BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0028.0153.p (532 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSp0663 [GEPR] COG0477 Permeases of the major facilitator superf... 678 0.0 BS_yusP [GEPR] COG0477 Permeases of the major facilitator superf... 226 8e-59 DR0258 [GEPR] COG0477 Permeases of the major facilitator superfa... 225 2e-58 DRA0061 [GEPR] COG0477 Permeases of the major facilitator superf... 213 1e-54 DR1327 [GEPR] COG0477 Permeases of the major facilitator superfa... 213 1e-54 >RSp0663 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 537 Score = 678 bits (1749), Expect = 0.0, Method: Compositional matrix adjust. Identities = 353/531 (66%), Positives = 428/531 (80%), Gaps = 3/531 (0%) Query: 1 MALHTDAAHSSGQVLPFRESLLATLGICFVIMLVALDQTIVGTALPTIVAELKGFDLYAW 60 MALHT HS QVLPF+ESLLA LGICFV++LVALDQT+VGTALPT+VAELKGFDLYAW Sbjct: 8 MALHTALPHSHTQVLPFKESLLAMLGICFVVVLVALDQTVVGTALPTVVAELKGFDLYAW 67 Query: 61 VATAYLLTSVITVPIFGRLGDYFGRKPFVIASIVVFVGASALCGMANSMLFLVLARGLQG 120 VAT+YLLTSV+TVP+FGRLGD++GRKPFV+ASIVVF AS +CGMA SM FLV AR LQG Sbjct: 68 VATSYLLTSVVTVPVFGRLGDFYGRKPFVVASIVVFTLASVMCGMAGSMAFLVWARALQG 127 Query: 121 IGGGMLVGTCFASIADLFPDPRVRLRWQIILSASFGIATAVGPSLGGFLTQGLGWRWVFY 180 IGGGMLVGT +A IADLFPD RVRLRWQ++LSASFGIA A+GP+LGG++TQ LGWR VFY Sbjct: 128 IGGGMLVGTAYACIADLFPDARVRLRWQVLLSASFGIANAIGPTLGGWMTQALGWRSVFY 187 Query: 181 CNLPIGVLSLYFVWRFVPHIRHMQHAGKMRLDWPGALLISLSLGSLQLLVELLPKRGITG 240 N+P GVL L+F WRF+PH+R HAG++R DW GALLI+ +LG+LQL VE LP+ G++ Sbjct: 188 VNVPFGVLGLWFAWRFLPHLRQSLHAGRIRPDWQGALLITAALGALQLSVEWLPRHGLSL 247 Query: 241 GMMVLLAVSVAAFYALWRWEQRAAQPILPFEMMRDKALASLFVLSVLAGFAMFSLLMYAP 300 ++ L +S AAF LW WEQRA QP+LPFEM+RD ALA+LFVL+ L+GF+MF+LL YAP Sbjct: 248 PVLGWLVLSAAAFAGLWWWEQRAEQPLLPFEMVRDPALATLFVLAALSGFSMFALLFYAP 307 Query: 301 LLFQGGFGLSPREAGLLITPLVACITVASIVNGRIITRIPNPNLMMNLGFALIAASCLGV 360 LLFQGGFG+SP++AGL+ITPLV CIT+ SI+NGR++TRIP P +M+ GFAL+A + G+ Sbjct: 308 LLFQGGFGMSPQQAGLVITPLVVCITLGSIINGRLVTRIPRPTVMLYAGFALLALALAGM 367 Query: 361 VLCDRTTGNGFLLTVMLAGGFGLGLVLPNLTVFAQQAAAREHLGIATALLQSLRMIGGML 420 R T L +ML G GLG VLPNLTVFAQQ+A R HLGIATALLQSLRM+GGM+ Sbjct: 368 AASSRATPQLALTLLMLLAGLGLGFVLPNLTVFAQQSAGRAHLGIATALLQSLRMVGGMI 427 Query: 421 GTAITGTLVSQMYGAGVQKALEGDHAAQWLKDFSDPEVLVNHDIQSVLLAQLMQAGHDGS 480 GTA+ GTLVS+ Y AGV AL D A QWL+ +DPE+L++H+ Q+ LLAQ+ AGHDG+ Sbjct: 428 GTALVGTLVSERYAAGVGDALRADGATQWLRRLADPEILIDHEAQTALLAQMQSAGHDGA 487 Query: 481 ALLEAAREALVGAIHMGIAIAIVAALAGLWMVRRVPPIRFDQDKKVEPVMS 531 ALL AAR LV AIH+G+ +A V A+ GLW VRRVPP+ VEPV + Sbjct: 488 ALLGAARHVLVSAIHLGLIVAAVVAVVGLWRVRRVPPVAL---YHVEPVQT 535 >BS_yusP [GEPR] COG0477 Permeases of the major facilitator superfamily Bsu Bacillus subtilis Length = 541 Score = 226 bits (577), Expect = 8e-59, Method: Compositional matrix adjust. Identities = 143/435 (32%), Positives = 240/435 (55%), Gaps = 40/435 (9%) Query: 18 RESLLATLGICFVIMLVALDQTIVGTALPTIVAELKGFDLYAWVATAYLLTSVITVPIFG 77 + +LL T G+ + ALD TIVGTA+P IV +L G + W+ TAYLLTS VPI G Sbjct: 11 KRTLLIT-GLIIAMFFSALDGTIVGTAMPKIVGDLGGLSMMTWLTTAYLLTSTTIVPIAG 69 Query: 78 RLGDYFGRKPFVIASIVVFVGASALCGMANSMLFLVLARGLQGIGGGMLVGTCFASIADL 137 +L D GR+ ++ +++F+ ASALCGMAN+M L++ RGLQGIGGG+++ I DL Sbjct: 70 KLADLLGRRIVYVSGLIIFMAASALCGMANNMTELIIFRGLQGIGGGIMMPMAMIVIGDL 129 Query: 138 FPDPRVRLRWQIILSASFGIATAVGPSLGGFLTQGLGWRWVFYCNLPIGVLSLYFVWRFV 197 F + R ++Q + A +G+A+ +GP +GG++ L W+WVFY NLP+G++++ F+ R Sbjct: 130 FTGKQ-RAKFQGVFGAIYGLASVIGPQIGGWIVDSLNWKWVFYINLPVGIIAVIFIAR-- 186 Query: 198 PHIRHMQHAGKMRLDWPG---------ALLISLSLG-------SLQLLVELLPKRGITGG 241 ++ Q G + D G +LL++LS G S Q+L G Sbjct: 187 -GLQGRQQTGPINFDIAGIFTMIVGVVSLLLALSFGGKDYAWDSWQIL-----------G 234 Query: 242 MMVLLAVSVAAFYALWRWEQRAAQPILPFEMMRDKALASLFVLSVLAGFAMFSLLMYAPL 301 + L + + +F + E +A +PILP + +++ L ++ MF + + P Sbjct: 235 LFALALIGIVSFIIV---ESKAKEPILPMYLFKNRTFTFLNLIGFFMSIGMFGAITFVPF 291 Query: 302 LFQGGFGLSPREAGLLITPLVACITVASIVNGRIITRIP-NPNLMMNLGFALIAASCLGV 360 QG G+S E+G ++TP++ + + SI+ G+++ +I P ++ + L+ A + Sbjct: 292 FMQGIVGVSASESGTIMTPMMISMIITSIIGGQLVYKIGIKPQIITGM---LVMAGGFLL 348 Query: 361 VLCDRTTGNGFLLTVMLA-GGFGLGLVLPNLTVFAQQAAAREHLGIATALLQSLRMIGGM 419 + + + T +A G G+GLV+P LT+ Q++ ++E LG+ T+ Q R IGG Sbjct: 349 LTTLDLDTSKLVATSFMAIIGLGMGLVMPILTLALQESFSKEELGVVTSSSQFFRSIGGT 408 Query: 420 LGTAITGTLVSQMYG 434 G + G +++ G Sbjct: 409 FGITMLGAVMNARSG 423 >DR0258 [GEPR] COG0477 Permeases of the major facilitator superfamily Dra Deinococcus radiodurans Length = 544 Score = 225 bits (574), Expect = 2e-58, Method: Compositional matrix adjust. Identities = 171/494 (34%), Positives = 259/494 (52%), Gaps = 18/494 (3%) Query: 13 QVLPFRESLLATLGICFVIMLVALDQTIVGTALPTIVAELKGFDLYAWVATAYLLTSVIT 72 L RE LLA GI V+ L +L+ T+VG+A+P ++++L GF LYAW TAY LT+ +T Sbjct: 13 NTLSEREKLLAFAGILTVLFLSSLNMTVVGSAMPRVISDLGGFHLYAWAFTAYSLTTTVT 72 Query: 73 VPIFGRLGDYFGRKPFVIASIVVFVGASALCGMANSMLFLVLARGLQGIGGGMLVGTCFA 132 +PI G L D +GR+P ++ IVVF S G SM L+ R +QGIGGG L+ F Sbjct: 73 IPIVGTLSDRYGRRPLILLGIVVFALGSMGLGFVQSMEQLIALRAIQGIGGGTLMAMSFT 132 Query: 133 SIADLFPDPRVRLRWQIILSASFGIATAVGPSLGGFLTQGLGWRWVFYCNLPIGVLSLYF 192 +IADLF P R R+Q A +GI++ VGP +GGFLT GWR VF+ NLP +L+L+F Sbjct: 133 AIADLF-TPIERGRYQGYTGAVWGISSVVGPLVGGFLTDHFGWRSVFFLNLPFALLALFF 191 Query: 193 VWRFVPHIRHMQHAGKMRLDWPGALLISLSLGSLQLLVELLPKRGITGGMMVLLAVSVAA 252 +WRF + K D GA L++ ++ +L L V +L + Sbjct: 192 IWRFFRLPAPTPGSVKGGFDALGATLLAGAVTTLTLAVSWGGGTYAWDSPRILGLLGATL 251 Query: 253 FYALWRWEQRAAQP--ILPFEMMRDKALASLFVLSVLAGF----AMFSLLMYAPLLFQGG 306 W A Q IL ++RD+ + +L+ LAGF M++ ++Y PL QG Sbjct: 252 ALGAWYAAHSARQERAILDLGLLRDRGI----LLASLAGFLVSAGMYAAILYLPLYMQGV 307 Query: 307 FGLSPREAGLLITPLVACITVASIVNGRIITRIPNPNLMMNLGFALIAASCLGVVLCDRT 366 G S +GL + PL+ + + S ++G++++R ++ +G AL+A+ L + Sbjct: 308 RGSSASGSGLALAPLMGGMILTSTLSGQLVSRTGRYKRLI-VGGALVASLALVLSSTLSL 366 Query: 367 TGNGFL-LTVMLAGGFGLGLVLPNLTVFAQQAAAREHLGIATALLQSLRMIGGMLGTAIT 425 + +L +T+M+ G GLG V LT+ Q AA R+ LG AT Q R IGG L ++ Sbjct: 367 STPLWLAVTMMILLGLGLGPVNSQLTLAVQNAAPRQKLGSATGGNQFFRQIGGTLAVSLF 426 Query: 426 GTLVSQMYGAGVQKALEG---DHAAQWLKDFSDPEVLVNHDIQSVLLAQLMQAGHDG--S 480 G LV+ + L A ++P +L + +L L + GH + Sbjct: 427 GALVNAHLSHDLSAKLPAAVRRLPAPMQDAIANPNLLTSERATHLLGWALKKMGHHEMLA 486 Query: 481 ALLEAAREALVGAI 494 +++A R +VGAI Sbjct: 487 PIMQALRGVMVGAI 500 >DRA0061 [GEPR] COG0477 Permeases of the major facilitator superfamily Dra Deinococcus radiodurans Length = 643 Score = 213 bits (541), Expect = 1e-54, Method: Compositional matrix adjust. Identities = 160/444 (36%), Positives = 234/444 (52%), Gaps = 31/444 (6%) Query: 6 DAAH--SSGQVLPFRESLLATLGICFVIMLVALDQTIVGTALPTIVAELKGFDLYAWVAT 63 D AH + ++L R G+ + L ALDQTIV ALP IV+EL G +LY+WV T Sbjct: 12 DPAHYINYAELLDLRTKKFIVFGVLLALFLSALDQTIVSAALPRIVSELNGLNLYSWVTT 71 Query: 64 AYLLTSVITVPIFGRLGDYFGRKPFVIASIVVFVGASALCGMA----------NSMLFLV 113 AYLL+S VPI+G+L D +GRKP ++ IVVF+ SALCG++ + M+ LV Sbjct: 72 AYLLSSAALVPIYGKLSDLYGRKPVLVFGIVVFLIGSALCGLSGEPFLGNLFGSPMMQLV 131 Query: 114 LARGLQGIGGGMLVGTCFASIADLFPDPRVRLRWQIILSASFGIATAVGPSLGGFLTQGL 173 + RGLQGIG L FA +ADLF +PR R ++Q + A FG+++ VGP LGGFLT L Sbjct: 132 VFRGLQGIGAAALATVAFAIVADLF-EPRERAKYQGLFGAVFGLSSVVGPLLGGFLTDQL 190 Query: 174 GWRWVFYCNLPIGVLSLYFVWRFVPHIRHMQHAGKMR--LDWPGALLISLSLGSLQLLVE 231 WRWVFY N+PIG+++L ++ +P + A +R +D+ GA+LI + ++ LL+ Sbjct: 191 SWRWVFYVNVPIGLVALAVIFARMPRL-----ASGLRGSVDYLGAVLIVIF--TVPLLLA 243 Query: 232 LLPKRGITGG-----MMVLLAVSVAAFYALWRWEQRAAQPILPFEMMRDKALASLFVLSV 286 L T G M+ L S+AA A WE+R PI+P + D +A Sbjct: 244 LTWGADGTAGWTDAKMLGLFGTSLAALLAFIFWERRHESPIVPLTLFADPTIAWTMTSRF 303 Query: 287 LAGFAMFSLLMYAPLLFQGGFGLSPREAGLLITPLVACITVASIVNGRIITRIPNPNLMM 346 L G +++ L G S AGL PL + + +G + R + ++ Sbjct: 304 LLGAGFLGAVLFLTLYLVNVAGFSATGAGLATLPLTLGFVIGAQGSGLLAARSGHYKSLL 363 Query: 347 NLGF--ALIAASCLGVVLCDRTTGNGFLLTVMLAGGFGLGLVLPNLTVFAQQAAAREHLG 404 + A++A L V D T G L M G GLG + T+ AQ A A +G Sbjct: 364 VGAYVVAVLAFWWLSTVQVD--TPYGLLAARMFLVGLGLGPSVSLFTLAAQNAVAPYQIG 421 Query: 405 IATALLQSLRMIGGMLGTAITGTL 428 + T++ + +GG +G A+ G + Sbjct: 422 VVTSVGTFFQQLGGTIGIALFGAI 445 >DR1327 [GEPR] COG0477 Permeases of the major facilitator superfamily Dra Deinococcus radiodurans Length = 477 Score = 213 bits (541), Expect = 1e-54, Method: Compositional matrix adjust. Identities = 158/439 (35%), Positives = 232/439 (52%), Gaps = 25/439 (5%) Query: 18 RESLLATLGICFVIMLVALDQTIVGTALPTIVAELKGFDLYAWVATAYLLTSVITVPIFG 77 R LLAT+G+ + L AL+ ++V TA+P+++ +L G LYA YLLTS + P++G Sbjct: 14 RARLLATVGLIVGVFLNALESSVVATAMPSVINDLHGQSLYALPFAMYLLTSTVGSPLWG 73 Query: 78 RLGDYFGRKPFVIASIVVFVGASALCGMANSMLFLVLARGLQGIGGGMLVGTCFASIADL 137 R D GRK + V+F+ SALCG A SM +L+ AR LQG+G G L+ + +L Sbjct: 74 RASDLVGRKRLYLVGAVLFLVGSALCGAAQSMGWLIGARALQGLGAGALLTLSMTIVGEL 133 Query: 138 FPDPRVRLRWQIILSASFGIATAVGPSLGGFLTQGLGWRWVFYCNLPIGVLSLYFVWRFV 197 + + R R Q +SA +GI+ GP LGG+LT+ L WRW FY +LP G+L+L+ V RF+ Sbjct: 134 Y-SLQERSRVQAFISAVWGISGLAGPLLGGWLTETLSWRWTFYVSLPFGLLALFMVSRFL 192 Query: 198 PHIRHMQHAGKMRLDWPGALLISLSLGSLQLLVELLPKRGITGGMMVLLAVSVAAFYALW 257 + A +LDW GA L +L G L G+ + L+ + VA Sbjct: 193 HETGERRAA---QLDWAGAALFTLGSG--------LTIWGLEMKLWSLVGLGVATLVGAV 241 Query: 258 RWEQRAAQPILPFEMMRDKALASLFVLSVLAGFAMFSLLMYAPLLFQGGFGLSPREAGLL 317 E R P+LP +R++ A F + L G A F ++ Y PL QG G AG + Sbjct: 242 LLELRHPAPLLPMRALRERTPAVAFAGNFLGGAAYFGVIAYLPLYAQGVSGKGATAAGAI 301 Query: 318 ITPLVACITVASIVNGRIITRIPNPNLMMNLGFALIAASCLGVVLCDR-----TTGNGFL 372 +TP++ T+ SI++ ++I IP L +GFAL+ L + T+ GF Sbjct: 302 LTPMLVGWTLTSILSAQLIRFIPLARL-SQIGFALLTLMFLALTFTVHSPLWVTSALGF- 359 Query: 373 LTVMLAGGFGLGLVLPNLTVFAQQAAAREHLGIATALLQSLRMIGGMLGTAITGTLV-SQ 431 A G G+G + +L + AQQAA+R LG T+ + R +GG LGTA+ L+ S Sbjct: 360 -----AVGMGMGFSMLSLLLAAQQAASRGELGAVTSGVMFARQMGGALGTALMALLIGSH 414 Query: 432 MYGAGVQKALEGDHAAQWL 450 G G + EG A +L Sbjct: 415 AIGVGGIELAEGLRRAYFL 433