BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0024.0186.p (294 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value STM0040 [K] COG0583 Transcriptional regulator Sty Salmonella typ... 189 5e-48 nhaR [K] COG0583 Transcriptional regulator Eco Escherichia coli K12 186 7e-47 ZnhaR [K] COG0583 Transcriptional regulator EcZ Escherichia coli... 184 2e-46 ECs0018 [K] COG0583 Transcriptional regulator Ecs Escherichia co... 184 2e-46 YPO0471 [K] COG0583 Transcriptional regulator Ype Yersinia pestis 174 2e-43 >STM0040 [K] COG0583 Transcriptional regulator Sty Salmonella typhimurium LT2 Length = 299 Score = 189 bits (481), Expect = 5e-48, Method: Compositional matrix adjust. Identities = 106/272 (38%), Positives = 158/272 (58%), Gaps = 4/272 (1%) Query: 1 VARASERLHLTAQTISGQISLFEESLGYKLFKRVGRRLELNDEGRMVFDYAERIFSLGEE 60 V A+E L LT QTI+GQI EE L KLFKR GR LE ++ G +VF YA+++F+L +E Sbjct: 23 VVGAAEALFLTPQTITGQIKALEERLQGKLFKRKGRGLEPSELGELVFRYADKMFTLSQE 82 Query: 61 LEEALRLRPGGRTLQLRVGVADAVPKAIAYLLLESALAMQDPIRIICREGKLDVLLADLA 120 + + + R L VGVADA+ K + +L++A+ + +PI + C E ++LL L+ Sbjct: 83 MLDIVNYRKESNLL-FDVGVADALSKRLVSSVLDAAVVVDEPIHLRCFESTHEMLLEQLS 141 Query: 121 IHKLDIIIADSPMPPNVDVRGYHHLLGECDTSFFATPELARRYRKGFPQSLDAAPFLMPG 180 HKLD+II+D P+ + +GEC SF+ T L K FP L+ L+PG Sbjct: 142 QHKLDMIISDCPIDSTQQEGLFSVKIGECSVSFWCTNPLPE---KAFPACLEERRLLVPG 198 Query: 181 EDAAVRPRLLRWFEKEGIRPQITGEFDDGALLLAFGDAGAGIFAAPTAIAGQIRKQYGLV 240 + + +LL WF +G++ +I GEFDD AL+ AFG IF AP+ + ++ Sbjct: 199 RRSMLGRKLLNWFNSQGLQVEILGEFDDAALMKAFGATHDAIFVAPSLYSLDFYADESVI 258 Query: 241 EIGKTDAIREQFYAISVERRLSHPAVLAIQTA 272 EIG+ + + E+++AI ER + HPAV I A Sbjct: 259 EIGRVENVMEEYHAIFAERMIQHPAVQRICNA 290 >nhaR [K] COG0583 Transcriptional regulator Eco Escherichia coli K12 Length = 301 Score = 186 bits (471), Expect = 7e-47, Method: Compositional matrix adjust. Identities = 107/269 (39%), Positives = 155/269 (57%), Gaps = 10/269 (3%) Query: 1 VARASERLHLTAQTISGQISLFEESLGYKLFKRVGRRLELNDEGRMVFDYAERIFSLGEE 60 V A+E L+LT QTI+GQI EE L KLFKR GR LE ++ G +V+ YA+++F+L +E Sbjct: 23 VVGAAEALYLTPQTITGQIRALEERLQGKLFKRKGRGLEPSELGELVYRYADKMFTLSQE 82 Query: 61 LEEALRLRPGGRTLQLRVGVADAVPKAIAYLLLESALAMQDPIRIICREGKLDVLLADLA 120 + + + R L VGVADA+ K + +L +A+ +PI + C E ++LL L+ Sbjct: 83 MLDIVNYRKESNLL-FDVGVADALSKRLVSSVLNAAVVEGEPIHLRCFESTHEMLLEQLS 141 Query: 121 IHKLDIIIADSPMPPNVDVRGYHHLLGECDTSFFAT---PELARRYRKGFPQSLDAAPFL 177 HKLD+II+D P+ + +GEC SF+ T PE K FP L+ L Sbjct: 142 QHKLDMIISDCPIDSTQQEGLFSVRIGECGVSFWCTNPPPE------KPFPACLEERRLL 195 Query: 178 MPGEDAAVRPRLLRWFEKEGIRPQITGEFDDGALLLAFGDAGAGIFAAPTAIAGQIRKQY 237 +PG + + +LL WF +G+ +I GEFDD AL+ AFG IF APT A Sbjct: 196 IPGRRSMLGRKLLNWFNSQGLNVEILGEFDDAALMKAFGAMHNAIFVAPTLYAYDFYADK 255 Query: 238 GLVEIGKTDAIREQFYAISVERRLSHPAV 266 +VEIG+ + + E+++AI ER + HPAV Sbjct: 256 TVVEIGRVENVMEEYHAIFAERMIQHPAV 284 >ZnhaR [K] COG0583 Transcriptional regulator EcZ Escherichia coli O157:H7 EDL933 Length = 301 Score = 184 bits (467), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 106/269 (39%), Positives = 154/269 (57%), Gaps = 10/269 (3%) Query: 1 VARASERLHLTAQTISGQISLFEESLGYKLFKRVGRRLELNDEGRMVFDYAERIFSLGEE 60 V A+E L+LT QTI+GQI EE L KLFKR GR LE ++ G +V+ YA+++F+L +E Sbjct: 23 VVGAAEALYLTPQTITGQIRALEERLQGKLFKRKGRGLEPSELGELVYRYADKMFTLSQE 82 Query: 61 LEEALRLRPGGRTLQLRVGVADAVPKAIAYLLLESALAMQDPIRIICREGKLDVLLADLA 120 + + + R L VGVAD + K + +L +A+ +PI + C E ++LL L+ Sbjct: 83 MLDIVNYRKESNLL-FDVGVADVLSKRLVSSVLNAAVVEGEPIHLRCFESTHEMLLEQLS 141 Query: 121 IHKLDIIIADSPMPPNVDVRGYHHLLGECDTSFFAT---PELARRYRKGFPQSLDAAPFL 177 HKLD+II+D P+ + +GEC SF+ T PE K FP L+ L Sbjct: 142 QHKLDMIISDCPIDSTQQEGLFSVRIGECGVSFWCTNPPPE------KPFPACLEERRLL 195 Query: 178 MPGEDAAVRPRLLRWFEKEGIRPQITGEFDDGALLLAFGDAGAGIFAAPTAIAGQIRKQY 237 +PG + + +LL WF +G+ +I GEFDD AL+ AFG IF APT A Sbjct: 196 IPGRRSMLGRKLLNWFNSQGLNVEILGEFDDAALMKAFGAMHNAIFVAPTLYAYDFYADK 255 Query: 238 GLVEIGKTDAIREQFYAISVERRLSHPAV 266 +VEIG+ + + E+++AI ER + HPAV Sbjct: 256 TVVEIGRVENVMEEYHAIFAERMIQHPAV 284 >ECs0018 [K] COG0583 Transcriptional regulator Ecs Escherichia coli O157:H7 Length = 301 Score = 184 bits (467), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 106/269 (39%), Positives = 154/269 (57%), Gaps = 10/269 (3%) Query: 1 VARASERLHLTAQTISGQISLFEESLGYKLFKRVGRRLELNDEGRMVFDYAERIFSLGEE 60 V A+E L+LT QTI+GQI EE L KLFKR GR LE ++ G +V+ YA+++F+L +E Sbjct: 23 VVGAAEALYLTPQTITGQIRALEERLQGKLFKRKGRGLEPSELGELVYRYADKMFTLSQE 82 Query: 61 LEEALRLRPGGRTLQLRVGVADAVPKAIAYLLLESALAMQDPIRIICREGKLDVLLADLA 120 + + + R L VGVAD + K + +L +A+ +PI + C E ++LL L+ Sbjct: 83 MLDIVNYRKESNLL-FDVGVADVLSKRLVSSVLNAAVVEGEPIHLRCFESTHEMLLEQLS 141 Query: 121 IHKLDIIIADSPMPPNVDVRGYHHLLGECDTSFFAT---PELARRYRKGFPQSLDAAPFL 177 HKLD+II+D P+ + +GEC SF+ T PE K FP L+ L Sbjct: 142 QHKLDMIISDCPIDSTQQEGLFSVRIGECGVSFWCTNPPPE------KPFPACLEERRLL 195 Query: 178 MPGEDAAVRPRLLRWFEKEGIRPQITGEFDDGALLLAFGDAGAGIFAAPTAIAGQIRKQY 237 +PG + + +LL WF +G+ +I GEFDD AL+ AFG IF APT A Sbjct: 196 IPGRRSMLGRKLLNWFNSQGLNVEILGEFDDAALMKAFGAMHNAIFVAPTLYAYDFYADK 255 Query: 238 GLVEIGKTDAIREQFYAISVERRLSHPAV 266 +VEIG+ + + E+++AI ER + HPAV Sbjct: 256 TVVEIGRVENVMEEYHAIFAERMIQHPAV 284 >YPO0471 [K] COG0583 Transcriptional regulator Ype Yersinia pestis Length = 299 Score = 174 bits (442), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 103/270 (38%), Positives = 152/270 (56%), Gaps = 11/270 (4%) Query: 1 VARASERLHLTAQTISGQISLFEESLGYKLFKRVGRRLELNDEGRMVFDYAERIFSLGEE 60 V A+E L LT QTI+GQI E LG KLFKR GR L ++ G++VF YA+++F L +E Sbjct: 23 VVGAAEALFLTPQTITGQIKALEGRLGGKLFKRRGRGLVPSELGQLVFRYADKMFMLSQE 82 Query: 61 LEEALRLRPGGRTLQLRVGVADAVPKAIAYLLLESALAMQDPIRIICREGKLDVLLADLA 120 + + + R L VGVADA+ K + +LE+A+ + I + C E ++LL L+ Sbjct: 83 MLDIVNYRKESHLL-FDVGVADALSKRLVSQVLETAVVEHEKIHLRCFESTHEMLLEQLS 141 Query: 121 IHKLDIIIADSPMPPNVDVRGYHHLLGECDTSFFA---TPELARRYRKGFPQSLDAAPFL 177 HKLD+I++D P+ + + LGEC SF+ P+L FP SL L Sbjct: 142 QHKLDMILSDCPVDSSQQEGLFSVKLGECSVSFYCRQPVPDLP------FPASLQQKRLL 195 Query: 178 MPGEDAAVRPRLLRWFEKEGIRPQITGEFDDGALLLAFGDAGAGIFAAPTAIAGQIR-KQ 236 +PG + + +LL W +G++ ++ GEFDD AL+ AF IF APT A Sbjct: 196 IPGRRSMLGRKLLNWINSKGLKVEVLGEFDDAALMNAFAVYHDAIFVAPTIYAADTYAND 255 Query: 237 YGLVEIGKTDAIREQFYAISVERRLSHPAV 266 ++EIG+ D ++E++Y I ER + HPAV Sbjct: 256 SEIIEIGRLDNVQEEYYVIFAERMIQHPAV 285