BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0274.p (313 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value PA2536 [R] COG4589 Predicted CDP-diglyceride synthetase/phosphat... 398 e-111 PM2002 [R] COG4589 Predicted CDP-diglyceride synthetase/phosphat... 369 e-102 SMc02157 Non COG 332 1e-90 YPO2816 [R] COG4589 Predicted CDP-diglyceride synthetase/phospha... 231 2e-60 VC1936 [R] COG4589 Predicted CDP-diglyceride synthetase/phosphat... 225 1e-58 >PA2536 [R] COG4589 Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase Pae Pseudomonas aeruginosa Length = 311 Score = 398 bits (1023), Expect = e-111, Method: Compositional matrix adjust. Identities = 202/308 (65%), Positives = 250/308 (81%) Query: 4 QDTLFALFGGVFAVLALASSVGGLLRWRLAGRSSSVIDNLNARIKAWWWMIGALAIAFWI 63 + + LFGG+ A+L LAS VG +L+WR ++VIDNLNARI AWW M+ + AFW+ Sbjct: 2 NEQTWMLFGGIGALLLLASLVGFVLKWRAGPGPNAVIDNLNARINAWWAMVLVIGFAFWL 61 Query: 64 GKTGVVVLFAFISLQALREFISVTYTRVGDHRALLWCFFVFLPLQYVLIGMDWYGLFSIL 123 G+ V++LF +S ALREFI++T TR D+ AL+ F+ LP+QY+LI +DWY +FSI Sbjct: 62 GQAAVILLFYGVSFYALREFITLTPTRRSDYPALVAAFYFVLPMQYLLIYIDWYSMFSIF 121 Query: 124 IPVYAFLLLPISASLSTDTKHFLERAAKVQWGLMICVYCISHVPALLTLPIEGFEGRNLQ 183 IPVY FLLLPI ASL DTKHFLERA+KVQWGLM+ V+CIS VPALLTL I GFEGRNL Sbjct: 122 IPVYVFLLLPILASLGGDTKHFLERASKVQWGLMLAVFCISFVPALLTLDIPGFEGRNLL 181 Query: 184 LIVFLVLTVQSSDVFQYVWGKLFGKRKLAPQISPSKTLEGLVGGVLTSTAVGAALYWITP 243 LI +LV+ VQ SDV QY+ GKLFGKRK+AP +SPSKT+EG VGG+ +TA+GA+L+WITP Sbjct: 182 LIAYLVIVVQLSDVMQYICGKLFGKRKIAPNLSPSKTVEGFVGGIALATAIGASLWWITP 241 Query: 244 FNVWQAALVALTINILGFFGGFVLSAIKRDRGLKDWGAMIEGHGGMLDRVDSISFSAPIF 303 FN+WQAAL+AL IN+LGFFGG V+SAIKRDRG+KDWG MIEGHGGMLDR+DS+ F+APIF Sbjct: 242 FNLWQAALIALLINLLGFFGGLVMSAIKRDRGVKDWGHMIEGHGGMLDRLDSVCFAAPIF 301 Query: 304 FHILRYWW 311 FH++RYWW Sbjct: 302 FHVVRYWW 309 >PM2002 [R] COG4589 Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase Pmu Pasteurella multocida Length = 309 Score = 369 bits (946), Expect = e-102, Method: Compositional matrix adjust. Identities = 177/305 (58%), Positives = 230/305 (75%), Gaps = 1/305 (0%) Query: 9 ALFGGVFAVLALASSVGGLLRWRLA-GRSSSVIDNLNARIKAWWWMIGALAIAFWIGKTG 67 LF G+ L LAS++G L+W++ +VIDNLNARI AWW MI + A +IG Sbjct: 5 TLFWGLMFTLILASAIGYTLKWKVGFSTPHAVIDNLNARINAWWVMILIIFAAAFIGFYA 64 Query: 68 VVVLFAFISLQALREFISVTYTRVGDHRALLWCFFVFLPLQYVLIGMDWYGLFSILIPVY 127 V+ LF IS ALREF+S+ Y R GDH AL CF+V LP+QY + +DW+ +F+I IPVY Sbjct: 65 VIALFFIISFMALREFLSLIYIRRGDHLALAACFYVILPVQYYFVAIDWFSMFTIFIPVY 124 Query: 128 AFLLLPISASLSTDTKHFLERAAKVQWGLMICVYCISHVPALLTLPIEGFEGRNLQLIVF 187 AFL LPI ++L D HFL+R+ KVQW +MI V+CISH+PA+LTL I GFE +NL L++F Sbjct: 125 AFLFLPILSALLGDASHFLDRSTKVQWAIMISVFCISHIPAILTLDIVGFENKNLLLMIF 184 Query: 188 LVLTVQSSDVFQYVWGKLFGKRKLAPQISPSKTLEGLVGGVLTSTAVGAALYWITPFNVW 247 L+L VQSSDV QYVWGKLFGK K+AP +SPSKT+EG GG+L+++ +G LYW+TPF+ Sbjct: 185 LILVVQSSDVLQYVWGKLFGKHKIAPTLSPSKTVEGFAGGILSASILGGLLYWLTPFSPL 244 Query: 248 QAALVALTINILGFFGGFVLSAIKRDRGLKDWGAMIEGHGGMLDRVDSISFSAPIFFHIL 307 QA L++L I ++GF GG V+SAIKR G+KDWG MI GHGGMLDR+DS+ F+APIFFH++ Sbjct: 245 QAFLMSLLICLMGFLGGLVMSAIKRSMGVKDWGNMISGHGGMLDRMDSLCFAAPIFFHVV 304 Query: 308 RYWWV 312 RY+WV Sbjct: 305 RYYWV 309 >SMc02157 Non COG Length = 313 Score = 332 bits (850), Expect = 1e-90, Method: Compositional matrix adjust. Identities = 174/313 (55%), Positives = 224/313 (71%), Gaps = 1/313 (0%) Query: 1 MTPQDTLFALFGGVFAVLALASSVGGLLRWRLAGRSS-SVIDNLNARIKAWWWMIGALAI 59 M+ D LF LF G+ A+L AS +G +L R + + IDNLNARI+AWW MI A+ Sbjct: 1 MSLNDKLFILFAGIAALLGAASLIGFVLARRATSETGRATIDNLNARIRAWWVMIAIFAV 60 Query: 60 AFWIGKTGVVVLFAFISLQALREFISVTYTRVGDHRALLWCFFVFLPLQYVLIGMDWYGL 119 +F +G+ +VLFA S LREF+S+T TR DH L+ F+V LPLQY LI +DWY L Sbjct: 61 SFTLGRGVTLVLFALTSFYTLREFVSLTPTRAADHLPLVASFYVLLPLQYWLISIDWYAL 120 Query: 120 FSILIPVYAFLLLPISASLSTDTKHFLERAAKVQWGLMICVYCISHVPALLTLPIEGFEG 179 F+ILIPVY FLLLP ++L DT+ FL R +++QWGLM+ VYCISH PALLTL I G G Sbjct: 121 FTILIPVYGFLLLPSLSALKGDTEQFLLRVSRIQWGLMLTVYCISHAPALLTLDIPGRAG 180 Query: 180 RNLQLIVFLVLTVQSSDVFQYVWGKLFGKRKLAPQISPSKTLEGLVGGVLTSTAVGAALY 239 L+ FL+ Q SDV QYV+GKLFG+ K+AP +SPSKT+EGL GG L++ A GAAL+ Sbjct: 181 EGFLLLFFLITIAQFSDVMQYVFGKLFGRTKVAPVVSPSKTVEGLAGGGLSAVAAGAALW 240 Query: 240 WITPFNVWQAALVALTINILGFFGGFVLSAIKRDRGLKDWGAMIEGHGGMLDRVDSISFS 299 WITPF +AA +A I +GF GG LSA+KR G+KDWG+MI GHGG+LDR+DS+SF+ Sbjct: 241 WITPFTPLEAAAMAFAIVAMGFLGGLALSAVKRSMGVKDWGSMISGHGGVLDRMDSLSFA 300 Query: 300 APIFFHILRYWWV 312 AP+FFH+ RY++ Sbjct: 301 APVFFHLTRYFYT 313 >YPO2816 [R] COG4589 Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase Ype Yersinia pestis Length = 309 Score = 231 bits (588), Expect = 2e-60, Method: Compositional matrix adjust. Identities = 131/310 (42%), Positives = 191/310 (61%), Gaps = 8/310 (2%) Query: 5 DTLFALFGGVFAVLALASSVGGLLRWRLAGRSSSVIDNLNARIKAWWWMIGALAIAFWIG 64 TL+ GG+F+VL LA+ + +L+ R L RI +WW +I ++A Sbjct: 6 QTLYYCLGGIFSVLLLATIIIFVLK---KCRPQRDWLELQQRINSWWVIICLFSLAMLSP 62 Query: 65 KTGVVVLFAFISLQALREFISVTYTRVGDHRALLWCFFVFLPLQYVLIGMDWYGLFSILI 124 K + F FIS +L+E++++ TR D LLW + +PLQYV IGM WYG+F I I Sbjct: 63 KWLALTFFGFISFLSLKEYLTLAPTRRSDSVPLLW-MYAAIPLQYVWIGMSWYGMFIIFI 121 Query: 125 PVYAFLLLPISASLSTDTKHFLERAAKVQWGLMICVYCISHVPALLTLPIEGFEGR-NLQ 183 P+Y FL LP L DTK FL A+ + WG+M V+ +SHV LLTLP G + + Sbjct: 122 PIYVFLFLPARMVLVGDTKGFLHSASIMHWGMMATVFALSHVAYLLTLP--GVDAKAGAL 179 Query: 184 LIVFLVLTVQSSDVFQYVWGKLFGKRKLAPQISPSKTLEGLVGGVLTSTAVGAAL-YWIT 242 L++FLV+ + +D+ QY+WGK GK K+ P++SP+KTL GL+GGVLT+ + A +T Sbjct: 180 LVIFLVVATELNDISQYLWGKSLGKIKVTPKVSPNKTLAGLLGGVLTTMLLAAIFGPLLT 239 Query: 243 PFNVWQAALVALTINILGFFGGFVLSAIKRDRGLKDWGAMIEGHGGMLDRVDSISFSAPI 302 P + + + I + GF G V+SAIKRD G+KD G ++ GHGG+LDR+DS+ ++AP+ Sbjct: 240 PMDWLHSLGAGVIIGLSGFCGDVVMSAIKRDFGVKDSGKLLPGHGGILDRLDSLIYTAPL 299 Query: 303 FFHILRYWWV 312 FFH Y++V Sbjct: 300 FFHFYHYFYV 309 >VC1936 [R] COG4589 Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase Vch Vibrio cholerae Length = 310 Score = 225 bits (573), Expect = 1e-58, Method: Compositional matrix adjust. Identities = 111/265 (41%), Positives = 163/265 (61%), Gaps = 2/265 (0%) Query: 42 NLNARIKAWWWMIGALAIAFWIGKTGVVVLFAFISLQALREFISVTYTRVGDHRALLWCF 101 L RI++WWWM+ + + + + F+S AL+EF+S+ TR+ D R + W + Sbjct: 40 ELKLRIRSWWWMVAIVFVVLQLPLNYTLFFVGFLSFMALKEFLSIVPTRMTDRRVIFWAY 99 Query: 102 FVFLPLQYVLIGMDWYGLFSILIPVYAFLLLPISASLSTDTKHFLERAAKVQWGLMICVY 161 +P QY + + WYG+F I IPVY FL LP+ L DTK F+ A + W +M+ V+ Sbjct: 100 LS-IPFQYYWLSIGWYGMFIIFIPVYVFLYLPMVMVLIGDTKGFIRSAGIIHWAMMLTVF 158 Query: 162 CISHVPALLTLPIEGFEGRNLQLIVFLVLTVQSSDVFQYVWGKLFGKRKLAPQISPSKTL 221 CISH+ LL LP + +L +++FL++ Q +DV QYVWGK FGK K+ P++SP+KT Sbjct: 159 CISHMAYLLVLPSLNPDAGSLGMLLFLLVMTQFNDVAQYVWGKSFGKHKIVPKVSPNKTW 218 Query: 222 EGLVGGVLTSTAVGA-ALYWITPFNVWQAALVALTINILGFFGGFVLSAIKRDRGLKDWG 280 +G +GG LT V A ++TP Q + + I + GF G V+S++KRD +KD Sbjct: 219 QGFIGGTLTVVTVSYFAAPYLTPLTAAQGLVGGVIIALSGFIGDLVISSVKRDLRIKDTS 278 Query: 281 AMIEGHGGMLDRVDSISFSAPIFFH 305 I GHGG+LDRVDS+ F+AP+FFH Sbjct: 279 QFIPGHGGILDRVDSLMFTAPLFFH 303