BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0028.0058.p (606 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc1071 [L] COG0322 Nuclease subunit of the excinuclease complex... 906 0.0 NMA1540 [L] COG0322 Nuclease subunit of the excinuclease complex... 630 e-180 NMB1326 [L] COG0322 Nuclease subunit of the excinuclease complex... 617 e-176 PA2585 [L] COG0322 Nuclease subunit of the excinuclease complex ... 580 e-165 XF2311 [L] COG0322 Nuclease subunit of the excinuclease complex ... 531 e-150 >RSc1071 [L] COG0322 Nuclease subunit of the excinuclease complex Rso Ralstonia solanacearum Length = 654 Score = 906 bits (2342), Expect = 0.0, Method: Compositional matrix adjust. Identities = 453/628 (72%), Positives = 511/628 (81%), Gaps = 26/628 (4%) Query: 5 VARLPHLPGVYRYFDAEDNVLYVGKARDLKKRVSSYFQKTLTSPRIAMMVERIARLETTV 64 +ARLP LPGVYRYFDA+ +VLYVGKARDLKKRVSSYF KTL SPRIAMMV +IA +ETTV Sbjct: 27 IARLPSLPGVYRYFDAQGSVLYVGKARDLKKRVSSYFTKTLLSPRIAMMVAKIAHIETTV 86 Query: 65 TRSEAEALLLENNLIKTLRPRFNILFRDDKSYPYLKITGHAFPRMAYYRGAVDKRSQYFG 124 RSEAEALLLENNLIK L PR+NILFRDDKSYPYLK+T HA+PRMAYYRGA D++ QYFG Sbjct: 87 VRSEAEALLLENNLIKALAPRYNILFRDDKSYPYLKLTQHAYPRMAYYRGATDRKHQYFG 146 Query: 125 PFPNAGAVKESIQILQKVFLLRTCEDTVFTNRTRPCLLHQIHRCSGPCVNLVSREDYALD 184 PFP+A AV+ES+QILQKVF LRTCEDTVF NRTRPCLLHQIHRC+ PCV +S EDYA D Sbjct: 147 PFPSAHAVRESMQILQKVFQLRTCEDTVFNNRTRPCLLHQIHRCTAPCVQAISAEDYARD 206 Query: 185 VENASKFLRGRQSEVMEALEQKMHAFAADLKFEQAAAVRDQIGSLSSVLHQQSMETVSDA 244 V NA+ FL GRQ EVM+ L+ KM AA L+FEQAA VRDQIG+LS+VL +QS+E V A Sbjct: 207 VANAAGFLLGRQDEVMQTLQDKMQRHAAALEFEQAATVRDQIGALSTVLTRQSVEEVGQA 266 Query: 245 -DIDIIAVTVQGGRACVNLAMVRGGRHLGDRAYFPTHVD------------DAMDTAE-- 289 DIDI+AV ++GG ACVNLAMVRGGRHLGD+AYFPTHV+ D + AE Sbjct: 267 SDIDILAVAIKGGHACVNLAMVRGGRHLGDKAYFPTHVEEGAAIVGVDVEADVPEGAETQ 326 Query: 290 -------ESIEVEVLKAFLAQHYIDKFIPGSLIVGTEFDDPALMMALMEQCGHRITLTFQ 342 E + ++L+AF+AQHY+D+F+P L+V L+ AL Q G R+++ Q Sbjct: 327 PEPARDPERMARDILEAFVAQHYLDQFVPPVLVVSHPIRAAGLIEALAAQAGRRVSVVRQ 386 Query: 343 PQGQRRQWLEMAAKGAEIALARLLSEQGSQQARTRALAEVLELEREDLDELRAECFDISH 402 PQG RR WLEMA KGAE++LAR LSEQGSQQARTRALAE + ++ EDL LR ECFDISH Sbjct: 387 PQGARRAWLEMAEKGAELSLARRLSEQGSQQARTRALAETIGVDLEDLAALRVECFDISH 446 Query: 403 TQGEATQASCVVFHHHAMQNGEYRRYNINDITPGDDYAAMRQVLTRRYEKV----ANGEG 458 T GEATQASCVVFH HAMQNGEYRRYNI DI PGDDYAAMRQVLTRRY+KV A Sbjct: 447 TAGEATQASCVVFHSHAMQNGEYRRYNIQDIIPGDDYAAMRQVLTRRYQKVVEQAAEDAP 506 Query: 459 VMPDIVLIDGGKGQVEMARQVLTELGLDISLIVGVAKGEGRKVGLETLVFADGRAPKELG 518 MP +VLIDGGKGQVE+ARQV ELGLDI L+VGVAKGEGRKVGLETLVFADGR ELG Sbjct: 507 DMPRVVLIDGGKGQVEVARQVFEELGLDIGLLVGVAKGEGRKVGLETLVFADGRPSLELG 566 Query: 519 KESAALMLIAQIRDEAHRFAITGMRAKRAKARQTSRLEEIEGIGAKRRQRLLVRFGGLRG 578 + SAALML+AQIRDEAHRFAITGMRAKRAKAR TSRLEEIEGIGAKRRQRLL RFGGLRG Sbjct: 567 QGSAALMLVAQIRDEAHRFAITGMRAKRAKARNTSRLEEIEGIGAKRRQRLLARFGGLRG 626 Query: 579 VVDASVDDLASVEGISRQLAEEIYRQLH 606 V+ ASV++LA+VEGIS+ LAEEIYRQLH Sbjct: 627 VMAASVEELATVEGISQTLAEEIYRQLH 654 >NMA1540 [L] COG0322 Nuclease subunit of the excinuclease complex NmA Neisseria meningitidis Z2491 Length = 628 Score = 630 bits (1626), Expect = e-180, Method: Compositional matrix adjust. Identities = 325/610 (53%), Positives = 418/610 (68%), Gaps = 17/610 (2%) Query: 5 VARLPHLPGVYRYFDAEDNVLYVGKARDLKKRVSSYFQKTLTSPRIAMMVERIARLETTV 64 + LP LPGVYR+FD VLYVGKA +LK+RVS YFQK SPRIA+MV+++ +ETT+ Sbjct: 28 LKNLPKLPGVYRFFDEGGKVLYVGKAVNLKRRVSGYFQKNDHSPRIALMVKQVHHIETTI 87 Query: 65 TRSEAEALLLENNLIKTLRPRFNILFRDDKSYPYLKITGHAFPRMAYYRGAVDKRSQYFG 124 TRSEAEAL+LENN IK L P++NILFRDDKSYPYL ++GH +P+MAYYRG + K +QYFG Sbjct: 88 TRSEAEALILENNFIKALSPKYNILFRDDKSYPYLMLSGHQYPQMAYYRGTLKKPNQYFG 147 Query: 125 PFPNAGAVKESIQILQKVFLLRTCEDTVFTNRTRPCLLHQIHRCSGPCVNLVSREDYALD 184 P+PN+ AV++SIQILQKVF+LRTCED+VF +R RPCLL+QI RC+ PCV +S EDY Sbjct: 148 PYPNSNAVRDSIQILQKVFMLRTCEDSVFEHRDRPCLLYQIKRCTAPCVGHISEEDYRDS 207 Query: 185 VENASKFLRGRQSEVMEALEQKMHAFAADLKFEQAAAVRDQIGSLSSVLHQQ---SMETV 241 V A+ FL G+ E+ L+ KM AA+L+FE+AA RDQI +L + Q S Sbjct: 208 VRQAATFLNGKTDELTRTLQHKMQTAAANLQFEEAARYRDQIQALGIMQSNQFIDSKNPN 267 Query: 242 SDADIDIIAVTVQGGRACVNLAMVRGGRHLGDRAYFPTHVDDAMDTAEESIEVEVLKAFL 301 + DID++A+ V G CV+ +RGGRH+GD+++FP +D ++ E AF+ Sbjct: 268 NPNDIDLLALAVSDGLVCVHWVSIRGGRHVGDKSFFPDTKNDPEPNGQDYAE-----AFV 322 Query: 302 AQHYIDKFIPGSLIVGTEFDDPALMMALMEQCGHRITLTFQPQGQRRQWLEMAAKGAEIA 361 AQHY+ K P +I D AL AL + G ++ + G+R+ WL+MA + A++A Sbjct: 323 AQHYLGKSKPDIIINNFPVPD-ALKEALEGEHGKQMQFVTKTIGERKVWLKMAEQNAQMA 381 Query: 362 LARLLSEQGSQQARTRALAEVLELEREDLDELRAECFDISHTQGEATQASCVVFHHHAMQ 421 +A+ +Q +QQ R LA++L ++ + L+ R ECFDISHTQGEAT ASCVV+ +Q Sbjct: 382 IAQRRLQQSNQQHRIDELAKILGMDSDGLN--RLECFDISHTQGEATIASCVVYDEQNIQ 439 Query: 422 NGEYRRYNINDITPGDDYAAMRQVLTRRYEKV----ANGEGV-MPDIVLIDGGKGQVEMA 476 +YRRYNI PGDDYAAMR+VLTRRY K+ ANGE V PD VLIDGGKGQ+ +A Sbjct: 440 PSQYRRYNITTAKPGDDYAAMREVLTRRYGKMQEAEANGETVKWPDAVLIDGGKGQIGIA 499 Query: 477 RQVLTELGLDISLIVGVAKGEGRKVGLETLVFADGRAPKELGKESAALMLIAQIRDEAHR 536 V ELGL I L VG+AKG RK G+E L+ L S AL L+ +RDE+HR Sbjct: 500 VSVWEELGLHIPL-VGIAKGPERKAGMEELILPFTGEVFRLPPNSPALHLLQTVRDESHR 558 Query: 537 FAITGMRAKRAKARQTSRLEEIEGIGAKRRQRLLVRFGGLRGVVDASVDDLASVEGISRQ 596 FAITG R KR KAR TS L +I G+G+KRRQ LL RFGGLRGV+ AS +DL VEGIS+ Sbjct: 559 FAITGHRKKRDKARVTSSLSDIPGVGSKRRQALLTRFGGLRGVIAASREDLEKVEGISKA 618 Query: 597 LAEEIYRQLH 606 LAE IY LH Sbjct: 619 LAETIYEHLH 628 >NMB1326 [L] COG0322 Nuclease subunit of the excinuclease complex Nme Neisseria meningitidis MC58 Length = 617 Score = 617 bits (1592), Expect = e-176, Method: Compositional matrix adjust. Identities = 323/610 (52%), Positives = 419/610 (68%), Gaps = 17/610 (2%) Query: 5 VARLPHLPGVYRYFDAEDNVLYVGKARDLKKRVSSYFQKTLTSPRIAMMVERIARLETTV 64 + LP+LPGVYR+F+ NVLYVGKA +LK+RVS YFQK SPRIA+MV+++ +ETT+ Sbjct: 17 LKNLPNLPGVYRFFNESGNVLYVGKAVNLKRRVSGYFQKNDHSPRIALMVKQVHHIETTI 76 Query: 65 TRSEAEALLLENNLIKTLRPRFNILFRDDKSYPYLKITGHAFPRMAYYRGAVDKRSQYFG 124 TRSE+EAL+LENN IK L P++NILFRDDKSYPYL ++GH +P+MAYYRG + K +QYFG Sbjct: 77 TRSESEALILENNFIKALSPKYNILFRDDKSYPYLMLSGHQYPQMAYYRGTLKKPNQYFG 136 Query: 125 PFPNAGAVKESIQILQKVFLLRTCEDTVFTNRTRPCLLHQIHRCSGPCVNLVSREDYALD 184 P+PN+ AV++SIQ+LQKVF+LRTCED+VF +R RPCLL+QI RC+ PCV +S EDY Sbjct: 137 PYPNSNAVRDSIQVLQKVFMLRTCEDSVFEHRDRPCLLYQIKRCTAPCVGHISEEDYRDS 196 Query: 185 VENASKFLRGRQSEVMEALEQKMHAFAADLKFEQAAAVRDQIGSLSSVLHQQ---SMETV 241 V A+ FL G+ E+ L+ KM AA+L+FE+AA RDQI +L + Q S Sbjct: 197 VREAATFLNGKTDELTRTLQHKMQTAAANLQFEEAARYRDQIQALGIMQSNQFIDSKNPN 256 Query: 242 SDADIDIIAVTVQGGRACVNLAMVRGGRHLGDRAYFPTHVDDAMDTAEESIEVEVLKAFL 301 + DID++A+ V G CV+ +RGGRH+GD+++FP +D ++ E AF+ Sbjct: 257 NPNDIDLLALAVSDGLVCVHWVSIRGGRHVGDKSFFPDTKNDPEPNGQDYAE-----AFV 311 Query: 302 AQHYIDKFIPGSLIVGTEFDDPALMMALMEQCGHRITLTFQPQGQRRQWLEMAAKGAEIA 361 AQHY+ K P +I D AL AL + G ++ + G+R+ L+MA + A++A Sbjct: 312 AQHYLGKSKPDIIISNFPVPD-ALKEALEGEHGKQMQFVTKTIGERKVRLKMAEQNAQMA 370 Query: 362 LARLLSEQGSQQARTRALAEVLELEREDLDELRAECFDISHTQGEATQASCVVFHHHAMQ 421 +A+ +Q SQQ R LA++L ++ + L+ R ECFDISHTQGEAT ASCVV+ +Q Sbjct: 371 IAQRRLQQSSQQHRIDELAKILGMDSDGLN--RLECFDISHTQGEATIASCVVYDEQNIQ 428 Query: 422 NGEYRRYNINDITPGDDYAAMRQVLTRRYEKV----ANGEGV-MPDIVLIDGGKGQVEMA 476 +YRRYNI PGDDYAAMR+VLTRRY K+ ANGE V PD VLIDGGKGQ+ +A Sbjct: 429 PSQYRRYNITTAKPGDDYAAMREVLTRRYGKMQEAEANGETVKWPDAVLIDGGKGQIGVA 488 Query: 477 RQVLTELGLDISLIVGVAKGEGRKVGLETLVFADGRAPKELGKESAALMLIAQIRDEAHR 536 V ELGL I L VG+AKG RK G+E L+ L S AL L+ +RDE+HR Sbjct: 489 VSVWEELGLHIPL-VGIAKGPERKAGMEELILPFTGEVFRLPPNSPALHLLQTVRDESHR 547 Query: 537 FAITGMRAKRAKARQTSRLEEIEGIGAKRRQRLLVRFGGLRGVVDASVDDLASVEGISRQ 596 FAITG R KR KAR TS L +I G+G+KRRQ LL RFGGLRGV+ AS +DL VEGIS+ Sbjct: 548 FAITGHRKKRDKARVTSSLSDIPGVGSKRRQALLTRFGGLRGVIAASREDLEKVEGISKA 607 Query: 597 LAEEIYRQLH 606 LAE IY LH Sbjct: 608 LAETIYNHLH 617 >PA2585 [L] COG0322 Nuclease subunit of the excinuclease complex Pae Pseudomonas aeruginosa Length = 608 Score = 580 bits (1496), Expect = e-165, Method: Compositional matrix adjust. Identities = 306/600 (51%), Positives = 405/600 (67%), Gaps = 16/600 (2%) Query: 12 PGVYRYFDAEDNVLYVGKARDLKKRVSSYFQKTLTSPRIAMMVERIARLETTVTRSEAEA 71 PGVYR FDAE +LYVGKA+ LKKR++SYF+K+ +P+ A +V RIA++ETT+T +E EA Sbjct: 18 PGVYRMFDAEAKLLYVGKAKSLKKRLASYFRKSGLAPKTAALVARIAQVETTITANETEA 77 Query: 72 LLLENNLIKTLRPRFNILFRDDKSYPYLKITGH-AFPRMAYYRGAVDKRSQYFGPFPNAG 130 LLLE LIK RP +NIL RDDKSYP++ ++ +PR++ +RGA ++ +YFGP+P+AG Sbjct: 78 LLLEQTLIKEWRPPYNILLRDDKSYPFVFLSSEDEYPRLSLHRGAKKRKGRYFGPYPSAG 137 Query: 131 AVKESIQILQKVFLLRTCEDTVFTNRTRPCLLHQIHRCSGPCVNLVSREDYALDVENASK 190 A++ES+ +LQK FL+R CED+ F NRTRPCL +QI RC GPCV LVS E+YA DV ++ Sbjct: 138 AIRESLNLLQKAFLVRQCEDSYFRNRTRPCLQYQIKRCKGPCVGLVSPEEYAEDVRHSVM 197 Query: 191 FLRGRQSEVMEALEQKMHAFAADLKFEQAAAVRDQIGSLSSVLHQQSMETVSDADIDIIA 250 FL GR + + + L M A L FE+AA +RDQ+ L V QQSME + D+DI+A Sbjct: 198 FLEGRSNALADELNVGMEQAAMRLDFEKAAELRDQVAILRRVQDQQSMEG-GNGDVDIVA 256 Query: 251 VTVQGGRACVNLAMVRGGRHLGDRAYFPTHVDDAMDTAEESIEVEVLKAFLAQHYI---D 307 V G ACV+L VRGGR LG + +FP A E EVL AFL Q+Y+ + Sbjct: 257 AIVTPGGACVHLISVRGGRVLGSKNFFP-------QVAIEEEVGEVLLAFLGQYYLSHQE 309 Query: 308 KFIPGSLIVGTEFDD-PALMMALMEQCGHRITLTFQPQGQRRQWLEMAAKGAEIALARLL 366 + +P LIV +D P L+ A+ E G + ++++ +G R +W ++A AE AL L Sbjct: 310 RDLPAELIVNVTHEDFPVLVSAIAEARGRELEISYRVRGTRARWQQLAVTNAEQALGARL 369 Query: 367 SEQGSQQARTRALAEVLELEREDLDELRAECFDISHTQGEATQASCVVFHHHAMQNGEYR 426 + + AR ALAE L+L R ECFDISH+ GEAT ASCVVF +YR Sbjct: 370 ANRQHVAARFEALAEALDLAEPPQ---RLECFDISHSSGEATVASCVVFGPEGPLKSDYR 426 Query: 427 RYNINDITPGDDYAAMRQVLTRRYEKVANGEGVMPDIVLIDGGKGQVEMARQVLTELGLD 486 RYNI +T GDDYAAM Q LTRR+ ++ +GEG MPDI+L+DGGKGQ+ MA++VL EL + Sbjct: 427 RYNIEGVTAGDDYAAMHQALTRRFSRLKDGEGKMPDILLVDGGKGQLAMAQEVLQELAVA 486 Query: 487 ISLIVGVAKGEGRKVGLETLVFADGRAPKELGKESAALMLIAQIRDEAHRFAITGMRAKR 546 +++GVAKG RK GLETL D L +S AL LI QIRDEAHRFAITG RA+R Sbjct: 487 GLILLGVAKGVTRKPGLETLYLNDASHEFTLPADSPALHLIQQIRDEAHRFAITGHRARR 546 Query: 547 AKARQTSRLEEIEGIGAKRRQRLLVRFGGLRGVVDASVDDLASVEGISRQLAEEIYRQLH 606 KAR+TS LE++ G+G KRR+ LL FGGL+ + AS+D+LA GIS++LAE+IY LH Sbjct: 547 GKARRTSTLEDVPGVGPKRRRDLLKHFGGLQELSRASIDELAKAPGISKKLAEQIYAVLH 606 >XF2311 [L] COG0322 Nuclease subunit of the excinuclease complex Xfa Xylella fastidiosa 9a5c Length = 627 Score = 531 bits (1368), Expect = e-150, Method: Compositional matrix adjust. Identities = 282/606 (46%), Positives = 394/606 (65%), Gaps = 19/606 (3%) Query: 6 ARLPHLPGVYRYFDAEDNVLYVGKARDLKKRVSSYFQKTLTSPRIAMMVERIARLETTVT 65 A L PGVY + A+D +LYVGKA L+KRV+SYF T + R+ M+ ++ R++ T+T Sbjct: 22 AHLSMAPGVYCMYAADDTLLYVGKAGALRKRVASYFNGTPKNTRLTAMLAQVVRMDVTIT 81 Query: 66 RSEAEALLLENNLIKTLRPRFNILFRDDKSYPYLKITGHAFPRMAYYRGAVDKRSQYFGP 125 R+EAEALLLEN LIK+L PR+N+L RDDKSYPY+ +T A+PR+A +RG +YFGP Sbjct: 82 RNEAEALLLENQLIKSLAPRYNVLLRDDKSYPYVLLTREAWPRIALHRGPQIVPGRYFGP 141 Query: 126 FPNAGAVKESIQILQKVFLLRTCEDTVFTNRTRPCLLHQIHRCSGPCVNLVSREDYALDV 185 +P AV++ + ++ K+F LR+CED+VF NR+RPCL +QI RCS PCVN+V+ ++Y V Sbjct: 142 YPGVTAVRDMLNLIHKLFKLRSCEDSVFRNRSRPCLQYQIGRCSAPCVNVVTHDNYTEAV 201 Query: 186 ENASKFLRGRQSEVMEALEQKMHAFAADLKFEQAAAVRDQIGSLSSVLHQQSMETVSDAD 245 + FL G+ + E L Q M + L+FEQAA +RD + SL S+ ++Q ++ + AD Sbjct: 202 RRVTLFLEGKSDLLAEELIQAMQVASEHLEFEQAARLRDLLTSLRSMQNRQYVDGRA-AD 260 Query: 246 IDIIAVTVQGGRACVNLAMVRGGRHLGDRAYFPTHVDDAMDTAEESIEVEVLKAFLAQHY 305 +D++A G ACV L R GR+LG R +FP T E E+L AF++Q+Y Sbjct: 261 LDVLACAALSGHACVLLLSFRDGRNLGTRMFFP-------KTNGEERTAEILSAFVSQYY 313 Query: 306 IDKFIPGSLIVGTEFDDPALM-MALMEQCGHRITLTFQPQGQRRQWLEMAAKGAEIALAR 364 + P +++ E D L+ A H+I+L + +G+R ++E+A + A++AL+ Sbjct: 314 AEYPPPPEILLDQEIPDHTLLEAAFSRSSAHKISLRWNVRGERAGYVELAVRNAQVALST 373 Query: 365 LLSEQGSQQARTRALAEVLELEREDLDELRAECFDISHTQGEATQASCVVFHHHAMQNGE 424 L+ Q +Q+ R+ A+ ++L LE E + R ECFDISHT GEAT ASCVVF + Sbjct: 374 ELTSQRAQRVRSEAVRQLLGLE-EPIK--RVECFDISHTMGEATVASCVVFDAVGPVRSQ 430 Query: 425 YRRYNINDITPGDDYAAMRQVLTRRYEKVA--NGEGVMPDIVLIDGGKGQVEMARQVLTE 482 YRRYNI ITPGDDYAAMRQ + RR+ + + +G PD++ IDGG GQ+ A+ L Sbjct: 431 YRRYNITGITPGDDYAAMRQAIERRFRRAVEEDKQGERPDVLFIDGGAGQLAQAKMALNA 490 Query: 483 LGLDISLIVGVAKGEGRKVGLETLVFADGRAPKEL--GKESAALMLIAQIRDEAHRFAIT 540 +G++ L+VGV+KGE R+ G ETL+ DG +EL G S AL I Q+RDEAHRFAIT Sbjct: 491 VGVESVLLVGVSKGEERRAGHETLIMLDG---QELHPGAASPALQFIQQVRDEAHRFAIT 547 Query: 541 GMRAKRAKARQTSRLEEIEGIGAKRRQRLLVRFGGLRGVVDASVDDLASVEGISRQLAEE 600 G RA+R K R TS+LE+I GIG++RR LL FGGL GV A ++A VEGIS LA + Sbjct: 548 GHRARRQKTRMTSKLEDIPGIGSRRRANLLKHFGGLAGVKAAGQTEIARVEGISTALAAK 607 Query: 601 IYRQLH 606 IY LH Sbjct: 608 IYASLH 613