BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0023.0018.p (440 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA2217 [C] COG1012 NAD-dependent aldehyde dehydrogenases Pae Pse... 582 e-166 PA1253 [C] COG1012 NAD-dependent aldehyde dehydrogenases Pae Pse... 544 e-154 RSp0827 [C] COG1012 NAD-dependent aldehyde dehydrogenases Rso Ra... 420 e-117 CC2791 [C] COG1012 NAD-dependent aldehyde dehydrogenases Ccr Cau... 413 e-115 AGl3116 [C] COG1012 NAD-dependent aldehyde dehydrogenases Atu Ag... 409 e-114 >PA2217 [C] COG1012 NAD-dependent aldehyde dehydrogenases Pae Pseudomonas aeruginosa Length = 527 Score = 582 bits (1501), Expect = e-166, Method: Compositional matrix adjust. Identities = 293/439 (66%), Positives = 348/439 (79%), Gaps = 1/439 (0%) Query: 1 VARETALPATPRLAGERARTSGQMRLFAKVLRRGDFYGARIDTALPQRQPLPRPDIRQYK 60 V RETALPAT R+ GER+RTSGQ+RLFA+VLRRGDF+GARID A P+R+PLPR D+RQ + Sbjct: 89 VCRETALPAT-RIQGERSRTSGQLRLFAEVLRRGDFHGARIDRARPERKPLPRVDLRQCR 147 Query: 61 IGVGPVAVFGASNFPLAFSVAGGDTAAALAAGCPVVFKAHSGHLVTSELVANAIERAVKK 120 IG+GPVAVFGASNFPLAFS AGGDTAAALAAGCPVVFKAHSGH+ T+E VA AI RA ++ Sbjct: 148 IGLGPVAVFGASNFPLAFSTAGGDTAAALAAGCPVVFKAHSGHMATAERVAAAILRAAER 207 Query: 121 TGMPAGTFNMIYGDRVGAQLVKSAGIQAVGFTGSLRGGRALCDMAAARPQPIPVFAEMSS 180 TGMPAG FNMIYG VG +LV+ IQAVGFTGSL+GGRALCDMAAAR QPIPVFAEMSS Sbjct: 208 TGMPAGVFNMIYGGGVGERLVRHPAIQAVGFTGSLKGGRALCDMAAARAQPIPVFAEMSS 267 Query: 181 INPIILMSEALKLRGDAIAKDLAGSVTVGVGQLCTSPGLLLGVRSPELTAFIEKLSAAFG 240 INP++L+ ALK RG+A+A +L+ SV +G GQ CT+PGL++G+RS + +AF+E+ +A Sbjct: 268 INPVVLLPAALKKRGEAVADELSASVVLGCGQFCTNPGLVIGIRSAQFSAFLERFAARMD 327 Query: 241 GTNPATMLNSGGLTHYNGGVARLTQLPGVKVIATGGTSYTQAVPHLFKADAALLFSKEAP 300 TMLN+G L Y G+A L P V+ +A QA P LF+AD +LL + Sbjct: 328 DQPAQTMLNTGTLASYEKGLAALHAHPRVRHLAGQPQEGRQARPQLFQADVSLLLEGDEL 387 Query: 301 LEEEVFGPATVIVELESREQLLDFAAKMNGQLTATLQAEIGDLQGNQDLIAILEQKAGRL 360 L+EEVFGPA+V+VE+ +L ++GQLTATL AE DL DL+ +LEQKAGRL Sbjct: 388 LQEEVFGPASVVVEVADHAELKRALHGLHGQLTATLIAEAEDLASFADLVPLLEQKAGRL 447 Query: 361 LLNGFPTGVEVCDAMVHGGPYPATSDARGTSVGTLAIERFLRPVCYQNYPDAMLPAALQN 420 LLNG+PTGVEVCDAMVHGGPYPATSDARGTSVGTLAI+RFLRPVCYQNYPDA LP AL++ Sbjct: 448 LLNGYPTGVEVCDAMVHGGPYPATSDARGTSVGTLAIDRFLRPVCYQNYPDAWLPEALKD 507 Query: 421 ANPLGLMRLVDGEQTRATV 439 NPLG+ RLVDG TRA V Sbjct: 508 GNPLGIARLVDGIVTRAAV 526 >PA1253 [C] COG1012 NAD-dependent aldehyde dehydrogenases Pae Pseudomonas aeruginosa Length = 526 Score = 544 bits (1402), Expect = e-154, Method: Compositional matrix adjust. Identities = 279/436 (63%), Positives = 334/436 (76%), Gaps = 2/436 (0%) Query: 1 VARETALPATPRLAGERARTSGQMRLFAKVLRRGDFYGARIDTALPQRQPLPRPDIRQYK 60 V RETALPA R+ GER RT+ Q+RLFA+VLRRGDF+G RID P R P PRPD+RQ++ Sbjct: 89 VRRETALPAA-RIEGERTRTANQLRLFAEVLRRGDFHGVRIDRGQPGRTP-PRPDLRQWR 146 Query: 61 IGVGPVAVFGASNFPLAFSVAGGDTAAALAAGCPVVFKAHSGHLVTSELVANAIERAVKK 120 IG+GPVAVFGASNFPLAFS AGGD+AAALAAGCPVV KAH GH+ T+E VA+AI +A Sbjct: 147 IGLGPVAVFGASNFPLAFSTAGGDSAAALAAGCPVVVKAHGGHMATAECVADAILQAAAD 206 Query: 121 TGMPAGTFNMIYGDRVGAQLVKSAGIQAVGFTGSLRGGRALCDMAAARPQPIPVFAEMSS 180 +GMP G FNM+YG VG LV+ I+AVGFTGSL+GGRALCD+AAARPQPIPVFAEMSS Sbjct: 207 SGMPDGVFNMVYGSGVGEALVRHPAIRAVGFTGSLKGGRALCDLAAARPQPIPVFAEMSS 266 Query: 181 INPIILMSEALKLRGDAIAKDLAGSVTVGVGQLCTSPGLLLGVRSPELTAFIEKLSAAFG 240 INP++++ EAL+ RG +A++LA SVT+G GQ CT PGL+LG+RSP AF+ L A Sbjct: 267 INPLVVLPEALRRRGRQVAEELAASVTLGCGQFCTKPGLVLGLRSPGFDAFVAALGEALA 326 Query: 241 GTNPATMLNSGGLTHYNGGVARLTQLPGVKVIATGGTSYTQAVPHLFKADAALLFSKEAP 300 +MLN+G L Y G+ RL + PG++ +A QA P LFKAD LL + Sbjct: 327 ARPAQSMLNAGTLRSYVEGLQRLERHPGIRRLAGAPQEGRQAHPQLFKADVGLLLEGDEL 386 Query: 301 LEEEVFGPATVIVELESREQLLDFAAKMNGQLTATLQAEIGDLQGNQDLIAILEQKAGRL 360 L+EEVFGPATV+VE EQL ++GQL+ATL E DL L+ +LE+KAGRL Sbjct: 387 LQEEVFGPATVVVEAADEEQLARALDNLHGQLSATLIGEADDLAAFAGLVPLLERKAGRL 446 Query: 361 LLNGFPTGVEVCDAMVHGGPYPATSDARGTSVGTLAIERFLRPVCYQNYPDAMLPAALQN 420 L NG+PTGVEVCDAMVHGGPYPATSDARGTSVGTLAIERFLRP+CYQ+YPD++LP AL+N Sbjct: 447 LFNGYPTGVEVCDAMVHGGPYPATSDARGTSVGTLAIERFLRPLCYQDYPDSLLPDALKN 506 Query: 421 ANPLGLMRLVDGEQTR 436 ANPLGL+RLVDG TR Sbjct: 507 ANPLGLLRLVDGRSTR 522 >RSp0827 [C] COG1012 NAD-dependent aldehyde dehydrogenases Rso Ralstonia solanacearum Length = 528 Score = 420 bits (1080), Expect = e-117, Method: Compositional matrix adjust. Identities = 237/435 (54%), Positives = 296/435 (68%), Gaps = 5/435 (1%) Query: 4 ETALPATPRLAGERARTSGQMRLFAKVLRRGDFYGARIDTALPQRQPLPRPDIRQYKIGV 63 E+ALP PRL GER RT Q+RLFAKV+R GD GARID ALP+R+PLPR D+R +I + Sbjct: 91 ESALP-RPRLEGERGRTCNQLRLFAKVVRAGDAVGARIDPALPERKPLPRSDLRMRRIAM 149 Query: 64 GPVAVFGASNFPLAFSVAGGDTAAALAAGCPVVFKAHSGHLVTSELVANAIERAVKKTGM 123 GPVAVFGASNFPLAFSVAGGDTA+ALAAGCPVV KAH H TSELV AI+ AV + G+ Sbjct: 150 GPVAVFGASNFPLAFSVAGGDTASALAAGCPVVVKAHPAHPGTSELVGRAIQAAVAQCGL 209 Query: 124 PAGTFNMIYGDRVGA-QLVKSAGIQAVGFTGSLRGGRALCDMAAARPQPIPVFAEMSSIN 182 P G F+++ D A LV IQAVGFTGS GG+AL +A AR QPIPV+ E+S+IN Sbjct: 210 PEGVFSLVLADNEAAGALVADPRIQAVGFTGSRAGGQALLRIAQARAQPIPVYGELSAIN 269 Query: 183 PIILMSEALKLRGDAIAKDLAGSVTVGVGQLCTSPGLLLGVRSPELTAFIEKLSAAFGGT 242 P+ L+ +AL R A+ + GS+T+G GQ CT+PGLLL + P+L AF + A + Sbjct: 270 PVFLLPDALARRAAALGQQYVGSLTMGAGQFCTNPGLLLAIDGPDLDAFEAAAAEALQAS 329 Query: 243 NPATMLNSGGLTHYNGGVARLTQLPGVKVIATGGTSY--TQAVPHLFKADAALLFSKEAP 300 TML+SG Y+ GV RL V+ +A G S + F+ DA F + Sbjct: 330 AAQTMLSSGIHAAYSRGVERLAGEANVRCVARGQGSDAPNRGQAGFFRTDAE-SFRAQPA 388 Query: 301 LEEEVFGPATVIVELESREQLLDFAAKMNGQLTATLQAEIGDLQGNQDLIAILEQKAGRL 360 L +E+FG ++V + E+L A + GQLTATL + GD + L++ILE+KAGR+ Sbjct: 389 LHDEIFGATGLVVRCRNAEELKALAESLEGQLTATLHLDAGDTALARALLSILERKAGRI 448 Query: 361 LLNGFPTGVEVCDAMVHGGPYPATSDARGTSVGTLAIERFLRPVCYQNYPDAMLPAALQN 420 L NG+PTGVEVC AMVHGGP+PAT+D R TSVGT AIERFLRPVCYQ+ P +LPAAL++ Sbjct: 449 LANGWPTGVEVCHAMVHGGPWPATTDTRTTSVGTAAIERFLRPVCYQDLPAELLPAALRD 508 Query: 421 ANPLGLMRLVDGEQT 435 NP L RLVDG T Sbjct: 509 DNPQQLRRLVDGAWT 523 >CC2791 [C] COG1012 NAD-dependent aldehyde dehydrogenases Ccr Caulobacter vibrioides Length = 528 Score = 413 bits (1062), Expect = e-115, Method: Compositional matrix adjust. Identities = 234/436 (53%), Positives = 282/436 (64%), Gaps = 11/436 (2%) Query: 4 ETALPATPRLAGERARTSGQMRLFAKVLRRGDFYGARIDTALPQRQPLPRPDIRQYKIGV 63 ET LP PRL GER RT GQ+RLFA VLR G F ARID A+P R+PLPRPD+R + + Sbjct: 92 ETGLP-RPRLEGERGRTVGQLRLFAGVLRDGGFLEARIDPAMPDRKPLPRPDLRLRNVPL 150 Query: 64 GPVAVFGASNFPLAFSVAGGDTAAALAAGCPVVFKAHSGHLVTSELVANAIERAVKKTGM 123 GPVAVFGASNFPLAFSVAGGDTA+ALAAGCPV+ KAH H SELV AI+ AV G+ Sbjct: 151 GPVAVFGASNFPLAFSVAGGDTASALAAGCPVIVKAHPAHPGASELVGRAIQAAVAACGL 210 Query: 124 PAGTFNMIY--GDRVGAQLVKSAGIQAVGFTGSLRGGRALCDMAAARPQPIPVFAEMSSI 181 P G F +I+ G V LV ++A GFTGS RGG AL +A RP+PIP +AEMSSI Sbjct: 211 PPGVFALIHDSGYEVSQALVADPRVKAAGFTGSRRGGLALLAIAQGRPEPIPFYAEMSSI 270 Query: 182 NPIILMSEALKLRGDAIAKDLAGSVTVGVGQLCTSPGLLLGVRSPELTAFIEKLSAAFGG 241 NP+IL+ ALK R D IA D ++T+G GQ CT+PGL+L + PEL AFIE A Sbjct: 271 NPVILLPAALKARADKIAPDFVAALTLGAGQFCTNPGLILAIDGPELDAFIEAAGKAVEA 330 Query: 242 TNPATMLNSGGLTHYNGGVARLTQLPGVKVIATG-----GTSYTQAVPHLFKADAALLFS 296 + ML G + GVA LT V +A G G+ +A LF AA + Sbjct: 331 APASVMLTPGICQAFAHGVAALTDAAEVTTVARGVPGPDGSHTGRAA--LFSVTAADFLA 388 Query: 297 KEAPLEEEVFGPATVIVELESREQLLDFAAKMNGQLTATLQAEIGDLQGNQDLIAILEQK 356 L EEVFG A+++V + +L A + GQLT L + D L+ LE K Sbjct: 389 NPH-LHEEVFGAASLVVRCAGQAELEAVIAALEGQLTIALHMDEADHGIAGALLPALELK 447 Query: 357 AGRLLLNGFPTGVEVCDAMVHGGPYPATSDARGTSVGTLAIERFLRPVCYQNYPDAMLPA 416 AGR+L+NGF TGVEV AMVHGGP+P+TSD R TSVGTLAI RFLRPV YQN P+A+LPA Sbjct: 448 AGRILVNGFGTGVEVAPAMVHGGPFPSTSDGRTTSVGTLAIARFLRPVSYQNLPEALLPA 507 Query: 417 ALQNANPLGLMRLVDG 432 L+ NPLG++R VDG Sbjct: 508 ELKTQNPLGVVRRVDG 523 >AGl3116 [C] COG1012 NAD-dependent aldehyde dehydrogenases Atu Agrobacterium tumefaciens strain C58 (Cereon) Length = 534 Score = 409 bits (1052), Expect = e-114, Method: Compositional matrix adjust. Identities = 220/418 (52%), Positives = 280/418 (66%), Gaps = 5/418 (1%) Query: 4 ETALPATPRLAGERARTSGQMRLFAKVLRRGDFYGARIDTALPQRQPLPRPDIRQYKIGV 63 ET LPA RL GER RT GQ+ LFA +R+GD+ R D ALP RQPLPRPDIR + + Sbjct: 120 ETGLPAG-RLQGERGRTVGQLHLFASHIRKGDYLDRRHDEALPDRQPLPRPDIRLMQRPI 178 Query: 64 GPVAVFGASNFPLAFSVAGGDTAAALAAGCPVVFKAHSGHLVTSELVANAIERAVKKTGM 123 GPVAVFGASNFPLAFS AGGDTAAALAAGCPVV K HS H T E+VA A+ AVKK + Sbjct: 179 GPVAVFGASNFPLAFSTAGGDTAAALAAGCPVVVKGHSAHPGTGEIVAEAVLAAVKKHNL 238 Query: 124 PAGTFNMIYGDR--VGAQLVKSAGIQAVGFTGSLRGGRALCDMAAARPQPIPVFAEMSSI 181 G F++I G R VG+ LV+ I+AVGFTGSL GGRAL D+ A RP+PIP F E+ S+ Sbjct: 239 HPGVFSLIQGGRRDVGSALVQHPRIKAVGFTGSLAGGRALFDLCAQRPEPIPFFGELGSV 298 Query: 182 NPIILMSEALKLRGDAIAKDLAGSVTVGVGQLCTSPGLLLGVRSPELTAFIEKLSAAFGG 241 NP+ L+ EA+ RG+AIAK AGS+T+G GQ CT+PG+ + + S + A E AA Sbjct: 299 NPMFLLPEAVAARGEAIAKGWAGSLTMGAGQFCTNPGIAV-ILSEQADAVAETARAALSE 357 Query: 242 TNPATMLNSGGLTHYNGGVARLTQLPGVKVIATGGTSYTQAVPHLFKADAALLFSKEAPL 301 P ML G Y G R+ GV+ + T + A P+L++ + A L Sbjct: 358 VGPQVMLTDGIAAAYRDGRDRIAAGNGVRDVLTTTCNLRNATPYLYRVAGKDWVANHA-L 416 Query: 302 EEEVFGPATVIVELESREQLLDFAAKMNGQLTATLQAEIGDLQGNQDLIAILEQKAGRLL 361 EEVFGP +IV ++S E++L+ A GQLTAT+ + GD + + L+ ILE+KAGR+L Sbjct: 417 AEEVFGPLGLIVTVDSAEEMLEVAKSFEGQLTATMHLDAGDAELGRKLLPILERKAGRVL 476 Query: 362 LNGFPTGVEVCDAMVHGGPYPATSDARGTSVGTLAIERFLRPVCYQNYPDAMLPAALQ 419 NGFPTGVEV +AMVHGGPYPA+++ TSVGT++I RF+RPV YQN P +LP ++ Sbjct: 477 ANGFPTGVEVSEAMVHGGPYPASTNFGATSVGTMSIRRFMRPVSYQNIPSDVLPEDIR 534