BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0024.0203.p (307 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0405 [T] COG1493 Serine kinase of the HPr protein, regulates ... 330 2e-90 NMB0737 [T] COG1493 Serine kinase of the HPr protein, regulates ... 233 6e-61 NMA0947 [T] COG1493 Serine kinase of the HPr protein, regulates ... 233 6e-61 XF1406 [T] COG1493 Serine kinase of the HPr protein, regulates c... 210 4e-54 BH3590 [T] COG1493 Serine kinase of the HPr protein, regulates c... 160 2e-39 >RSc0405 [T] COG1493 Serine kinase of the HPr protein, regulates carbohydrate metabolism Rso Ralstonia solanacearum Length = 324 Score = 330 bits (846), Expect = 2e-90, Method: Compositional matrix adjust. Identities = 163/274 (59%), Positives = 203/274 (74%), Gaps = 6/274 (2%) Query: 5 SALSIQQLYEENRESLQLGWFAGFPGGERLISGD----AVSASDQVGHLNLIHPGRLQVF 60 + ++ Q ++++N L+L W AG G +R D A SA+D VGHLNLIHP R+QV Sbjct: 4 TGVTAQSIFDDNAADLKLSWVAGLEGADRAFDVDFAKEATSAADLVGHLNLIHPNRIQVL 63 Query: 61 GHQEIEYYNRLSNTSRAYQTAELVAGEPPAFIIAQGLSTPPDILAVCDEKNIPLFSTPLP 120 G EI YY RLS +R Q EL+ EPP ++A G+ PPD+ C + PLF++P+ Sbjct: 64 GKPEITYYQRLSEENRKRQMGELILLEPPFLVVADGVDPPPDLELRCTRSSTPLFTSPIS 123 Query: 121 AAQVIDYLRVYLSKKLAQQITMHGVFMDVLGVGVLITGESGLGKSELGLELISRSHGLVA 180 +A VID+LR+YLS+ A ++TMHGVF+D+LG+GVLI G+SGLGKSELGLELISR HGLVA Sbjct: 124 SAAVIDHLRLYLSRISAPRVTMHGVFLDILGMGVLIMGDSGLGKSELGLELISRGHGLVA 183 Query: 181 DDAVEFARIAPNMIEGRCPPLLANLLEVRGLGLLDIKAIFGETAVRRKMRLKLIVHLVRR 240 DDAV+F R+ P+ IEGRCPPLL NLLEVRGLGLLDIK IFGETAVRRKM++KLIV LVRR Sbjct: 184 DDAVDFVRLGPDFIEGRCPPLLQNLLEVRGLGLLDIKTIFGETAVRRKMKIKLIVQLVRR 243 Query: 241 STLEENYERLPLDAQYEEVLGLPIRKVVIPVPAA 274 + E +ERLPLD+QY +VLGLPI V I V A Sbjct: 244 NDGE--FERLPLDSQYMDVLGLPIHMVKIQVAAG 275 >NMB0737 [T] COG1493 Serine kinase of the HPr protein, regulates carbohydrate metabolism Nme Neisseria meningitidis MC58 Length = 320 Score = 233 bits (593), Expect = 6e-61, Method: Compositional matrix adjust. Identities = 121/268 (45%), Positives = 169/268 (63%), Gaps = 2/268 (0%) Query: 6 ALSIQQLYEENRESLQLGWFAGFPGGERLISGDAVS-ASDQVGHLNLIHPGRLQVFGHQE 64 ++S+++L+++N+ LQL W AG G + I +A VGHLN IHP ++QV G E Sbjct: 3 SISVRRLFDDNQYKLQLAWAAGNSGADNRIGVEADKPVLALVGHLNFIHPNQIQVVGLAE 62 Query: 65 IEYYNRLSNTSRAYQTAELVAGEPPAFIIAQGLSTPPDILAVCDEKNIPLFSTPLPAAQV 124 EY NRL + YQ +L I+A GL P + C + +IPL ++ L + + Sbjct: 63 SEYLNRLESGETGYQFGDLFDISMSLVIVANGLPVSPGLRDYCHKNDIPLLTSKLESPYL 122 Query: 125 IDYLRVYLSKKLAQQITMHGVFMDVLGVGVLITGESGLGKSELGLELISRSHGLVADDAV 184 +D LR+YL + LA HGVF+DV +GVLITG SGLGKSEL LELISR H L+ADDAV Sbjct: 123 MDVLRIYLQRTLAASSVKHGVFLDVFEIGVLITGHSGLGKSELALELISRGHSLIADDAV 182 Query: 185 EFARIAPNMIEGRCPPLLANLLEVRGLGLLDIKAIFGETAVRRKMRLKLIVHLVR-RSTL 243 E RI P +EGRC P+L + LEVRGLG+L+I+ IFGET++R K L+LI++LV Sbjct: 183 ELFRIGPETLEGRCSPMLRDFLEVRGLGILNIRHIFGETSIRPKKILQLIINLVEADDEY 242 Query: 244 EENYERLPLDAQYEEVLGLPIRKVVIPV 271 + +RL + + E +L + +R V +PV Sbjct: 243 MKQLDRLSIRTETESILNVNVRSVTLPV 270 >NMA0947 [T] COG1493 Serine kinase of the HPr protein, regulates carbohydrate metabolism NmA Neisseria meningitidis Z2491 Length = 320 Score = 233 bits (593), Expect = 6e-61, Method: Compositional matrix adjust. Identities = 121/268 (45%), Positives = 169/268 (63%), Gaps = 2/268 (0%) Query: 6 ALSIQQLYEENRESLQLGWFAGFPGGERLISGDAVS-ASDQVGHLNLIHPGRLQVFGHQE 64 ++S+++L+++N+ LQL W AG G + I +A VGHLN IHP ++QV G E Sbjct: 3 SISVRRLFDDNQYKLQLAWAAGNSGADNRIGVEADKPVLALVGHLNFIHPNQIQVVGLAE 62 Query: 65 IEYYNRLSNTSRAYQTAELVAGEPPAFIIAQGLSTPPDILAVCDEKNIPLFSTPLPAAQV 124 EY NRL + YQ +L I+A GL P + C + +IPL ++ L + + Sbjct: 63 SEYLNRLESGETGYQFGDLFDISMSLVIVANGLPVSPGLRDYCHKNDIPLLTSKLESPYL 122 Query: 125 IDYLRVYLSKKLAQQITMHGVFMDVLGVGVLITGESGLGKSELGLELISRSHGLVADDAV 184 +D LR+YL + LA HGVF+DV +GVLITG SGLGKSEL LELISR H L+ADDAV Sbjct: 123 MDVLRIYLQRTLAASSVKHGVFLDVFEIGVLITGHSGLGKSELALELISRGHSLIADDAV 182 Query: 185 EFARIAPNMIEGRCPPLLANLLEVRGLGLLDIKAIFGETAVRRKMRLKLIVHLVR-RSTL 243 E RI P +EGRC P+L + LEVRGLG+L+I+ IFGET++R K L+LI++LV Sbjct: 183 ELFRIGPETLEGRCSPMLRDFLEVRGLGILNIRHIFGETSIRPKKILQLIINLVEADDEY 242 Query: 244 EENYERLPLDAQYEEVLGLPIRKVVIPV 271 + +RL + + E +L + +R V +PV Sbjct: 243 MKQLDRLSIRTETESILNVNVRSVTLPV 270 >XF1406 [T] COG1493 Serine kinase of the HPr protein, regulates carbohydrate metabolism Xfa Xylella fastidiosa 9a5c Length = 316 Score = 210 bits (534), Expect = 4e-54, Method: Compositional matrix adjust. Identities = 107/271 (39%), Positives = 174/271 (64%), Gaps = 4/271 (1%) Query: 5 SALSIQQLYEENRESLQLGWFAGFPGGERLI-SGDAVSASDQV-GHLNLIHPGRLQVFGH 62 ++++ ++L++ R+ L L W AG G R I SGD + + G+LN I+P ++Q+ G Sbjct: 3 TSITARELFDLQRDRLSLRWIAGQQGEHRQIDSGDTRARRPSLAGYLNTIYPNKVQILGT 62 Query: 63 QEIEYYNRLSNTSRAYQTAELVAGEPPAFIIAQGLSTPPDILAVCDEKNIPLFSTPLPAA 122 +E+ + + L R +++ +P +I++ S P D+ D IPL+ +P Sbjct: 63 EELTWLDSLEPNKRKETIEKIIQFQPLTLVISKNQSCPEDMRTAADNSQIPLWVSPKRGH 122 Query: 123 QVIDYLRVYLSKKLAQQITMHGVFMDVLGVGVLITGESGLGKSELGLELISRSHGLVADD 182 +++++L +L++ LA + T+HGVFM++ +GVLITGE+G GKSEL LEL+SR H LVADD Sbjct: 123 ELLNHLSYHLARILAPRATLHGVFMEIYSIGVLITGEAGSGKSELALELLSRGHRLVADD 182 Query: 183 AVEFARIAPNMIEGRCPPLLANLLEVRGLGLLDIKAIFGETAVRRKMRLKLIVHLVRRST 242 A EF +IAP++++G CP +L +LLEVRGLG+L+++ +FG+TA+++ L+LIVHL + T Sbjct: 183 APEFTQIAPDVLDGTCPEILQDLLEVRGLGVLNVRHMFGDTAIKKNKYLRLIVHLTKPIT 242 Query: 243 --LEENYERLPLDAQYEEVLGLPIRKVVIPV 271 YERL D+ VL L + + +PV Sbjct: 243 EPTPSGYERLTGDSGTRHVLDLDVPLITLPV 273 >BH3590 [T] COG1493 Serine kinase of the HPr protein, regulates carbohydrate metabolism Bha Bacillus halodurans Length = 310 Score = 160 bits (406), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 90/256 (35%), Positives = 144/256 (56%), Gaps = 3/256 (1%) Query: 18 ESLQLGWFAGFPGGERLISGDAVS--ASDQVGHLNLIHPGRLQVFGHQEIEYYNRLSNTS 75 E QL +G G R I+ +S + G RLQ+ G E+ +Y +LS Sbjct: 11 ERFQLELLSGEEGIHRSITTSDISRPGIEMAGFFTYYPAKRLQLLGRTELSFYKQLSPVD 70 Query: 76 RAYQTAELVAGEPPAFIIAQGLSTPPDILAVCDEKNIPLFSTPLPAAQVIDYLRVYLSKK 135 + + ++L + P II++GL PP++L ++ +P+ + + ++ L +L + Sbjct: 71 KEERMSKLCTYDTPGIIISRGLEVPPELLKASEKVGVPVLRSNITTTRLSSMLTNFLESQ 130 Query: 136 LAQQITMHGVFMDVLGVGVLITGESGLGKSELGLELISRSHGLVADDAVEFARIAPNMIE 195 LA +HGV +D+ G+GVLITG SG+GKSE L+L+ R H LVADD+VE R + + Sbjct: 131 LAPTTAVHGVLVDIYGIGVLITGSSGVGKSETALDLVRRGHRLVADDSVEIRREHEDTLV 190 Query: 196 GRCPPLLANLLEVRGLGLLDIKAIFGETAVRRKMRLKLIVHLVRRSTLEENYERLPLDAQ 255 GR P L+ +LLE+RGLG++++ +FG AVR R+ L V+L ++ Y+RL L Sbjct: 191 GRSPELIQHLLEIRGLGIINVMTLFGAGAVRPFKRIALCVNLELWDQ-KKVYDRLGLSED 249 Query: 256 YEEVLGLPIRKVVIPV 271 Y ++ + I K+ IPV Sbjct: 250 YLRIMNVDIPKLTIPV 265