BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0024.0153.p (485 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value BMEII0126 [E] COG0531 Amino acid transporters Bme Brucella melit... 387 e-107 mll6718 [E] COG0531 Amino acid transporters Mlo Mesorhizobium loti 197 6e-50 CAC0852 [E] COG0531 Amino acid transporters Cac Clostridium acet... 117 7e-26 TVN0718 [E] COG0531 Amino acid transporters Tvo Thermoplasma vol... 110 6e-24 TVN0939 [E] COG0531 Amino acid transporters Tvo Thermoplasma vol... 92 3e-18 >BMEII0126 [E] COG0531 Amino acid transporters Bme Brucella melitensis Length = 497 Score = 387 bits (993), Expect = e-107, Method: Compositional matrix adjust. Identities = 214/438 (48%), Positives = 309/438 (70%), Gaps = 1/438 (0%) Query: 11 KEENALRKNALGVGFIIFFVVSAASPLSVIAGGFPIGIMLGNGPGTPALLVLILLLLLAF 70 ++ N LRKN+LGV + F VVSAA+PL+ +A P+ ++LGNGPG P +++ +LL F Sbjct: 23 EQTNQLRKNSLGVAAVTFLVVSAAAPLTSVAAAVPLSMLLGNGPGIPLTFLIVTGVLLMF 82 Query: 71 SVGYTTMARHVTNAGGFYAFSSAGLGGMAGGVAGVLAMFAYNILQIGLYGMFGGVMSATI 130 SVGY MARH+ NAG FYAF++ GLGG+ GG A +LA+ AYN +QIG++G+FG S + Sbjct: 83 SVGYVAMARHIRNAGAFYAFTAQGLGGLMGGAAALLAILAYNAMQIGVFGLFGAATSGFM 142 Query: 131 FDIFGVQLAWWVYAALAMLSVAVLGYRNIDLSARLLSVVVVAEYLAVLVLDFCILRAGGD 190 + G+ L WW + + + +VAVLGYR +DLSAR+L+V+VV EYL VLV+D IL +GGD Sbjct: 143 ASL-GLDLPWWAWTYIGIAAVAVLGYRRVDLSARVLTVLVVLEYLVVLVIDAAILFSGGD 201 Query: 191 HGVNLDSFAPANVMSGTPSIGLLFAFAAFIGFEATTIYGEEAKNPKRAIPIATYTSVLLI 250 G+ ++ F P+ +SGTP+IG+LF FAAFIGFEATT+Y EEA++P R +P ATY SVL+I Sbjct: 202 SGLTMEPFTPSAFLSGTPAIGVLFCFAAFIGFEATTVYSEEARDPGRTVPRATYISVLII 261 Query: 251 GAFYGISLWALIIGAGSDKVVKLLEHMQDPTAFIYVMSDHYAGGGLTAVIRILFVISIYA 310 G FY ++ W ++ GAG+ K+V L+ +QDPT F++ +++ Y G + V+ +LFV S++A Sbjct: 262 GIFYMLTAWLMVNGAGAGKLVGELQALQDPTTFLFGLAERYVGHWIIPVMNLLFVTSLFA 321 Query: 311 GLLAFHSSAARYFYAVGRDGLLHRLLGTTHKTYQSPHMGSALQSAIAAVVVTLFAVSGAH 370 G++AFH+ ARY Y GR+GLL R LG TH YQSPH+GS +Q+AIA VV +FAV+G Sbjct: 322 GVVAFHNGVARYMYVAGREGLLPRGLGVTHPQYQSPHVGSIVQTAIAITVVGIFAVTGQD 381 Query: 371 PILHLFAWFSSLAALCLMLLMIMTSAAVICYFRRHPQACDSAWRVRILPAVSLVALLYIL 430 P+L LF+W +++ L +MLLM T+ A+I +F R P + + R+LP V+ L ++ Sbjct: 382 PVLALFSWATNVGTLAIMLLMTFTAFAIIAFFARRPGLESNPFTTRVLPLVTGTILGLLV 441 Query: 431 CTAILHFDVLTGASKSMS 448 ++F L GA+ M+ Sbjct: 442 IYIAVNFGSLAGANGFMA 459 >mll6718 [E] COG0531 Amino acid transporters Mlo Mesorhizobium loti Length = 508 Score = 197 bits (500), Expect = 6e-50, Method: Compositional matrix adjust. Identities = 149/504 (29%), Positives = 254/504 (50%), Gaps = 37/504 (7%) Query: 4 LDCSKHDKEENALRKNALGVGFIIFFVVSAASPLSVIAGGFPIGIMLGNGPGTPALLVLI 63 +D SK + N L A+G+ ++F V+ A+P+S + G P G G TPA ++ Sbjct: 10 IDVSKSN-SINLLHSKAVGLAGVLFLAVTGAAPMSAMLGNVPFAAGYGIGKYTPAAFLMA 68 Query: 64 LLLLLAFSVGYTTMARHVTNAGGFYAFSSAGLGGMAGGVAGVLAMFAYNILQIGLYGMFG 123 ++L FS+GY MA V++ GGFY+F S GLG G AG+ ++ Y++ + L G+F Sbjct: 69 TIVLTIFSIGYAAMASRVSSVGGFYSFISQGLGREVGMSAGIGSLACYSLFEASLTGLFA 128 Query: 124 GVMSATIFDIFGVQLAWWVYAALAMLSVAVLGYRNIDLSARLLSVVVVAEYLAVLVLDFC 183 + + FG+ + W V A ++ +A L YR++ +SARLL + ++ E + +++ Sbjct: 129 FFGNLWLSQHFGINVPWIVLALAMIVVIAALAYRDVKVSARLLGIALILEVIMLVIFSLG 188 Query: 184 ILRAGGDHGVNLDS------FAP--------ANVMSGTPSIGLLFAFAAFIGFEATTIYG 229 ++ A G + DS F P + +G ++G+ AF +++GFE Y Sbjct: 189 VIFAHGGTNFSGDSLNVFKVFTPVAEQKVGDVAIPAGEAAVGIFMAFWSWVGFEMAPNYA 248 Query: 230 EEAKNPKRAIPIATYTSVLLIGAFYGISLWALIIG--AGSDKVVKLLEHMQDPTAFIYVM 287 EE+++PKR IP + SV+ +G FY W + +D V K D F Sbjct: 249 EESRDPKRIIPQSLLISVIGLGLFYTFVSWCAVAAYPTEADMVAKAFS---DGVNFFLTP 305 Query: 288 SDHYAGGGLTAVIRILFVISIYAGLLAFHSSAARYFYAVGRDGLLHRLLGTTHKTYQSPH 347 + GG ++ +L + S +A +AFH++A+RY Y++ R+G+L + + TH ++SPH Sbjct: 306 VQSFVGGWGYQLMSLLILTSSFACGMAFHNTASRYLYSLAREGVLPQAIAETHDHHKSPH 365 Query: 348 MGSALQSAIAAVVVTLFAVS------GAHPILHLFAWFSSLAALCLMLLMIMTSAAVICY 401 SALQS +AAV V L+ ++ L ++ F+ L L++L + S A+ + Sbjct: 366 KASALQSVLAAVWVLLYGLAYGFDDPSGQAWLGVYTLFAVLGTGLLLVLQAVVSLAIYMW 425 Query: 402 FRRHPQACDSAWRVRILPAVSLVALLYILCTAILHFDVLTGASKSMSWALCSMIP---LA 458 F+++ S I P +SLV L ++ T + + L G + IP LA Sbjct: 426 FKKN--GGGSMLTTVIAPLISLVVQLVLVYTLVANLATLGGTN-----GFARSIPYVGLA 478 Query: 459 ILI-GVMLASRLRRCAPMRFAALG 481 ILI G++ L+ P + +G Sbjct: 479 ILIVGLIWGFVLKSANPKAYENIG 502 >CAC0852 [E] COG0531 Amino acid transporters Cac Clostridium acetobutylicum Length = 462 Score = 117 bits (293), Expect = 7e-26, Method: Compositional matrix adjust. Identities = 93/355 (26%), Positives = 174/355 (49%), Gaps = 14/355 (3%) Query: 79 RHVTNAGGFYAFSSAGLGGMAGGVAGVLAMFAYNILQIGLYGMFGGVMSATIFDIFGVQL 138 + +++G Y F+ LG G + G + AY +L G G S + FG+Q+ Sbjct: 68 HYFSSSGSLYTFTEKTLGEKFGFLTGWALLLAYVMLAAGCCAELGAFFSK-FLNYFGIQI 126 Query: 139 AWWVYAALAMLSVAVLGYRNIDLSARLLSVVVVAEYLAVLVLDFCIL-RAGGDHGVNLDS 197 AW + L + +LG + +S R++ + L + +L IL + G G++ Sbjct: 127 AWLPLSMFFSLGIVILGIIDAKISTRIMLAMEGISILLIFILSIVILFKVGSTKGLSPIP 186 Query: 198 FAP-ANVMSGTPSIGLLFAFAAFIGFEATTIYGEEAKNPKRAIPIATYTSVLLIGAFYGI 256 F N S S +L AF +FIGFE+ + GEE KNPK+ IP+A ++V + G FY + Sbjct: 187 FKTNKNSFSTLASTSVL-AFLSFIGFESASSLGEETKNPKKFIPLAIGSAVFVTGIFYLL 245 Query: 257 SLWALIIGAGSDKVVKLLEHMQDPTAFIYVMSDHYAGGGLTAVIRILFVISIYAGLLAFH 316 S ++ +IG G D K L+ + + + +S Y + +S ++ L Sbjct: 246 SSYSQVIGFGVD--AKGLKALSTSSLPLTDLSTKYISRTFGIFLLFSASLSCFSCSLGSA 303 Query: 317 SSAARYFYAVGRDGLLHRLLGTTHKTYQSPHMGSALQSAIAAVV-VTLFAVSGAHPILHL 375 + +R +A+ +DG++ + L HK + +P++G L + +A + + LF G + Sbjct: 304 CAGSRILFAMSKDGIISKKLSIIHKKHCTPYIGIILITIVAMFLQLILFKKDG----IEA 359 Query: 376 FAWFSSLAALCLMLLMIMTSAAVICYFRRHPQACDSAWRVRILPAVSLVALLYIL 430 F + +++ +L +++ + TS + +F+R + + +P +S+ ALLY+L Sbjct: 360 FNYLATIGSLAIIVSYLFTSIGAVVFFKRTKEIKNLNI---FIPILSIAALLYVL 411 >TVN0718 [E] COG0531 Amino acid transporters Tvo Thermoplasma volcanium Length = 476 Score = 110 bits (276), Expect = 6e-24, Method: Compositional matrix adjust. Identities = 119/436 (27%), Positives = 202/436 (46%), Gaps = 29/436 (6%) Query: 9 HDKEENALRKNALGVGFIIFFVVSAASPLSVIAGGF--PIGIMLGNGPGTPALLVLILLL 66 +D L+ NA+G ++ ++ SPL +A I LG+ P A L+ I + Sbjct: 2 NDTSAGHLKSNAVGFWPLLGQAIAMISPLGAVAATMTGSASIALGSLPL--AYLIAIFAV 59 Query: 67 LLAFSVGYTTMARHVTNAGGFYAFSSAGLGGMAGGVAGVLAMFAYNILQIGLYGMFGGVM 126 L + Y ++ + +AGGFY ++ G G G ++G + F+Y + V Sbjct: 60 LFWINTPYQ-YSKKIASAGGFYTYNRNGAGQYYGSISGYVLFFSYYMTYTNAILFITAVF 118 Query: 127 SATIFDIF-GVQLAWWVYAALAM---LSVAVLGYRNIDLSAR--LLSVVVVAEYLAVLVL 180 +F+IF G+ L W++ + + L V + Y I+ S + L S ++ L +L L Sbjct: 119 IPGLFEIFFGITLTAWIWIPVLIAIGLLVLLPAYLGIEGSTKYSLASSIIQIALLVILSL 178 Query: 181 DFCILRAGGDHGVNLDSFAPANVMSGTPS-IGLLFAFAAFIGFEATTIYGEEAKNPKRAI 239 +++ + L+ F P P +G++ A + G A GEEAK PKR I Sbjct: 179 TIIVIKGPAN---TLEPFTPKPAGGFGPVFVGMILAIFSMSGSSAVVSLGEEAKQPKRNI 235 Query: 240 PIATYTSVLLIGAFYGISLWALIIGAGSDKVVKLLEHMQDPTAFIYVMSD--------HY 291 A S L+ G + ++ +AL IG G + + +P A + V Y Sbjct: 236 RNALLISFLVTGVVFVLTSYALTIGWGISNMNTFAQ--SNPAAGLTVGQGVPGIIEALKY 293 Query: 292 AGGGLTAVIRILFVISIYAGLLAFHSSAARYFYAVGRDGLLHRLLGTTHKTYQSPHMGSA 351 G + + I V S+Y G LA +SAAR F+A+ RDG+ ++ TH Y++PH+ Sbjct: 294 MGMPMAIAMMIFAVNSLYTGSLAPLNSAARMFFAMSRDGIAPKVFAKTHGKYKTPHVALV 353 Query: 352 LQSAIAAVVVTLFAVSGAHPILHLFAWFSSLAALCLMLLMIMTSAAVICYFRRHPQACDS 411 A ++V+L A P + F + + +A+ L + IMT ++ F++ + S Sbjct: 354 FI-AFTGILVSLIAGLAMGP-FNGFLYLVTASAVALFIGHIMTDISLPVAFKKFRE--FS 409 Query: 412 AWRVRILPAVSLVALL 427 + +LPA+SLV LL Sbjct: 410 VLKHAVLPAISLVLLL 425 >TVN0939 [E] COG0531 Amino acid transporters Tvo Thermoplasma volcanium Length = 487 Score = 92.0 bits (227), Expect = 3e-18, Method: Compositional matrix adjust. Identities = 105/431 (24%), Positives = 200/431 (46%), Gaps = 37/431 (8%) Query: 57 PALLVLILLLLLAFSVGYTTMARHVTNAGGFYAFSSAGLGGMAGGVAGVLAMFAYNILQI 116 P +L+L L++ S +R +++AGG+Y F S GLG AG V L+ Y IL Sbjct: 51 PLILLLSLVVYALMSYSMYEFSRKLSSAGGYYTFVSRGLGNSAGFVTA-LSYITYEILSF 109 Query: 117 GLYGMFGGV-MSATIFDIFGV-----QLAWWVYAALAMLSVAVLGYRNIDLSARLLSVVV 170 +G+ G + + IF G+ + W A + + V++L Y I S R +S V Sbjct: 110 TGFGILGFLGFAYAIFPSLGIAIPDPEFLWMPVAFVFIGLVSLLIYLGIKPSLRFVSYTV 169 Query: 171 VAEYLAVLVLDFCILRAGGDHGVNLDSFAPANVMSGTPSI--GLLFAFAAFIGFEATTIY 228 E +A L+ L VNL+ F P + + +I +++A AF+G + Sbjct: 170 FIE-VAFLIFTSVALIVMHHTSVNLEPFTPTPMGNDPYAIFAMMIYAIGAFVGIGGSIPI 228 Query: 229 GEEAKNPKRAIPIATYTSVLLIGAFYGISLWALIIGAGSDKVVKLLEHMQDPTAFIYVMS 288 EE K PKR +P+A ++ ++G ++ +A ++ G ++ + L DP + + Sbjct: 229 AEETKKPKRNVPLAILVTIAVLGITIILASYAQVVSWGLNR-IDLFGSSSDPYPLLTIY- 286 Query: 289 DHYAGGGLTAVIRILFVI----SIYAGLLAFHSSAARYFYAVGRDGLLHRLLGTTHKTYQ 344 H A G L+ ++ +I S + ++ ++A R +++ R+G L L ++ Sbjct: 287 -HSAFGPLSIILFWAIIIIVLNSFFTATVSLGTNATRVIFSMAREGALPSFLSEMNRNNG 345 Query: 345 SPHMGSALQSAIAAVVVTLFAVSGAHPILHLFAWFSSLAAL---CLMLLM---------- 391 +P M + +AI+ +V G F FS + AL + LL+ Sbjct: 346 TPTMAMIVLTAISIAIVI-----GVGAGFEFFGHFSPVNALLTSSVFLLILESPITYIVH 400 Query: 392 IMTSAAVICYFRRHPQ-ACDSAWRVRILPAVSLVALLYILCTAILHFDVLTGASKSMSWA 450 I+T+ ++ Y ++ + ++ ++P+VS V L+ + I +F++ + S+A Sbjct: 401 ILTNTSLYSYMKKRTKMKAKDLFKYLVIPSVSTVTLIAAIVAGI-YFNLFLVDAIYASFA 459 Query: 451 LCSMIPLAILI 461 L ++I ++ L+ Sbjct: 460 LIAIIIISTLV 470