BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0028.0144.p (405 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value aq_183 [S] COG3034 Uncharacterized protein conserved in bacteria... 105 1e-22 jhp0467 [S] COG3034 Uncharacterized protein conserved in bacteri... 94 8e-19 HP0518 [S] COG3034 Uncharacterized protein conserved in bacteria... 92 2e-18 Cj0906c [S] COG3034 Uncharacterized protein conserved in bacteri... 80 8e-15 >aq_183 [S] COG3034 Uncharacterized protein conserved in bacteria Aae Aquifex aeolicus Length = 397 Score = 105 bits (263), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 82/295 (27%), Positives = 144/295 (48%), Gaps = 25/295 (8%) Query: 116 RIRSLQEKPDPKLIPKAVLQVGEDQKNVLVVDTTRSRLYVYENQGGELKYMTDYYVSQGR 175 +IR + EK + P VL + V +V+ L+V+ +G +L+ M Y V+ G Sbjct: 114 KIRKILEKRFKEAPP--VLVENPENHYVFLVEKMSQYLFVF--KGKKLEGM--YPVTTGM 167 Query: 176 FGANKTKSGDQRTPIGVYYVNNRIPGPKLPDFYGTGALPLSYPNEWDKRNGRSGYGIWLH 235 +K + GD +TP GVYY IP +L + YG A+ L+YPN +DK G++G GIWLH Sbjct: 168 NIGDKEREGDGKTPEGVYYFTRFIPPEQLSEIYGGIAVALNYPNPYDKLLGKTGSGIWLH 227 Query: 236 GTPSDNFSRPPLSSDGCVVLANPDLQS-LYSTAEVGKTVV----VISQHVQFVDKSEWAK 290 G+ + + P S+ GCVV L++ + + T++ VI Q ++ + E+ Sbjct: 228 GSNEKDRDKLPFSTRGCVVAQTDVLKTEIVPKINLSNTLIGIYKVIPQSLEVENVKEF-- 285 Query: 291 QRDAASAMLEQWGQSLENADADKVLSYYSPEFRSAQGENLATWFGRQQKSLNGARYTSVK 350 + W + E D ++ +S+YS FR +G L W +++++ ++ V Sbjct: 286 --------ILSWKNAWEKKDLNRFISFYSKHFR-WKGGGLKEWKDYKKRTILSKKFIKVD 336 Query: 351 LRDVSLFRYPGTPED---MIVSTFTQESAVGKSKNAIRKRQYWVREGSQWKIIYE 402 + ++S+ + +D V F Q+ + KR Y V+E + K++ E Sbjct: 337 ISNLSILAFSKLGDDEPRYYVIEFYQKYRSDTYSDEGIKRMYVVKEDGKLKVLSE 391 >jhp0467 [S] COG3034 Uncharacterized protein conserved in bacteria jHp Helicobacter pylori J99 Length = 330 Score = 93.6 bits (231), Expect = 8e-19, Method: Compositional matrix adjust. Identities = 67/272 (24%), Positives = 125/272 (45%), Gaps = 14/272 (5%) Query: 138 EDQKNVLVVDTTRSRLYVYENQGGELKYMTDYYVSQGRFGANKTKSGDQRTPIGVYYVNN 197 ++++ + V D ++ L YE + LK + G +KT GD TPIGVY + Sbjct: 65 QNKQFLFVADKSKPSLEFYEIENNMLKKINSSKALVGSKKGDKTLEGDLATPIGVYRITQ 124 Query: 198 RIPGPKLPDFYGTGALPLSYPNEWDKRNGRSGYGIWLHGTPSDNFSRPPLSSDGCVVLAN 257 ++ +L +YG A +YPN +D R+G+GIW+HG P N R L++ GC+ + N Sbjct: 125 KLE--RLDQYYGVLAFVTNYPNLYDTLKKRTGHGIWVHGMPL-NGDRNELNTKGCIAIEN 181 Query: 258 PDLQSLYSTAEVGKTVVVISQHVQFVDKSEWAKQRDAASAMLEQWGQSLENADADKVLSY 317 P L S Y G+ +I+ +F ++ ++ + L QW ++ D ++ + + Sbjct: 182 PILSS-YDKVLKGEKAFLITYEDKFSPSTK--EELSMILSSLFQWKEAWARGDFERYMRF 238 Query: 318 YSPEFRSAQGENLATWFGRQQKSLNGARYTSVKLRDVSLFRYPGTPEDMIVSTFT----- 372 Y+P F G + + +++ ++ +++ YP + + Sbjct: 239 YNPNFTRYDGMSFNAFKEYKKRVFAKNEKKNIAFSSINVIPYPNSQNKRLFYVVFDQDYK 298 Query: 373 --QESAVGKSKNAIRKRQYWVREGSQWKIIYE 402 Q++ + S N+ +K Y E +Q II E Sbjct: 299 AYQQNKLSYSSNS-QKELYVEIENNQASIIME 329 >HP0518 [S] COG3034 Uncharacterized protein conserved in bacteria Hpy Helicobacter pylori 26695 Length = 330 Score = 92.0 bits (227), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 67/272 (24%), Positives = 125/272 (45%), Gaps = 14/272 (5%) Query: 138 EDQKNVLVVDTTRSRLYVYENQGGELKYMTDYYVSQGRFGANKTKSGDQRTPIGVYYVNN 197 ++++ + V + ++ L YE + LK + G +KT GD TPIGVY + Sbjct: 65 QNKQFLFVANKSKPSLEFYEIENNMLKKINSSKALVGSKKGDKTLEGDLATPIGVYRITQ 124 Query: 198 RIPGPKLPDFYGTGALPLSYPNEWDKRNGRSGYGIWLHGTPSDNFSRPPLSSDGCVVLAN 257 ++ +L +YG A +YPN +D R+G+GIW+HG P N R L++ GC+ + N Sbjct: 125 KLE--RLDQYYGVLAFVTNYPNLYDTLKKRTGHGIWVHGMPL-NGDRNELNTKGCIAIEN 181 Query: 258 PDLQSLYSTAEVGKTVVVISQHVQFVDKSEWAKQRDAASAMLEQWGQSLENADADKVLSY 317 P L S Y G+ +I+ +F ++ ++ + L QW ++ D ++ + + Sbjct: 182 PLLSS-YDKVLKGEKAFLITYEDKFFPSTK--EELSMILSSLFQWKEAWARGDFERYMRF 238 Query: 318 YSPEFRSAQGENLATWFGRQQKSLNGARYTSVKLRDVSLFRYPGTPED-MIVSTFTQE-- 374 Y+P F G + +++ ++ +++ YP + + F Q+ Sbjct: 239 YNPNFTRYDGMKFNAFKEYKKRVFAKNEKKNIAFSSINVIPYPNSQNKRLFYVVFDQDYK 298 Query: 375 ----SAVGKSKNAIRKRQYWVREGSQWKIIYE 402 + + S N+ +K Y E +Q II E Sbjct: 299 AYQHNKLSYSSNS-QKELYIEIENNQVSIIME 329 >Cj0906c [S] COG3034 Uncharacterized protein conserved in bacteria Cje Campylobacter jejuni Length = 325 Score = 80.1 bits (196), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 62/232 (26%), Positives = 103/232 (44%), Gaps = 12/232 (5%) Query: 134 LQVGEDQKNVLVVDTTRS----RLYVYENQGGELKYMTDYYVSQGRFGANKTKSGDQRTP 189 + +G NV +V T ++ R+Y YE+ G K + G G K + GD +TP Sbjct: 56 ISLGYYDDNVAIVLTNKTDKILRVYSYED-GKIRKDFEQKEIITGLMGDKKIE-GDLKTP 113 Query: 190 IGVYYVNNRIPGPKLPDFYGTGALPLSYPNEWDKRNGRSGYGIWLHGTPSDNFSRPPLSS 249 +G Y + + P P +YG A +YPN DK G++G GIW+HG P D + Sbjct: 114 VGFYELGRKF-NPGDP-YYGPFAFATTYPNLLDKVQGKTGGGIWIHGYPLDGSRLDEFKT 171 Query: 250 DGCVVLANPDLQSLYSTAEVGKTVVVISQHVQFVDKSEWAKQRDAASAMLEQWGQSLENA 309 GC+ L N +L+ + K V+ + + K + Q + A L W + N+ Sbjct: 172 RGCIALFNNNLEKFAKVVQDKKVFVMTEEKEKIRAKKD---QIASLLADLFTWKLAWTNS 228 Query: 310 DADKVLSYYSP-EFRSAQGENLATWFGRQQKSLNGARYTSVKLRDVSLFRYP 360 D + LS+Y EF+ + ++ + +K D+++ YP Sbjct: 229 DTNAYLSFYDEQEFKRFDKMKFEQFASMKKSIFSRKEDKKIKFSDINISPYP 280