELIDDAVQLAIAADEPEDMNFVRKHYLRDLQQAMQG 1068 L RPRIDVT RISGFFRDAFP LI L+D+AV DEP + NFVRKHYL DL + Sbjct: 1063 LGRPRIDVTVRISGFFRDAFPHLIHLVDEAVHTVARLDEPVERNFVRKHYLADLAHQLFA 1122 Query: 1069 GLGQAEAAAQASYRVFGAKPGSYGAGILPLIQEKNWQDQADFAEAYINWGGYAYGRXRDL 1128 GL A + YRVFG++PG+YGAGILPLIQE++WQD ADFA+AYINWGGYAYGR RD Sbjct: 1123 GLPPEAAEQRTLYRVFGSRPGTYGAGILPLIQEQHWQDDADFAQAYINWGGYAYGR-RDN 1181 Query: 1129 KEETLRVFRARV 1140 + FR R+ Sbjct: 1182 GTDARADFRHRL 1193 Score = 192 bits (489), Expect = 3e-48, Method: Compositional matrix adjust. Identities = 88/128 (68%), Positives = 107/128 (83%) Query: 1126 RDLKEETLRVFRARVVNPKWLASIRRHGYKGGLELTATVDYLFGYDATAQVMEDWMYQQL 1185 R LKEETLRVFR+RV NPKW+A I++HGYKGGLELTATVDYLFGYDATA V++DW+Y+QL Sbjct: 1251 RSLKEETLRVFRSRVANPKWIAGIQKHGYKGGLELTATVDYLFGYDATAHVVDDWVYEQL 1310 Query: 1186 AETYGFDPAMREFLEQANPWAQNAIAERLLEAASRGMWQTPAVQTIEQLRSLYLHSEALL 1245 A+ Y FDPAM++FL ++NPWA NAI ERLLEA R MW P T+ L++L+L SEA+L Sbjct: 1311 AQAYAFDPAMQQFLAESNPWALNAITERLLEAIQRQMWAEPKPDTVAALQALHLRSEAML 1370 Query: 1246 EARGETVR 1253 EARGET + Sbjct: 1371 EARGETTQ 1378 >Rv2062c [H] COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases Mtu Mycobacterium tuberculosis H37Rv Length = 1194 Score = 781 bits (2016), Expect = 0.0, Method: Compositional matrix adjust. Identities = 507/1316 (38%), Positives = 691/1316 (52%), Gaps = 242/1316 (18%) Query: 36 LQALQSGTDEQ-GQPLRTLATLLRTELASAQVIVLRVLGRLGAVAGFPELLRAARAEGRQ 94 + A SG + + P R L LA A ++V+R+LG A + + A G Sbjct: 17 ISARSSGKNYRWANPSRLSDLELTDLLAEASIVVIRILGGYRA---WQSGIDTVIAGGVP 73 Query: 95 LIVLSGTGEPDAELAAASTAAPDVQQQALAYFNGGGSVNLAQLLRCLSDRLLLSGYGYEP 154 +++SG DAEL ST A QA Y GG NL +L L D +L++G+G+ P Sbjct: 74 AVLVSGEQAADAELTDRSTVAAGTALQAHIYLAHGGVDNLRELHAFLCDTVLMTGFGFTP 133 Query: 155 AQALPEHGLYHPDLEQDARLDDWLALRAQAPAGKPAVGIIFYRAHWLSGNTAFIDALVAA 214 A P G+ R A P + +++YRA L+GNT +++AL A Sbjct: 134 PVATPTWGVLE---------------RPDAGKTGPTIAVLYYRAQHLAGNTGYVEALCRA 178 Query: 215 LEARGMDVLPVFTSSLRVSASSGAALPPALAYFAEGRVDLIINTTSFAMGEITAGGITPA 274 +E G LP++ +SLR A P L G D ++ T + AGG+ PA Sbjct: 179 IEDAGGRPLPLYCASLRT------AEPRLLERL--GGADAMVVTV------LAAGGVKPA 224 Query: 275 G---------WSVSVLEQLNRPVLQAITSGMTQDQWQHSTRGMNPLDAAMNVVLPEFDGR 325 W+V L L+ P+LQ + +DQW + G++PLD A V +PEFDGR Sbjct: 225 AASAGGDDDSWNVEHLAALDIPILQGLCLTSPRDQWCANDDGLSPLDVASQVAVPEFDGR 284 Query: 326 IIGVPLSFKHTSEAGVVQYQALPDRVRRIAGLAQRLVRLRRTPNAEKRIAFIFTNSSSKA 385 II VP SFK + G++ Y A P+R R+AGLA R RLR+ A+KR+A +F+ +K Sbjct: 285 IITVPFSFKEIDDDGLISYVADPERCARVAGLAVRHARLRQVAPADKRVALVFSAYPTKH 344 Query: 386 AQIGNAVGLDAPESLMAVLRALAADGYAIGDLP----DTGTALIHELVDRCSYDDILLTE 441 A+IGNAVGLD P S +A+L+A+ GY +GDLP + G ALIH L++ +D LTE Sbjct: 345 ARIGNAVGLDTPASAVALLQAMRQRGYRVGDLPGVESNDGDALIHALIECGGHDPDWLTE 404 Query: 442 DQLRRAAARIPAARYAQWFAALPAALQARMQRQWGAAPGEAYVHDQH-----LVIAGLDL 496 QL R+ A Y WFA LPA L + WG PGE +V H +VIA L Sbjct: 405 GQLAGNPIRVSAKEYRDWFATLPAELTDVVTAYWGPPPGELFVDRSHDPDGEIVIAALRA 464 Query: 497 GNAFVALQPPRGYGMDPDAIYHQPDLPPTHHYYALYRWLD----EEWGADAIVHVGKHGT 552 GN + +QPPRG+G +P AIYH PDLPP+HHY A YRWLD +GA A+VH+GKHG Sbjct: 465 GNLVLMVQPPRGFGENPVAIYHDPDLPPSHHYLAAYRWLDTGFSNGFGAHAVVHLGKHGN 524 Query: 553 LEWLPGKGVGLSEECFPDALLGDVPLFYPFIINDPGEGSQAKRRAHAVVVDHLTPPMTTA 612 LEWLPGK +G+S C PDA LGD+PL YPF++NDPGEG+QAKRRAHAV+VDHL PPM A Sbjct: 525 LEWLPGKTLGMSASCGPDAALGDLPLIYPFLVNDPGEGTQAKRRAHAVLVDHLIPPMARA 584 Query: 613 DSYGALAQLTQLVDEYYQVEVLDPAKLPLLQQQIWELVRQTNLDTDLQYKLLHHDHDHDH 672 ++YG +A+L QL+DE+ V LDP KLP ++QQIW L+R +D Sbjct: 585 ETYGDIARLEQLLDEHASVAALDPGKLPAIRQQIWTLIRAAKMD---------------- 628 Query: 673 DHEHGHDHGHHHHHHGHHHHDDHHHHHDHDHAHDDGALPHALSELDGAGVAHLIEDLDGY 732 HD + + DD ++ +DG+ Sbjct: 629 -------------------HDLGLTERPEEDSFDD-----------------MLLHVDGW 652 Query: 733 LCELGAAQIRDGLHILGRMPDAQQLPDMLVALTRLPN-----QDLPGLQEEVARLFGLSL 787 LCE+ QIRDGLHILG+ P +Q D+++A+ R +PGL++ GL+ Sbjct: 653 LCEIKDVQIRDGLHILGQNPTGEQELDLVLAILRARQLFGGAHAIPGLRQA----LGLAE 708 Query: 788 DMLLEHKGRRLNIDDALSRTAGRAIVTRADALEAIDALCLSLMQALQHQGFAVPAIEGVI 847 D E R +D T A A E L+ ALQ G+ A Sbjct: 709 DGTDE----RATVDQ-----------TEAKARE--------LVAALQATGWDPSA----- 740 Query: 848 QTLFAPLFXAIKATDTGAVRRILSFACEQLVPRLQRTDEEISNLLNGLRGGYIPAGPSGS 907 A + T +L FA +++PRL T EI +L L G +IPAGPSGS Sbjct: 741 ---------ADRLTGNADAAAVLRFAATEVIPRLAGTATEIEQVLRALDGRFIPAGPSGS 791 Query: 908 PTRGMAHILPTGRNFYSVDPRSVPSQSAWRVGQQLAREVLERHHRESGDYPESVAISIWG 967 P RG+ ++LPTGRNFYSVDP++VPS+ AW G LA +L R+ E G +P SV +S+WG Sbjct: 792 PLRGLVNVLPTGRNFYSVDPKAVPSRLAWEAGVALADSLLARYRDEHGRWPRSVGLSVWG 851 Query: 968 TSAMRTHGDDVAQILSLMGAQPVWREGNRQVAGVELIPLD--QLQRPRIDVTTRISGFFR 1025 TSAMRT GDD+A++L+L+G +PVW + +R+V ++L P+ +L RPRIDVT RISGFFR Sbjct: 852 TSAMRTAGDDIAEVLALLGVRPVWDDASRRV--IDLAPMQPAELGRPRIDVTVRISGFFR 909 Query: 1026 DAFPQLIELIDDAVQLAIAADEPEDMNFVRKHYLRDLQQAMQGGLGQAEAAAQASYRVFG 1085 DAFP ++ ++DDAV+L DE + N+VR H Q L +A+ R+FG Sbjct: 910 DAFPHVVTMLDDAVRLVADLDEAAEDNYVRAH--------AQADLAHHGDQRRATTRIFG 961 Query: 1086 AKPGSYGAGILPLIQEKNWQDQADFAEAYINWGGYAYGRXRDLKE---ETLRVFRARVVN 1142 +KPG+YGAG+L LI ++W+D AD A+ Y WGG+AYGR D +E + R +R V Sbjct: 962 SKPGTYGAGLLQLIDSRSWRDDADLAQVYTAWGGFAYGRDLDGREAIDDMNRQYRRIAVA 1021 Query: 1143 PKWLASIRRHG---------YKGGLELTATVDYLFGYDATAQVMED-------------- 1179 K R H Y GG + ATV L G A + ++ Sbjct: 1022 AK-NTDTREHDIADSDDYFQYHGG--MVATVRALTGQAPAAYIGDNTRPDAIRTRTLSEE 1078 Query: 1180 -------------WM-------YQ---QLAET----YGFDPA-------MREFLEQ---- 1201 WM Y+ ++A T +G+D M E L Q Sbjct: 1079 TTRVFRARVVNPRWMAAMRRHGYKGAFEMAATVDYLFGYDATAGVMADWMYEQLTQRYVL 1138 Query: 1202 ----------ANPWAQNAIAERLLEAASRGMWQTPAVQTIEQLRSLYLHSEALLEA 1247 +NPWA + +AERLLEAA RG+W PA +T++ LR + L +E LEA Sbjct: 1139 DAQNRTFMTESNPWALHGMAERLLEAAGRGLWAQPAPETLDGLRQVLLETEGDLEA 1194 >MT2121 [H] COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases MtC Mycobacterium tuberculosis CDC1551 Length = 1195 Score = 780 bits (2015), Expect = 0.0, Method: Compositional matrix adjust. Identities = 507/1316 (38%), Positives = 691/1316 (52%), Gaps = 242/1316 (18%) Query: 36 LQALQSGTDEQ-GQPLRTLATLLRTELASAQVIVLRVLGRLGAVAGFPELLRAARAEGRQ 94 + A SG + + P R L LA A ++V+R+LG A + + A G Sbjct: 18 ISARSSGKNYRWANPSRLSDLELTDLLAEASIVVIRILGGYRA---WQSGIDTVIAGGVP 74 Query: 95 LIVLSGTGEPDAELAAASTAAPDVQQQALAYFNGGGSVNLAQLLRCLSDRLLLSGYGYEP 154 +++SG DAEL ST A QA Y GG NL +L L D +L++G+G+ P Sbjct: 75 AVLVSGEQAADAELTDRSTVAAGTALQAHIYLAHGGVDNLRELHAFLCDTVLMTGFGFTP 134 Query: 155 AQALPEHGLYHPDLEQDARLDDWLALRAQAPAGKPAVGIIFYRAHWLSGNTAFIDALVAA 214 A P G+ R A P + +++YRA L+GNT +++AL A Sbjct: 135 PVATPTWGVLE---------------RPDAGKTGPTIAVLYYRAQHLAGNTGYVEALCRA 179 Query: 215 LEARGMDVLPVFTSSLRVSASSGAALPPALAYFAEGRVDLIINTTSFAMGEITAGGITPA 274 +E G LP++ +SLR A P L G D ++ T + AGG+ PA Sbjct: 180 IEDAGGRPLPLYCASLRT------AEPRLLERL--GGADAMVVTV------LAAGGVKPA 225 Query: 275 G---------WSVSVLEQLNRPVLQAITSGMTQDQWQHSTRGMNPLDAAMNVVLPEFDGR 325 W+V L L+ P+LQ + +DQW + G++PLD A V +PEFDGR Sbjct: 226 AASAGGDDDSWNVEHLAALDIPILQGLCLTSPRDQWCANDDGLSPLDVASQVAVPEFDGR 285 Query: 326 IIGVPLSFKHTSEAGVVQYQALPDRVRRIAGLAQRLVRLRRTPNAEKRIAFIFTNSSSKA 385 II VP SFK + G++ Y A P+R R+AGLA R RLR+ A+KR+A +F+ +K Sbjct: 286 IITVPFSFKEIDDDGLISYVADPERCARVAGLAVRHARLRQVAPADKRVALVFSAYPTKH 345 Query: 386 AQIGNAVGLDAPESLMAVLRALAADGYAIGDLP----DTGTALIHELVDRCSYDDILLTE 441 A+IGNAVGLD P S +A+L+A+ GY +GDLP + G ALIH L++ +D LTE Sbjct: 346 ARIGNAVGLDTPASAVALLQAMRQRGYRVGDLPGVESNDGDALIHALIECGGHDPDWLTE 405 Query: 442 DQLRRAAARIPAARYAQWFAALPAALQARMQRQWGAAPGEAYVHDQH-----LVIAGLDL 496 QL R+ A Y WFA LPA L + WG PGE +V H +VIA L Sbjct: 406 GQLAGNPIRVSAKEYRDWFATLPAELTDVVTAYWGPPPGELFVDRSHDPDGEIVIAALRA 465 Query: 497 GNAFVALQPPRGYGMDPDAIYHQPDLPPTHHYYALYRWLD----EEWGADAIVHVGKHGT 552 GN + +QPPRG+G +P AIYH PDLPP+HHY A YRWLD +GA A+VH+GKHG Sbjct: 466 GNLVLMVQPPRGFGENPVAIYHDPDLPPSHHYLAAYRWLDTGFSNGFGAHAVVHLGKHGN 525 Query: 553 LEWLPGKGVGLSEECFPDALLGDVPLFYPFIINDPGEGSQAKRRAHAVVVDHLTPPMTTA 612 LEWLPGK +G+S C PDA LGD+PL YPF++NDPGEG+QAKRRAHAV+VDHL PPM A Sbjct: 526 LEWLPGKTLGMSASCGPDAALGDLPLIYPFLVNDPGEGTQAKRRAHAVLVDHLIPPMARA 585 Query: 613 DSYGALAQLTQLVDEYYQVEVLDPAKLPLLQQQIWELVRQTNLDTDLQYKLLHHDHDHDH 672 ++YG +A+L QL+DE+ V LDP KLP ++QQIW L+R +D Sbjct: 586 ETYGDIARLEQLLDEHASVAALDPGKLPAIRQQIWTLIRAAKMD---------------- 629 Query: 673 DHEHGHDHGHHHHHHGHHHHDDHHHHHDHDHAHDDGALPHALSELDGAGVAHLIEDLDGY 732 HD + + DD ++ +DG+ Sbjct: 630 -------------------HDLGLTERPEEDSFDD-----------------MLLHVDGW 653 Query: 733 LCELGAAQIRDGLHILGRMPDAQQLPDMLVALTRLPN-----QDLPGLQEEVARLFGLSL 787 LCE+ QIRDGLHILG+ P +Q D+++A+ R +PGL++ GL+ Sbjct: 654 LCEIKDVQIRDGLHILGQNPTGEQELDLVLAILRARQLFGGAHAIPGLRQA----LGLAE 709 Query: 788 DMLLEHKGRRLNIDDALSRTAGRAIVTRADALEAIDALCLSLMQALQHQGFAVPAIEGVI 847 D E R +D T A A E L+ ALQ G+ A Sbjct: 710 DGTDE----RATVDQ-----------TEAKARE--------LVAALQATGWDPSA----- 741 Query: 848 QTLFAPLFXAIKATDTGAVRRILSFACEQLVPRLQRTDEEISNLLNGLRGGYIPAGPSGS 907 A + T +L FA +++PRL T EI +L L G +IPAGPSGS Sbjct: 742 ---------ADRLTGNADAAAVLRFAATEVIPRLAGTATEIEQVLRALDGRFIPAGPSGS 792 Query: 908 PTRGMAHILPTGRNFYSVDPRSVPSQSAWRVGQQLAREVLERHHRESGDYPESVAISIWG 967 P RG+ ++LPTGRNFYSVDP++VPS+ AW G LA +L R+ E G +P SV +S+WG Sbjct: 793 PLRGLVNVLPTGRNFYSVDPKAVPSRLAWEAGVALADSLLARYRDEHGRWPRSVGLSVWG 852 Query: 968 TSAMRTHGDDVAQILSLMGAQPVWREGNRQVAGVELIPLD--QLQRPRIDVTTRISGFFR 1025 TSAMRT GDD+A++L+L+G +PVW + +R+V ++L P+ +L RPRIDVT RISGFFR Sbjct: 853 TSAMRTAGDDIAEVLALLGVRPVWDDASRRV--IDLAPMQPAELGRPRIDVTVRISGFFR 910 Query: 1026 DAFPQLIELIDDAVQLAIAADEPEDMNFVRKHYLRDLQQAMQGGLGQAEAAAQASYRVFG 1085 DAFP ++ ++DDAV+L DE + N+VR H Q L +A+ R+FG Sbjct: 911 DAFPHVVTMLDDAVRLVADLDEAAEDNYVRAH--------AQADLAHHGDQRRATTRIFG 962 Query: 1086 AKPGSYGAGILPLIQEKNWQDQADFAEAYINWGGYAYGRXRDLKE---ETLRVFRARVVN 1142 +KPG+YGAG+L LI ++W+D AD A+ Y WGG+AYGR D +E + R +R V Sbjct: 963 SKPGTYGAGLLQLIDSRSWRDDADLAQVYTAWGGFAYGRDLDGREAIDDMNRQYRRIAVA 1022 Query: 1143 PKWLASIRRHG---------YKGGLELTATVDYLFGYDATAQVMED-------------- 1179 K R H Y GG + ATV L G A + ++ Sbjct: 1023 AK-NTDTREHDIADSDDYFQYHGG--MVATVRALTGQAPAAYIGDNTRPDAIRTRTLSEE 1079 Query: 1180 -------------WM-------YQ---QLAET----YGFDPA-------MREFLEQ---- 1201 WM Y+ ++A T +G+D M E L Q Sbjct: 1080 TTRVFRARVVNPRWMAAMRRHGYKGAFEMAATVDYLFGYDATAGVMADWMYEQLTQRYVL 1139 Query: 1202 ----------ANPWAQNAIAERLLEAASRGMWQTPAVQTIEQLRSLYLHSEALLEA 1247 +NPWA + +AERLLEAA RG+W PA +T++ LR + L +E LEA Sbjct: 1140 DAQNRTFMTESNPWALHGMAERLLEAAGRGLWAQPAPETLDGLRQVLLETEGDLEA 1195 >alr1689 [H] COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases Nos Nostoc sp. PCC 7120 Length = 1302 Score = 773 bits (1995), Expect = 0.0, Method: Compositional matrix adjust. Identities = 452/1143 (39%), Positives = 633/1143 (55%), Gaps = 87/1143 (7%) Query: 2 ARIVLLTHAPTDLALLAAARAQLPAEFPAVAGYDLQALQSGTDEQGQPLRTLATLLRTEL 61 A VL+T A TD+ LAAA +LPA FPA+ +L LQ ++ T L Sbjct: 25 APFVLITAADTDIQTLAAAVPKLPATFPAIRVANLLLLQQQI--------SIDTYAEQVL 76 Query: 62 ASAQVIVLRVLG-RLGAVAGFPELLRAARAEGRQLIVLSGTGEPDAELAAASTAAPDVQQ 120 AQVI+LR+LG R G + G LIV+ G D EL + STA Sbjct: 77 ELAQVIILRLLGGRSYWAYGLEVVQEIVERTGITLIVMPGDDALDPELISQSTAPVGTVN 136 Query: 121 QALAYFNGGGSVNLAQLLRCLSDRLLLSGYGYEPAQALPEHGLYHPDLEQDARLDDWLAL 180 Q YF GG N+ L+ +SD L + Y Q +P GLY + + + D + Sbjct: 137 QIWQYFYEGGVENIVNALQLISDVSLKTTYKPPAPQRVPRVGLYEWGMGTNRQGDKGNEV 196 Query: 181 RAQAPAGK---PAVGIIFYRAHWLSGNTAFIDALVAALEARGMDVLPVFTSSLRVSASSG 237 + + P VGI+FYRAH+L+GN IDAL AAL R + +PVF SSLR Sbjct: 197 EFSPTSSQSLIPKVGILFYRAHYLAGNIQVIDALCAALWQRNLQPVPVFISSLR-DPDVQ 255 Query: 238 AALPPALAYFAEGRVDLIINTTSFAMGEITAGGITPAGWSVSVLEQLNRPVLQAITSGMT 297 A L ++ L++NTTSF++ + W E+L+ PVLQ I SG Sbjct: 256 AELIDFFQPKDSQQISLLLNTTSFSLARLETEAPQTELW-----EKLDVPVLQVILSGGF 310 Query: 298 QDQWQHSTRGMNPLDAAMNVVLPEFDGRIIGVPLSFKHTS------EAGVVQYQALPDRV 351 +QW+ G++P D AMNV LPE DGRII +SFK E VV Y+ + DR+ Sbjct: 311 VEQWEAQLNGLSPRDIAMNVALPEVDGRIISRAVSFKAIQTRNPDLETDVVVYEPISDRI 370 Query: 352 RRIAGLAQRLVRLRRTPNAEKRIAFIFTNSSSKAAQIGNAVGLDAPESLMAVLRALAADG 411 +A LA V LR P ++RIA I N ++ ++ N VGLD PES + +L+AL G Sbjct: 371 DFVAQLAANWVHLRSQPPQQRRIALILANYPNRDGRLANGVGLDTPESCVEILKALQQSG 430 Query: 412 YAIGDLPDTGTALIHELVDRCSYDDILLTEDQLRRAAARIPAARYAQWFAALPAALQ--- 468 Y + +LP G LI L + D ++R + + Y ++FA LPA +Q Sbjct: 431 YVVSNLPANGDELIQLLTAGVTNDP---EGREIRPVQQSLSSEEYQEYFAGLPATVQQGI 487 Query: 469 -ARMQRQWGAAPGEAYVHDQHLVIAGLDLGNAFVALQPPRGYGMDPDAIYHQPDLPPTHH 527 R R WG + I G+ GN FV +QP RGY +DP+ YH PDL PTH Sbjct: 488 NERWGRDWGLGEQASNFPSSSCPIPGIQFGNVFVGIQPSRGYDIDPNLNYHAPDLEPTHA 547 Query: 528 YYALYRWLDEEWGADAIVHVGKHGTLEWLPGKGVGLSEECFPDALLGDVPLFYPFIINDP 587 Y A Y W+ E +GADA+VHVGKHG LEWLPGK + LS C+P+A+ G +P YPFI+NDP Sbjct: 548 YLAFYYWVRESFGADAVVHVGKHGNLEWLPGKSLALSSNCYPEAVFGPMPHLYPFIVNDP 607 Query: 588 GEGSQAKRRAHAVVVDHLTPPMTTADSYGALAQLTQLVDEYYQVEVLDPAKLPLLQQQIW 647 GEGSQAKRRA AV++DHLTPPMT A+ YGAL +L LVDEYY+ E LDP++L +++ +I Sbjct: 608 GEGSQAKRRAQAVIIDHLTPPMTRAELYGALQKLENLVDEYYEAESLDPSRLGVIRDRIR 667 Query: 648 ELVRQTNLDTDLQYKLLHHDHDHDHDHEHGHDHGHHHHHHGHHHHDDHHHHHDHDHAHDD 707 +LV Q NL YK L + + D + Sbjct: 668 DLVIQENL-----YKDLGIEKEEDIVNFE------------------------------- 691 Query: 708 GALPHALSELDGAGVAHLIEDLDGYLCELGAAQIRDGLHILGRMPDAQQLPDMLVALTRL 767 + ++ LDGYLCEL AQIRDGLHI G+ P +QL D++VA+ R+ Sbjct: 692 ---------------SLILNSLDGYLCELKEAQIRDGLHIFGQCPQGRQLRDLIVAIARI 736 Query: 768 PNQDLPGLQEEVARLFGLSLDMLLEHKGRRLNIDDA--LSRTAGRAIVTRADALEAIDAL 825 PN+ G+ +A ++GL D L ++ L+ D L+ T DA+ A++ Sbjct: 737 PNRYSTGITRALANVWGLDFDPLTDNFSTPLSTQDQKLLAAKTPNPCRTVGDAVTALEEH 796 Query: 826 CLSLMQALQHQGFAVPAI--EGVIQTLFAPLFXAIKATDTGAVRRILSFACEQLVPRLQR 883 L++ L + A P + EG F+ ++ + +L++ +L+P LQ+ Sbjct: 797 AALLVEQLINPPTA-PEVRPEGNPPCDFSSCPLPSSSSPPAPLNTVLNWIKSKLLPSLQQ 855 Query: 884 TDEEISNLLNGLRGGYIPAGPSGSPTRGMAHILPTGRNFYSVDPRSVPSQSAWRVGQQLA 943 T EI+NLL+GL GGYIP+ SG+PTRG +LPTGRNFY+VD R++P+++AW +G++ A Sbjct: 856 THAEITNLLHGLDGGYIPSAASGAPTRGRPEVLPTGRNFYAVDIRAIPTETAWDIGRKAA 915 Query: 944 REVLERHHRESGDYPESVAISIWGTSAMRTHGDDVAQILSLMGAQPVWREGNRQVAGVEL 1003 ++E + +E G+YP+++ +S+WGT+ MRT GDD+A+ L+L+G QPVW R+V +++ Sbjct: 916 ENLVECYTQEHGEYPKTLGLSVWGTATMRTGGDDIAEALALLGVQPVWDGAARRVVDLDI 975 Query: 1004 IPLDQLQRPRIDVTTRISGFFRDAFPQLIELIDDAVQLAIAADEPEDMNFVRKHYLRDLQ 1063 +PL L RPR+DVT RISGFFRDAFP L++L + AV A DEP + N + +D Sbjct: 976 LPLSILGRPRVDVTLRISGFFRDAFPNLMDLFEQAVNAVAALDEPPEQNPLAAQIRQDTD 1035 Query: 1064 QAMQGGLGQAEAAAQASYRVFGAKPGSYGAGILPLIQEKNWQDQADFAEAYINWGGYAYG 1123 +Q GL A ++ YR+FG+KPG+YGAG+ LI+ +NWQ+ D A AYINW YAY Sbjct: 1036 FWIQQGLTPETAFERSRYRLFGSKPGAYGAGLQGLIESQNWQNDQDLANAYINWSCYAYS 1095 Query: 1124 RXR 1126 + Sbjct: 1096 SGK 1098 Score = 143 bits (360), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 64/125 (51%), Positives = 88/125 (70%) Query: 1124 RXRDLKEETLRVFRARVVNPKWLASIRRHGYKGGLELTATVDYLFGYDATAQVMEDWMYQ 1183 R R L+EE RV+R+RVVNPKW+ + RHGYKG E+ ATVD+LF YDAT + +ED+MYQ Sbjct: 1178 RVRQLREEIARVYRSRVVNPKWIEGMMRHGYKGAFEMAATVDFLFAYDATTRCVEDYMYQ 1237 Query: 1184 QLAETYGFDPAMREFLEQANPWAQNAIAERLLEAASRGMWQTPAVQTIEQLRSLYLHSEA 1243 + + Y DP + ++E NP A IAERLLEA RG+W+ ++T+E LR+L +EA Sbjct: 1238 GVMQAYLLDPVVCTYIENKNPHALRDIAERLLEANQRGLWENVNIETLENLRNLVHQAEA 1297 Query: 1244 LLEAR 1248 +EA+ Sbjct: 1298 TIEAK 1302 >slr1211 [H] COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases Syn Synechocystis Length = 1092 Score = 703 bits (1815), Expect = 0.0, Method: Compositional matrix adjust. Identities = 414/1148 (36%), Positives = 605/1148 (52%), Gaps = 167/1148 (14%) Query: 190 AVGIIFYRAHWLSGNTAFIDALVAALEARGMDVLPVFTSSLRVSASSGAALPPALAYFAE 249 + IIFYR+H+LSGNT IDAL ALE ++ L ++ SSLR L A+ + Sbjct: 9 TIAIIFYRSHYLSGNTTPIDALCQALEKHNLNPLAIYVSSLREPDVQAEIL--AILENLD 66 Query: 250 GRVDLIINTTSFAMGEIT--AGGITPAGWSVSVLEQLNRPVLQAITSGMTQDQWQHSTRG 307 + I+NTTSF++ ++ G + + + ++LN PVLQ I SG + QWQ RG Sbjct: 67 QPLGAILNTTSFSLAKLQRQIGNLE----MIPLWQKLNVPVLQVILSGGDRQQWQEGLRG 122 Query: 308 MNPLDAAMNVVLPEFDGRIIGVPLSFKHTS------EAGVVQYQALPDRVRRIAGLAQRL 361 +NP D AMNV LPE DGRII +SFK + E V Y+ + DRV IA L + + Sbjct: 123 LNPRDLAMNVALPEVDGRIITRAISFKAMAARHPQLETEVAIYEPVLDRVEWIAELTKNI 182 Query: 362 VRLRRTPNAEKRIAFIFTNSSSKAAQIGNAVGLDAPESLMAVLRALAADGYAIGDLPDTG 421 + +T +++IA I N +K ++ N VGLD P S + +L AL GY + +P Sbjct: 183 INCAQTEIFQRKIALILANYPNKDGRLANGVGLDTPASCLQILEALKIAGYHLSAIPKDT 242 Query: 422 TALIHELVDRCSYDDILLTEDQLRRAAARIPAARYAQWFAALPAALQARMQRQWGAAPGE 481 LI +L + D L Q R I + Q+F +LP ++Q M +W Sbjct: 243 ETLIKQLTQGVTNDQELA---QYRTVNQTIVTEKVWQFFYSLPQSVQQAMTERWQVRENW 299 Query: 482 AYVHDQHLVIAGLDLGNAFVALQPPRGYGMDPDAIYHQPDLPPTHHYYALYRWLDEEWGA 541 + DQ I+G+ GN FV +QP RGY DP YH PDL PT HY A Y WL +E+ A Sbjct: 300 DNLPDQ-FAISGIQFGNIFVGIQPARGYDFDPSLNYHAPDLEPTLHYLAFYLWLRQEFSA 358 Query: 542 DAIVHVGKHGTLEWLPGKGVGLSEECFPDALLGDVPLFYPFIINDPGEGSQAKRRAHAVV 601 AI+H+GKHG LEWLPGK V LS+ C P+ LG +P FYPFI+NDPGEG+QAKRR+ A + Sbjct: 359 QAIIHLGKHGNLEWLPGKSVVLSDHCHPEIALGPLPNFYPFIVNDPGEGTQAKRRSQACI 418 Query: 602 VDHLTPPMTTADSYGALAQLTQLVDEYYQVEVLDPAKLPLLQQQIWELVRQTNLDTDLQY 661 +DHLTPP+T A+ YG L +L L+DEYY+ + LDP ++ + ++ +L+ +NL TDL Sbjct: 419 IDHLTPPLTRAELYGDLEKLEALIDEYYEAQALDPTRVKTIGDRLRKLLATSNLQTDL-- 476 Query: 662 KLLHHDHDHDHDHEHGHDHGHHHHHHGHHHHDDHHHHHDHDHAHDDGALPHALSELDGAG 721 G P AL +L Sbjct: 477 ----------------------------------------------GLTPPALKDLQP-- 488 Query: 722 VAHLIEDLDGYLCELGAAQIRDGLHILGRMPDAQQLPDMLVALTRLPNQDLPGLQEEVAR 781 L+ D YLCEL AQIRDGLHILG+ P +QL D+ +++ R P+ GL + +A Sbjct: 489 ---LLTSADSYLCELKEAQIRDGLHILGQTPTGEQLRDLAISIARSPSYQRLGLTQAIAF 545 Query: 782 LFGLSLDMLLEHKGRRLNIDDALSRTAGRAIVTRADALEAIDALCLSLMQALQHQGFAVP 841 L D +L+ + + + +T+ + L + + G + Sbjct: 546 DLELEFDPVLDDPNEPWQLSSTMQMKLQQWELTQ----------FIELFNSCRIGGQVIE 595 Query: 842 AIEGVIQTLFAPLFXAIKATDT---------GAVRRILSFACEQLVPRLQRTDEEISNLL 892 +E + + L L + + L + + L+P LQ+T +EI+NLL Sbjct: 596 ILEEIAKQLVGSLLEIVIVDQKVNLFFQKPDSKTKSNLDYIEQTLLPMLQQTPQEITNLL 655 Query: 893 NGLRGGYIPAGPSGSPTRGMAHILPTGRNFYSVDPRSVPSQSAWRVGQQLAREVLERHHR 952 GL G YI +GP+G+P+RG +LPTGRNFY+VD R++P+++AW +G++ A ++ER+ + Sbjct: 656 RGLNGEYIASGPAGAPSRGRPDVLPTGRNFYAVDIRAIPTETAWDIGRRAAETLIERYTQ 715 Query: 953 ESGDYPESVAISIWGTSAMRTHGDDVAQILSLMGAQPVWREGNRQVAGVELIPLDQLQRP 1012 + G+YP+++AISIWGTS MRT GDD+AQ+L+L+G QPVW +R++ E++P L+RP Sbjct: 716 DHGEYPQTLAISIWGTSTMRTGGDDIAQVLALLGVQPVWDSPSRRIVDFEILPTTVLKRP 775 Query: 1013 RIDVTTRISGFFRDAFPQLIELIDDAVQLAIAADEPEDMNFVRKHYLRDLQQAMQGGLGQ 1072 R+DVT RISGFFRD+FP L+E + A+ DEP ++N + + ++ +Q Q GL Sbjct: 776 RVDVTIRISGFFRDSFPNLVEFLHQAIAAVSQLDEPANLNPLAEKVKQETEQWQQLGLAT 835 Query: 1073 AEAAAQASYRVFGAKPGSYGAGILPLIQEKNWQDQADFAEAYINWGGYAYGRXRDLKEET 1132 EA +A+YR+FG+KPG+YGAG+ LI+ +NWQD +D A AY+NW YAY R + + Sbjct: 836 EEAVTKATYRIFGSKPGAYGAGLQGLIEAQNWQDDSDLARAYLNWSCYAYDR-QGVGHNQ 894 Query: 1133 LRVFRARVVNPK------------WLASIRRHGYKGGLELTATVDYLFGYDAT------- 1173 VF R+ N + L S + ++GG LTA V L G + T Sbjct: 895 PEVFAQRLQNLQIVLHNQDNREHDLLDSDDYYQFQGG--LTAAVRSLTGKNPTVYFGDNS 952 Query: 1174 --AQVMEDWMYQQLAETY----------------GFDPAM-------------------- 1195 AQ + Q++A+ Y G+ A Sbjct: 953 NPAQPKVKLLTQEIAKVYRSRVVNPKWIAGVMRHGYKGAFEMAATLDYLFAYDATAHCVE 1012 Query: 1196 -----------------REFLEQANPWAQNAIAERLLEAASRGMWQTPAVQTIEQLRSLY 1238 ++F++Q NPWA +AERLLEA R +W Q ++QLR++ Sbjct: 1013 DFMYTGIAQAYLLDEEVQKFVQQHNPWALRDMAERLLEAEQRQLWSNVDPQLLDQLRAIA 1072 Query: 1239 LHSEALLE 1246 +E +LE Sbjct: 1073 HGAEEILE 1080