BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0028.0342.p (460 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value SMc00813 [GEPR] COG0477 Permeases of the major facilitator super... 416 e-116 mll8348 [GEPR] COG0477 Permeases of the major facilitator superf... 410 e-114 AGc1103 [GEPR] COG0477 Permeases of the major facilitator superf... 400 e-111 BMEII0596 [GEPR] COG0477 Permeases of the major facilitator supe... 374 e-103 mll1728 [GEPR] COG0477 Permeases of the major facilitator superf... 312 1e-84 >SMc00813 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 470 Score = 416 bits (1068), Expect = e-116, Method: Compositional matrix adjust. Identities = 211/453 (46%), Positives = 313/453 (69%), Gaps = 3/453 (0%) Query: 6 LIPLIVGCALFMENMDATVLATSLPALARDLHQDPITLKLAMTAYVAALGVFIPISGWMA 65 ++PLI+ ALFME MD+TV++TSLPA+ARD+ PITLKLA+T+Y+ AL +FIP+SGWMA Sbjct: 4 IVPLILAVALFMEQMDSTVISTSLPAIARDMGVGPITLKLALTSYMVALAIFIPLSGWMA 63 Query: 66 DKLGARKVFSWAMIVFMTGSILCAVSGSLVTFVAARFLQGIGGAMMVPVGRVIIARSVDK 125 D+ GA+++F A++VF+ GS+ CAV+ SL FV ARFLQG+GGAMM PV R+++ RS + Sbjct: 64 DRFGAKRIFRAAILVFIAGSVFCAVADSLFAFVVARFLQGMGGAMMTPVARLVLVRSAPR 123 Query: 126 SELVKAVSYLTLPALLGPVVGPLLGGFLTTYFHWRWVFLINIPFCFLGLYLAKRFIQNFK 185 SELV A++ LT+PAL+GP+ GP LGGF+TTYF W W+FLIN+P +G +L+ ++ + Sbjct: 124 SELVSAMALLTIPALVGPLAGPPLGGFITTYFSWHWIFLINVPVGIVGYFLSGIYLPEME 183 Query: 186 EDNPAPLDVKGFVLTSVGAAMIMLGLSLFGSQLVDGATPVAMCSIGAIALVMYYRHSTQI 245 NP P+D+ GF+L + AA ++ GLS+ + A +A S G A ++Y H+ + Sbjct: 184 RRNPPPVDIIGFLLGGIAAAGVVFGLSVISLPALPPAIGIASVSAGVAASLLYIFHARRH 243 Query: 246 PYPLLDFRLLRIPTLHASVVGGSLFRIGLGAVPFLLPLALQEGLGMTAFQAGSITCASAF 305 P P+LD +L R A+ +GG++FRI +GAVPFL+PL LQ G G++ FQ+G IT A Sbjct: 244 PAPVLDLKLFRDGAFRAASIGGTIFRISVGAVPFLMPLMLQVGFGLSPFQSGLITFVGAV 303 Query: 306 GSLFIRLLASRVLRRYGFRTVLMVNAVFAGIALAAYGIFSMHTPYLLIVTIVLMGGVFPA 365 G++ + LA RV GFRT L++ AV A + A G F+ TPYLL+++++L+ G + Sbjct: 304 GAITTKFLARRVFAFAGFRTTLLIAAVIAAVTTFANGFFTPATPYLLLISVLLIAGFARS 363 Query: 366 LQFTCLNSIAYADIDSRDAGRVTSLASVIQQLSLGLGVTVAGIVLQLSNHLQGHASIVEA 425 FT +N++++ADID DA + TS+++V+QQ+SL LGV VAG +L+ L G + A Sbjct: 364 FFFTGVNALSFADIDDADASKATSMSAVLQQISLALGVAVAGAILEFETALSGK-PLELA 422 Query: 426 DFWPAFLVIGLFS-VASVPISGKLPHNAGLELS 457 DF AF++I + + +A++P + NAG +S Sbjct: 423 DFHVAFMIIAIANLLAAIPFIA-MAKNAGASVS 454 >mll8348 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 473 Score = 410 bits (1053), Expect = e-114, Method: Compositional matrix adjust. Identities = 205/427 (48%), Positives = 300/427 (70%), Gaps = 1/427 (0%) Query: 7 IPLIVGCALFMENMDATVLATSLPALARDLHQDPITLKLAMTAYVAALGVFIPISGWMAD 66 IPLI+ ALFMENMD+TV+ATSLPA+A D+H PI LKLA+TAY+ +L +FIPISGWMAD Sbjct: 5 IPLILAVALFMENMDSTVIATSLPAIAIDIHTSPIALKLALTAYLVSLAIFIPISGWMAD 64 Query: 67 KLGARKVFSWAMIVFMTGSILCAVSGSLVTFVAARFLQGIGGAMMVPVGRVIIARSVDKS 126 + GA+ +F A+ VF+ GS+ CA+SGSL FV +RFLQGIGGAMM PVGR+++ R+ KS Sbjct: 65 RFGAKNIFRAAIAVFIVGSVACALSGSLPAFVVSRFLQGIGGAMMTPVGRLVLVRATPKS 124 Query: 127 ELVKAVSYLTLPALLGPVVGPLLGGFLTTYFHWRWVFLINIPFCFLGLYLAKRFIQNFKE 186 +LV A+S+LT+PAL+GP+VGP +GGF+TTYF W W+FLIN+P +G++LA RF+ + Sbjct: 125 DLVAAMSWLTVPALVGPLVGPPIGGFITTYFTWHWIFLINVPIGLVGIWLATRFLPETES 184 Query: 187 DNPAPLDVKGFVLTSVGAAMIMLGLSLFGSQLVDGATPVAMCSIGAIALVMYYRHSTQIP 246 PLD GFVL+ + A+ ++ GLS+ + AT +G ++ +Y H+ + Sbjct: 185 METPPLDFIGFVLSGLAASGVVFGLSVVSLPYLPPATGFITVGVGLLSGALYLMHARRAK 244 Query: 247 YPLLDFRLLRIPTLHASVVGGSLFRIGLGAVPFLLPLALQEGLGMTAFQAGSITCASAFG 306 PLL L R +SV+GGSLFRIG+GAVPFLLPL Q G G+T FQ+G IT SA G Sbjct: 245 NPLLALELFRNQVFRSSVLGGSLFRIGIGAVPFLLPLMFQIGFGLTPFQSGMITFVSAVG 304 Query: 307 SLFIRLLASRVLRRYGFRTVLMVNAVFAGIALAAYGIFSMHTPYLLIVTIVLMGGVFPAL 366 ++ ++ + + + R GFR VL++ ++ A ++A YG+F+ TPY+L++ I+L+GG ++ Sbjct: 305 AIGMKFVTALIFRVAGFRRVLIIGSLVAAASIAIYGLFTPETPYVLMLAILLVGGFIRSM 364 Query: 367 QFTCLNSIAYADIDSRDAGRVTSLASVIQQLSLGLGVTVAGIVLQLSNHLQGHASIVEAD 426 FT +N+++YA++ + D + T + +V QQLS+ LGV +AG +L++S + G ++ D Sbjct: 365 FFTGVNALSYAEVSAEDTSKATPITAVFQQLSIALGVALAGGILEVSTSIHG-GPLMLGD 423 Query: 427 FWPAFLV 433 F AF + Sbjct: 424 FHIAFFI 430 >AGc1103 [GEPR] COG0477 Permeases of the major facilitator superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 475 Score = 400 bits (1029), Expect = e-111, Method: Compositional matrix adjust. Identities = 215/458 (46%), Positives = 308/458 (67%), Gaps = 5/458 (1%) Query: 6 LIPLIVGCALFMENMDATVLATSLPALARDLHQDPITLKLAMTAYVAALGVFIPISGWMA 65 +IPLI+ ALFME MD+TV+ATSLPA+A+DLH PITLKLA+TAY+ AL +FIPISGWMA Sbjct: 14 IIPLILAVALFMEQMDSTVIATSLPAIAKDLHVGPITLKLALTAYMVALAIFIPISGWMA 73 Query: 66 DKLGARKVFSWAMIVFMTGSILCAVSGSLVTFVAARFLQGIGGAMMVPVGRVIIARSVDK 125 DK GA+K+F A+ VF+ GSI CAVS S+ FV +RFLQG+GGAMM PVGR+++ R+ + Sbjct: 74 DKYGAKKIFRIAIGVFVVGSICCAVSSSVFEFVLSRFLQGMGGAMMTPVGRLVLLRTTKR 133 Query: 126 SELVKAVSYLTLPALLGPVVGPLLGGFLTTYFHWRWVFLINIPFCFLGLYLAKRFIQNFK 185 SELV A++ LT+P L+GP+ GP +GGF+TTYF W W+FLIN+P +G++L+ F+ + Sbjct: 134 SELVSAMALLTIPGLVGPLTGPPIGGFITTYFSWHWIFLINVPIGIIGIWLSTIFLPEIE 193 Query: 186 EDNPAPLDVKGFVLTSVGAAMIMLGLSLFGSQLVDGATPVAMCSIGAIALVMYYRHSTQI 245 NP P+D KGF+L+ + A+ ++ G+S+ + A +A IG I +Y RH+ + Sbjct: 194 TTNPPPMDGKGFILSGIAASGVVFGVSVVSLPALPPAIGIASTVIGFICGFLYMRHAARH 253 Query: 246 PYPLLDFRLLRIPTLHASVVGGSLFRIGLGAVPFLLPLALQEGLGMTAFQAGSITCASAF 305 P P+LDFR+ + T A+ VGG++FRI GA+PFL+PL LQ G G+ FQ+G IT A A Sbjct: 254 PAPILDFRIFQNATFRAASVGGTVFRISTGAIPFLMPLMLQIGFGLNPFQSGMITFAGAI 313 Query: 306 GSLFIRLLASRVLRRYGFRTVLMVNAVFAGIALAAYGIFSMHTPYLLIVTIVLMGGVFPA 365 G++ + +A RV GFR+ L+ + A F+ TPY LI+ ++ G + Sbjct: 314 GAITTKFMAKRVFAATGFRSTLIGAGIVGAFTTLANSFFTPETPYPLIMIFLVTAGFARS 373 Query: 366 LQFTCLNSIAYADIDSRDAGRVTSLASVIQQLSLGLGVTVAGIVLQLSNHLQGHASIVEA 425 FT N+++Y+DI+ A + TS+ASV+QQ+SL LGV A +L++S+ + G + A Sbjct: 374 FFFTGSNALSYSDIEDSQASQATSMASVLQQISLALGVAFAASILEVSSMMSG-THLQLA 432 Query: 426 DFWPAFLVIGLFSV-ASVPISGKLPHNAGLELS--RGK 460 DF AF ++ L S+ A VPI ++ AG +S RGK Sbjct: 433 DFHIAFTIVALVSLFAIVPII-RMDAQAGAAVSGHRGK 469 >BMEII0596 [GEPR] COG0477 Permeases of the major facilitator superfamily Bme Brucella melitensis Length = 469 Score = 374 bits (961), Expect = e-103, Method: Compositional matrix adjust. Identities = 197/452 (43%), Positives = 294/452 (65%), Gaps = 1/452 (0%) Query: 6 LIPLIVGCALFMENMDATVLATSLPALARDLHQDPITLKLAMTAYVAALGVFIPISGWMA 65 +IPL++ ALFME MD+ V++TSLPA+A D+ PI LKLA+TAY+ AL VFIP+SGWMA Sbjct: 4 IIPLVLAIALFMEQMDSNVISTSLPAIAADIGTSPIALKLALTAYLVALAVFIPVSGWMA 63 Query: 66 DKLGARKVFSWAMIVFMTGSILCAVSGSLVTFVAARFLQGIGGAMMVPVGRVIIARSVDK 125 D+ GA+ VF A+ VF+ GSI CA S SL FV ARFLQG+GGAMM PVGR+++ RS + Sbjct: 64 DRFGAKNVFRAAIAVFVVGSIACAASNSLPAFVIARFLQGMGGAMMTPVGRLVLIRSTPR 123 Query: 126 SELVKAVSYLTLPALLGPVVGPLLGGFLTTYFHWRWVFLINIPFCFLGLYLAKRFIQNFK 185 +ELV A+++LT+PA++GP+VGP +GGF+TT+ W W+FLIN+P +G++ A F+ + + Sbjct: 124 NELVSAMAWLTIPAMVGPLVGPPVGGFITTFLTWHWIFLINVPIGMIGIWFATHFLPDNE 183 Query: 186 EDNPAPLDVKGFVLTSVGAAMIMLGLSLFGSQLVDGATPVAMCSIGAIALVMYYRHSTQI 245 E LD GF L+ + ++ GLS+ + A ++G + V+Y H+ + Sbjct: 184 ERIIKRLDWPGFFLSGFAMSGVVFGLSVVSLPALPPVIGFATLAVGMLCTVLYVLHARRT 243 Query: 246 PYPLLDFRLLRIPTLHASVVGGSLFRIGLGAVPFLLPLALQEGLGMTAFQAGSITCASAF 305 P PLL+ RL ++V GGS+FR G+GA+PFLLPL Q G G+T FQ+G +T SA Sbjct: 244 PDPLLNLRLFDNQVFRSAVFGGSIFRFGIGAIPFLLPLMFQLGFGLTPFQSGMMTFVSAI 303 Query: 306 GSLFIRLLASRVLRRYGFRTVLMVNAVFAGIALAAYGIFSMHTPYLLIVTIVLMGGVFPA 365 G++ ++ A R+ R FR LM ++ + +A G F+ TPY +I+ +L+GG + Sbjct: 304 GAISMKFGAKRIFTRISFRRALMGGSLISAAFIAVNGTFTPATPYWIIIGFLLVGGFARS 363 Query: 366 LQFTCLNSIAYADIDSRDAGRVTSLASVIQQLSLGLGVTVAGIVLQLSNHLQGHASIVEA 425 L FT +N++A+A+I + + T L +V QQ+S+ +GV +AG +L++S L+G A + Sbjct: 364 LFFTGVNALAFAEIPNEKTSQATPLTAVAQQVSIAIGVALAGGILEISTMLRG-APLALV 422 Query: 426 DFWPAFLVIGLFSVASVPISGKLPHNAGLELS 457 DF F V+ SV + +L +AG EL+ Sbjct: 423 DFHIGFFVVACVSVLAFFWFARLAPDAGKELA 454 >mll1728 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 477 Score = 312 bits (799), Expect = 1e-84, Method: Compositional matrix adjust. Identities = 180/453 (39%), Positives = 275/453 (60%), Gaps = 3/453 (0%) Query: 7 IPLIVGCALFMENMDATVLATSLPALARDLHQDPITLKLAMTAYVAALGVFIPISGWMAD 66 + LIV A FM+ +D+T+++TSLP + + + + + +T Y+ + VF+P+SGW+AD Sbjct: 20 VALIVAIAFFMQLLDSTIISTSLPQMGQSYGVPAVAMSVGITVYMLTMAVFVPLSGWLAD 79 Query: 67 KLGARKVFSWAMIVFMTGSILCAVSGSLVTFVAARFLQGIGGAMMVPVGRVIIARSVDKS 126 + GAR +F A+ +F S+ C S +L FVAAR +QG+G A+M PVGR+++ R+ KS Sbjct: 80 RFGARNIFLVAIALFTLASLACGFSQNLTQFVAARAVQGLGSALMTPVGRILVLRNASKS 139 Query: 127 ELVKAVSYLTLPALLGPVVGPLLGGFLTTYFHWRWVFLINIPFCFLGLYLAKRFIQNFKE 186 EL+ A + +T PAL PVVGP+LGGF+TT W W F INIP +GL L RFI + Sbjct: 140 ELLNATALITWPALFAPVVGPVLGGFITTTLSWHWNFFINIPLGLIGLALVARFIPGDRV 199 Query: 187 DNPAPLDVKGFVLTSVGAAMIMLGLSLFGSQLVDGATP-VAMCSIGAIALVMYYRHSTQI 245 NP PLD GF LTS+G A ++ GL + DG P V + + G + + RH + Sbjct: 200 ANPKPLDWPGFFLTSLGLACLLYGLERI-AHPEDGMLPTVLLIAAGIVIGWLAVRHLRRA 258 Query: 246 PYPLLDFRLLRIPTLHASVV-GGSLFRIGLGAVPFLLPLALQEGLGMTAFQAGSITCASA 304 P+PLLD ++ T S + G++FR+ + A PFLLPL Q G G++ AG + A Sbjct: 259 PHPLLDLSSFKVLTFAISTLAAGTIFRVAINATPFLLPLLFQLGFGLSPVDAGLMILAYF 318 Query: 305 FGSLFIRLLASRVLRRYGFRTVLMVNAVFAGIALAAYGIFSMHTPYLLIVTIVLMGGVFP 364 G+L ++ + + LRR+GFR+V++VN + A ++ A G+ S TP L+V ++L+ G+ Sbjct: 319 VGNLGMKTVTTPTLRRFGFRSVMVVNGIIASASIMACGVISPQTPQALVVVLMLIAGLSR 378 Query: 365 ALQFTCLNSIAYADIDSRDAGRVTSLASVIQQLSLGLGVTVAGIVLQLSNHLQGHASIVE 424 ++QFT LN++A+ADID+ +L+S++QQ+++ GV VA +L LS + S+ Sbjct: 379 SMQFTALNTLAFADIDAARRSSAATLSSMLQQVAMLFGVAVAAAILNLSQIARAQPSLDL 438 Query: 425 ADFWPAFLVIGLFSVASVPISGKLPHNAGLELS 457 DF AF VIG + + LP AG E+S Sbjct: 439 VDFRIAFFVIGAIGLVAALRFLVLPRAAGAEVS 471