BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0024.0184.p (407 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc0805 [GEPR] COG0477 Permeases of the major facilitator superf... 350 3e-96 YPO1504 [GEPR] COG0477 Permeases of the major facilitator superf... 183 6e-46 SMb21000 [GEPR] COG0477 Permeases of the major facilitator super... 162 1e-39 PA1412 [GEPR] COG0477 Permeases of the major facilitator superfa... 160 4e-39 mlr7399 [GEPR] COG0477 Permeases of the major facilitator superf... 147 4e-35 >RSc0805 [GEPR] COG0477 Permeases of the major facilitator superfamily Rso Ralstonia solanacearum Length = 409 Score = 350 bits (899), Expect = 3e-96, Method: Compositional matrix adjust. Identities = 216/381 (56%), Positives = 264/381 (69%), Gaps = 8/381 (2%) Query: 17 AWKVCLSGMVALSVAMGIGRFAFTPLLPMMLHEGSLSLQMGGWLATANYLGYFAGAMLCA 76 AW+V ++GMVALSVAMGIGRFAFTP+LPMMLH+GS++L G WLAT NYLGYF GA+ C Sbjct: 25 AWRVAIAGMVALSVAMGIGRFAFTPILPMMLHDGSVTLGQGSWLATLNYLGYFVGALACM 84 Query: 77 FHRSKRGVAMLRAGLVVTILLTLGMGVLHQDWIWLWMRFLSGVASAYVFVYTAGWCLQQL 136 R ++R GLV T+LLT GMGVL WL +RF +GV SA VFV+TAGWCL +L Sbjct: 85 ALRGD-AARLIRIGLVATVLLTAGMGVLQGQPAWLVLRFAAGVVSALVFVFTAGWCLHRL 143 Query: 137 TQLGRPELGGVIFCGPGLGIALTGLLSGPMIAAGWLAAGGWILFGVIALGLTALVWKSFS 196 T+LG LGG+IFCGPGLGIA+ GL++ M+A GW A+ WI FGV++ L+A VW + Sbjct: 144 TELGHAALGGIIFCGPGLGIAVPGLVASGMVALGWHASSAWIAFGVLSAVLSAAVWPTVR 203 Query: 197 FDAGRGLNVHPHDSNAAQAPVPESASRKREVMIQVIAYGIAGFGYIITATFLPVIARQAL 256 + PH + +A + +I +AYG+AGFGYI+TATFLPVIAR+ L Sbjct: 204 PER------RPHAAASAPGISGAAPGLGLPTVIITLAYGLAGFGYIVTATFLPVIARRVL 257 Query: 257 P-GSVWPDYFWPIFGLSVAAGAFSATRLSVQGDQRLLLTGAYLMQAAGVLVSILFPTAPG 315 P GS+WPD FWPIFG+ VA GA +TR+S+ D R LL AY MQA V SI++PT G Sbjct: 258 PAGSIWPDLFWPIFGVGVALGALLSTRISLARDNRTLLAAAYAMQAVAVAASIVWPTVGG 317 Query: 316 FALSCLLLGLPFTAITLFGMREARRLRREQASSLMALMTAAYGIGQIAGPPLATALVHGS 375 ALS LLLGLPFTAITLF MREARRL LM LMTA YGIGQIAGPPLA L + Sbjct: 318 LALSSLLLGLPFTAITLFAMREARRLWPHAVPRLMGLMTAVYGIGQIAGPPLANRLFAAT 377 Query: 376 GSFTPSLCVAAVTLLIGAGLY 396 G F SL AA +L++G ++ Sbjct: 378 GGFDASLAAAAASLVLGMAMF 398 >YPO1504 [GEPR] COG0477 Permeases of the major facilitator superfamily Ype Yersinia pestis Length = 383 Score = 183 bits (465), Expect = 6e-46, Method: Compositional matrix adjust. Identities = 142/390 (36%), Positives = 198/390 (50%), Gaps = 25/390 (6%) Query: 16 LAWKVCLSGMVALSVAMGIGRFAFTPLLPMMLHEGSLSLQMGGWLATANYLGYFAG---A 72 +A +V LSG +AL VAMGIGRFAFTP +P+M+ E +L G +A NYLGY G A Sbjct: 1 MALRVALSGFLALVVAMGIGRFAFTPQVPLMIAEHQFTLTSAGLVAAFNYLGYLFGAFDA 60 Query: 73 MLCAFHRSKRGVAMLRAGLVVTILLTLGMGVLHQDWIWLWMRFLSGVASAYVFVYTAGWC 132 M + H +R L GL LLTL V+ W +RF G AS + V A W Sbjct: 61 MRASRHVERR----LWLGLWGAALLTLLSAVVVGPWWHGLVRFAIGWASGWSMVLIAAWT 116 Query: 133 LQQLTQLGRPELGGVIFCGPGLGIALTGLLSGPMIAAGWLAAGGWILFGVIALGLTALVW 192 ++L GRP L +F GPG GI ++G+L+ + + AA W ++GV+AL + A Sbjct: 117 NERLAHFGRPALSAAVFAGPGAGIFISGMLAVAIHSYDLSAAEAWWVYGVLALVIIA--- 173 Query: 193 KSFSFDAGRGLNVHPHDSNAAQAPVPESASRKREVMIQVIAYGIAGFGYIITATFLPVIA 252 S S + RG + H P+ + + KR V +Y +AGFGYI+ ATFL +A Sbjct: 174 -SISINLPRGGEL--HRPQVVAVPLTLTPALKRLVW----SYSLAGFGYILPATFLSQMA 226 Query: 253 RQALPGSVWPDYFWPIFG----LSVAAGAFSATRLSVQGDQRLLLTGAYLMQAAGVLVSI 308 P S++ + WP+FG + +A G TR + RL LT +QA GVL + Sbjct: 227 SARFPDSLFAQFVWPVFGGAAVIGIALGIL--TRHCLTSQTRLALT--LWVQALGVLCAE 282 Query: 309 LFPTAPGFALSCLLLGLPFTAITLFGMREARRLRREQASSLMALMTAAYGIGQIAGPPLA 368 P G AL LL G F ++ ++ R L E + L+T Y IGQ+ GP L+ Sbjct: 283 WVPGVSGLALGALLTGGGFLSVVQLSLQHGRELAPEHTRYMAGLLTTGYAIGQLVGPILS 342 Query: 369 TALVHGSGSFTPSLCVAAVTLLIGAGLYYR 398 + P+L VA V L+I GL + Sbjct: 343 AISTTLTHRLEPALYVAVVALIIAGGLVIK 372 >SMb21000 [GEPR] COG0477 Permeases of the major facilitator superfamily Sme Sinorhizobium meliloti Length = 377 Score = 162 bits (410), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 133/377 (35%), Positives = 197/377 (52%), Gaps = 31/377 (8%) Query: 28 LSVAMGIGRFAFTPLLPMMLHEGSLSLQMGGWLATANYLGYFAGAMLCAF---HRSKRGV 84 ++VAMG GRF++TP+LP M+ + LS G +A+AN++GY AGA+L + H +RGV Sbjct: 1 MAVAMGFGRFSYTPILPAMMTDTGLSPADAGLVASANFIGYLAGAVLAGYRWAHGRERGV 60 Query: 85 AMLRAGLVVTILLTLGMGVLHQDWIWLWMRFLSGVASAYVFVYTAGWCLQQLTQLGRPEL 144 + A LV T LL MG+ + +RFL+G+ASA+ ++ +G L Q + Sbjct: 61 GL--AALVATTLLLAAMGLTSSVLAYSIIRFLAGLASAFAMIFISGIVLGQGLAARSEHV 118 Query: 145 GGVIFCGPGLGIALTGL------LSGPMIAAGWLAAGGWILFGVIALGLTALVWKSFSFD 198 V F G G GIAL+ + L+G +A ++ W + ++AL T LV Sbjct: 119 PSVHFGGVGFGIALSSIAVWVAPLAG--VAGLSMSQADWFVGALVALAGTVLVAAL---- 172 Query: 199 AGRGLNVHPHDSNAAQAPVPESASRKREVMIQVIAYGIAGFGYIITATFLPVIARQALPG 258 L H +N + VP R R +M + YG GFGY+ITATFL +AR A G Sbjct: 173 ----LPASRHAANGGRPEVPLV--RSRPLMAMTLTYGFFGFGYVITATFLVAMARDASGG 226 Query: 259 SVWPDYFWPIFGLSVAAGAFSATRLSVQGDQRLLLTGAY----LMQAAGVLVSILFPTAP 314 W I G+S A + R +V R L G Y L++A G+++++ P+ Sbjct: 227 HSVEFLAWLITGVSAALSVY-LWRFAVP---RFGLAGVYAIGLLVEAVGLVLTVSLPSPY 282 Query: 315 GFALSCLLLGLPFTAITLFGMREARRLRREQASSLMALMTAAYGIGQIAGPPLATALVHG 374 + L+LG F +T +G++ R+L E +A MTAA+GIGQI GP +A L Sbjct: 283 APLVGGLMLGATFMMVTAYGLQIGRQLAPESPRRALAFMTAAFGIGQIVGPLVAGWLAER 342 Query: 375 SGSFTPSLCVAAVTLLI 391 +GS+ VAAV L+I Sbjct: 343 TGSYALPTLVAAVVLMI 359 >PA1412 [GEPR] COG0477 Permeases of the major facilitator superfamily Pae Pseudomonas aeruginosa Length = 397 Score = 160 bits (406), Expect = 4e-39, Method: Compositional matrix adjust. Identities = 138/370 (37%), Positives = 180/370 (48%), Gaps = 16/370 (4%) Query: 32 MGIGRFAFTPLLPMMLHEGSLSLQMGGWLATANYLGYFAGAMLCAFHRSKRGVAM-LRAG 90 MG+GRF+ TP LP ++ EG L L G LA ANYLGY GA+ F R R + L G Sbjct: 24 MGVGRFSLTPQLPHLIREGQLDLTGAGLLAAANYLGYLVGALDALFAREARQARLRLLVG 83 Query: 91 LVVTILLTLGMGVLHQDWIWLWMRFLSGVASAYVFVYTAGWCLQQLTQLGRPELGGVIFC 150 L LTL W +RF GVASA+V + + + GR LG ++F Sbjct: 84 LWACFGLTLASVWAEGFWPHALLRFGLGVASAWVLIMVTALSQRLAAESGRARLGALVFA 143 Query: 151 GPGLGIALTGLLSGPMIAAGWLAAGGWILFGVIALGLTALVWKSFSFDAGRGLNVHPHDS 210 GPG+G+ +TGLL+ A G + W LF +AL L ++ A RG HD+ Sbjct: 144 GPGIGVMVTGLLAALGNALGQDSVFIWKLFADLALVLILMLLPLLPRPAARGAG---HDA 200 Query: 211 NAAQAPVPESASRKREVMIQVIAYGIAGFGYIITATFLPVIARQALPGSVWPDYFWPIFG 270 P +AS + AYG+ G GYII ATFL +A G D FWP FG Sbjct: 201 -------PATASENAGLGRLTWAYGLVGLGYIIPATFLSQMAAARFHGQWQADLFWPCFG 253 Query: 271 LSVAAGA--FSATRLSVQGDQRLLLTGAYLMQAAGVLVSILFPTAPGFALSCLLLGLPFT 328 L+ A G S R G +R L+ GA +QA GVL +L P G AL +L GLPF Sbjct: 254 LASATGVVLISLRRQRPDGTRRWLV-GALWLQALGVLACLL-PGIGGLALGVVLTGLPFL 311 Query: 329 AITLFGMREARRLRREQASSLMALMTAAYGIGQIAGPPLATALVHGSGSFTPSLCVAAVT 388 A M+ AR L +T + +GQ+ GP LA H +G P+L +A + Sbjct: 312 AGMQLVMQYARELAPHTPQRNAGQLTTGFALGQLLGPLLAALSTHFAGGLQPALALAGLG 371 Query: 389 LLIGAGLYYR 398 L+ AGL R Sbjct: 372 LVF-AGLLLR 380 >mlr7399 [GEPR] COG0477 Permeases of the major facilitator superfamily Mlo Mesorhizobium loti Length = 401 Score = 147 bits (371), Expect = 4e-35, Method: Compositional matrix adjust. Identities = 138/397 (34%), Positives = 200/397 (50%), Gaps = 33/397 (8%) Query: 6 ASHPSASLHALAWKVCLSGMVALSVAMGIGRFAFTPLLPMMLHEGSLSLQMGGWLATANY 65 A+ SA+ AL + V +GM+A++VAMGIGRF +TP+LP M+ E LS GW+A+ANY Sbjct: 14 AAMRSATSTALRFSV--AGMIAMAVAMGIGRFVYTPILPGMMEELHLSPANAGWIASANY 71 Query: 66 LGYF-AGAMLCAFHRSKRGVAMLRAGLVVTILLTLGMGVLHQDWIWLWMRFLSGVASAYV 124 LGY R ++ GL + +L MG+ +L +RFL+G+ASA+V Sbjct: 72 LGYLVGAFAAAGGWAHGRERLLMLGGLGASTILAALMGLTDAMAAFLLIRFLAGLASAFV 131 Query: 125 FVYTAGWCLQQLTQLGRPELGGVIFCGPGLGIALTGLLSGPMI------AAGWLAAGGWI 178 V+ A + GR +L F G GLGIA++ ++ ++ AAGWL + Sbjct: 132 MVFMASIVFSHINAAGRGDLQAWHFGGVGLGIAISAVMMAVLVTEHAGWAAGWLWSAAIS 191 Query: 179 LFGVIALGLTALVWKSFSFDAGRGLNVHPHDSNAAQAPVPESASRKREVMIQVIAYGIAG 238 G + + L A N P + QA + + R + +IAYG+ G Sbjct: 192 ACGFVVVALLA--------------NEGPLANG--QAVREPALPKDRSLTKIIIAYGLFG 235 Query: 239 FGYIITATFLPVIARQALPGSVWPDYFWPIFGLSVAAGAFSATRLSVQGDQRLLLTGAY- 297 FGY++TATFL I RQ V+ W + GL+ F +T L + R+ L AY Sbjct: 236 FGYVVTATFLVAIVRQGGGSRVFEAMVWLVAGLA----GFPSTWLWQKIAGRVGLNAAYA 291 Query: 298 ---LMQAAGVLVSILFPTAPGFALSCLLLGLPFTAITLFGMREARRLRREQASSLMALMT 354 L++ GV S+ G L LLLG F AIT G++ AR+ + + ALMT Sbjct: 292 LACLIEVIGVTASVALGGYSGPLLGGLLLGGTFIAITALGLQAARQQAPQAPRRIFALMT 351 Query: 355 AAYGIGQIAGPPLATALVHGSGSFTPSLCVAAVTLLI 391 A++G+GQI GP A L SG F + VAA L++ Sbjct: 352 ASFGLGQIIGPIAAGLLAQMSGDFFLASIVAAAMLVV 388