BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0027.0016.p (300 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA5382 [K] COG0583 Transcriptional regulator Pae Pseudomonas aer... 305 1e-82 YPO1308 [K] COG0583 Transcriptional regulator Ype Yersinia pestis 282 6e-76 yeiE [K] COG0583 Transcriptional regulator Eco Escherichia coli K12 272 7e-73 ZyeiE [K] COG0583 Transcriptional regulator EcZ Escherichia coli... 272 7e-73 ECs3049 [K] COG0583 Transcriptional regulator Ecs Escherichia co... 272 7e-73 >PA5382 [K] COG0583 Transcriptional regulator Pae Pseudomonas aeruginosa Length = 297 Score = 305 bits (780), Expect = 1e-82, Method: Compositional matrix adjust. Identities = 159/292 (54%), Positives = 203/292 (69%), Gaps = 2/292 (0%) Query: 1 MRITLRQLQIFLAVAQSGSTTAAAGLVALSQSAASAALNELESLLGVQLFDRVGKRLVLN 60 M ++ RQLQIF AVA+ GSTTAAA ++LSQSA SAALNELES L +LFDRVGKRL LN Sbjct: 1 MALSFRQLQIFCAVARCGSTTAAAESISLSQSATSAALNELESQLSTRLFDRVGKRLQLN 60 Query: 61 DSGRQLLPQARHMLDAAQTIERQFSDPAA-GSDLHLGASTTIGSYLLPAMIAAYRRSHAG 119 + GR+ LPQA +LD +E+QF+ AA + L + AS+TIG+Y+LP ++A++ R G Sbjct: 61 EVGRRFLPQALRLLDGVAQLEQQFAVSAAPQASLTVAASSTIGNYVLPRLLASFEREQPG 120 Query: 120 ARVRALVANTADIVEAVVNFEVDAGLIEGPCHADDVQVEPWMTDELIVVAAPKHPIVRAR 179 RV A + NT V+ VV F D GLIEGPCH ++VEPW+ D LIVVAAP HP+ +R Sbjct: 121 VRVNASIGNTGSAVQDVVTFAADIGLIEGPCHEPGLRVEPWLEDSLIVVAAPGHPLA-SR 179 Query: 180 RKITLKMLREADWLLREAGSGTREAVEHALIPYLHHLPSSFEFGNSEAIKRATAEGLGIS 239 +++ + LR A WLLRE GSGTRE V HAL+ +LH+L S + G+SEAIK + A GLGIS Sbjct: 180 TQVSREALRRARWLLREPGSGTREEVSHALLGHLHYLEDSLDLGSSEAIKHSVAAGLGIS 239 Query: 240 CLSRSVVEDLIESRKLVELDTPLPTLRRHFYMVVSRHRAPSPSLSALLSFCR 291 CLSR VVE+ + + LVEL + LP LRR FYM+ R + SP CR Sbjct: 240 CLSRWVVEEQLATGALVELRSSLPPLRRRFYMLRQRDKFLSPGFERFWEHCR 291 >YPO1308 [K] COG0583 Transcriptional regulator Ype Yersinia pestis Length = 290 Score = 282 bits (722), Expect = 6e-76, Method: Compositional matrix adjust. Identities = 150/293 (51%), Positives = 197/293 (67%), Gaps = 6/293 (2%) Query: 1 MRITLRQLQIFLAVAQSGSTTAAAGLVALSQSAASAALNELESLLGVQLFDRVGKRLVLN 60 M ITLRQL++F V +SGSTT A+ ++ALSQSA SAAL +LE LGVQLFDRVGKRLV N Sbjct: 1 MHITLRQLEVFTEVLKSGSTTQASVVLALSQSAVSAALADLEGQLGVQLFDRVGKRLVTN 60 Query: 61 DSGRQLLPQARHMLDAAQTIERQF-SDPAAGSDLHLGASTTIGSYLLPAMIAAYRRSHAG 119 + GR L P+A +LD A IE+ F D A L + AS+TIG+Y+LP MIA YRR G Sbjct: 61 EHGRLLYPKALALLDQAIEIEQLFLHDLGA---LRIAASSTIGNYMLPGMIAKYRRDFPG 117 Query: 120 ARVRALVANTADIVEAVVNFEVDAGLIEGPCHADDVQVEPWMTDELIVVAAPKHPIVRAR 179 + + N+ D++EAV +F D GLIEGPCH ++ + W+ DEL+V AAP P+ Sbjct: 118 TPLELNIGNSQDVIEAVADFRGDLGLIEGPCHMPELVTQNWLRDELVVFAAPDSPL--CH 175 Query: 180 RKITLKMLREADWLLREAGSGTREAVEHALIPYLHHLPSSFEFGNSEAIKRATAEGLGIS 239 + +TL L +ADW+LRE GSGTRE ++H L+ L H E GNSEAIKRA G+G+S Sbjct: 176 KALTLVDLADADWILRERGSGTREVLDHLLLAQLPHFKLVMELGNSEAIKRAVRYGMGVS 235 Query: 240 CLSRSVVEDLIESRKLVELDTPLPTLRRHFYMVVSRHRAPSPSLSALLSFCRD 292 CLSR V+ D + S +LVEL+ PLP L R Y++ R + S +L LS+C++ Sbjct: 236 CLSRRVIADQLASGELVELNIPLPPLIRTLYLIHHRQKHISNALLRFLSYCQE 288 >yeiE [K] COG0583 Transcriptional regulator Eco Escherichia coli K12 Length = 293 Score = 272 bits (695), Expect = 7e-73, Method: Compositional matrix adjust. Identities = 143/290 (49%), Positives = 195/290 (67%), Gaps = 4/290 (1%) Query: 1 MRITLRQLQIFLAVAQSGSTTAAAGLVALSQSAASAALNELESLLGVQLFDRVGKRLVLN 60 M ITLRQL++F V +SGSTT A+ ++ALSQSA SAAL +LE LGVQLFDRVGKRLV+N Sbjct: 1 MHITLRQLEVFAEVLKSGSTTQASVMLALSQSAVSAALTDLEGQLGVQLFDRVGKRLVVN 60 Query: 61 DSGRQLLPQARHMLDAAQTIERQFSDPAAGSDLHLGASTTIGSYLLPAMIAAYRRSHAGA 120 + GR L P+A +L+ A IE+ F + + + AS+TIG+Y+LPA+IA YR + Sbjct: 61 EHGRLLYPRALALLEQAVEIEQLFREDNGA--IRIYASSTIGNYILPAVIARYRHDYPQL 118 Query: 121 RVRALVANTADIVEAVVNFEVDAGLIEGPCHADDVQVEPWMTDELIVVAAPKHPIVRARR 180 + V N+ D+++AV++F VD G IEGPCH+ ++ EPW+ DEL+V AAP P+ AR Sbjct: 119 PIELSVGNSQDVMQAVLDFRVDIGFIEGPCHSTEIISEPWLEDELVVFAAPTSPL--ARG 176 Query: 181 KITLKMLREADWLLREAGSGTREAVEHALIPYLHHLPSSFEFGNSEAIKRATAEGLGISC 240 +TL+ L A W+LRE GSGTRE V++ L+ +L + E GNSEAIK A GLGISC Sbjct: 177 PVTLEQLAAAPWILRERGSGTREIVDYLLLSHLPKFEMAMELGNSEAIKHAVRHGLGISC 236 Query: 241 LSRSVVEDLIESRKLVELDTPLPTLRRHFYMVVSRHRAPSPSLSALLSFC 290 LSR V+ED +++ L E+ PLP L R + + R + S +L L +C Sbjct: 237 LSRRVIEDQLQAGTLSEVAVPLPRLMRTLWRIHHRQKHLSNALRRFLDYC 286 >ZyeiE [K] COG0583 Transcriptional regulator EcZ Escherichia coli O157:H7 EDL933 Length = 293 Score = 272 bits (695), Expect = 7e-73, Method: Compositional matrix adjust. Identities = 143/290 (49%), Positives = 195/290 (67%), Gaps = 4/290 (1%) Query: 1 MRITLRQLQIFLAVAQSGSTTAAAGLVALSQSAASAALNELESLLGVQLFDRVGKRLVLN 60 M ITLRQL++F V +SGSTT A+ ++ALSQSA SAAL +LE LGVQLFDRVGKRLV+N Sbjct: 1 MHITLRQLEVFAEVLKSGSTTQASVMLALSQSAVSAALTDLEGQLGVQLFDRVGKRLVVN 60 Query: 61 DSGRQLLPQARHMLDAAQTIERQFSDPAAGSDLHLGASTTIGSYLLPAMIAAYRRSHAGA 120 + GR L P+A +L+ A IE+ F + + + AS+TIG+Y+LPA+IA YR + Sbjct: 61 EHGRLLYPRALALLEQAVEIEQLFREDNGA--IRIYASSTIGNYILPAVIARYRHDYPQL 118 Query: 121 RVRALVANTADIVEAVVNFEVDAGLIEGPCHADDVQVEPWMTDELIVVAAPKHPIVRARR 180 + V N+ D+++AV++F VD G IEGPCH+ ++ EPW+ DEL+V AAP P+ AR Sbjct: 119 PIELSVGNSQDVMQAVLDFRVDIGFIEGPCHSTEIISEPWLEDELVVFAAPTSPL--ARG 176 Query: 181 KITLKMLREADWLLREAGSGTREAVEHALIPYLHHLPSSFEFGNSEAIKRATAEGLGISC 240 +TL+ L A W+LRE GSGTRE V++ L+ +L + E GNSEAIK A GLGISC Sbjct: 177 PVTLEQLAAAPWILRERGSGTREIVDYLLLSHLPKFEMAMELGNSEAIKHAVRHGLGISC 236 Query: 241 LSRSVVEDLIESRKLVELDTPLPTLRRHFYMVVSRHRAPSPSLSALLSFC 290 LSR V+ED +++ L E+ PLP L R + + R + S +L L +C Sbjct: 237 LSRRVIEDQLQAGTLSEVAVPLPRLMRTLWRIHHRQKHLSNALRRFLDYC 286 >ECs3049 [K] COG0583 Transcriptional regulator Ecs Escherichia coli O157:H7 Length = 293 Score = 272 bits (695), Expect = 7e-73, Method: Compositional matrix adjust. Identities = 143/290 (49%), Positives = 195/290 (67%), Gaps = 4/290 (1%) Query: 1 MRITLRQLQIFLAVAQSGSTTAAAGLVALSQSAASAALNELESLLGVQLFDRVGKRLVLN 60 M ITLRQL++F V +SGSTT A+ ++ALSQSA SAAL +LE LGVQLFDRVGKRLV+N Sbjct: 1 MHITLRQLEVFAEVLKSGSTTQASVMLALSQSAVSAALTDLEGQLGVQLFDRVGKRLVVN 60 Query: 61 DSGRQLLPQARHMLDAAQTIERQFSDPAAGSDLHLGASTTIGSYLLPAMIAAYRRSHAGA 120 + GR L P+A +L+ A IE+ F + + + AS+TIG+Y+LPA+IA YR + Sbjct: 61 EHGRLLYPRALALLEQAVEIEQLFREDNGA--IRIYASSTIGNYILPAVIARYRHDYPQL 118 Query: 121 RVRALVANTADIVEAVVNFEVDAGLIEGPCHADDVQVEPWMTDELIVVAAPKHPIVRARR 180 + V N+ D+++AV++F VD G IEGPCH+ ++ EPW+ DEL+V AAP P+ AR Sbjct: 119 PIELSVGNSQDVMQAVLDFRVDIGFIEGPCHSTEIISEPWLEDELVVFAAPTSPL--ARG 176 Query: 181 KITLKMLREADWLLREAGSGTREAVEHALIPYLHHLPSSFEFGNSEAIKRATAEGLGISC 240 +TL+ L A W+LRE GSGTRE V++ L+ +L + E GNSEAIK A GLGISC Sbjct: 177 PVTLEQLAAAPWILRERGSGTREIVDYLLLSHLPKFEMAMELGNSEAIKHAVRHGLGISC 236 Query: 241 LSRSVVEDLIESRKLVELDTPLPTLRRHFYMVVSRHRAPSPSLSALLSFC 290 LSR V+ED +++ L E+ PLP L R + + R + S +L L +C Sbjct: 237 LSRRVIEDQLQAGTLSEVAVPLPRLMRTLWRIHHRQKHLSNALRRFLDYC 286