BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0027.0063.p (355 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2901 [J] COG0216 Protein chain release factor A Rso Ralstonia... 576 e-164 NMB1686 [J] COG0216 Protein chain release factor A Nme Neisseria... 563 e-160 NMA1945 [J] COG0216 Protein chain release factor A NmA Neisseria... 561 e-159 HI1561 [J] COG0216 Protein chain release factor A Hin Haemophilu... 468 e-132 PM0555 [J] COG0216 Protein chain release factor A Pmu Pasteurell... 468 e-131 >RSc2901 [J] COG0216 Protein chain release factor A Rso Ralstonia solanacearum Length = 360 Score = 576 bits (1485), Expect = e-164, Method: Compositional matrix adjust. Identities = 276/355 (77%), Positives = 315/355 (88%) Query: 1 MLAKLDQLAERLEELNSLLAQEDATSSMDNFRKMTREHAELGPLVALYHDYVQASEDIRT 60 ML+KLDQLAER E+N+LLA+EDAT+++D +RK+TREHAEL P+VA Y + QA +D+ T Sbjct: 5 MLSKLDQLAERTVEINALLAREDATANLDQYRKLTREHAELEPVVAQYAAWKQAEDDVTT 64 Query: 61 AGELLSDPDMKAFAQEEIDGAKARMEALELDLQKMLLPKDPNDERNIFLEIRAGTGGDES 120 A ELL+DPDMKAFA++EI A+ RM LE +LQ++LLPKDPND RNIFLEIRAGTGGDES Sbjct: 65 AQELLADPDMKAFAEDEIRAARERMTTLEAELQRLLLPKDPNDHRNIFLEIRAGTGGDES 124 Query: 121 ALFAGDLLRMYTRYAERQRWQVEIVSASESELGGYKEVIARIAGFGAYSRLKFESGGHRV 180 ALFAGDLLRMYTRYAERQRWQVEIVS S S+LGGYKEVI R+ G GAYSRLKFESGGHRV Sbjct: 125 ALFAGDLLRMYTRYAERQRWQVEIVSESASDLGGYKEVIVRLVGEGAYSRLKFESGGHRV 184 Query: 181 QRVPATETQGRIHTSACTVAVMPEADEVEDVDINPADLRIDTYRASGAGGQHINKTDSAV 240 QRVPATE QGRIHTSACTVAVMPEAD + D+ INPADLRIDT+RASGAGGQHINKTDSAV Sbjct: 185 QRVPATEAQGRIHTSACTVAVMPEADPLADIQINPADLRIDTFRASGAGGQHINKTDSAV 244 Query: 241 RITHLPTGIVVECQDDRSQHKNKAQAMKVLAARIKDVQLREQQSKEAATRKSLIGSGDRS 300 R+THLPTG+VVECQDDRSQH+NK +AM+VLAAR+KD Q RE Q+KEA+ RKSLIGSGDRS Sbjct: 245 RLTHLPTGLVVECQDDRSQHRNKDRAMQVLAARLKDRQEREAQAKEASARKSLIGSGDRS 304 Query: 301 ERIRTYNFPQGRMTDHRINLTLYKLDFIMDGDLDELTNALITEHQAELLAQLGDD 355 +RIRTYNFPQGR+TDHRINLTLYK+D +MDGDL EL AL EHQAE LA LG++ Sbjct: 305 DRIRTYNFPQGRITDHRINLTLYKIDALMDGDLGELLGALAAEHQAEQLAALGEE 359 >NMB1686 [J] COG0216 Protein chain release factor A Nme Neisseria meningitidis MC58 Length = 358 Score = 563 bits (1451), Expect = e-160, Method: Compositional matrix adjust. Identities = 275/354 (77%), Positives = 318/354 (89%) Query: 1 MLAKLDQLAERLEELNSLLAQEDATSSMDNFRKMTREHAELGPLVALYHDYVQASEDIRT 60 +L KL QL++RLEE+ LL Q +ATS MDN+RK+TREHAEL P+V ++ +Y A D+ Sbjct: 5 ILEKLQQLSDRLEEVTHLLGQPEATSDMDNYRKLTREHAELTPVVEVFQNYRLAQSDLAD 64 Query: 61 AGELLSDPDMKAFAQEEIDGAKARMEALELDLQKMLLPKDPNDERNIFLEIRAGTGGDES 120 A E+LSDP+MK FA EEI+ AKA++ L+ +LQK+LLPKD +D++NIF+EIRAGTGGDE+ Sbjct: 65 AEEMLSDPEMKDFAAEEIEAAKAKIGELDTELQKLLLPKDADDDKNIFIEIRAGTGGDEA 124 Query: 121 ALFAGDLLRMYTRYAERQRWQVEIVSASESELGGYKEVIARIAGFGAYSRLKFESGGHRV 180 ALFAGDLLRMY+RYAER RWQVEIVSA+ESELGGYKEVIARI G GAYSRLKFESGGHRV Sbjct: 125 ALFAGDLLRMYSRYAERNRWQVEIVSANESELGGYKEVIARIVGLGAYSRLKFESGGHRV 184 Query: 181 QRVPATETQGRIHTSACTVAVMPEADEVEDVDINPADLRIDTYRASGAGGQHINKTDSAV 240 QRVPATE+QGRIHTSACTVAVMPEADE+ED+++NPADLRIDT+RASGAGGQHINKTDSAV Sbjct: 185 QRVPATESQGRIHTSACTVAVMPEADELEDIELNPADLRIDTFRASGAGGQHINKTDSAV 244 Query: 241 RITHLPTGIVVECQDDRSQHKNKAQAMKVLAARIKDVQLREQQSKEAATRKSLIGSGDRS 300 RITHLPTG+VVECQD RSQH NKAQAMKVLAAR+ D Q RE Q+KEAA RKSLIGSGDRS Sbjct: 245 RITHLPTGMVVECQDGRSQHANKAQAMKVLAARLNDAQKREAQAKEAAERKSLIGSGDRS 304 Query: 301 ERIRTYNFPQGRMTDHRINLTLYKLDFIMDGDLDELTNALITEHQAELLAQLGD 354 ERIRTYN+PQGR+TDHRINLTL+KLDF+MDGDL+E+TNALI EHQAELLA +GD Sbjct: 305 ERIRTYNYPQGRVTDHRINLTLHKLDFVMDGDLEEITNALIAEHQAELLAAMGD 358 >NMA1945 [J] COG0216 Protein chain release factor A NmA Neisseria meningitidis Z2491 Length = 358 Score = 561 bits (1445), Expect = e-159, Method: Compositional matrix adjust. Identities = 275/354 (77%), Positives = 316/354 (89%) Query: 1 MLAKLDQLAERLEELNSLLAQEDATSSMDNFRKMTREHAELGPLVALYHDYVQASEDIRT 60 +L KL QL +RLEE+ LL Q +ATS MDN+RK+TREHAEL P+V ++ +Y A D+ Sbjct: 5 ILEKLQQLGDRLEEVTHLLGQPEATSDMDNYRKLTREHAELTPVVEVFQNYRLAQSDLAD 64 Query: 61 AGELLSDPDMKAFAQEEIDGAKARMEALELDLQKMLLPKDPNDERNIFLEIRAGTGGDES 120 A E+LSDP+MK FA EEI+ AKA++ L+ +LQK+LLPKD +D++NIF+EIRAGTGGDE+ Sbjct: 65 AEEMLSDPEMKDFAAEEIEAAKAKIGELDTELQKLLLPKDADDDKNIFIEIRAGTGGDEA 124 Query: 121 ALFAGDLLRMYTRYAERQRWQVEIVSASESELGGYKEVIARIAGFGAYSRLKFESGGHRV 180 ALFAGDLLRMY+RYAER RWQVEIVSA+ESELGGYKEVIARI G GAYSRLKFESGGHRV Sbjct: 125 ALFAGDLLRMYSRYAERNRWQVEIVSANESELGGYKEVIARIIGLGAYSRLKFESGGHRV 184 Query: 181 QRVPATETQGRIHTSACTVAVMPEADEVEDVDINPADLRIDTYRASGAGGQHINKTDSAV 240 QRVPATE+QGRIHTSACTVAVMPEADE+ED+++NPADLRIDT+RASGAGGQHINKTDSAV Sbjct: 185 QRVPATESQGRIHTSACTVAVMPEADELEDIELNPADLRIDTFRASGAGGQHINKTDSAV 244 Query: 241 RITHLPTGIVVECQDDRSQHKNKAQAMKVLAARIKDVQLREQQSKEAATRKSLIGSGDRS 300 RITHLPTG+VVECQD RSQH NKAQAMKVLAAR+ D Q RE Q+KEAA RKSLIGSGDRS Sbjct: 245 RITHLPTGMVVECQDGRSQHANKAQAMKVLAARLNDAQKREAQAKEAAERKSLIGSGDRS 304 Query: 301 ERIRTYNFPQGRMTDHRINLTLYKLDFIMDGDLDELTNALITEHQAELLAQLGD 354 ERIRTYN+PQGR+TDHRINLTL+KLDF+MDGDL E+TNALI EHQAELLA +GD Sbjct: 305 ERIRTYNYPQGRVTDHRINLTLHKLDFVMDGDLAEITNALIAEHQAELLAAMGD 358 >HI1561 [J] COG0216 Protein chain release factor A Hin Haemophilus influenzae Length = 361 Score = 468 bits (1205), Expect = e-132, Method: Compositional matrix adjust. Identities = 219/354 (61%), Positives = 281/354 (79%) Query: 1 MLAKLDQLAERLEELNSLLAQEDATSSMDNFRKMTREHAELGPLVALYHDYVQASEDIRT 60 ++AKL+ L ER EEL +LL S D FR ++E+++L +V ++ + Q +++I Sbjct: 6 IIAKLESLKERYEELEALLGDVSVISDQDKFRAYSKEYSQLEEVVKCFNRWTQLNQNIEE 65 Query: 61 AGELLSDPDMKAFAQEEIDGAKARMEALELDLQKMLLPKDPNDERNIFLEIRAGTGGDES 120 A LL DP+MK AQ EI+ +KA +E +E LQ +LLPKDPNDE N +LEIRAGTGGDE+ Sbjct: 66 AEILLDDPEMKEMAQMEIEESKAEIEEVEQQLQILLLPKDPNDEYNCYLEIRAGTGGDEA 125 Query: 121 ALFAGDLLRMYTRYAERQRWQVEIVSASESELGGYKEVIARIAGFGAYSRLKFESGGHRV 180 +FAGDL RMY+RYAE +RW+VE++SA+ESE GGYKEVI ++ G G Y +LKFESGGHRV Sbjct: 126 GIFAGDLFRMYSRYAESKRWRVEMLSANESEQGGYKEVIVKVTGEGVYGQLKFESGGHRV 185 Query: 181 QRVPATETQGRIHTSACTVAVMPEADEVEDVDINPADLRIDTYRASGAGGQHINKTDSAV 240 QRVP TE+QGRIHTSACTVAVMPE E E +INPADLRIDTYR+SGAGGQH+N TDSAV Sbjct: 186 QRVPKTESQGRIHTSACTVAVMPELPESEMPEINPADLRIDTYRSSGAGGQHVNTTDSAV 245 Query: 241 RITHLPTGIVVECQDDRSQHKNKAQAMKVLAARIKDVQLREQQSKEAATRKSLIGSGDRS 300 RITH+PTGIVVECQD+RSQHKNKA+AM VLA+RI + Q +++ R++L+GSGDRS Sbjct: 246 RITHIPTGIVVECQDERSQHKNKAKAMSVLASRIVQAEQERQAAEQTDMRRNLLGSGDRS 305 Query: 301 ERIRTYNFPQGRMTDHRINLTLYKLDFIMDGDLDELTNALITEHQAELLAQLGD 354 ++IRTYN+PQGR+TDHRINLT+Y+LD +M+G +DEL +ITE+QA+ LA L + Sbjct: 306 DKIRTYNYPQGRVTDHRINLTIYRLDEVMNGKIDELIQPIITEYQADQLAALSE 359 >PM0555 [J] COG0216 Protein chain release factor A Pmu Pasteurella multocida Length = 360 Score = 468 bits (1204), Expect = e-131, Method: Compositional matrix adjust. Identities = 218/354 (61%), Positives = 279/354 (78%) Query: 1 MLAKLDQLAERLEELNSLLAQEDATSSMDNFRKMTREHAELGPLVALYHDYVQASEDIRT 60 +++KL+ L ER EEL +LL + S D FR ++E+A+L +V + + Q + ++ Sbjct: 5 IISKLESLKERHEELEALLGEASVISDQDKFRAYSKEYAQLEDVVKCFARWNQLNSNMEE 64 Query: 61 AGELLSDPDMKAFAQEEIDGAKARMEALELDLQKMLLPKDPNDERNIFLEIRAGTGGDES 120 A LL DP MK AQEEI+ K +E +E LQ +LLPKDPNDE N +LEIRAGTGGDE+ Sbjct: 65 AQLLLDDPSMKEMAQEEIEACKTEIEQVEQQLQILLLPKDPNDEYNCYLEIRAGTGGDEA 124 Query: 121 ALFAGDLLRMYTRYAERQRWQVEIVSASESELGGYKEVIARIAGFGAYSRLKFESGGHRV 180 +FAGDL RMY+RYAE +RW+VE++SA+ESE GGYKE+I ++ G G Y +LKFESGGHRV Sbjct: 125 GIFAGDLFRMYSRYAESKRWKVEVLSANESEQGGYKEIIVKVNGEGVYGQLKFESGGHRV 184 Query: 181 QRVPATETQGRIHTSACTVAVMPEADEVEDVDINPADLRIDTYRASGAGGQHINKTDSAV 240 QRVP TE+QGRIHTSACTVAVMPE E E +INP+DLRIDTYR+SGAGGQH+N TDSAV Sbjct: 185 QRVPKTESQGRIHTSACTVAVMPELPESELPEINPSDLRIDTYRSSGAGGQHVNTTDSAV 244 Query: 241 RITHLPTGIVVECQDDRSQHKNKAQAMKVLAARIKDVQLREQQSKEAATRKSLIGSGDRS 300 RITH+PTGIVVECQD+RSQHKNKA+AM VLA+RI + Q+ +A TR++L+GSGDRS Sbjct: 245 RITHIPTGIVVECQDERSQHKNKAKAMSVLASRIVQAEKERQEQAQADTRRNLLGSGDRS 304 Query: 301 ERIRTYNFPQGRMTDHRINLTLYKLDFIMDGDLDELTNALITEHQAELLAQLGD 354 ++IRTYN+PQGR+TDHRINLT+Y+LD +M+G +DEL +ITE+QA+ LA L + Sbjct: 305 DKIRTYNYPQGRVTDHRINLTVYRLDEVMNGKIDELIQPIITEYQADQLAALSE 358