BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0028.0192.p (915 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value ZyhiH_1 [V] COG1131 ABC-type multidrug transport system, ATPase ... 775 0.0 yhiH_1 [V] COG1131 ABC-type multidrug transport system, ATPase c... 774 0.0 ECs4359_1 [V] COG1131 ABC-type multidrug transport system, ATPas... 769 0.0 STM3586_1 [V] COG1131 ABC-type multidrug transport system, ATPas... 763 0.0 PA5231_1 [V] COG1131 ABC-type multidrug transport system, ATPase... 753 0.0 >ZyhiH_1 [V] COG1131 ABC-type multidrug transport system, ATPase component EcZ Escherichia coli O157:H7 EDL933 Length = 532 Score = 775 bits (2000), Expect = 0.0, Method: Compositional matrix adjust. Identities = 380/539 (70%), Positives = 443/539 (82%), Gaps = 7/539 (1%) Query: 16 VSLRYGQKPALQAISLEIPAGCMVGLIGPDGVGKSSLLSLVAGARALQEGDVEVLGGDMR 75 +S YG+ AL I+L+IPA CMVGLIGPDGVGKSSLLSL++GAR +++G+V VLGGDMR Sbjct: 1 MSQHYGKTVALNNITLDIPARCMVGLIGPDGVGKSSLLSLISGARVIEQGNVIVLGGDMR 60 Query: 76 RAAHREAVCPRIAYMPQGLGKNLYPTLSVEENLQFFGRLFGQSAQERRQRIDTLTAGTGL 135 HR VCPRIA+MPQGLGKNLY TLSV EN+ FF RLFG ER RI+ L TGL Sbjct: 61 DPKHRRDVCPRIAWMPQGLGKNLYHTLSVYENVDFFARLFGHDKAEREVRINELLTSTGL 120 Query: 136 SPFLARPAGKLSGGMKQKLGLCCSLIHDPDLLILDEPTTGVDPLSRAQFWDLIAHIRQQR 195 +PF RPAGKLSGGMKQKLGLCC+LIHDP+LLILDEPTTGVDPLSRAQFWDLI IRQ++ Sbjct: 121 APFRDRPAGKLSGGMKQKLGLCCALIHDPELLILDEPTTGVDPLSRAQFWDLIDSIRQRQ 180 Query: 196 PGMSVIVATAYMEEADRFDFLVAMDDGQILATGTPAELHARTGTAALEEAFIALLPPDKR 255 MSV+VATAYMEEA+RFD+LVAM+ G++LATG+ EL +T +A LEEAFI LLP +R Sbjct: 181 SNMSVLVATAYMEEAERFDWLVAMNAGEVLATGSAEELRQQTQSATLEEAFINLLPQAQR 240 Query: 256 RGHQPVQVIPLDPARQAEIAIEARGLTMRFGDFVAVDHVDFRIRRGEIFGFLGSNGCGKS 315 + HQ V + P P AEIAIEAR LTMRFG FVAVDHV+FRI RGEIFGFLGSNGCGKS Sbjct: 241 QAHQAVVIPPYQP-ENAEIAIEARDLTMRFGSFVAVDHVNFRIPRGEIFGFLGSNGCGKS 299 Query: 316 TTMKMLTGLLPASEGQAWLFGQAVDPRDMATRARVGYMSQAFSLYGELSVRQNLVLHARL 375 TTMKMLTGLLPASEG+AWLFGQ VDP+D+ TR RVGYMSQAFSLY EL+VRQNL LHARL Sbjct: 300 TTMKMLTGLLPASEGEAWLFGQPVDPKDIDTRRRVGYMSQAFSLYNELTVRQNLELHARL 359 Query: 376 YRVPQEQIAARTEEMAQRFGLQEVMDSLPESLPLGIRQRLSLAVAMVHKPELLILDEPTS 435 + +P+ +I AR EM++RF L +V D LPESLPLGIRQRLSLAVA++H+PE+LILDEPTS Sbjct: 360 FHIPEAEIPARVAEMSERFKLNDVEDVLPESLPLGIRQRLSLAVAVIHRPEMLILDEPTS 419 Query: 436 GVDPIARDLFWQLMIDLARRDQVTIFISTHFMNEAQRCDRISLMHAGRVLVSATPEELIR 495 GVDP+ARD+FWQLM+DL+R+D+VTIFISTHFMNEA+RCDRISLMHAG+VL S TP+EL+ Sbjct: 420 GVDPVARDMFWQLMVDLSRQDKVTIFISTHFMNEAERCDRISLMHAGKVLASGTPQELVE 479 Query: 496 QRGSATLEQAFIAYLEEAAGKGAMTPAPEVNVTSARNHAPAGDGRLRTSLGRALSYSQR 554 +RG+A+LE+AFIAYL+EAAG+ AP V HAP R SL R SYS+R Sbjct: 480 KRGAASLEEAFIAYLQEAAGQSNEAEAPP--VIHDTTHAP----RQGFSLRRLFSYSRR 532 >yhiH_1 [V] COG1131 ABC-type multidrug transport system, ATPase component Eco Escherichia coli K12 Length = 532 Score = 774 bits (1999), Expect = 0.0, Method: Compositional matrix adjust. Identities = 379/539 (70%), Positives = 443/539 (82%), Gaps = 7/539 (1%) Query: 16 VSLRYGQKPALQAISLEIPAGCMVGLIGPDGVGKSSLLSLVAGARALQEGDVEVLGGDMR 75 +S YG+ AL I+L+IPA CMVGLIGPDGVGKSSLLSL++GAR +++G+V VLGGDMR Sbjct: 1 MSQHYGKTVALNNITLDIPARCMVGLIGPDGVGKSSLLSLISGARVIEQGNVMVLGGDMR 60 Query: 76 RAAHREAVCPRIAYMPQGLGKNLYPTLSVEENLQFFGRLFGQSAQERRQRIDTLTAGTGL 135 HR VCPRIA+MPQGLGKNLY TLSV EN+ FF RLFG ER RI+ L TGL Sbjct: 61 DPKHRRDVCPRIAWMPQGLGKNLYHTLSVYENVDFFARLFGHDKAEREVRINELLTSTGL 120 Query: 136 SPFLARPAGKLSGGMKQKLGLCCSLIHDPDLLILDEPTTGVDPLSRAQFWDLIAHIRQQR 195 +PF RPAGKLSGGMKQKLGLCC+LIHDP+LLILDEPTTGVDPLSR+QFWDLI IRQ++ Sbjct: 121 APFRDRPAGKLSGGMKQKLGLCCALIHDPELLILDEPTTGVDPLSRSQFWDLIDSIRQRQ 180 Query: 196 PGMSVIVATAYMEEADRFDFLVAMDDGQILATGTPAELHARTGTAALEEAFIALLPPDKR 255 MSV+VATAYMEEA+RFD+LVAM+ G++LATG+ EL +T +A LEEAFI LLP +R Sbjct: 181 SNMSVLVATAYMEEAERFDWLVAMNAGEVLATGSAEELRQQTQSATLEEAFINLLPQAQR 240 Query: 256 RGHQPVQVIPLDPARQAEIAIEARGLTMRFGDFVAVDHVDFRIRRGEIFGFLGSNGCGKS 315 + HQ V + P P AEIAIEAR LTMRFG FVAVDHV+FRI RGEIFGFLGSNGCGKS Sbjct: 241 QAHQAVVIPPYQP-ENAEIAIEARDLTMRFGSFVAVDHVNFRIPRGEIFGFLGSNGCGKS 299 Query: 316 TTMKMLTGLLPASEGQAWLFGQAVDPRDMATRARVGYMSQAFSLYGELSVRQNLVLHARL 375 TTMKMLTGLLPASEG+AWLFGQ VDP+D+ TR RVGYMSQAFSLY EL+VRQNL LHARL Sbjct: 300 TTMKMLTGLLPASEGEAWLFGQPVDPKDIDTRRRVGYMSQAFSLYNELTVRQNLELHARL 359 Query: 376 YRVPQEQIAARTEEMAQRFGLQEVMDSLPESLPLGIRQRLSLAVAMVHKPELLILDEPTS 435 + +P+ +I AR EM++RF L +V D LPESLPLGIRQRLSLAVA++H+PE+LILDEPTS Sbjct: 360 FHIPEAEIPARVAEMSERFKLNDVEDILPESLPLGIRQRLSLAVAVIHRPEMLILDEPTS 419 Query: 436 GVDPIARDLFWQLMIDLARRDQVTIFISTHFMNEAQRCDRISLMHAGRVLVSATPEELIR 495 GVDP+ARD+FWQLM+DL+R+D+VTIFISTHFMNEA+RCDRISLMHAG+VL S TP+EL+ Sbjct: 420 GVDPVARDMFWQLMVDLSRQDKVTIFISTHFMNEAERCDRISLMHAGKVLASGTPQELVE 479 Query: 496 QRGSATLEQAFIAYLEEAAGKGAMTPAPEVNVTSARNHAPAGDGRLRTSLGRALSYSQR 554 +RG+A+LE+AFIAYL+EAAG+ AP V HAP R SL R SYS+R Sbjct: 480 KRGAASLEEAFIAYLQEAAGQSNEAEAPP--VVHDTTHAP----RQGFSLRRLFSYSRR 532 >ECs4359_1 [V] COG1131 ABC-type multidrug transport system, ATPase component Ecs Escherichia coli O157:H7 Length = 516 Score = 769 bits (1985), Expect = 0.0, Method: Compositional matrix adjust. Identities = 369/510 (72%), Positives = 431/510 (84%), Gaps = 1/510 (0%) Query: 16 VSLRYGQKPALQAISLEIPAGCMVGLIGPDGVGKSSLLSLVAGARALQEGDVEVLGGDMR 75 +S YG+ AL I+L+IPA CMVGLIGPDGVGKSSLLSL++GAR +++G+V VLGGDMR Sbjct: 1 MSQHYGKTVALNNITLDIPARCMVGLIGPDGVGKSSLLSLISGARVIEQGNVIVLGGDMR 60 Query: 76 RAAHREAVCPRIAYMPQGLGKNLYPTLSVEENLQFFGRLFGQSAQERRQRIDTLTAGTGL 135 HR VCPRIA+MPQGLGKNLY TLSV EN+ FF RLFG ER RI+ L TGL Sbjct: 61 DPKHRRDVCPRIAWMPQGLGKNLYHTLSVYENVDFFARLFGHDKAEREVRINELLTSTGL 120 Query: 136 SPFLARPAGKLSGGMKQKLGLCCSLIHDPDLLILDEPTTGVDPLSRAQFWDLIAHIRQQR 195 +PF RPAGKLSGGMKQKLGLCC+LIHDP+LLILDEPTTGVDPLSRAQFWDLI IRQ++ Sbjct: 121 APFRDRPAGKLSGGMKQKLGLCCALIHDPELLILDEPTTGVDPLSRAQFWDLIDSIRQRQ 180 Query: 196 PGMSVIVATAYMEEADRFDFLVAMDDGQILATGTPAELHARTGTAALEEAFIALLPPDKR 255 MSV+VATAYMEEA+RFD+LVAM+ G++LATG+ EL +T +A LEEAFI LLP +R Sbjct: 181 SNMSVLVATAYMEEAERFDWLVAMNAGEVLATGSAEELRQQTQSATLEEAFINLLPQAQR 240 Query: 256 RGHQPVQVIPLDPARQAEIAIEARGLTMRFGDFVAVDHVDFRIRRGEIFGFLGSNGCGKS 315 + HQ V + P P AEIAIEAR LTMRFG FVAVDHV+FRI RGEIFGFLGSNGCGKS Sbjct: 241 QAHQAVVIPPYQP-ENAEIAIEARDLTMRFGSFVAVDHVNFRIPRGEIFGFLGSNGCGKS 299 Query: 316 TTMKMLTGLLPASEGQAWLFGQAVDPRDMATRARVGYMSQAFSLYGELSVRQNLVLHARL 375 TTMKMLTGLLPASEG+AWLFGQ VDP+D+ TR RVGYMSQAFSLY EL+VRQNL LHARL Sbjct: 300 TTMKMLTGLLPASEGEAWLFGQPVDPKDIDTRRRVGYMSQAFSLYNELTVRQNLELHARL 359 Query: 376 YRVPQEQIAARTEEMAQRFGLQEVMDSLPESLPLGIRQRLSLAVAMVHKPELLILDEPTS 435 + +P+ +I AR EM++RF L +V D LPESLPLGIRQRLSLAVA++H+PE+LILDEPTS Sbjct: 360 FHIPEAEIPARVAEMSERFKLNDVEDVLPESLPLGIRQRLSLAVAVIHRPEMLILDEPTS 419 Query: 436 GVDPIARDLFWQLMIDLARRDQVTIFISTHFMNEAQRCDRISLMHAGRVLVSATPEELIR 495 GVDP+ARD+FWQLM+DL+R+D+VTIFISTHFMNEA+RCDRISLMHAG+VL S TP+EL+ Sbjct: 420 GVDPVARDMFWQLMVDLSRQDKVTIFISTHFMNEAERCDRISLMHAGKVLASGTPQELVE 479 Query: 496 QRGSATLEQAFIAYLEEAAGKGAMTPAPEV 525 +RG+A+LE+AFIAYL+EAAG+ AP V Sbjct: 480 KRGAASLEEAFIAYLQEAAGQSNEAEAPPV 509 >STM3586_1 [V] COG1131 ABC-type multidrug transport system, ATPase component Sty Salmonella typhimurium LT2 Length = 534 Score = 763 bits (1971), Expect = 0.0, Method: Compositional matrix adjust. Identities = 378/539 (70%), Positives = 443/539 (82%), Gaps = 5/539 (0%) Query: 16 VSLRYGQKPALQAISLEIPAGCMVGLIGPDGVGKSSLLSLVAGARALQEGDVEVLGGDMR 75 +S YG+ AL I+L+IPA MVGLIGPDGVGKSSLLSL++GAR +++G+V VLGGDMR Sbjct: 1 MSQHYGKTVALNNITLDIPARSMVGLIGPDGVGKSSLLSLISGARVIEQGNVIVLGGDMR 60 Query: 76 RAAHREAVCPRIAYMPQGLGKNLYPTLSVEENLQFFGRLFGQSAQERRQRIDTLTAGTGL 135 A HR VCPRIA+MPQGLGKNLY TLSV EN+ FF RLFG ER RI L TGL Sbjct: 61 DAKHRRDVCPRIAWMPQGLGKNLYHTLSVYENVDFFARLFGHDKAEREARITELLNSTGL 120 Query: 136 SPFLARPAGKLSGGMKQKLGLCCSLIHDPDLLILDEPTTGVDPLSRAQFWDLIAHIRQQR 195 +PF RPAGKLSGGMKQKLGLCC+LI+DP+LLILDEPTTGVDPLSRAQFWDLI IRQ++ Sbjct: 121 APFRDRPAGKLSGGMKQKLGLCCALIYDPELLILDEPTTGVDPLSRAQFWDLIDSIRQRQ 180 Query: 196 PGMSVIVATAYMEEADRFDFLVAMDDGQILATGTPAELHARTGTAALEEAFIALLPPDKR 255 MSV+VATAYMEEA+RFD+LVAM+ G+ILATG+ +L A+T +A LE+AFIALLP +R Sbjct: 181 TNMSVLVATAYMEEAERFDWLVAMNAGEILATGSAQQLRAKTHSATLEQAFIALLPEAQR 240 Query: 256 RGHQPVQVIPLDPARQAEIAIEARGLTMRFGDFVAVDHVDFRIRRGEIFGFLGSNGCGKS 315 + H+PV VIP A Q EIAIEA+ LTMRFG FVAVDHV+FRI RGEIFGFLGSNGCGKS Sbjct: 241 QAHKPV-VIPPYHAEQEEIAIEAKDLTMRFGKFVAVDHVNFRIPRGEIFGFLGSNGCGKS 299 Query: 316 TTMKMLTGLLPASEGQAWLFGQAVDPRDMATRARVGYMSQAFSLYGELSVRQNLVLHARL 375 TTMKMLTGLLPASEGQAWLFGQ VDP D+ TR RVGYMSQAFSLY EL+VRQNL LHARL Sbjct: 300 TTMKMLTGLLPASEGQAWLFGQPVDPNDIDTRRRVGYMSQAFSLYNELTVRQNLELHARL 359 Query: 376 YRVPQEQIAARTEEMAQRFGLQEVMDSLPESLPLGIRQRLSLAVAMVHKPELLILDEPTS 435 + +P +I AR +M +RF L EV D+LP SLPLGIRQRLSLAVA++H+PE+LILDEPTS Sbjct: 360 FHIPPAEIPARVAQMIERFMLTEVEDTLPASLPLGIRQRLSLAVAVIHRPEMLILDEPTS 419 Query: 436 GVDPIARDLFWQLMIDLARRDQVTIFISTHFMNEAQRCDRISLMHAGRVLVSATPEELIR 495 GVDP+ARD+FWQLM+DL+R+D+VTIFISTHFMNEA+RCDR+SLMHAG+VL S TP+EL++ Sbjct: 420 GVDPVARDMFWQLMVDLSRQDKVTIFISTHFMNEAERCDRMSLMHAGKVLASGTPQELVQ 479 Query: 496 QRGSATLEQAFIAYLEEAAGKGAMTPAPEVNVTSARNHAPAGDGRLRTSLGRALSYSQR 554 QRG+A LE AFI++L+EAAG TP P + T A + P+ G S R SYS+R Sbjct: 480 QRGAANLEAAFISWLQEAAGAAPETPIPP-SQTPAASGKPSRQG---LSFRRLFSYSRR 534 >PA5231_1 [V] COG1131 ABC-type multidrug transport system, ATPase component Pae Pseudomonas aeruginosa Length = 547 Score = 753 bits (1943), Expect = 0.0, Method: Compositional matrix adjust. Identities = 377/504 (74%), Positives = 416/504 (82%), Gaps = 3/504 (0%) Query: 6 GQSLVARLSGVSLRYGQKPALQAISLEIPAGCMVGLIGPDGVGKSSLLSLVAGARALQEG 65 G S VA L GVSLRYG+ A+ +SLEIPA MVGLIGPDGVGKSSLL+L+AGAR +Q+G Sbjct: 4 GGSGVASLRGVSLRYGETRAVDDVSLEIPANRMVGLIGPDGVGKSSLLALLAGARKMQDG 63 Query: 66 DVEVLGGDMRRAAHREAVCPRIAYMPQGLGKNLYPTLSVEENLQFFGRLFGQSAQERRQR 125 ++ VL GDMR HR AVCPRIAYMPQGLGKNLYPTLSV EN+ FFGRLFG ER +R Sbjct: 64 EIRVLDGDMRDRRHRRAVCPRIAYMPQGLGKNLYPTLSVFENVDFFGRLFGHDKAERERR 123 Query: 126 IDTLTAGTGLSPFLARPAGKLSGGMKQKLGLCCSLIHDPDLLILDEPTTGVDPLSRAQFW 185 I L TGL+PF RPAGKLSGGMKQKLGLCC+LIHDPDLLILDEPTTGVDPLSR QFW Sbjct: 124 IADLLQSTGLAPFAERPAGKLSGGMKQKLGLCCALIHDPDLLILDEPTTGVDPLSRNQFW 183 Query: 186 DLIAHIRQQRPGMSVIVATAYMEEADRFDFLVAMDDGQILATGTPAELHARTGTAALEEA 245 +LI IR R GMSV+VATAYMEEA+RFD+LVAMDDG++LATGTP EL RTGT +LE A Sbjct: 184 ELIGRIRAGREGMSVLVATAYMEEAERFDWLVAMDDGKVLATGTPQELRERTGTQSLESA 243 Query: 246 FIALLPPDKRRGHQPVQVIPLDPARQA--EIAIEARGLTMRFGDFVAVDHVDFRIRRGEI 303 FIALLP KR GH + VIP P + IAIEA GLT RFGDFVAVDHV FRI RGEI Sbjct: 244 FIALLPESKRAGHHRL-VIPPRPQSEGAPRIAIEAEGLTCRFGDFVAVDHVSFRIERGEI 302 Query: 304 FGFLGSNGCGKSTTMKMLTGLLPASEGQAWLFGQAVDPRDMATRARVGYMSQAFSLYGEL 363 FGFLGSNGCGKSTTMKMLTGLLPASEG LFGQ VD DMATR RVGYMSQAFSLY EL Sbjct: 303 FGFLGSNGCGKSTTMKMLTGLLPASEGTCALFGQPVDASDMATRRRVGYMSQAFSLYAEL 362 Query: 364 SVRQNLVLHARLYRVPQEQIAARTEEMAQRFGLQEVMDSLPESLPLGIRQRLSLAVAMVH 423 SVRQNLVLHARL+ +P + I AR EM +RF L++V D LP LPLGIRQRLSLAVA++H Sbjct: 363 SVRQNLVLHARLFHLPADGIPARVGEMLRRFDLEKVADELPNDLPLGIRQRLSLAVAVIH 422 Query: 424 KPELLILDEPTSGVDPIARDLFWQLMIDLARRDQVTIFISTHFMNEAQRCDRISLMHAGR 483 KPE+LILDEPTSGVDP+ARD FW+LM++L+RRD VTIFISTHFMNEAQRCDRISLMHAG+ Sbjct: 423 KPEILILDEPTSGVDPVARDGFWELMVELSRRDGVTIFISTHFMNEAQRCDRISLMHAGK 482 Query: 484 VLVSATPEELIRQRGSATLEQAFI 507 VL S TP+EL+RQRG TLE FI Sbjct: 483 VLASDTPDELVRQRGLPTLEATFI 506