BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0027.0113.p (253 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0020 [G] COG3622 Hydroxypyruvate isomerase Rso Ralstonia sola... 340 1e-93 PA0550 [G] COG3622 Hydroxypyruvate isomerase Pae Pseudomonas aer... 330 2e-90 mlr0252 Non COG 272 6e-73 PA1501 [G] COG3622 Hydroxypyruvate isomerase Pae Pseudomonas aer... 271 1e-72 BMEII1092 [G] COG3622 Hydroxypyruvate isomerase Bme Brucella mel... 259 4e-69 >RSc0020 [G] COG3622 Hydroxypyruvate isomerase Rso Ralstonia solanacearum Length = 262 Score = 340 bits (873), Expect = 1e-93, Method: Compositional matrix adjust. Identities = 166/255 (65%), Positives = 196/255 (76%), Gaps = 14/255 (5%) Query: 1 MLRFAANLSMMYVEHDFLDRFAAAAKDGFSGVEFLFPYDYQPEEIKSRLEANGLTQALFN 60 M RFAANL+MMY EH FLDRF AAA+DGF GVEFLFPYDY E+++RL+ NGL QALFN Sbjct: 1 MPRFAANLTMMYPEHAFLDRFTAAARDGFEGVEFLFPYDYDKTELRTRLDDNGLAQALFN 60 Query: 61 APPGDWAAGERGIASLPGREDEFKRSIETALKYASVIGNKTLHVMAGLIKPDQDRARHRA 120 APPGDWA GERGIASLPGREDEFKR I TAL YA +GN +HV+AGLI P DRARH A Sbjct: 61 APPGDWAGGERGIASLPGREDEFKRGIATALDYAQALGNTRVHVVAGLIGPHDDRARHHA 120 Query: 121 VYLDNLSYAAHQAESAGLTVVIEPINTRNIPGFFLNRQD--------------KSXFDCY 166 Y+ NL++AA +A SAG+T+V+EPINTR++PGFFL Q K FD Y Sbjct: 121 TYVQNLAHAAREAASAGITIVLEPINTRDMPGFFLTHQAQAHAVCREVGAPNLKVQFDLY 180 Query: 167 HCQIVEGDVAVKLKRDMPGIGHIQIAGVPERHEPDVGELNYPYLLKLIDSLGYQGWIGCE 226 H QI+EGD++VKL+ + GIGH+QIAGVP+RHEPD GELNYP+L L+D+LGY+GW+GCE Sbjct: 181 HAQIMEGDLSVKLREYLDGIGHVQIAGVPDRHEPDEGELNYPHLFALMDALGYRGWVGCE 240 Query: 227 YNPAGATSAGLGWLK 241 Y P TS GLGW K Sbjct: 241 YRPRAGTSEGLGWFK 255 >PA0550 [G] COG3622 Hydroxypyruvate isomerase Pae Pseudomonas aeruginosa Length = 265 Score = 330 bits (846), Expect = 2e-90, Method: Compositional matrix adjust. Identities = 163/256 (63%), Positives = 194/256 (75%), Gaps = 15/256 (5%) Query: 1 MLRFAANLSMMYVEHDFLDRFAAAAKDGFSGVEFLFPYDYQPEEIKSRLEANGLTQALFN 60 M RFAANLSM+Y HDFL+RFAAAA DGF GVE+LFPY Y E+K+RL+ +GL Q LFN Sbjct: 1 MPRFAANLSMLYPRHDFLERFAAAAADGFEGVEYLFPYAYPAAELKARLDDHGLRQVLFN 60 Query: 61 APPGDWAAGERGIASLPGREDEFKRSIETALKYASVIGNKTLHVMAGLIKPDQDRARHRA 120 A PGDW GERG+ASLPGRE EF+R+I A+ YA V+GN+ +HVMAGL+ DR RHR Sbjct: 61 AAPGDWDKGERGLASLPGREAEFRRAIAQAIDYAQVLGNRHIHVMAGLLPAGADRIRHRE 120 Query: 121 VYLDNLSYAAHQAESAGLTVVIEPINTRNIPGFFLNRQDKS--------------XFDCY 166 YLDNL++AA +A AGLTV+IEPIN R++PGFFL RQD + FDCY Sbjct: 121 TYLDNLAHAAREAAGAGLTVLIEPINNRDMPGFFLTRQDDAQAICREVGADNLQVQFDCY 180 Query: 167 HCQIVEGDVAVKLKRDMPGIGHIQIAGVPERHEP-DVGELNYPYLLKLIDSLGYQGWIGC 225 HCQIVEGD+A L+RD+ IGH+QIAGVP+RHEP D E+NYPYL +L+D LGYQGWIGC Sbjct: 181 HCQIVEGDLATTLRRDIGNIGHVQIAGVPDRHEPDDDNEVNYPYLFELLDRLGYQGWIGC 240 Query: 226 EYNPAGATSAGLGWLK 241 EY P G TSAGL WL+ Sbjct: 241 EYRPRGDTSAGLEWLR 256 >mlr0252 Non COG Length = 265 Score = 272 bits (695), Expect = 6e-73, Method: Compositional matrix adjust. Identities = 131/261 (50%), Positives = 173/261 (66%), Gaps = 14/261 (5%) Query: 1 MLRFAANLSMMYVEHDFLDRFAAAAKDGFSGVEFLFPYDYQPEEIKSRLEANGLTQALFN 60 M RF+ANLSM++ EHDFLDRF AAA+ GF GVE++ PYD+ PE + +RL+ NGLTQ LFN Sbjct: 1 MPRFSANLSMLFAEHDFLDRFDAAARAGFKGVEYIGPYDHAPEVVAARLKKNGLTQVLFN 60 Query: 61 APPGDWAAGERGIASLPGREDEFKRSIETALKYASVIGNKTLHVMAGLIKPDQDRARHRA 120 P GDW GERGIA LP R EF++ I A+ YA +G + ++ +AG+ DR Sbjct: 61 LPAGDWGKGERGIAVLPDRVPEFRQGIAKAITYAQALGCQQVNCLAGIAPAGVDRKVLED 120 Query: 121 VYLDNLSYAAHQAESAGLTVVIEPINTRNIPGFFLNRQDKS--------------XFDCY 166 V+ +NL++AA + E G+ ++IEPINTR+IPGFFLN D++ +D Y Sbjct: 121 VFAENLAFAAEKLERVGIRLLIEPINTRDIPGFFLNYSDQALALIDRVGSKNLFLQYDIY 180 Query: 167 HCQIVEGDVAVKLKRDMPGIGHIQIAGVPERHEPDVGELNYPYLLKLIDSLGYQGWIGCE 226 H QI+EGD+A K++ ++ I HIQ+A P RHEP GE+NYP+L ID +GY GWIG E Sbjct: 181 HMQIMEGDLARKIEANLGRIAHIQLADNPGRHEPGTGEINYPFLYDHIDRIGYAGWIGAE 240 Query: 227 YNPAGATSAGLGWLKALAEQG 247 Y P T AGLGW + L QG Sbjct: 241 YKPKAGTEAGLGWFRDLTGQG 261 >PA1501 [G] COG3622 Hydroxypyruvate isomerase Pae Pseudomonas aeruginosa Length = 260 Score = 271 bits (693), Expect = 1e-72, Method: Compositional matrix adjust. Identities = 130/256 (50%), Positives = 171/256 (66%), Gaps = 14/256 (5%) Query: 1 MLRFAANLSMMYVEHDFLDRFAAAAKDGFSGVEFLFPYDYQPEEIKSRLEANGLTQALFN 60 M RF ANLSM++ E DFL+RF AAAK GF+GVE+LFPYD + E IK+RLEANGL Q LFN Sbjct: 1 MPRFCANLSMLFTEVDFLERFDAAAKAGFAGVEYLFPYDVEAEAIKARLEANGLEQVLFN 60 Query: 61 APPGDWAAGERGIASLPGREDEFKRSIETALKYASVIGNKTLHVMAGLIKPDQDRARHRA 120 P GDWA GERGIA P R EF+ ++ A+ YA V+GN+ ++ +AG+ D A Sbjct: 61 LPAGDWAKGERGIACHPDRVQEFREGVDKAIAYARVLGNRQVNCLAGIRPQGHDCASVEK 120 Query: 121 VYLDNLSYAAHQAESAGLTVVIEPINTRNIPGFFLNRQDKS--------------XFDCY 166 ++DNL YAA + E+AG+ +V+E INT +IPGF+L ++ +D Y Sbjct: 121 TFVDNLRYAADKLEAAGIRLVMEMINTLDIPGFYLQNTRQALEIRDKVGSANLFLQYDIY 180 Query: 167 HCQIVEGDVAVKLKRDMPGIGHIQIAGVPERHEPDVGELNYPYLLKLIDSLGYQGWIGCE 226 H QI+EGD+A L+ + I H+Q+A P RHEP GE+NY +L + +D +GYQGWIGCE Sbjct: 181 HMQIMEGDLARTLENQLAAINHVQLADNPGRHEPGTGEINYRFLFEHLDRIGYQGWIGCE 240 Query: 227 YNPAGATSAGLGWLKA 242 Y PA T AGLGW+K Sbjct: 241 YKPATTTEAGLGWMKT 256 >BMEII1092 [G] COG3622 Hydroxypyruvate isomerase Bme Brucella melitensis Length = 261 Score = 259 bits (662), Expect = 4e-69, Method: Compositional matrix adjust. Identities = 124/260 (47%), Positives = 170/260 (65%), Gaps = 15/260 (5%) Query: 1 MLRFAANLSMMYVEHDFLDRFAAAAKDGFSGVEFLFPYDYQPEEIKSRLEANGLTQALFN 60 M RFAANLS M+ E FL+RF AA+ GF GVEFLFPYD+ + I L+ + LTQ LFN Sbjct: 1 MPRFAANLSTMFNEVPFLERFRLAAEAGFGGVEFLFPYDFDADVIARELKQHNLTQVLFN 60 Query: 61 APPGDWAAGERGIASLPGREDEFKRSIETALKYASVIGNKTLHVMAGLIKPDQDRARHRA 120 PPGDWAAGERG+A++ GRE EF+ +++ AL YA + +TLH M+G I DR Sbjct: 61 MPPGDWAAGERGMAAISGREQEFRDNVDIALHYALALDCRTLHAMSG-ITEGLDRKACEE 119 Query: 121 VYLDNLSYAAHQAESAGLTVVIEPINTRNIPGFFLNRQDKS--------------XFDCY 166 +++N YAA + G+TV++EP+NTRN+PG+F+ Q ++ D Y Sbjct: 120 TFIENFRYAADKLAPHGITVLVEPLNTRNMPGYFIVHQLEAVGLVKRVNRPNVAVQLDLY 179 Query: 167 HCQIVEGDVAVKLKRDMPGIGHIQIAGVPERHEPDVGELNYPYLLKLIDSLGYQGWIGCE 226 H QI++GD+ +++ H+QIA VP+RHEPD GELNYPYL +++S+GY+GW+GCE Sbjct: 180 HAQIMDGDLTRLIEKMNGAFSHVQIASVPDRHEPDEGELNYPYLFSVLESVGYRGWVGCE 239 Query: 227 YNPAGATSAGLGWLKALAEQ 246 YNP G T +GL W +Q Sbjct: 240 YNPRGKTESGLAWFAPYRDQ 259