BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0026.0005.p (426 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value arsB [P] COG1055 Na+/H+ antiporter NhaD and related arsenite per... 602 e-172 ZarsB [P] COG1055 Na+/H+ antiporter NhaD and related arsenite pe... 602 e-172 ECs4374 [P] COG1055 Na+/H+ antiporter NhaD and related arsenite ... 602 e-172 YPO3347 [P] COG1055 Na+/H+ antiporter NhaD and related arsenite ... 580 e-165 PA2278 [P] COG1055 Na+/H+ antiporter NhaD and related arsenite p... 567 e-161 >arsB [P] COG1055 Na+/H+ antiporter NhaD and related arsenite permeases Eco Escherichia coli K12 Length = 436 Score = 602 bits (1553), Expect = e-172, Method: Compositional matrix adjust. Identities = 316/426 (74%), Positives = 363/426 (85%) Query: 1 MLAAFVIFLITLVLVIWQPKGLGIGWSACGGAAVALILDVIHWADIPTVWHIVWNATATF 60 ML A IF++T+VLVIWQPKGLGIGWSA GA +AL+ V+H DIP VW+IVWNATA F Sbjct: 8 MLLAGAIFVLTIVLVIWQPKGLGIGWSATLGAVLALVTGVVHPGDIPVVWNIVWNATAAF 67 Query: 61 IAVIIISLLLDKAGFFECAALHVARWGKGNGRRLFVFLVLLGAAVSAIFANDGAALILTP 120 IAVIIISLLLD++GFFE AALHV+RWG G GR LF ++VLLGAAV+A+FANDGAALILTP Sbjct: 68 IAVIIISLLLDESGFFEWAALHVSRWGNGRGRLLFTWIVLLGAAVAALFANDGAALILTP 127 Query: 121 IVIAMLQALRFSPQATLAFVMAAGFIADTASLPLVVSNLVNIVSADYFKLGFAQYAGVMV 180 IVIAML AL FS TLAFVMAAGFIADTASLPL+VSNLVNIVSAD+F LGF +YA VMV Sbjct: 128 IVIAMLLALGFSKGTTLAFVMAAGFIADTASLPLIVSNLVNIVSADFFGLGFREYASVMV 187 Query: 181 PVDLAAVTATLLALAIFFRKDIPKNYDVSQLDAPATAIRDKATFAAGWWVLGLLLLGFLW 240 PVD+AA+ ATL+ L ++FRKDIP+NYD++ L +PA AI+D ATF GW VL LLL+GF Sbjct: 188 PVDIAAIVATLVMLHLYFRKDIPQNYDMALLKSPAEAIKDPATFKTGWVVLLLLLVGFFV 247 Query: 241 LEGLGVPISAVAAAGASILLAVAARGHVIATREVIKGAPWQIVFFSLGMYLVVYGLRNAG 300 LE LG+P+SA+AA GA IL VA RGH I T +V++GAPWQIV FSLGMYLVVYGLRNAG Sbjct: 248 LEPLGIPVSAIAAVGALILFVVAKRGHAINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAG 307 Query: 301 LTNLLTQVLNSLAEHGLWTATLGTGFVTAILSSIMNNMPTVLVGALSIDATTAHGVVRDA 360 LT L+ VLN LA++GLW ATLGTGF+TA LSSIMNNMPTVLVGALSID +TA GV+++A Sbjct: 308 LTEYLSGVLNVLADNGLWAATLGTGFLTAFLSSIMNNMPTVLVGALSIDGSTASGVIKEA 367 Query: 361 MVYANVIGCDLGPKITPIGSLATLLWLHVLDQKKLHISWGYYFRVGAVLTMPVLLVTLAA 420 MVYANVIGCDLGPKITPIGSLATLLWLHVL QK + ISWGYYFR G ++T+PVL VTLAA Sbjct: 368 MVYANVIGCDLGPKITPIGSLATLLWLHVLSQKNMTISWGYYFRTGIIMTLPVLFVTLAA 427 Query: 421 LAIRLQ 426 LA+RL Sbjct: 428 LALRLS 433 >ZarsB [P] COG1055 Na+/H+ antiporter NhaD and related arsenite permeases EcZ Escherichia coli O157:H7 EDL933 Length = 429 Score = 602 bits (1553), Expect = e-172, Method: Compositional matrix adjust. Identities = 316/426 (74%), Positives = 363/426 (85%) Query: 1 MLAAFVIFLITLVLVIWQPKGLGIGWSACGGAAVALILDVIHWADIPTVWHIVWNATATF 60 ML A IF++T+VLVIWQPKGLGIGWSA GA +AL+ V+H DIP VW+IVWNATA F Sbjct: 1 MLLAGAIFVLTIVLVIWQPKGLGIGWSATLGAVLALVTGVVHPGDIPVVWNIVWNATAAF 60 Query: 61 IAVIIISLLLDKAGFFECAALHVARWGKGNGRRLFVFLVLLGAAVSAIFANDGAALILTP 120 IAVIIISLLLD++GFFE AALHV+RWG G GR LF ++VLLGAAV+A+FANDGAALILTP Sbjct: 61 IAVIIISLLLDESGFFEWAALHVSRWGNGRGRLLFTWIVLLGAAVAALFANDGAALILTP 120 Query: 121 IVIAMLQALRFSPQATLAFVMAAGFIADTASLPLVVSNLVNIVSADYFKLGFAQYAGVMV 180 IVIAML AL FS TLAFVMAAGFIADTASLPL+VSNLVNIVSAD+F LGF +YA VMV Sbjct: 121 IVIAMLLALGFSKGTTLAFVMAAGFIADTASLPLIVSNLVNIVSADFFGLGFREYASVMV 180 Query: 181 PVDLAAVTATLLALAIFFRKDIPKNYDVSQLDAPATAIRDKATFAAGWWVLGLLLLGFLW 240 PVD+AA+ ATL+ L ++FRKDIP+NYD++ L +PA AI+D ATF GW VL LLL+GF Sbjct: 181 PVDIAAIVATLVMLHLYFRKDIPQNYDMALLKSPAEAIKDPATFKTGWVVLLLLLVGFFV 240 Query: 241 LEGLGVPISAVAAAGASILLAVAARGHVIATREVIKGAPWQIVFFSLGMYLVVYGLRNAG 300 LE LG+P+SA+AA GA IL VA RGH I T +V++GAPWQIV FSLGMYLVVYGLRNAG Sbjct: 241 LEPLGIPVSAIAAVGALILFVVAKRGHAINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAG 300 Query: 301 LTNLLTQVLNSLAEHGLWTATLGTGFVTAILSSIMNNMPTVLVGALSIDATTAHGVVRDA 360 LT L+ VLN LA++GLW ATLGTGF+TA LSSIMNNMPTVLVGALSID +TA GV+++A Sbjct: 301 LTEYLSGVLNVLADNGLWAATLGTGFLTAFLSSIMNNMPTVLVGALSIDGSTASGVIKEA 360 Query: 361 MVYANVIGCDLGPKITPIGSLATLLWLHVLDQKKLHISWGYYFRVGAVLTMPVLLVTLAA 420 MVYANVIGCDLGPKITPIGSLATLLWLHVL QK + ISWGYYFR G ++T+PVL VTLAA Sbjct: 361 MVYANVIGCDLGPKITPIGSLATLLWLHVLSQKNMTISWGYYFRTGIIMTLPVLFVTLAA 420 Query: 421 LAIRLQ 426 LA+RL Sbjct: 421 LALRLS 426 >ECs4374 [P] COG1055 Na+/H+ antiporter NhaD and related arsenite permeases Ecs Escherichia coli O157:H7 Length = 429 Score = 602 bits (1553), Expect = e-172, Method: Compositional matrix adjust. Identities = 316/426 (74%), Positives = 363/426 (85%) Query: 1 MLAAFVIFLITLVLVIWQPKGLGIGWSACGGAAVALILDVIHWADIPTVWHIVWNATATF 60 ML A IF++T+VLVIWQPKGLGIGWSA GA +AL+ V+H DIP VW+IVWNATA F Sbjct: 1 MLLAGAIFVLTIVLVIWQPKGLGIGWSATLGAVLALVTGVVHPGDIPVVWNIVWNATAAF 60 Query: 61 IAVIIISLLLDKAGFFECAALHVARWGKGNGRRLFVFLVLLGAAVSAIFANDGAALILTP 120 IAVIIISLLLD++GFFE AALHV+RWG G GR LF ++VLLGAAV+A+FANDGAALILTP Sbjct: 61 IAVIIISLLLDESGFFEWAALHVSRWGNGRGRLLFTWIVLLGAAVAALFANDGAALILTP 120 Query: 121 IVIAMLQALRFSPQATLAFVMAAGFIADTASLPLVVSNLVNIVSADYFKLGFAQYAGVMV 180 IVIAML AL FS TLAFVMAAGFIADTASLPL+VSNLVNIVSAD+F LGF +YA VMV Sbjct: 121 IVIAMLLALGFSKGTTLAFVMAAGFIADTASLPLIVSNLVNIVSADFFGLGFREYASVMV 180 Query: 181 PVDLAAVTATLLALAIFFRKDIPKNYDVSQLDAPATAIRDKATFAAGWWVLGLLLLGFLW 240 PVD+AA+ ATL+ L ++FRKDIP+NYD++ L +PA AI+D ATF GW VL LLL+GF Sbjct: 181 PVDIAAIVATLVMLHLYFRKDIPQNYDMALLKSPAEAIKDPATFKTGWVVLLLLLVGFFV 240 Query: 241 LEGLGVPISAVAAAGASILLAVAARGHVIATREVIKGAPWQIVFFSLGMYLVVYGLRNAG 300 LE LG+P+SA+AA GA IL VA RGH I T +V++GAPWQIV FSLGMYLVVYGLRNAG Sbjct: 241 LEPLGIPVSAIAAVGALILFVVAKRGHAINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAG 300 Query: 301 LTNLLTQVLNSLAEHGLWTATLGTGFVTAILSSIMNNMPTVLVGALSIDATTAHGVVRDA 360 LT L+ VLN LA++GLW ATLGTGF+TA LSSIMNNMPTVLVGALSID +TA GV+++A Sbjct: 301 LTEYLSGVLNVLADNGLWAATLGTGFLTAFLSSIMNNMPTVLVGALSIDGSTASGVIKEA 360 Query: 361 MVYANVIGCDLGPKITPIGSLATLLWLHVLDQKKLHISWGYYFRVGAVLTMPVLLVTLAA 420 MVYANVIGCDLGPKITPIGSLATLLWLHVL QK + ISWGYYFR G ++T+PVL VTLAA Sbjct: 361 MVYANVIGCDLGPKITPIGSLATLLWLHVLSQKNMTISWGYYFRTGIIMTLPVLFVTLAA 420 Query: 421 LAIRLQ 426 LA+RL Sbjct: 421 LALRLS 426 >YPO3347 [P] COG1055 Na+/H+ antiporter NhaD and related arsenite permeases Ype Yersinia pestis Length = 429 Score = 580 bits (1496), Expect = e-165, Method: Compositional matrix adjust. Identities = 311/426 (73%), Positives = 360/426 (84%) Query: 1 MLAAFVIFLITLVLVIWQPKGLGIGWSACGGAAVALILDVIHWADIPTVWHIVWNATATF 60 ML A IF++T+VLVIWQPKGLGIGWSA GA +AL+ V+H +DIP VW IVWNATATF Sbjct: 1 MLLAGAIFILTIVLVIWQPKGLGIGWSAMLGAGLALLTGVVHVSDIPVVWQIVWNATATF 60 Query: 61 IAVIIISLLLDKAGFFECAALHVARWGKGNGRRLFVFLVLLGAAVSAIFANDGAALILTP 120 IA+IIISLLLD++GFFE AALHVARWG G+GRRLF +++LLGAAV+A+FANDGAALILTP Sbjct: 61 IAIIIISLLLDESGFFEWAALHVARWGNGHGRRLFTYIILLGAAVAALFANDGAALILTP 120 Query: 121 IVIAMLQALRFSPQATLAFVMAAGFIADTASLPLVVSNLVNIVSADYFKLGFAQYAGVMV 180 IVIAML AL F ATLAFVMAAGFIADTASLPL+VSNLVNIVSAD+F LGF +YA VMV Sbjct: 121 IVIAMLLALGFGRGATLAFVMAAGFIADTASLPLIVSNLVNIVSADFFNLGFTEYAAVMV 180 Query: 181 PVDLAAVTATLLALAIFFRKDIPKNYDVSQLDAPATAIRDKATFAAGWWVLGLLLLGFLW 240 PV+L AV ATL L +FFRKDIP YD+S L AP AIRD TF GW VL LLL+GF Sbjct: 181 PVNLVAVIATLAMLHLFFRKDIPAVYDLSLLKAPQAAIRDMNTFKTGWLVLALLLIGFFA 240 Query: 241 LEGLGVPISAVAAAGASILLAVAARGHVIATREVIKGAPWQIVFFSLGMYLVVYGLRNAG 300 LE LGVP+S VAA GA ILLAVA +GH I T +V++GAPWQIV FSLGMYLVVYGLRNAG Sbjct: 241 LEPLGVPVSLVAAVGALILLAVAKKGHAINTGKVLRGAPWQIVIFSLGMYLVVYGLRNAG 300 Query: 301 LTNLLTQVLNSLAEHGLWTATLGTGFVTAILSSIMNNMPTVLVGALSIDATTAHGVVRDA 360 LT+ ++ +LN L E GLW +TLGTGF+TA LSSIMNN+PTVLVGALSI+ +TA G++++A Sbjct: 301 LTHYISALLNRLGEQGLWASTLGTGFLTAFLSSIMNNLPTVLVGALSIEGSTATGLIKEA 360 Query: 361 MVYANVIGCDLGPKITPIGSLATLLWLHVLDQKKLHISWGYYFRVGAVLTMPVLLVTLAA 420 M+YANVIG DLGPKIT IGSLATLLWLHVL QK + I+WGYYFRVG ++T+PVLLVTL+A Sbjct: 361 MIYANVIGSDLGPKITLIGSLATLLWLHVLSQKNMTITWGYYFRVGIIMTLPVLLVTLSA 420 Query: 421 LAIRLQ 426 LA+RL Sbjct: 421 LALRLS 426 >PA2278 [P] COG1055 Na+/H+ antiporter NhaD and related arsenite permeases Pae Pseudomonas aeruginosa Length = 427 Score = 567 bits (1462), Expect = e-161, Method: Compositional matrix adjust. Identities = 301/413 (72%), Positives = 349/413 (84%) Query: 1 MLAAFVIFLITLVLVIWQPKGLGIGWSACGGAAVALILDVIHWADIPTVWHIVWNATATF 60 ML AF IFL TLVLVIWQP+GLGIGWSA GA +AL L + DIPTVW+IVWNATATF Sbjct: 1 MLIAFAIFLFTLVLVIWQPRGLGIGWSASIGALLALALGSVAPGDIPTVWNIVWNATATF 60 Query: 61 IAVIIISLLLDKAGFFECAALHVARWGKGNGRRLFVFLVLLGAAVSAIFANDGAALILTP 120 IAVI+ISLLLD+AGFFE AALHVARW G+GRRLF F VLLGAAVSA+FANDGAALILTP Sbjct: 61 IAVIVISLLLDEAGFFEWAALHVARWAGGDGRRLFAFCVLLGAAVSALFANDGAALILTP 120 Query: 121 IVIAMLQALRFSPQATLAFVMAAGFIADTASLPLVVSNLVNIVSADYFKLGFAQYAGVMV 180 IV++ML ALRFSP ATLAFVMAAGFIAD+ASLPLVVSNLVNIVSADYF LGF +YA VM+ Sbjct: 121 IVMSMLLALRFSPAATLAFVMAAGFIADSASLPLVVSNLVNIVSADYFGLGFGEYAAVML 180 Query: 181 PVDLAAVTATLLALAIFFRKDIPKNYDVSQLDAPATAIRDKATFAAGWWVLGLLLLGFLW 240 PV+L +V +LL L ++FR+D+P Y + QL P AIRD+ATF G W+L +LL G Sbjct: 181 PVNLVSVATSLLVLFLYFRRDLPPVYALEQLKPPRAAIRDRATFVVGGWMLLVLLAGLFA 240 Query: 241 LEGLGVPISAVAAAGASILLAVAARGHVIATREVIKGAPWQIVFFSLGMYLVVYGLRNAG 300 LE LGVP+SAVAAA A++LLAVA RG VI+TR V++ APWQIV FSLGMYLVVYGL+NAG Sbjct: 241 LEPLGVPVSAVAAACAALLLAVAGRGRVISTRRVLREAPWQIVVFSLGMYLVVYGLKNAG 300 Query: 301 LTNLLTQVLNSLAEHGLWTATLGTGFVTAILSSIMNNMPTVLVGALSIDATTAHGVVRDA 360 LT+LL Q+LN LAEHG+W A LGTG ++A LSS+MNNMP++L+GALSI A+ G VR+A Sbjct: 301 LTDLLAQLLNRLAEHGVWAAALGTGLLSAALSSVMNNMPSMLLGALSIQASDTAGAVREA 360 Query: 361 MVYANVIGCDLGPKITPIGSLATLLWLHVLDQKKLHISWGYYFRVGAVLTMPV 413 M+YANVIGCDLGPKITPIGSLATLLWLHVL +K + I+WGYYFRVGA+LT+PV Sbjct: 361 MIYANVIGCDLGPKITPIGSLATLLWLHVLARKGMRITWGYYFRVGALLTLPV 413