BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0028.0208.p (282 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0987 [GER] COG0697 Permeases of the drug/metabolite transport... 281 1e-75 SMb20040 [GER] COG0697 Permeases of the drug/metabolite transpor... 237 3e-62 AGc394 [GER] COG0697 Permeases of the drug/metabolite transporte... 227 3e-59 BS_ydeK [GER] COG0697 Permeases of the drug/metabolite transport... 226 3e-59 mll1137 [GER] COG0697 Permeases of the drug/metabolite transport... 222 9e-58 >RSc0987 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Rso Ralstonia solanacearum Length = 313 Score = 281 bits (719), Expect = 1e-75, Method: Compositional matrix adjust. Identities = 177/291 (60%), Positives = 206/291 (70%), Gaps = 11/291 (3%) Query: 3 LGLIGVAIFSLTLPFTRIAVAELNPAFVAFGRAVVAGVCALALLAWIKAP----RPTRQQ 58 LG IGV IFS TLPFTR+AVAEL+ FVA AV+A + ALALLA A RP Q Sbjct: 23 LGFIGVTIFSQTLPFTRMAVAELDATFVALAHAVLASLLALALLAATGALRAARRPRGGQ 82 Query: 59 LRGLVITALGVVVGFPLFSSIAMRYVPAAHGAVVVGLLPLATALFGALRFGERPSKGFWL 118 L +TA GVVVGFPLFSS+AMR VPAAHGA++ GLLPLATALF A ERPS FW Sbjct: 83 WGRLAVTAAGVVVGFPLFSSLAMRDVPAAHGAIITGLLPLATALFAAWFGRERPSPWFWA 142 Query: 119 AALAGSGIVIAFALREGGGSFHLADFALFAAVVTAAMGYAEGGRLAQTMGGQNVIAWALV 178 ALAGS +V++FAL G G+ H AD+ LFAA+V A+GYA GG+L++ +GG IAWALV Sbjct: 143 CALAGSVLVVSFALLRGAGTLHRADWLLFAAMVAGALGYAVGGKLSRELGGTQTIAWALV 202 Query: 179 VALPVMLPVSVWLGWQYGV-------TASSPAWLAFAYVSLFSMFIGFFFWYKGLALGGI 231 V+LP +LPV L W G AS AWL AYVS FSMF+GF FWY GLA GG+ Sbjct: 203 VSLPALLPVVGALAWLPGTHQAAALAQASGHAWLGLAYVSAFSMFVGFLFWYSGLAAGGV 262 Query: 232 ARVGQVQLLQPFMSLLGAAVIAHEALDASNMLFALAVIVVVAIGRRMAVRR 282 ARVGQ+QLLQPFM+L+G ++ E LDA MLFALAVI VV +GRR AVRR Sbjct: 263 ARVGQIQLLQPFMTLIGGWLLLGEPLDAPTMLFALAVIAVVGLGRRTAVRR 313 >SMb20040 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Sme Sinorhizobium meliloti Length = 286 Score = 237 bits (604), Expect = 3e-62, Method: Compositional matrix adjust. Identities = 131/276 (47%), Positives = 180/276 (65%) Query: 4 GLIGVAIFSLTLPFTRIAVAELNPAFVAFGRAVVAGVCALALLAWIKAPRPTRQQLRGLV 63 GLIGV IFS +LP TR+AV + +P F+ RA +AG+ A LL + RP R L L Sbjct: 11 GLIGVVIFSGSLPATRVAVMDFDPIFLTVARATIAGILAFCLLFAFRERRPARGDLASLA 70 Query: 64 ITALGVVVGFPLFSSIAMRYVPAAHGAVVVGLLPLATALFGALRFGERPSKGFWLAALAG 123 + +LGVVVGFPL +++A+R+V +AH V +GLLPLATA+FG LR GERP FW+ + G Sbjct: 71 VISLGVVVGFPLMTALALRHVTSAHSIVFIGLLPLATAIFGVLRGGERPRPTFWVFSGLG 130 Query: 124 SGIVIAFALREGGGSFHLADFALFAAVVTAAMGYAEGGRLAQTMGGQNVIAWALVVALPV 183 S IV+ FA R+G + + D + AA+V +GYAEG +L++ +GG VI WALV++LPV Sbjct: 131 SAIVVGFAARQGFSASPIGDLLMLAAIVACGLGYAEGAKLSRRLGGWQVICWALVLSLPV 190 Query: 184 MLPVSVWLGWQYGVTASSPAWLAFAYVSLFSMFIGFFFWYKGLALGGIARVGQVQLLQPF 243 M + + S+ +WL F YVS+FSM IGF FWY+GLALGGI VGQ+QLLQPF Sbjct: 191 MTALMLATMPSSLAGPSAASWLGFGYVSVFSMLIGFIFWYRGLALGGIVAVGQLQLLQPF 250 Query: 244 MSLLGAAVIAHEALDASNMLFALAVIVVVAIGRRMA 279 L A+ + E + S + +A++ VA ++ A Sbjct: 251 FGLALASTLLGENVSWSMLAATVAIVACVAGAKKFA 286 >AGc394 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 291 Score = 227 bits (578), Expect = 3e-59, Method: Compositional matrix adjust. Identities = 136/283 (48%), Positives = 182/283 (64%), Gaps = 5/283 (1%) Query: 2 WL-GLIGVAIFSLTLPFTRIAVAELNPAFVAFGRAVVAGVCALALLAWIKAPRPTRQQLR 60 WL GL GV IFS +LP TR+AV +P F+ RA +AG+ ALALL + RP R L Sbjct: 8 WLNGLTGVVIFSGSLPATRLAVTGFDPVFLTAARASIAGLLALALLFLFRQKRPARGDLT 67 Query: 61 GLVITALGVVVGFPLFSSIAMRYVPAAHGAVVVGLLPLATALFGALRFGERPSKGFWLAA 120 L+I ++GVVVGFPL +++A+R+V +AH + VGLLPLATA+F +R GERP FWL + Sbjct: 68 SLIIVSIGVVVGFPLLTALALRHVTSAHSIIFVGLLPLATAIFAVMRGGERPRPVFWLFS 127 Query: 121 LAGSGIVIAFALREGGGSFHLA----DFALFAAVVTAAMGYAEGGRLAQTMGGQNVIAWA 176 GS +V F+L + A D + A++ +GYAEG L++ +GG VI+WA Sbjct: 128 CLGSALVAGFSLSNSFAARIEASLAGDLLMLGAIIVCGLGYAEGAALSRKLGGWQVISWA 187 Query: 177 LVVALPVMLPVSVWLGWQYGVTASSPAWLAFAYVSLFSMFIGFFFWYKGLALGGIARVGQ 236 LV++LPVMLP++ + G + AW AYVSLFSM IGF FWY+GLALGGIA VGQ Sbjct: 188 LVLSLPVMLPLAFFTGPETLGGIDPQAWGGLAYVSLFSMLIGFIFWYRGLALGGIAAVGQ 247 Query: 237 VQLLQPFMSLLGAAVIAHEALDASNMLFALAVIVVVAIGRRMA 279 +QLLQPF L AA + HE + + + L V++ VA R+ A Sbjct: 248 LQLLQPFFGLALAATLLHEEVSPAMIGVTLVVVLCVAGARKFA 290 >BS_ydeK [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Bsu Bacillus subtilis Length = 287 Score = 226 bits (577), Expect = 3e-59, Method: Compositional matrix adjust. Identities = 139/276 (50%), Positives = 188/276 (68%) Query: 4 GLIGVAIFSLTLPFTRIAVAELNPAFVAFGRAVVAGVCALALLAWIKAPRPTRQQLRGLV 63 G IGV IFS +LP TR+AV++ +P F+ RA +AGV A LL + P ++ L L+ Sbjct: 11 GFIGVLIFSGSLPATRLAVSDFDPLFLTVCRAAIAGVLAGGLLLIFRQQHPAKRDLISLL 70 Query: 64 ITALGVVVGFPLFSSIAMRYVPAAHGAVVVGLLPLATALFGALRFGERPSKGFWLAALAG 123 + A GVV+GFPL +++A+++V +AH V +GLLPLATA+FG LR GERP FW+ + AG Sbjct: 71 VVAFGVVIGFPLLTALALQHVTSAHAIVFIGLLPLATAVFGVLRGGERPRPVFWIFSAAG 130 Query: 124 SGIVIAFALREGGGSFHLADFALFAAVVTAAMGYAEGGRLAQTMGGQNVIAWALVVALPV 183 S +V FAL +GGGS L D + A++V +GYAEG +L++ +G VI+WALV++LP+ Sbjct: 131 SLLVAGFALIQGGGSSPLGDAYMLASIVVCGLGYAEGAKLSRRLGNWQVISWALVLSLPL 190 Query: 184 MLPVSVWLGWQYGVTASSPAWLAFAYVSLFSMFIGFFFWYKGLALGGIARVGQVQLLQPF 243 MLP+S + PA L+ AYVSLFSM IGF FWY+GLA GGIA VGQ+QLLQPF Sbjct: 191 MLPLSFFFTPDSWSAIGVPALLSLAYVSLFSMLIGFVFWYRGLAQGGIAAVGQLQLLQPF 250 Query: 244 MSLLGAAVIAHEALDASNMLFALAVIVVVAIGRRMA 279 LL A+VI HE + + + +AVI+ VA RR A Sbjct: 251 FGLLLASVILHEKVGWALVAVNIAVIMCVAAARRFA 286 >mll1137 [GER] COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily Mlo Mesorhizobium loti Length = 291 Score = 222 bits (565), Expect = 9e-58, Method: Compositional matrix adjust. Identities = 131/276 (47%), Positives = 175/276 (63%) Query: 4 GLIGVAIFSLTLPFTRIAVAELNPAFVAFGRAVVAGVCALALLAWIKAPRPTRQQLRGLV 63 G IGV IFS +LP TR+AV + +P FV RA +AG+ LA+L + RP R L LV Sbjct: 15 GFIGVLIFSGSLPATRVAVMDFDPTFVTSARAAIAGLLGLAMLLLFREKRPDRGDLVSLV 74 Query: 64 ITALGVVVGFPLFSSIAMRYVPAAHGAVVVGLLPLATALFGALRFGERPSKGFWLAALAG 123 I ALGVVVGFPL +++A++++ +AH + +GLLPLATA+FG LR G+RP WL + G Sbjct: 75 IVALGVVVGFPLLTALALKHITSAHSIIFIGLLPLATAIFGVLRGGDRPRPALWLFSCIG 134 Query: 124 SGIVIAFALREGGGSFHLADFALFAAVVTAAMGYAEGGRLAQTMGGQNVIAWALVVALPV 183 S +V FAL +G + + D + AAV+ +GYAEG L++ +GG VI WAL ++LPV Sbjct: 135 SALVAGFALTQGVTASPVGDGLMLAAVIVCGLGYAEGAALSRRLGGWQVICWALTLSLPV 194 Query: 184 MLPVSVWLGWQYGVTASSPAWLAFAYVSLFSMFIGFFFWYKGLALGGIARVGQVQLLQPF 243 ML +S S AW+ YVSLFSM IGF FWY+GLA GGIA VGQ+QLLQPF Sbjct: 195 MLVLSFATLPPSFAAVGSHAWIGLGYVSLFSMLIGFVFWYRGLAQGGIAAVGQLQLLQPF 254 Query: 244 MSLLGAAVIAHEALDASNMLFALAVIVVVAIGRRMA 279 L AA + HE + ++ L V+ V ++ A Sbjct: 255 FGLALAASLLHEQVSPLMVVVTLGVVACVFGAKKFA 290