BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0028.0362.p (494 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value mll1728 [GEPR] COG0477 Permeases of the major facilitator superf... 411 e-114 mll8348 [GEPR] COG0477 Permeases of the major facilitator superf... 357 5e-98 SMc00813 [GEPR] COG0477 Permeases of the major facilitator super... 344 3e-94 SMc02343 [GEPR] COG0477 Permeases of the major facilitator super... 343 7e-94 AGc1103 [GEPR] COG0477 Permeases of the major facilitator superf... 340 4e-93 >mll1728 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 477 Score = 411 bits (1056), Expect = e-114, Method: Compositional matrix adjust. Identities = 220/470 (46%), Positives = 318/470 (67%), Gaps = 9/470 (1%) Query: 19 SLPDA--RVRMLPYIVAATFFMEYLDTTIIATALPQMAQSFGVGPNELSLGMTAYMLTLA 76 +LP+ R + IVA FFM+ LD+TII+T+LPQM QS+GV +S+G+T YMLT+A Sbjct: 9 ALPETATNARRVALIVAIAFFMQLLDSTIISTSLPQMGQSYGVPAVAMSVGITVYMLTMA 68 Query: 77 VFIPISGWVADRFGSRTVFGIAIAIFTLASVLCGYSQNVWEFTAARVLQGLGGAMMVPVG 136 VF+P+SGW+ADRFG+R +F +AIA+FTLAS+ CG+SQN+ +F AAR +QGLG A+M PVG Sbjct: 69 VFVPLSGWLADRFGARNIFLVAIALFTLASLACGFSQNLTQFVAARAVQGLGSALMTPVG 128 Query: 137 RMIVVRSTGKDRLMKAIATITWPAIVAPVVGPSIGGFITTYASWHWIFLMNVPFGFAAFI 196 R++V+R+ K L+ A A ITWPA+ APVVGP +GGFITT SWHW F +N+P G Sbjct: 129 RILVLRNASKSELLNATALITWPALFAPVVGPVLGGFITTTLSWHWNFFINIPLGLIGLA 188 Query: 197 AVMRVVRNEHGHSKRPLDVIGFLLSGAALTSLLYGTEIASHMESNIKVAAGFVALGVVLG 256 V R + + + +PLD GF L+ L LLYG E +H E + +A G+V+G Sbjct: 189 LVARFIPGDRVANPKPLDWPGFFLTSLGLACLLYGLERIAHPEDGMLPTVLLIAAGIVIG 248 Query: 257 YCAWRHMQRIEHPLLDFSNLRIPTYSVTVL-TGSLTRIGVDAVPYLMPLMFQIGFGLTAF 315 + A RH++R HPLLD S+ ++ T++++ L G++ R+ ++A P+L+PL+FQ+GFGL+ Sbjct: 249 WLAVRHLRRAPHPLLDLSSFKVLTFAISTLAAGTIFRVAINATPFLLPLLFQLGFGLSPV 308 Query: 316 QSGLLLLATALGNLGMKAFTTRILQRFGFRSVAVNNAAIAGCLIIACGLLTPGTPLPVIL 375 +GL++LA +GNLGMK TT L+RFGFRSV V N IA I+ACG+++P TP +++ Sbjct: 309 DAGLMILAYFVGNLGMKTVTTPTLRRFGFRSVMVVNGIIASASIMACGVISPQTPQALVV 368 Query: 376 GVIFCYGLSRSMQFSTLATLAYADISDARKSSASTLWSVAQQMTIGMGIAFGALALRIAA 435 ++ GLSRSMQF+ L TLA+ADI AR+SSA+TL S+ QQ+ + G+A A L ++ Sbjct: 369 VLMLIAGLSRSMQFTALNTLAFADIDAARRSSAATLSSMLQQVAMLFGVAVAAAILNLSQ 428 Query: 436 AIRGEEIDATGAHFTLGDFQWAFAMAGVVTLISVIGYRGLARDAGSNIGG 485 R + L DF+ AF + G + L++ + + L R AG+ + G Sbjct: 429 IARAQP------SLDLVDFRIAFFVIGAIGLVAALRFLVLPRAAGAEVSG 472 >mll8348 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 473 Score = 357 bits (915), Expect = 5e-98, Method: Compositional matrix adjust. Identities = 198/470 (42%), Positives = 286/470 (60%), Gaps = 11/470 (2%) Query: 26 RMLPYIVAATFFMEYLDTTIIATALPQMAQSFGVGPNELSLGMTAYMLTLAVFIPISGWV 85 R +P I+A FME +D+T+IAT+LP +A P L L +TAY+++LA+FIPISGW+ Sbjct: 3 RTIPLILAVALFMENMDSTVIATSLPAIAIDIHTSPIALKLALTAYLVSLAIFIPISGWM 62 Query: 86 ADRFGSRTVFGIAIAIFTLASVLCGYSQNVWEFTAARVLQGLGGAMMVPVGRMIVVRSTG 145 ADRFG++ +F AIA+F + SV C S ++ F +R LQG+GGAMM PVGR+++VR+T Sbjct: 63 ADRFGAKNIFRAAIAVFIVGSVACALSGSLPAFVVSRFLQGIGGAMMTPVGRLVLVRATP 122 Query: 146 KDRLMKAIATITWPAIVAPVVGPSIGGFITTYASWHWIFLMNVPFGFAAFIAVMRVVRNE 205 K L+ A++ +T PA+V P+VGP IGGFITTY +WHWIFL+NVP G R + Sbjct: 123 KSDLVAAMSWLTVPALVGPLVGPPIGGFITTYFTWHWIFLINVPIGLVGIWLATRFLPET 182 Query: 206 HGHSKRPLDVIGFLLSGAALTSLLYGTEIASHMESNIKVAAGFVALGVVL--GYCAWRHM 263 PLD IGF+LSG A + +++G + S + A GF+ +GV L G H Sbjct: 183 ESMETPPLDFIGFVLSGLAASGVVFGLSVVSL--PYLPPATGFITVGVGLLSGALYLMHA 240 Query: 264 QRIEHPLLDFSNLRIPTYSVTVLTGSLTRIGVDAVPYLMPLMFQIGFGLTAFQSGLLLLA 323 +R ++PLL R + +VL GSL RIG+ AVP+L+PLMFQIGFGLT FQSG++ Sbjct: 241 RRAKNPLLALELFRNQVFRSSVLGGSLFRIGIGAVPFLLPLMFQIGFGLTPFQSGMITFV 300 Query: 324 TALGNLGMKAFTTRILQRFGFRSVAVNNAAIAGCLIIACGLLTPGTPLPVILGVIFCYGL 383 +A+G +GMK T I + GFR V + + +A I GL TP TP ++L ++ G Sbjct: 301 SAVGAIGMKFVTALIFRVAGFRRVLIIGSLVAAASIAIYGLFTPETPYVLMLAILLVGGF 360 Query: 384 SRSMQFSTLATLAYADISDARKSSASTLWSVAQQMTIGMGIAFGALALRIAAAIRGEEID 443 RSM F+ + L+YA++S S A+ + +V QQ++I +G+A L ++ +I G + Sbjct: 361 IRSMFFTGVNALSYAEVSAEDTSKATPITAVFQQLSIALGVALAGGILEVSTSIHGGPL- 419 Query: 444 ATGAHFTLGDFQWAFAMAGVVTLISVIGYRGLARDAGSNIGGGMRAAQSK 493 LGDF AF + V+ + + + LA DAG+ + G R K Sbjct: 420 ------MLGDFHIAFFIVAAVSAAASLSFMRLAPDAGNAVSGHGRLTTPK 463 >SMc00813 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 470 Score = 344 bits (882), Expect = 3e-94, Method: Compositional matrix adjust. Identities = 180/460 (39%), Positives = 273/460 (59%), Gaps = 7/460 (1%) Query: 26 RMLPYIVAATFFMEYLDTTIIATALPQMAQSFGVGPNELSLGMTAYMLTLAVFIPISGWV 85 R++P I+A FME +D+T+I+T+LP +A+ GVGP L L +T+YM+ LA+FIP+SGW+ Sbjct: 3 RIVPLILAVALFMEQMDSTVISTSLPAIARDMGVGPITLKLALTSYMVALAIFIPLSGWM 62 Query: 86 ADRFGSRTVFGIAIAIFTLASVLCGYSQNVWEFTAARVLQGLGGAMMVPVGRMIVVRSTG 145 ADRFG++ +F AI +F SV C + +++ F AR LQG+GGAMM PV R+++VRS Sbjct: 63 ADRFGAKRIFRAAILVFIAGSVFCAVADSLFAFVVARFLQGMGGAMMTPVARLVLVRSAP 122 Query: 146 KDRLMKAIATITWPAIVAPVVGPSIGGFITTYASWHWIFLMNVPFGFAAFIAVMRVVRNE 205 + L+ A+A +T PA+V P+ GP +GGFITTY SWHWIFL+NVP G + + Sbjct: 123 RSELVSAMALLTIPALVGPLAGPPLGGFITTYFSWHWIFLINVPVGIVGYFLSGIYLPEM 182 Query: 206 HGHSKRPLDVIGFLLSGAALTSLLYGTEIASHMESNIKVAAGFVALGVVLGYCAWRHMQR 265 + P+D+IGFLL G A +++G + S + V+ GV H +R Sbjct: 183 ERRNPPPVDIIGFLLGGIAAAGVVFGLSVISLPALPPAIGIASVSAGVAASLLYIFHARR 242 Query: 266 IEHPLLDFSNLRIPTYSVTVLTGSLTRIGVDAVPYLMPLMFQIGFGLTAFQSGLLLLATA 325 P+LD R + + G++ RI V AVP+LMPLM Q+GFGL+ FQSGL+ A Sbjct: 243 HPAPVLDLKLFRDGAFRAASIGGTIFRISVGAVPFLMPLMLQVGFGLSPFQSGLITFVGA 302 Query: 326 LGNLGMKAFTTRILQRFGFRSVAVNNAAIAGCLIIACGLLTPGTPLPVILGVIFCYGLSR 385 +G + K R+ GFR+ + A IA A G TP TP +++ V+ G +R Sbjct: 303 VGAITTKFLARRVFAFAGFRTTLLIAAVIAAVTTFANGFFTPATPYLLLISVLLIAGFAR 362 Query: 386 SMQFSTLATLAYADISDARKSSASTLWSVAQQMTIGMGIAFGALALRIAAAIRGEEIDAT 445 S F+ + L++ADI DA S A+++ +V QQ+++ +G+A +A AI E + Sbjct: 363 SFFFTGVNALSFADIDDADASKATSMSAVLQQISLALGVA-------VAGAILEFETALS 415 Query: 446 GAHFTLGDFQWAFAMAGVVTLISVIGYRGLARDAGSNIGG 485 G L DF AF + + L++ I + +A++AG+++ G Sbjct: 416 GKPLELADFHVAFMIIAIANLLAAIPFIAMAKNAGASVSG 455 >SMc02343 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 479 Score = 343 bits (879), Expect = 7e-94, Method: Compositional matrix adjust. Identities = 205/478 (42%), Positives = 302/478 (63%), Gaps = 13/478 (2%) Query: 15 INDTSLPDARVRMLPYIVAATFFMEYLDTTIIATALPQMAQSFGVGPNELSLGMTAYMLT 74 I + LP R R++P +VA FFM+ LD+TIIAT+LP MA SF L++G TAY+L Sbjct: 10 IPSSPLPLHRTRIVPAVVAVAFFMQMLDSTIIATSLPAMAHSFDTDVVALNIGFTAYLLA 69 Query: 75 LAVFIPISGWVADRFGSRTVFGIAIAIFTLASVLCGYSQNVWEFTAARVLQGLGGAMMVP 134 +AVFI +GW+ADRFG+R VF +I +FTL+SV CG+S ++ +FT AR+ QG A+M P Sbjct: 70 MAVFIAPAGWLADRFGAREVFLTSIVLFTLSSVACGFSGSLLQFTVARLFQGASAALMTP 129 Query: 135 VGRMIVVRSTGKDRLMKAIATITWPAIVAPVVGPSIGGFITTYASWHWIFLMNVPFGFAA 194 VGR +V+R K L++AIATITWPA++APV+GP IG +ITT++ W W F +N+P G Sbjct: 130 VGRQLVLRGAPKGELVRAIATITWPALIAPVIGPLIGAWITTHSGWQWNFFINLPLGVLG 189 Query: 195 FIAVMRVVRNEHGHSKRPLDVIGFLLSGAALTSLLYGTEIASHMESNIKVAAG---FVAL 251 + V V G RP D++GFLL+G AL L G E+ S+ V G +A Sbjct: 190 VVLVASFVPRVPGEGARPFDLVGFLLTGGALALTLAGLEL-----SSASVGPGPLTILAS 244 Query: 252 GVVLGYCAWRHMQRIEHPLLDFSNLRIPTYSVTVLT-GSLTRIGVDAVPYLMPLMFQIGF 310 GV+ G A RH+QR + LLD + L++PT++ L+ G+ R+ V+A P+L+PL+FQ+G Sbjct: 245 GVLTGCFAIRHLQRTPNALLDMAVLKVPTFAFATLSAGTAGRLAVNATPFLLPLLFQLGL 304 Query: 311 GLTAFQSGLLLLATALGNLGMKAFTTRILQRFGFRSVAVNNAAIAGCLIIACGLLTPGTP 370 G A ++G L+LA LGNL MK+ TT L+ FGFRS+ V N IA I A + TP Sbjct: 305 GFDAVETGSLVLAYFLGNLLMKSVTTPALRLFGFRSLLVVNGVIAALTIGAFAFVDGETP 364 Query: 371 LPVILGVIFCYGLSRSMQFSTLATLAYADISDARKSSASTLWSVAQQMTIGMGIAFGALA 430 ++ ++ GLSRSMQF++L T+A+AD++ A++S+A+T+ ++ QQ+ +G+A A Sbjct: 365 HMLLFALLVACGLSRSMQFTSLTTIAFADVTPAQRSAATTISAMLQQLAQLLGVAVAASI 424 Query: 431 LRIAAAIRGEEIDATGAHFTLGDFQWAFAMAGVVTLISVIGYRGLARDAGSNIGGGMR 488 +R+++ +R + D L D + AF + L S + + L DAG ++ G R Sbjct: 425 IRLSSYLRPDGADGG----MLTDIRAAFLCIAAIGLASALRFLALPHDAGVDVSGHRR 478 >AGc1103 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 475 Score = 340 bits (873), Expect = 4e-93, Method: Compositional matrix adjust. Identities = 178/460 (38%), Positives = 275/460 (59%), Gaps = 7/460 (1%) Query: 26 RMLPYIVAATFFMEYLDTTIIATALPQMAQSFGVGPNELSLGMTAYMLTLAVFIPISGWV 85 R++P I+A FME +D+T+IAT+LP +A+ VGP L L +TAYM+ LA+FIPISGW+ Sbjct: 13 RIIPLILAVALFMEQMDSTVIATSLPAIAKDLHVGPITLKLALTAYMVALAIFIPISGWM 72 Query: 86 ADRFGSRTVFGIAIAIFTLASVLCGYSQNVWEFTAARVLQGLGGAMMVPVGRMIVVRSTG 145 AD++G++ +F IAI +F + S+ C S +V+EF +R LQG+GGAMM PVGR++++R+T Sbjct: 73 ADKYGAKKIFRIAIGVFVVGSICCAVSSSVFEFVLSRFLQGMGGAMMTPVGRLVLLRTTK 132 Query: 146 KDRLMKAIATITWPAIVAPVVGPSIGGFITTYASWHWIFLMNVPFGFAAFIAVMRVVRNE 205 + L+ A+A +T P +V P+ GP IGGFITTY SWHWIFL+NVP G + Sbjct: 133 RSELVSAMALLTIPGLVGPLTGPPIGGFITTYFSWHWIFLINVPIGIIGIWLSTIFLPEI 192 Query: 206 HGHSKRPLDVIGFLLSGAALTSLLYGTEIASHMESNIKVAAGFVALGVVLGYCAWRHMQR 265 + P+D GF+LSG A + +++G + S + +G + G+ RH R Sbjct: 193 ETTNPPPMDGKGFILSGIAASGVVFGVSVVSLPALPPAIGIASTVIGFICGFLYMRHAAR 252 Query: 266 IEHPLLDFSNLRIPTYSVTVLTGSLTRIGVDAVPYLMPLMFQIGFGLTAFQSGLLLLATA 325 P+LDF + T+ + G++ RI A+P+LMPLM QIGFGL FQSG++ A A Sbjct: 253 HPAPILDFRIFQNATFRAASVGGTVFRISTGAIPFLMPLMLQIGFGLNPFQSGMITFAGA 312 Query: 326 LGNLGMKAFTTRILQRFGFRSVAVNNAAIAGCLIIACGLLTPGTPLPVILGVIFCYGLSR 385 +G + K R+ GFRS + + +A TP TP P+I+ + G +R Sbjct: 313 IGAITTKFMAKRVFAATGFRSTLIGAGIVGAFTTLANSFFTPETPYPLIMIFLVTAGFAR 372 Query: 386 SMQFSTLATLAYADISDARKSSASTLWSVAQQMTIGMGIAFGALALRIAAAIRGEEIDAT 445 S F+ L+Y+DI D++ S A+++ SV QQ+++ +G+AF A L +++ + + Sbjct: 373 SFFFTGSNALSYSDIEDSQASQATSMASVLQQISLALGVAFAASILEVSSMM-------S 425 Query: 446 GAHFTLGDFQWAFAMAGVVTLISVIGYRGLARDAGSNIGG 485 G H L DF AF + +V+L +++ + AG+ + G Sbjct: 426 GTHLQLADFHIAFTIVALVSLFAIVPIIRMDAQAGAAVSG 465