BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0028.0076.p (251 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1052 [IQR] COG1028 Dehydrogenases with different specificitie... 348 6e-96 VC2021 [IQR] COG1028 Dehydrogenases with different specificities... 320 1e-87 fabG [IQR] COG1028 Dehydrogenases with different specificities (... 320 2e-87 ZfabG [IQR] COG1028 Dehydrogenases with different specificities ... 320 2e-87 ECs1471 [IQR] COG1028 Dehydrogenases with different specificitie... 320 2e-87 >RSc1052 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Rso Ralstonia solanacearum Length = 249 Score = 348 bits (893), Expect = 6e-96, Method: Compositional matrix adjust. Identities = 182/246 (73%), Positives = 203/246 (82%), Gaps = 1/246 (0%) Query: 6 LQGQVALVTGASRGIGRAIATELARQGAKVVGTATSESGAAAITEYLAALGPEAGRGAVL 65 L QVALVTGASRGIGRAIA ELARQGA VVGTATSE+GA AI+ Y A G + G G VL Sbjct: 5 LNNQVALVTGASRGIGRAIALELARQGATVVGTATSEAGAQAISAYFAEAGVK-GAGVVL 63 Query: 66 NVNDAEASVALVEQVQKEFGALSILVNNAGITQDQLAMRMKDEEWDSVIATNLTAVGRLS 125 NVNDA A++++ K G L+ILVNNAGITQD LAMRMKD+EW +VI TNL+AV RLS Sbjct: 64 NVNDAARCEAVIDEAIKTHGGLNILVNNAGITQDNLAMRMKDDEWMAVIDTNLSAVFRLS 123 Query: 126 RAVLRGMMKARSGRIISITSVVGEAGNPGQMNYAAAKAGVAGMSRALAREIGSRNITVNC 185 RAVLR MMKAR GRII+ITSVVG AGNPGQ NYAAAKAGV GM+RA+A+EIGSRNITVN Sbjct: 124 RAVLRPMMKARGGRIINITSVVGSAGNPGQANYAAAKAGVEGMARAMAKEIGSRNITVNS 183 Query: 186 VAPGFIDTDMTKALNEQQSAAILQQIPLGRLGAAEEIAYAVAFLASPQAAYITGTTLNVN 245 VAPGFIDTDMTK L+++Q A+ QIPLGRLG E+IA AVAFLASP A YITG TL+VN Sbjct: 184 VAPGFIDTDMTKVLSDEQHTALKAQIPLGRLGMPEDIANAVAFLASPAAGYITGATLHVN 243 Query: 246 GGMYMG 251 GGMYMG Sbjct: 244 GGMYMG 249 >VC2021 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Vch Vibrio cholerae Length = 248 Score = 320 bits (821), Expect = 1e-87, Method: Compositional matrix adjust. Identities = 160/247 (64%), Positives = 198/247 (80%), Gaps = 4/247 (1%) Query: 4 LNLQGQVALVTGASRGIGRAIATELARQGAKVVGTATSESGAAAITEYLAALGPEAGRGA 63 +NL+G+VALVTGASRGIG+AIA LA +GAKV+GTATSESGA AI++YL + G+G Sbjct: 5 MNLEGKVALVTGASRGIGKAIAELLAERGAKVIGTATSESGAQAISDYLG----DNGKGM 60 Query: 64 VLNVNDAEASVALVEQVQKEFGALSILVNNAGITQDQLAMRMKDEEWDSVIATNLTAVGR 123 LNV + E+ A+++ + EFG + ILVNNAGIT+D L MRMK+EEW ++ TNLT++ R Sbjct: 61 ALNVTNPESIEAVLKAITDEFGGVDILVNNAGITRDNLLMRMKEEEWSDIMETNLTSIFR 120 Query: 124 LSRAVLRGMMKARSGRIISITSVVGEAGNPGQMNYAAAKAGVAGMSRALAREIGSRNITV 183 LS+AVLRGMMK R GRII++ SVVG GN GQ NYAAAKAGV G ++++ARE+ SR +TV Sbjct: 121 LSKAVLRGMMKKRQGRIINVGSVVGTMGNAGQANYAAAKAGVIGFTKSMAREVASRGVTV 180 Query: 184 NCVAPGFIDTDMTKALNEQQSAAILQQIPLGRLGAAEEIAYAVAFLASPQAAYITGTTLN 243 N VAPGFI+TDMTKALN++Q A L Q+P GRLG EIA AVAFLASP+AAYITG TL+ Sbjct: 181 NTVAPGFIETDMTKALNDEQRTATLAQVPAGRLGDPREIASAVAFLASPEAAYITGETLH 240 Query: 244 VNGGMYM 250 VNGGMYM Sbjct: 241 VNGGMYM 247 >fabG [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Eco Escherichia coli K12 Length = 244 Score = 320 bits (820), Expect = 2e-87, Method: Compositional matrix adjust. Identities = 161/247 (65%), Positives = 200/247 (80%), Gaps = 4/247 (1%) Query: 4 LNLQGQVALVTGASRGIGRAIATELARQGAKVVGTATSESGAAAITEYLAALGPEAGRGA 63 +N +G++ALVTGASRGIGRAIA LA +GAKV+GTATSE+GA AI++YL A G+G Sbjct: 1 MNFEGKIALVTGASRGIGRAIAETLAARGAKVIGTATSENGAQAISDYLGA----NGKGL 56 Query: 64 VLNVNDAEASVALVEQVQKEFGALSILVNNAGITQDQLAMRMKDEEWDSVIATNLTAVGR 123 +LNV D + +++E+++ EFG + ILVNNAGIT+D L MRMKDEEW+ +I TNL++V R Sbjct: 57 MLNVTDPASIESVLEKIRAEFGEVDILVNNAGITRDNLLMRMKDEEWNDIIETNLSSVFR 116 Query: 124 LSRAVLRGMMKARSGRIISITSVVGEAGNPGQMNYAAAKAGVAGMSRALAREIGSRNITV 183 LS+AV+R MMK R GRII+I SVVG GN GQ NYAAAKAG+ G S++LARE+ SR ITV Sbjct: 117 LSKAVMRAMMKKRHGRIITIGSVVGTMGNGGQANYAAAKAGLIGFSKSLAREVASRGITV 176 Query: 184 NCVAPGFIDTDMTKALNEQQSAAILQQIPLGRLGAAEEIAYAVAFLASPQAAYITGTTLN 243 N VAPGFI+TDMT+AL++ Q A IL Q+P GRLG A+EIA AVAFLAS +AAYITG TL+ Sbjct: 177 NVVAPGFIETDMTRALSDDQRAGILAQVPAGRLGGAQEIANAVAFLASDEAAYITGETLH 236 Query: 244 VNGGMYM 250 VNGGMYM Sbjct: 237 VNGGMYM 243 >ZfabG [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) EcZ Escherichia coli O157:H7 EDL933 Length = 244 Score = 320 bits (820), Expect = 2e-87, Method: Compositional matrix adjust. Identities = 161/247 (65%), Positives = 200/247 (80%), Gaps = 4/247 (1%) Query: 4 LNLQGQVALVTGASRGIGRAIATELARQGAKVVGTATSESGAAAITEYLAALGPEAGRGA 63 +N +G++ALVTGASRGIGRAIA LA +GAKV+GTATSE+GA AI++YL A G+G Sbjct: 1 MNFEGKIALVTGASRGIGRAIAETLAARGAKVIGTATSENGAQAISDYLGA----NGKGL 56 Query: 64 VLNVNDAEASVALVEQVQKEFGALSILVNNAGITQDQLAMRMKDEEWDSVIATNLTAVGR 123 +LNV D + +++E+++ EFG + ILVNNAGIT+D L MRMKDEEW+ +I TNL++V R Sbjct: 57 MLNVTDPASIESVLEKIRAEFGEVDILVNNAGITRDNLLMRMKDEEWNDIIETNLSSVFR 116 Query: 124 LSRAVLRGMMKARSGRIISITSVVGEAGNPGQMNYAAAKAGVAGMSRALAREIGSRNITV 183 LS+AV+R MMK R GRII+I SVVG GN GQ NYAAAKAG+ G S++LARE+ SR ITV Sbjct: 117 LSKAVMRAMMKKRHGRIITIGSVVGTMGNGGQANYAAAKAGLIGFSKSLAREVASRGITV 176 Query: 184 NCVAPGFIDTDMTKALNEQQSAAILQQIPLGRLGAAEEIAYAVAFLASPQAAYITGTTLN 243 N VAPGFI+TDMT+AL++ Q A IL Q+P GRLG A+EIA AVAFLAS +AAYITG TL+ Sbjct: 177 NVVAPGFIETDMTRALSDDQRAGILVQVPAGRLGGAQEIANAVAFLASDEAAYITGETLH 236 Query: 244 VNGGMYM 250 VNGGMYM Sbjct: 237 VNGGMYM 243 >ECs1471 [IQR] COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Ecs Escherichia coli O157:H7 Length = 244 Score = 320 bits (820), Expect = 2e-87, Method: Compositional matrix adjust. Identities = 161/247 (65%), Positives = 200/247 (80%), Gaps = 4/247 (1%) Query: 4 LNLQGQVALVTGASRGIGRAIATELARQGAKVVGTATSESGAAAITEYLAALGPEAGRGA 63 +N +G++ALVTGASRGIGRAIA LA +GAKV+GTATSE+GA AI++YL A G+G Sbjct: 1 MNFEGKIALVTGASRGIGRAIAETLAARGAKVIGTATSENGAQAISDYLGA----NGKGL 56 Query: 64 VLNVNDAEASVALVEQVQKEFGALSILVNNAGITQDQLAMRMKDEEWDSVIATNLTAVGR 123 +LNV D + +++E+++ EFG + ILVNNAGIT+D L MRMKDEEW+ +I TNL++V R Sbjct: 57 MLNVTDPASIESVLEKIRAEFGEVDILVNNAGITRDNLLMRMKDEEWNDIIETNLSSVFR 116 Query: 124 LSRAVLRGMMKARSGRIISITSVVGEAGNPGQMNYAAAKAGVAGMSRALAREIGSRNITV 183 LS+AV+R MMK R GRII+I SVVG GN GQ NYAAAKAG+ G S++LARE+ SR ITV Sbjct: 117 LSKAVMRAMMKKRHGRIITIGSVVGTMGNGGQANYAAAKAGLIGFSKSLAREVASRGITV 176 Query: 184 NCVAPGFIDTDMTKALNEQQSAAILQQIPLGRLGAAEEIAYAVAFLASPQAAYITGTTLN 243 N VAPGFI+TDMT+AL++ Q A IL Q+P GRLG A+EIA AVAFLAS +AAYITG TL+ Sbjct: 177 NVVAPGFIETDMTRALSDDQRAGILVQVPAGRLGGAQEIANAVAFLASDEAAYITGETLH 236 Query: 244 VNGGMYM 250 VNGGMYM Sbjct: 237 VNGGMYM 243