BLASTP 2.2.21 [Jun-14-2009] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0022.0239.p (458 letters) Database: COGmodified 192,987 sequences; 59,019,183 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value RSc2805 [F] COG0209 Ribonucleotide reductase, alpha subunit Rso ... 704 0.0 PA1156 [F] COG0209 Ribonucleotide reductase, alpha subunit Pae P... 612 e-175 CT827 [F] COG0209 Ribonucleotide reductase, alpha subunit Ctr Ch... 487 e-137 CPn0984 [F] COG0209 Ribonucleotide reductase, alpha subunit Cpn ... 477 e-134 VNG2384G [F] COG0209 Ribonucleotide reductase, alpha subunit Hbs... 468 e-131 >RSc2805 [F] COG0209 Ribonucleotide reductase, alpha subunit Rso Ralstonia solanacearum Length = 987 Score = 704 bits (1816), Expect = 0.0, Method: Compositional matrix adjust. Identities = 333/390 (85%), Positives = 356/390 (91%), Gaps = 5/390 (1%) Query: 3 ANDLWRKMLSMLFETGHPWITFKDPCNIRSPQQHVGVVHSSNLCTEITLNTNESEIAVCN 62 A LWRKML MLFETGHPWITFKDPCNIRSPQQHVGVVHSSNLCTEITLNTN+SEIAVCN Sbjct: 542 ALQLWRKMLGMLFETGHPWITFKDPCNIRSPQQHVGVVHSSNLCTEITLNTNDSEIAVCN 601 Query: 63 LGSVNLPAHLVNGE-----LDHAKLQKTIRTAMRMLDNVIDINYYAVKKARDSNLRHRPV 117 LGSVNL AH+V LDH KL+KT+RTAMRMLDNVIDINYYAVKKARDSNLRHRPV Sbjct: 602 LGSVNLVAHVVKQADGSYALDHDKLKKTVRTAMRMLDNVIDINYYAVKKARDSNLRHRPV 661 Query: 118 GMGIMGFQDCLHIKRVPYASMDAVEFADRSMEAVCYYAYMASTELAEERGRYASYRGSLW 177 G+GIMGFQD LH+ R+PYA+ AV+FAD SMEAVCYYAY ASTELAEERGRY++Y+GSLW Sbjct: 662 GLGIMGFQDALHVLRIPYATDAAVQFADTSMEAVCYYAYWASTELAEERGRYSTYKGSLW 721 Query: 178 DRGILPQDSLKLLAQERGGYLETDSTETLDWAALRARIAEHGMRNSNCVAIAPTATISNI 237 DRG+LPQDSLKLLAQERGGYLE D + T+DW LR RI +HGMRNSNCVAIAPTATISNI Sbjct: 722 DRGVLPQDSLKLLAQERGGYLEADLSSTMDWDGLRERIQQHGMRNSNCVAIAPTATISNI 781 Query: 238 IGVSACIEPTYQNLYVKSNLSGEFTEINEYLVRDLKARGLWDEVMVADLKYFDGSLAKID 297 IGVSACIEPTYQNLYVKSNLSGEFT +N+YLVRDLKARGLWDEVMVADLKYFDGSLA+ID Sbjct: 782 IGVSACIEPTYQNLYVKSNLSGEFTVVNDYLVRDLKARGLWDEVMVADLKYFDGSLARID 841 Query: 298 RIPQDLRDIYATAFEVDPSWLVEAASRRQKWIDQAQSLNIYMAGASGKRLDETYKLAWLR 357 RIPQDLRD+YATAFEV+P WLVEAASRRQKWIDQAQSLNIYMAGASGK LD+TYKLAWLR Sbjct: 842 RIPQDLRDLYATAFEVEPQWLVEAASRRQKWIDQAQSLNIYMAGASGKMLDDTYKLAWLR 901 Query: 358 GLKTTYYLRTIGATHTEKSTSRAGALNAVA 387 GLKTTYYLRTIGATH EKST G LNAV+ Sbjct: 902 GLKTTYYLRTIGATHVEKSTVSRGTLNAVS 931 >PA1156 [F] COG0209 Ribonucleotide reductase, alpha subunit Pae Pseudomonas aeruginosa Length = 963 Score = 612 bits (1577), Expect = e-175, Method: Compositional matrix adjust. Identities = 287/397 (72%), Positives = 341/397 (85%), Gaps = 3/397 (0%) Query: 1 VQANDLWRKMLSMLFETGHPWITFKDPCNIRSPQQHVGVVHSSNLCTEITLNTNESEIAV 60 VQA DLWRKMLSMLFETGHPW+TFKDPCN+RSPQQHVGVVHSSNLCTEITLNTN+ EIAV Sbjct: 542 VQAKDLWRKMLSMLFETGHPWLTFKDPCNLRSPQQHVGVVHSSNLCTEITLNTNKDEIAV 601 Query: 61 CNLGSVNLPAHLVNGELDHAKLQKTIRTAMRMLDNVIDINYYAVKKARDSNLRHRPVGMG 120 CNLGS+NL H+V+G+LD AKL+KT++TA+RMLDNVIDINYY+V +A++SN +HRPVG+G Sbjct: 602 CNLGSINLVNHIVDGKLDTAKLEKTVKTAVRMLDNVIDINYYSVPQAQNSNFKHRPVGLG 661 Query: 121 IMGFQDCLHIKRVPYASMDAVEFADRSMEAVCYYAYMASTELAEERGRYASYRGSLWDRG 180 IMGFQD L+++ +PY S A+ FAD+SMEA+ YYA AS +LA+ERG Y +++GSLW +G Sbjct: 662 IMGFQDALYLQHIPYGSDAAIAFADQSMEAISYYAIQASCDLADERGAYQTFQGSLWSQG 721 Query: 181 ILPQDSLKLLAQERGG-YLETDSTETLDWAALRARIAEHGMRNSNCVAIAPTATISNIIG 239 ILP DS K L +ERG Y+E D +ETLDWA LR R+ + G+RNSN +AIAPTATI+NI G Sbjct: 722 ILPIDSEKKLIEERGAKYIEVDLSETLDWAPLRERV-QKGIRNSNIMAIAPTATIANITG 780 Query: 240 VSACIEPTYQNLYVKSNLSGEFTEINEYLVRDLKARGLWDEVMVADLKYFDGSLAKIDRI 299 VS IEPTYQNLYVKSNLSGEFT IN YLVRDLKARGLWD VMV DLKY+DGS+ +I+RI Sbjct: 781 VSQSIEPTYQNLYVKSNLSGEFTVINPYLVRDLKARGLWDPVMVNDLKYYDGSVQQIERI 840 Query: 300 PQDLRDIYATAFEVDPSWLVEAASRRQKWIDQAQSLNIYMAGASGKRLDETYKLAWLRGL 359 PQDL+D+YATAFEV+ W+VEAASRRQKWIDQAQSLN+Y+AGASGK+LD TY++AW RGL Sbjct: 841 PQDLKDLYATAFEVETRWIVEAASRRQKWIDQAQSLNLYIAGASGKKLDVTYRMAWFRGL 900 Query: 360 KTTYYLRTIGATHTEKSTSRAGALNAVAVDGGADDVQ 396 KTTYYLR + AT TEKST G LNAV+ GG D +Q Sbjct: 901 KTTYYLRALAATSTEKSTINTGKLNAVSA-GGNDGLQ 936 >CT827 [F] COG0209 Ribonucleotide reductase, alpha subunit Ctr Chlamydia trachomatis Length = 1047 Score = 487 bits (1253), Expect = e-137, Method: Compositional matrix adjust. Identities = 230/377 (61%), Positives = 285/377 (75%), Gaps = 1/377 (0%) Query: 1 VQANDLWRKMLSMLFETGHPWITFKDPCNIRSPQQHVGVVHSSNLCTEITLNTNESEIAV 60 V+A DLWRKMLSMLFETGHPW+TFKDP NIRS Q H GVV SNLCTEI LN +E+E AV Sbjct: 627 VEAEDLWRKMLSMLFETGHPWMTFKDPSNIRSAQDHKGVVRCSNLCTEILLNCSETETAV 686 Query: 61 CNLGSVNLPAHLVNGELDHAKLQKTIRTAMRMLDNVIDINYYAVKKARDSNLRHRPVGMG 120 CNLGS+NL H+V LD KL +TI A+RMLDNVIDIN+Y K+A+++N HR +G+G Sbjct: 687 CNLGSINLVQHIVGDGLDEEKLSETISIAVRMLDNVIDINFYPTKEAKEANFAHRAIGLG 746 Query: 121 IMGFQDCLHIKRVPYASMDAVEFADRSMEAVCYYAYMASTELAEERGRYASYRGSLWDRG 180 +MGFQD L+ + YAS +AVEFAD S E + YYA AS LA+ERG Y+SY+GS WDRG Sbjct: 747 VMGFQDALYKLDISYASQEAVEFADYSSELISYYAIQASCLLAKERGTYSSYKGSKWDRG 806 Query: 181 ILPQDSLKLLAQERG-GYLETDSTETLDWAALRARIAEHGMRNSNCVAIAPTATISNIIG 239 +LP D+++LLA RG L+ D++ DW +R+ + EHGMR+ +AIAPTATISNIIG Sbjct: 807 LLPIDTIQLLANYRGEANLQMDTSSRKDWEPIRSLVKEHGMRHCQLMAIAPTATISNIIG 866 Query: 240 VSACIEPTYQNLYVKSNLSGEFTEINEYLVRDLKARGLWDEVMVADLKYFDGSLAKIDRI 299 V+ IEPTY++L+VKSNLSGEFT N YL+ LK G+WD M+ DLKYFDGSL +I+RI Sbjct: 867 VTQSIEPTYKHLFVKSNLSGEFTIPNVYLIEKLKKLGIWDADMLDDLKYFDGSLLEIERI 926 Query: 300 PQDLRDIYATAFEVDPSWLVEAASRRQKWIDQAQSLNIYMAGASGKRLDETYKLAWLRGL 359 P L+ I+ TAFE++P W++E ASRRQKWID QSLN+Y+A GK+L Y AW +GL Sbjct: 927 PDHLKHIFLTAFEIEPEWIIECASRRQKWIDMGQSLNLYLAQPDGKKLSNMYLTAWKKGL 986 Query: 360 KTTYYLRTIGATHTEKS 376 KTTYYLR+ AT EKS Sbjct: 987 KTTYYLRSSSATTVEKS 1003 >CPn0984 [F] COG0209 Ribonucleotide reductase, alpha subunit Cpn Chlamydophila pneumoniae CWL029 Length = 1044 Score = 477 bits (1227), Expect = e-134, Method: Compositional matrix adjust. Identities = 225/377 (59%), Positives = 283/377 (75%), Gaps = 1/377 (0%) Query: 1 VQANDLWRKMLSMLFETGHPWITFKDPCNIRSPQQHVGVVHSSNLCTEITLNTNESEIAV 60 V+A LWRKMLSML+ETGHPWITFKDP NIRS Q HVGVV SNLCTEI LN +ESE AV Sbjct: 625 VEAEVLWRKMLSMLYETGHPWITFKDPSNIRSNQDHVGVVRCSNLCTEILLNCSESETAV 684 Query: 61 CNLGSVNLPAHLVNGELDHAKLQKTIRTAMRMLDNVIDINYYAVKKARDSNLRHRPVGMG 120 CNLGS+NL H+ N +LD KL++TI A+R+LDNVID+N+Y +A+ +NL HR VG+G Sbjct: 685 CNLGSINLVEHIRNDKLDEEKLKETISIAIRILDNVIDLNFYPTPEAKQANLTHRAVGLG 744 Query: 121 IMGFQDCLHIKRVPYASMDAVEFADRSMEAVCYYAYMASTELAEERGRYASYRGSLWDRG 180 +MGFQD L+ + YAS +AVEF+D E + YYA +AS+ LA+ERG YASY GS WDRG Sbjct: 745 VMGFQDVLYELNISYASQEAVEFSDECSEIIAYYAILASSLLAKERGTYASYSGSKWDRG 804 Query: 181 ILPQDSLKLLAQERGGY-LETDSTETLDWAALRARIAEHGMRNSNCVAIAPTATISNIIG 239 LP D+++LL + RG + + D++ DW +R I ++GMRNS +AIAPTATISNIIG Sbjct: 805 YLPLDTIELLKETRGEHNVLVDTSSKKDWTPVRDTIQKYGMRNSQVMAIAPTATISNIIG 864 Query: 240 VSACIEPTYQNLYVKSNLSGEFTEINEYLVRDLKARGLWDEVMVADLKYFDGSLAKIDRI 299 V+ IEP Y++L+VKSNLSGEFT N YL++ LK GLWD M+ DLKYFDGSL +I+RI Sbjct: 865 VTQSIEPMYKHLFVKSNLSGEFTIPNTYLIKKLKELGLWDAEMLDDLKYFDGSLLEIERI 924 Query: 300 PQDLRDIYATAFEVDPSWLVEAASRRQKWIDQAQSLNIYMAGASGKRLDETYKLAWLRGL 359 P L+ ++ TAFE++P W++E SRRQKWID SLN+Y+A GK+L Y AW +GL Sbjct: 925 PNHLKKLFLTAFEIEPEWIIECTSRRQKWIDMGVSLNLYLAEPDGKKLSNMYLTAWKKGL 984 Query: 360 KTTYYLRTIGATHTEKS 376 KTTYYLR+ AT EKS Sbjct: 985 KTTYYLRSQAATSVEKS 1001 >VNG2384G [F] COG0209 Ribonucleotide reductase, alpha subunit Hbs Halobacterium sp. NRC-1 Length = 804 Score = 468 bits (1203), Expect = e-131, Method: Compositional matrix adjust. Identities = 216/377 (57%), Positives = 274/377 (72%) Query: 1 VQANDLWRKMLSMLFETGHPWITFKDPCNIRSPQQHVGVVHSSNLCTEITLNTNESEIAV 60 V A DLWR ML+ LFETGHPW+TFKDPCN+RSPQ H G V SSNLCTEITLNT+E E AV Sbjct: 390 VDATDLWRTMLTRLFETGHPWLTFKDPCNVRSPQDHAGTVRSSNLCTEITLNTSEEETAV 449 Query: 61 CNLGSVNLPAHLVNGELDHAKLQKTIRTAMRMLDNVIDINYYAVKKARDSNLRHRPVGMG 120 CNLGSVNL HL +G++D +L +T+ TAMRMLDNV+D+N+Y + A SN+RHRPVG+G Sbjct: 450 CNLGSVNLARHLDDGDIDREQLSETVETAMRMLDNVVDLNFYPTENAERSNMRHRPVGLG 509 Query: 121 IMGFQDCLHIKRVPYASMDAVEFADRSMEAVCYYAYMASTELAEERGRYASYRGSLWDRG 180 +MGF D L RVP AS DA++ AD E V Y+A AS +LA ERG Y SY GS WDR Sbjct: 510 VMGFHDALQQMRVPMASDDALDRADALQEYVAYHAIGASADLAAERGTYESYEGSKWDRD 569 Query: 181 ILPQDSLKLLAQERGGYLETDSTETLDWAALRARIAEHGMRNSNCVAIAPTATISNIIGV 240 + PQD++ L ERG + E LDW+ +R R+A HGMRNSN +A+APTATIS I G Sbjct: 570 VFPQDTVDRLESERGREIPVPREERLDWSDVRQRVATHGMRNSNTMAVAPTATISTIAGT 629 Query: 241 SACIEPTYQNLYVKSNLSGEFTEINEYLVRDLKARGLWDEVMVADLKYFDGSLAKIDRIP 300 + IEP Y NLYVKSN+SG+FT +N+ LV DL+ R LW E + L Y DGS+ ++D +P Sbjct: 630 TPSIEPVYSNLYVKSNMSGDFTVVNDRLVADLEERDLWTEELRDKLTYHDGSVQELDAVP 689 Query: 301 QDLRDIYATAFEVDPSWLVEAASRRQKWIDQAQSLNIYMAGASGKRLDETYKLAWLRGLK 360 +D++++Y TAFE+DP + A+RR WIDQ+QS+N++ G +L E Y+ AW GLK Sbjct: 690 EDVQELYRTAFEIDPRHQLRLAARRGVWIDQSQSVNVFFPETDGSKLSEVYQTAWELGLK 749 Query: 361 TTYYLRTIGATHTEKST 377 TTYYLRT+GA+ EK+T Sbjct: 750 TTYYLRTLGASQIEKTT 766