BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0028.0029.p (290 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA0494 [I] COG0439 Biotin carboxylase Pae Pseudomonas aeruginosa 457 e-128 NMB1861 [I] COG0439 Biotin carboxylase Nme Neisseria meningitidi... 300 2e-81 NMA0596 [I] COG0439 Biotin carboxylase NmA Neisseria meningitidi... 295 7e-80 VC0295 [I] COG0439 Biotin carboxylase Vch Vibrio cholerae 293 4e-79 XF0049 [I] COG0439 Biotin carboxylase Xfa Xylella fastidiosa 9a5c 291 1e-78 >PA0494 [I] COG0439 Biotin carboxylase Pae Pseudomonas aeruginosa Length = 458 Score = 457 bits (1175), Expect = e-128, Method: Compositional matrix adjust. Identities = 225/279 (80%), Positives = 244/279 (87%) Query: 4 DAAELAREFPLAQGEAQAAFGSGAVYLERFIRRARHIEVQILGDGERAVHLFERECSLQR 63 DA EL REFP+AQ EAQAAFGS AVYLERFIR+ARHIEVQILGDGERAVHLFERECSLQR Sbjct: 176 DADELRREFPIAQREAQAAFGSPAVYLERFIRQARHIEVQILGDGERAVHLFERECSLQR 235 Query: 64 RRQKVFEEAPSPALTPQQRQALCDSAVRLAARLRYRGAGTLEYLFDDESGEFFFIEMNTR 123 RRQKVFEEAPS AL QRQALC+SAVRLA L YRGAGTLEYLFD SGEFFFIEMNTR Sbjct: 236 RRQKVFEEAPSAALDGAQRQALCESAVRLAQSLGYRGAGTLEYLFDAHSGEFFFIEMNTR 295 Query: 124 IQVEHPVTEMITGIDLVQAMLRIAGGEPLGLQQSDIRMQGAALEMRINAEDPERNFFPCP 183 IQVEHPV+EM+TGIDLVQAMLRIA GE L +Q DIR+ GAALEMRINAEDP RNFFP P Sbjct: 296 IQVEHPVSEMVTGIDLVQAMLRIAAGEALPWRQEDIRLNGAALEMRINAEDPARNFFPSP 355 Query: 184 GTVAELQWPQGEGVRVESHLYAGYRIPPYYDSLLAKLVVHGKDRAQAIARAQAAVAATHI 243 GTV L+WPQGEGVRV+SHLY GYR+PPYYDSLLAKL+VHG+DR +A ARA+ A+ T + Sbjct: 356 GTVERLEWPQGEGVRVDSHLYPGYRVPPYYDSLLAKLIVHGRDRDEAFARARQALERTVL 415 Query: 244 TGMATTLPLHQWLLADARVQAARFDTGALESWLAERANA 282 GMATTLPLH+WLLADARVQAA+FDT LE+WLAER A Sbjct: 416 AGMATTLPLHRWLLADARVQAAQFDTATLETWLAERTAA 454 >NMB1861 [I] COG0439 Biotin carboxylase Nme Neisseria meningitidis MC58 Length = 453 Score = 300 bits (768), Expect = 2e-81, Method: Compositional matrix adjust. Identities = 143/274 (52%), Positives = 192/274 (70%), Gaps = 4/274 (1%) Query: 7 ELAREFPLAQGEAQAAFGSGAVYLERFIRRARHIEVQILGDGE-RAVHLFERECSLQRRR 65 +L + + + EA AAFG+ VY+ER+++R RH+E+Q++ D A++L ER+CSLQRR Sbjct: 177 DLLQSVEMTKAEAGAAFGNPMVYMERYLQRPRHVEIQVIADEHGNAIYLAERDCSLQRRH 236 Query: 66 QKVFEEAPSPALTPQQRQALCDSAVRLAARLRYRGAGTLEYLFDDESGEFFFIEMNTRIQ 125 QKV EEAP+P +T ++R + ++ R+ YRGAGT E+L++D GEFFFIEMNTR+Q Sbjct: 237 QKVIEEAPAPFITEKERAKIGNACADACKRIGYRGAGTFEFLYED--GEFFFIEMNTRVQ 294 Query: 126 VEHPVTEMITGIDLVQAMLRIAGGEPLGLQQSDIRMQGAALEMRINAEDPERNFFPCPGT 185 VEHPVTE+ITG+D+VQ LRIA G PL +Q DI+++G A E RINAEDP NF P PG Sbjct: 295 VEHPVTELITGVDIVQEQLRIAAGLPLQYKQKDIQVEGHAFECRINAEDP-YNFIPSPGL 353 Query: 186 VAELQWPQGEGVRVESHLYAGYRIPPYYDSLLAKLVVHGKDRAQAIARAQAAVAATHITG 245 + P G G+RV+SH+Y GYRIPPYYDSL+ K+ VHGK R QA+A+ + A+A +TG Sbjct: 354 IESCHLPGGFGIRVDSHIYQGYRIPPYYDSLIGKICVHGKTREQAMAKMRVALAELAVTG 413 Query: 246 MATTLPLHQWLLADARVQAARFDTGALESWLAER 279 + T PLH+ L ADA Q LE WL +R Sbjct: 414 IKTNTPLHRDLFADAGFQKGGVSIHYLEHWLEDR 447 >NMA0596 [I] COG0439 Biotin carboxylase NmA Neisseria meningitidis Z2491 Length = 453 Score = 295 bits (755), Expect = 7e-80, Method: Compositional matrix adjust. Identities = 143/274 (52%), Positives = 189/274 (68%), Gaps = 4/274 (1%) Query: 7 ELAREFPLAQGEAQAAFGSGAVYLERFIRRARHIEVQILGDGE-RAVHLFERECSLQRRR 65 +L + + + EA AAFG+ VY+ER+++R RH+E+Q++ D AV+L ER+CSLQRR Sbjct: 177 DLLQSVEMTKAEAGAAFGNPMVYMERYLQRPRHVEIQVIADEHGNAVYLAERDCSLQRRH 236 Query: 66 QKVFEEAPSPALTPQQRQALCDSAVRLAARLRYRGAGTLEYLFDDESGEFFFIEMNTRIQ 125 QKV EEAP+P +T ++R + + R+ YRGAGT E+L++D GEFFFIEMNTR+Q Sbjct: 237 QKVIEEAPAPFITEKERAKIGKACADACKRIGYRGAGTFEFLYED--GEFFFIEMNTRVQ 294 Query: 126 VEHPVTEMITGIDLVQAMLRIAGGEPLGLQQSDIRMQGAALEMRINAEDPERNFFPCPGT 185 VEHPVTE+ITG+D+VQ LRIA G PL +Q DI+++G A E RINAEDP NF P PG Sbjct: 295 VEHPVTELITGVDIVQEQLRIAAGLPLQYKQKDIQVEGHAFECRINAEDP-YNFIPSPGP 353 Query: 186 VAELQWPQGEGVRVESHLYAGYRIPPYYDSLLAKLVVHGKDRAQAIARAQAAVAATHITG 245 + P G G+RV+SH+Y GYRIPPYYDSL+ K+ V GKDR QA+A+ + A+A ITG Sbjct: 354 IESCHLPSGFGIRVDSHIYQGYRIPPYYDSLIGKVCVVGKDRDQAMAKMRVALAELAITG 413 Query: 246 MATTLPLHQWLLADARVQAARFDTGALESWLAER 279 + T PLH+ L D Q LE WL +R Sbjct: 414 IKTNTPLHRDLFNDPGFQKGGVSIHYLEHWLEDR 447 >VC0295 [I] COG0439 Biotin carboxylase Vch Vibrio cholerae Length = 447 Score = 293 bits (749), Expect = 4e-79, Method: Compositional matrix adjust. Identities = 136/275 (49%), Positives = 191/275 (69%), Gaps = 4/275 (1%) Query: 4 DAAELAREFPLAQGEAQAAFGSGAVYLERFIRRARHIEVQILGDGE-RAVHLFERECSLQ 62 + AEL + + + EA+AAF + VY+E+F+ RH+EVQ++ DG+ A+HL ER+CS+Q Sbjct: 174 NEAELTKSIQMTRAEAKAAFNNDMVYMEKFLENPRHVEVQVIADGQGNAIHLAERDCSMQ 233 Query: 63 RRRQKVFEEAPSPALTPQQRQALCDSAVRLAARLRYRGAGTLEYLFDDESGEFFFIEMNT 122 RR QKV EEAP+P +T + R+ + + R + YRGAGT E+L+ E+GEF+FIEMNT Sbjct: 234 RRHQKVVEEAPAPGITEEMRKFIGERCTRACIEIGYRGAGTFEFLY--ENGEFYFIEMNT 291 Query: 123 RIQVEHPVTEMITGIDLVQAMLRIAGGEPLGLQQSDIRMQGAALEMRINAEDPERNFFPC 182 RIQVEHPVTEMITG+DL++ LRIA G+PL +Q DI+++G A+E RINAEDPER F PC Sbjct: 292 RIQVEHPVTEMITGVDLIKEQLRIAAGQPLSFKQEDIKIRGHAVECRINAEDPER-FLPC 350 Query: 183 PGTVAELQWPQGEGVRVESHLYAGYRIPPYYDSLLAKLVVHGKDRAQAIARAQAAVAATH 242 PG + P G GVR ESH+Y+GY +P +YDS++ KL+ +G++R AIAR + A+ Sbjct: 351 PGKIERFHAPGGMGVRWESHIYSGYTVPAHYDSMIGKLITYGENRDVAIARMRNALNEMI 410 Query: 243 ITGMATTLPLHQWLLADARVQAARFDTGALESWLA 277 + G+ T +PL Q ++AD Q + LE L Sbjct: 411 VEGIKTNIPLQQAIMADENFQKGGTNIHYLEKKLG 445 >XF0049 [I] COG0439 Biotin carboxylase Xfa Xylella fastidiosa 9a5c Length = 469 Score = 291 bits (744), Expect = 1e-78, Method: Compositional matrix adjust. Identities = 140/267 (52%), Positives = 185/267 (69%), Gaps = 4/267 (1%) Query: 16 QGEAQAAFGSGAVYLERFIRRARHIEVQILGDGE-RAVHLFERECSLQRRRQKVFEEAPS 74 Q EA+AAFG+G VY+E+F+ RH+E+Q+L DG+ A+HL ER+CS+QRR QKV EEAP+ Sbjct: 200 QSEAKAAFGNGQVYMEKFLENPRHVEIQVLADGQGNAIHLGERDCSMQRRHQKVVEEAPA 259 Query: 75 PALTPQQRQALCDSAVRLAARLRYRGAGTLEYLFDDESGEFFFIEMNTRIQVEHPVTEMI 134 P +T R + V R+ YRGAGT E+LF E+G F+FIEMNTRIQVEHPVTE I Sbjct: 260 PGITEALRNEIGQVCVDACIRIGYRGAGTFEFLF--ENGRFYFIEMNTRIQVEHPVTERI 317 Query: 135 TGIDLVQAMLRIAGGEPLGLQQSDIRMQGAALEMRINAEDPERNFFPCPGTVAELQWPQG 194 TGIDLV LRIA G+PL ++QSD+ ++G A+E RINAED E F P PG + P G Sbjct: 318 TGIDLVCEQLRIAAGQPLSIKQSDVVLRGHAIECRINAEDAE-TFLPNPGLITAFHPPGG 376 Query: 195 EGVRVESHLYAGYRIPPYYDSLLAKLVVHGKDRAQAIARAQAAVAATHITGMATTLPLHQ 254 GVR+++H+Y+GY++PP YDS++ KL+VHG DR AIAR A++ + G+ T +PL Q Sbjct: 377 PGVRMDTHIYSGYKVPPNYDSMIGKLIVHGPDRETAIARMHLALSEMVVDGIKTNIPLQQ 436 Query: 255 WLLADARVQAARFDTGALESWLAERAN 281 ++ D Q + LE LAER N Sbjct: 437 RIMCDKGFQFGGQNIHYLEKCLAERKN 463