BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0024.0021.p (198 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2950 [E] COG0131 Imidazoleglycerol-phosphate dehydratase Rso ... 337 8e-93 PA5143 [E] COG0131 Imidazoleglycerol-phosphate dehydratase Pae P... 326 2e-89 NMB1583 [E] COG0131 Imidazoleglycerol-phosphate dehydratase Nme ... 313 2e-85 NMA1772 [E] COG0131 Imidazoleglycerol-phosphate dehydratase NmA ... 313 2e-85 all4390 [E] COG0131 Imidazoleglycerol-phosphate dehydratase Nos ... 245 4e-65 >RSc2950 [E] COG0131 Imidazoleglycerol-phosphate dehydratase Rso Ralstonia solanacearum Length = 196 Score = 337 bits (865), Expect = 8e-93, Method: Compositional matrix adjust. Identities = 162/194 (83%), Positives = 179/194 (92%) Query: 5 RTAEVVRNTNETQIRVAINLDGTGQQKLDTGVPFLDHMLDQIARHGLIDLDIHAKGDLHI 64 R AEV RNT+ETQIRVA++LDGTG+Q L+TGVPFLDHMLDQIARHG++DLD+ A GD HI Sbjct: 3 RRAEVTRNTSETQIRVALDLDGTGKQTLNTGVPFLDHMLDQIARHGMVDLDVTATGDTHI 62 Query: 65 DAHHTVEDVGITLGMAFAKAIGDKKGIRRYGHAYVPLDEALSRVVIDFSGRPGLEYHIPF 124 D HHTVEDVGITLG A AKAIGDKKGI RYGH+YVPLDEALSRVVIDFSGRPGLE+H+PF Sbjct: 63 DDHHTVEDVGITLGQAVAKAIGDKKGIVRYGHSYVPLDEALSRVVIDFSGRPGLEFHVPF 122 Query: 125 TRSMIGSFDVDLTSEFFHGFVNHAQVTLHVDNLRGVNAHHQAETVFKAFGRALRMAVELD 184 TR+ +GSFDVDL+ EFF GFVNHA VTLH+DNLRGVNAHHQ ETVFKAFGRALRMAVE+D Sbjct: 123 TRARVGSFDVDLSIEFFRGFVNHAGVTLHIDNLRGVNAHHQIETVFKAFGRALRMAVEID 182 Query: 185 PRAAGTIPSTKGSL 198 PRAAGTIPSTKG+L Sbjct: 183 PRAAGTIPSTKGAL 196 >PA5143 [E] COG0131 Imidazoleglycerol-phosphate dehydratase Pae Pseudomonas aeruginosa Length = 197 Score = 326 bits (836), Expect = 2e-89, Method: Compositional matrix adjust. Identities = 156/194 (80%), Positives = 171/194 (88%) Query: 5 RTAEVVRNTNETQIRVAINLDGTGQQKLDTGVPFLDHMLDQIARHGLIDLDIHAKGDLHI 64 R A V R+T ETQI+V+I+LDGTG+ + DTGVPFLDHM+DQIARHGLIDLDI KGDLHI Sbjct: 4 RKASVARDTLETQIKVSIDLDGTGKARFDTGVPFLDHMMDQIARHGLIDLDIECKGDLHI 63 Query: 65 DAHHTVEDVGITLGMAFAKAIGDKKGIRRYGHAYVPLDEALSRVVIDFSGRPGLEYHIPF 124 D HHTVED+GITLG AFAKAIGDKKGIRRYGHAYVPLDEALSRVVIDFSGRPGL+ H+PF Sbjct: 64 DDHHTVEDIGITLGQAFAKAIGDKKGIRRYGHAYVPLDEALSRVVIDFSGRPGLQMHVPF 123 Query: 125 TRSMIGSFDVDLTSEFFHGFVNHAQVTLHVDNLRGVNAHHQAETVFKAFGRALRMAVELD 184 TR+ +G FDVDL EFF GFVNHAQVTLH+DNLRG N HHQ ETVFKAFGRALRMA+ELD Sbjct: 124 TRASVGGFDVDLFMEFFQGFVNHAQVTLHIDNLRGHNTHHQIETVFKAFGRALRMAIELD 183 Query: 185 PRAAGTIPSTKGSL 198 R AG +PSTKG L Sbjct: 184 ERMAGQMPSTKGCL 197 >NMB1583 [E] COG0131 Imidazoleglycerol-phosphate dehydratase Nme Neisseria meningitidis MC58 Length = 305 Score = 313 bits (802), Expect = 2e-85, Method: Compositional matrix adjust. Identities = 147/194 (75%), Positives = 167/194 (86%) Query: 5 RTAEVVRNTNETQIRVAINLDGTGQQKLDTGVPFLDHMLDQIARHGLIDLDIHAKGDLHI 64 R+ V RNT ETQI V+INLDG+G+ +LDTGVPFL+HM+DQIARHG+ID+DI KGDLHI Sbjct: 110 RSVTVNRNTCETQITVSINLDGSGKSRLDTGVPFLEHMIDQIARHGMIDIDISCKGDLHI 169 Query: 65 DAHHTVEDVGITLGMAFAKAIGDKKGIRRYGHAYVPLDEALSRVVIDFSGRPGLEYHIPF 124 D HHT ED+GITLG A +A+GDKKGIRRYGH+YVPLDEALSRVVID SGRPGL Y+I F Sbjct: 170 DDHHTAEDIGITLGQAIRQALGDKKGIRRYGHSYVPLDEALSRVVIDLSGRPGLVYNIEF 229 Query: 125 TRSMIGSFDVDLTSEFFHGFVNHAQVTLHVDNLRGVNAHHQAETVFKAFGRALRMAVELD 184 TR++IG FDVDL EFFHG VNH+ +TLH+DNL G NAHHQAETVFKAFGRALRMAVE D Sbjct: 230 TRALIGRFDVDLFEEFFHGIVNHSMMTLHIDNLSGKNAHHQAETVFKAFGRALRMAVEHD 289 Query: 185 PRAAGTIPSTKGSL 198 PR AG PSTKG+L Sbjct: 290 PRMAGQTPSTKGTL 303 >NMA1772 [E] COG0131 Imidazoleglycerol-phosphate dehydratase NmA Neisseria meningitidis Z2491 Length = 305 Score = 313 bits (802), Expect = 2e-85, Method: Compositional matrix adjust. Identities = 147/194 (75%), Positives = 167/194 (86%) Query: 5 RTAEVVRNTNETQIRVAINLDGTGQQKLDTGVPFLDHMLDQIARHGLIDLDIHAKGDLHI 64 R+ V RNT ETQI V+INLDG+G+ +LDTGVPFL+HM+DQIARHG+ID+DI KGDLHI Sbjct: 110 RSVTVNRNTCETQITVSINLDGSGKSRLDTGVPFLEHMIDQIARHGMIDIDISCKGDLHI 169 Query: 65 DAHHTVEDVGITLGMAFAKAIGDKKGIRRYGHAYVPLDEALSRVVIDFSGRPGLEYHIPF 124 D HHT ED+GITLG A +A+GDKKGIRRYGH+YVPLDEALSRVVID SGRPGL Y+I F Sbjct: 170 DDHHTAEDIGITLGQAIRQALGDKKGIRRYGHSYVPLDEALSRVVIDLSGRPGLVYNIEF 229 Query: 125 TRSMIGSFDVDLTSEFFHGFVNHAQVTLHVDNLRGVNAHHQAETVFKAFGRALRMAVELD 184 TR++IG FDVDL EFFHG VNH+ +TLH+DNL G NAHHQAETVFKAFGRALRMAVE D Sbjct: 230 TRALIGRFDVDLFEEFFHGIVNHSMMTLHIDNLSGKNAHHQAETVFKAFGRALRMAVEHD 289 Query: 185 PRAAGTIPSTKGSL 198 PR AG PSTKG+L Sbjct: 290 PRMAGQTPSTKGTL 303 >all4390 [E] COG0131 Imidazoleglycerol-phosphate dehydratase Nos Nostoc sp. PCC 7120 Length = 209 Score = 245 bits (626), Expect = 4e-65, Method: Compositional matrix adjust. Identities = 119/197 (60%), Positives = 143/197 (72%) Query: 2 STPRTAEVVRNTNETQIRVAINLDGTGQQKLDTGVPFLDHMLDQIARHGLIDLDIHAKGD 61 S PR A V R T ET ++V +NLDGTG K TG+PFLDHML QI+ HGLIDLD+ AKGD Sbjct: 13 SVPRIASVHRITGETNVQVTVNLDGTGICKAATGIPFLDHMLHQISSHGLIDLDVQAKGD 72 Query: 62 LHIDAHHTVEDVGITLGMAFAKAIGDKKGIRRYGHAYVPLDEALSRVVIDFSGRPGLEYH 121 ID HHT EDVGITLG A AKA+GD+KGI R+G+ PLDEAL +V +DFSGRP L Y Sbjct: 73 WEIDDHHTNEDVGITLGQALAKALGDRKGIVRFGNFLAPLDEALVQVALDFSGRPHLSYG 132 Query: 122 IPFTRSMIGSFDVDLTSEFFHGFVNHAQVTLHVDNLRGVNAHHQAETVFKAFGRALRMAV 181 + +G++D L EFF VNH+Q+TLH+ L G+N+HH E FKAF RA RMA+ Sbjct: 133 LQIPTERVGTYDTQLVREFFVALVNHSQMTLHIRQLDGINSHHIIEATFKAFARAARMAI 192 Query: 182 ELDPRAAGTIPSTKGSL 198 E+DPR AGTIPS+KG L Sbjct: 193 EVDPRRAGTIPSSKGVL 209