BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0024.0020.p (360 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2951 [E] COG0079 Histidinol-phosphate/aromatic aminotransfera... 407 e-113 NMA1771 [E] COG0079 Histidinol-phosphate/aromatic aminotransfera... 280 4e-75 NMB1582 [E] COG0079 Histidinol-phosphate/aromatic aminotransfera... 273 4e-73 aq_2084 [E] COG0079 Histidinol-phosphate/aromatic aminotransfera... 214 2e-55 DR2461 [E] COG0079 Histidinol-phosphate/aromatic aminotransferas... 172 8e-43 >RSc2951 [E] COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Rso Ralstonia solanacearum Length = 374 Score = 407 bits (1047), Expect = e-113, Method: Compositional matrix adjust. Identities = 216/362 (59%), Positives = 268/362 (74%), Gaps = 3/362 (0%) Query: 1 VDDLVANVIRPLVRGWQSYHVPSAEGRVKLDAMENPYLLPPALREELAQRLAALELNRYP 60 +DDL+ ++R VR +YHVP A G VKLDAMENPY LP LR+ L +RLA + LNRYP Sbjct: 11 LDDLLGRIVRDDVRAMGAYHVPDASGMVKLDAMENPYHLPAMLRDALGKRLAEVALNRYP 70 Query: 61 VPSYTRLKAAICAQLGVPAGYDVLLGNGSDELITMLSVACAIPGRTILAPEPGFVMYGVS 120 VP+ LKA + + VPAG DVLLGNGSDE+I+++++A A PG T+LAP PGFVMY +S Sbjct: 71 VPTADALKAQLKRVMRVPAGADVLLGNGSDEIISLIAIAAAKPGATVLAPVPGFVMYAMS 130 Query: 121 AKMAGLDYVGVPLRADLTLDLPAMLAAIEQHKPVITWLGYPNNPTGTLYPMADV---LRI 177 A++ GL +VGVPLRADLTLD AMLAA+ +H+P + +L YPNNPTG L+ AD+ LR Sbjct: 131 AQLMGLKFVGVPLRADLTLDREAMLAAMAEHQPAVIYLAYPNNPTGNLFDAADMDALLRA 190 Query: 178 IEAAAPYGLVVVDEAYQPFAASTLMPALPQHNNLVVMRTVSKLGLAGIRLGYLSAAPALL 237 LVVVDEAYQPFA + MP LP+ ++L+VMRTVSKLGLAGIRLGY++ P + Sbjct: 191 ARGPVCQSLVVVDEAYQPFAQHSWMPRLPEFDHLLVMRTVSKLGLAGIRLGYVAGHPKWI 250 Query: 238 RELDKVRPPYNVNMLTEAAALFVLEHLQVLEAQAAQLREARSVLAAELAALEGVEVFPSA 297 ELDKVRPPYNVN+LTEA A FVL+H+ VL+AQAA LR R+ L L+A GV VFPSA Sbjct: 251 AELDKVRPPYNVNVLTEATAAFVLDHVDVLDAQAATLRAERTRLIDALSAQPGVTVFPSA 310 Query: 298 ANFILIRVPEADKVCAALLARRVLVKNAGRMHVLLQNCLRITVSTDEENAIFLTALKDAL 357 ANF+L+RVP+A + LL RRVLVKN +MH LL NCLR+TVS EENA FL A +L Sbjct: 311 ANFLLLRVPDAAGLFERLLKRRVLVKNVSKMHPLLANCLRVTVSNPEENAQFLDAFAASL 370 Query: 358 RE 359 ++ Sbjct: 371 QD 372 >NMA1771 [E] COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase NmA Neisseria meningitidis Z2491 Length = 365 Score = 280 bits (716), Expect = 4e-75, Method: Compositional matrix adjust. Identities = 152/355 (42%), Positives = 217/355 (61%), Gaps = 8/355 (2%) Query: 5 VANVIRPLVRGWQSYHVPSAE-GRVKLDAMENPYLLPPALREELAQ----RLAALELNRY 59 V + IR ++ +Y + G KLD+ME+P + P A E L Q RLAA ++ Y Sbjct: 4 VRSFIRDDIQAMSAYQIADVPPGFAKLDSMESP-VHPFAGHETLLQEWQARLAAAPIHLY 62 Query: 60 PVPSYTRLKAAICAQLGVPAGYDVLLGNGSDELITMLSVACAIPGRTILAPEPGFVMYGV 119 P PS + L+ A+ + +P D+ LGNGSDELI +++ A PG +LA EP FVMY Sbjct: 63 PNPSGSGLQEALRSAFDIPDCADIALGNGSDELIQFITMLTAKPGAAMLAAEPSFVMYRH 122 Query: 120 SAKMAGLDYVGVPLRADLTLDLPAMLAAIEQHKPVITWLGYPNNPTGTLYPMADVLRIIE 179 +A + G+DYVGVPL D TL+LPA+L A+ +H+P +T++ YPNNPTG + A++ +IE Sbjct: 123 NAALYGMDYVGVPLNGDFTLNLPAVLEAVRKHRPALTFIAYPNNPTGVCFTRAEIEAVIE 182 Query: 180 AAAPYGLVVVDEAYQPFAASTLMPALPQHNNLVVMRTVSKLGLAGIRLGYLSAAPALLRE 239 A+ G+VVVDEAY F + +P NL+VMRTVSK+G AG+R+GY + P ++ E Sbjct: 183 ASD--GIVVVDEAYGAFNGDSFLPQAGSIPNLIVMRTVSKIGFAGLRIGYAAGCPEVIGE 240 Query: 240 LDKVRPPYNVNMLTEAAALFVLEHLQVLEAQAAQLREARSVLAAELAALEGVEVFPSAAN 299 L K+ PPYN+N L+ A L+H ++ A L+ R + AEL + + FPS AN Sbjct: 241 LQKILPPYNMNQLSLTTAKLALQHYGIISANIDSLKNERERMFAELGKICRLNTFPSQAN 300 Query: 300 FILIRVPEADKVCAALLARRVLVKNAGRMHVLLQNCLRITVSTDEENAIFLTALK 354 FI IRVP+AD + L R+LVK H LL++CLRITV + +N L ++ Sbjct: 301 FITIRVPDADLLFDTLKQNRILVKKLHGAHPLLEHCLRITVGSPAQNDAVLNIIR 355 >NMB1582 [E] COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Nme Neisseria meningitidis MC58 Length = 365 Score = 273 bits (699), Expect = 4e-73, Method: Compositional matrix adjust. Identities = 149/355 (41%), Positives = 216/355 (60%), Gaps = 8/355 (2%) Query: 5 VANVIRPLVRGWQSYHVPSAE-GRVKLDAMENPYLLPPALREELAQ----RLAALELNRY 59 V + IR ++ +Y + G KLD+ME+P + P A E L Q RLAA ++ Y Sbjct: 4 VRSFIRDDIQAMSAYQIADVPPGFAKLDSMESP-VHPFAGHETLLQEWQARLAAAPIHLY 62 Query: 60 PVPSYTRLKAAICAQLGVPAGYDVLLGNGSDELITMLSVACAIPGRTILAPEPGFVMYGV 119 P PS + L+ A+ + +P D+ LGNGSDELI +++ A PG +LA EP FVMY Sbjct: 63 PNPSGSGLQEALRSAFDIPDCADIALGNGSDELIQFITMLTAKPGAAMLAAEPSFVMYRH 122 Query: 120 SAKMAGLDYVGVPLRADLTLDLPAMLAAIEQHKPVITWLGYPNNPTGTLYPMADVLRIIE 179 +A + G+DYVGVPL D TL+LPA+L A+ +H+P +T++ YPNNPTG + A++ +IE Sbjct: 123 NAALYGMDYVGVPLNGDFTLNLPAVLEAVRKHRPALTFIAYPNNPTGVCFTRAEIEAVIE 182 Query: 180 AAAPYGLVVVDEAYQPFAASTLMPALPQHNNLVVMRTVSKLGLAGIRLGYLSAAPALLRE 239 A+ G+VVVDEAY F + +P + NL+V+RT+SK+G AG+R+GY + P ++ E Sbjct: 183 ASD--GIVVVDEAYGAFNGDSFLPQAGRIPNLIVLRTLSKIGFAGLRIGYAAGCPEVIGE 240 Query: 240 LDKVRPPYNVNMLTEAAALFVLEHLQVLEAQAAQLREARSVLAAELAALEGVEVFPSAAN 299 L K+ PPYN+N L+ A L H ++ A L+ R + AEL + + F S AN Sbjct: 241 LQKILPPYNMNQLSLTTAKLALRHYGIISANIDSLKNERERMFAELGKICRLNTFSSQAN 300 Query: 300 FILIRVPEADKVCAALLARRVLVKNAGRMHVLLQNCLRITVSTDEENAIFLTALK 354 FI IRVP+AD + L R+LVK H LL++CLRITV + +N L ++ Sbjct: 301 FITIRVPDADLLFDTLKQNRILVKKLHGAHPLLEHCLRITVGSPAQNDAVLNIIR 355 >aq_2084 [E] COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Aae Aquifex aeolicus Length = 354 Score = 214 bits (546), Expect = 2e-55, Method: Compositional matrix adjust. Identities = 124/348 (35%), Positives = 191/348 (54%), Gaps = 7/348 (2%) Query: 13 VRGWQSYHVPSAEGRVKLDAMENPYLLPPALREELAQRLAALELNRYPVPSYTRLKAAIC 72 ++ ++Y V+L + E PY P +++ + L + LN+YP P LKA + Sbjct: 6 IKELEAYKTEVTPASVRLSSNEFPYDFPEEIKQRALEELKKVPLNKYPDPEAKELKAVLA 65 Query: 73 AQLGVPAGYDVLLGNGSDELITMLSVACAIPGRTILAPEPGFVMYGVSAKMAGLDYVGVP 132 GV +++LGNGSDELI LS+A + P P F MY +SAK+ G V V Sbjct: 66 DFFGVKEE-NLVLGNGSDELIYYLSIAIGELYIPVYIPVPTFPMYEISAKVLGRPLVKVQ 124 Query: 133 LRADLTLDLPAMLAAIEQHKPVITWLGYPNNPTGTLYPMADVLRIIEAAAPYGLVVVDEA 192 L + +DL + IE+ KPV+ + YPNNPTG L+ + I V+DEA Sbjct: 125 LDENFDIDLERSIELIEKEKPVLGYFAYPNNPTGNLFSRGKIEEIRNRGV---FCVIDEA 181 Query: 193 YQPFAASTLMPALPQHNNLVVMRTVSKLGLAGIRLGYLSAAPALLRELDKVRPPYNVNML 252 Y ++ T + + + VV+RT+SK+G+A +R+G L ++ E++KVR P+NV Sbjct: 182 YYHYSGETFLEDALKREDTVVLRTLSKIGMASLRVGILIGKGEIVSEINKVRLPFNVTYP 241 Query: 253 TEA-AALFVLEHLQVLEAQAAQLREARSVLAAELAALEGVEVFPSAANFILIRVPE-ADK 310 ++ A + + E + L + ++ + R + E+ +EGVEVFPS ANF+L R P A + Sbjct: 242 SQVMAKVLLTEGREFLMEKIQEVVKERERMYDEMKKIEGVEVFPSKANFLLFRTPYPAHE 301 Query: 311 VCAALLARRVLVKNAGRMHVLLQNCLRITVSTDEENAIFLTALKDALR 358 V LL R VLV+N M LQ CLR++V EEN FL AL+++++ Sbjct: 302 VYQELLKRDVLVRNVSYMEG-LQKCLRVSVGKPEENNKFLEALEESIK 348 >DR2461 [E] COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Dra Deinococcus radiodurans Length = 361 Score = 172 bits (437), Expect = 8e-43, Method: Compositional matrix adjust. Identities = 117/347 (33%), Positives = 176/347 (50%), Gaps = 5/347 (1%) Query: 9 IRPLVRGWQSYHVPSAEGRVKLDAMENPYLLPPALREELAQRLAALELNRYPVPSYTRLK 68 +R VR +Y + KLD ENPY PP L+++ A+R+ A NRYP L+ Sbjct: 14 VRQAVRDIPAYPFTPIDVPYKLDQNENPYDFPPELKQKAAERMLAHPWNRYPDLHADTLR 73 Query: 69 AAICAQLGVPAGYDVLLGNGSDELITMLSVACAIPGRTILAPEPGFVMYGVSAKMAGLDY 128 AAI G A V++ GS+ LI +L+ I G+T+L +P F +Y + A M G + Sbjct: 74 AAIAGYEGWDAA-GVVITPGSNVLIKILTELGGI-GQTVLTTDPTFSVYTLEAAMLGAEL 131 Query: 129 VGVPLRADLTLDLPAMLAAIEQHKPVITWLGYPNNPTGTLYPMADVLRIIEAAAPYGLV- 187 V PL D +L + A L A+ H P + ++ P+ PTG DV R++E A G V Sbjct: 132 VLTPLNPDFSLPVEATLQALAAHAPGVFYVTQPHAPTGHSDRPEDVRRVVEVADRLGWVT 191 Query: 188 VVDEAYQPFAASTLMPALPQHNNLVVMRTVSK-LGLAGIRLGYLSAAPALLRELDKVRPP 246 V+DEAY +A + + +++ +RT SK GLAG+R GYL P L L K+ Sbjct: 192 VIDEAYSQYAGTDYRELVRAGKHVLSLRTFSKAWGLAGVRAGYLLTNPELAGHLQKLVSA 251 Query: 247 YNVNMLTEAAALFVLEHLQVLEAQAAQLREARSVLAAELAALEGVEVFPSAANFILIRVP 306 + +N LT+A LEH + + + A+ R + A + +FPS NF L++ P Sbjct: 252 FTINFLTQAVIETALEHPEYMRERVAEAIAERGRIYAAVQGHPTCTIFPSNTNFFLLKTP 311 Query: 307 EADKVCAALLARRVLVKNAGRMHVLLQNCLRITVSTDEENAIFLTAL 353 +AD LL ++ + ++ L CLRI V T EN + A+ Sbjct: 312 DADAAYRHLLEHGIVCRRQDKLRG-LDGCLRIAVGTPAENDALIAAI 357